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支持性社区氛围对消费者公民行为的影响——基于消费者增权视角

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湖北文理学院学报 2024年第5期45卷 52-58页

作者：吴佳荷新疆财经大学工商管理学院新疆乌鲁木齐830012

基于SOR理论探讨支持性社区氛围对消费者公民行为的影响,采用问卷调查方法收集有效问卷350份并进行实证分析。结果显示:支持性社区氛围正向影响消费者公民行为;消费者增权在支持性社区氛围对消费者公民行为的影响中起部分中介作用;主动... 详细信息

基于SOR理论探讨支持性社区氛围对消费者公民行为的影响,采用问卷调查方法收集有效问卷350份并进行实证分析。结果显示:支持性社区氛围正向影响消费者公民行为;消费者增权在支持性社区氛围对消费者公民行为的影响中起部分中介作用;主动性人格正向调节消费者增权和消费者公民行为之间的关系,还调节消费者增权的中介作用。

关键词：支持性社区氛围消费者公民行为消费者增权 SOR理论

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主播-品牌关联度对消费者购买意愿的影响

重庆文理学院学报（社会科学版） 2024年第2期43卷 40-51页

作者：陈炜吴佳荷新疆财经大学工商管理学院新疆乌鲁木齐830012

主播作为品牌直播间的“前沿”代言人,在品牌建设中扮演着重要角色,但主播的代言效果并不总是尽如人意,这取决于主播与品牌之间的关联度。目前对于主播-品牌关联度是否会对消费者购买意愿产生影响尚不明晰。文章基于Hovland说服模型,通... 详细信息

主播作为品牌直播间的“前沿”代言人,在品牌建设中扮演着重要角色,但主播的代言效果并不总是尽如人意,这取决于主播与品牌之间的关联度。目前对于主播-品牌关联度是否会对消费者购买意愿产生影响尚不明晰。文章基于Hovland说服模型,通过问卷调查法探讨主播-品牌关联度对消费者购买意愿的影响以及这一影响发生的内在机制和边界条件。研究结果表明:主播-品牌关联度对消费者购买意愿具有显著正向影响;在此过程中,消费者自我-品牌联结发挥着部分中介作用。此外,由品牌知识的调节效应分析发现,其能够正向调节主播-品牌关联度与消费者自我-品牌联结的关系。这将丰富直播营销对消费者购买意愿影响的相关研究,为商家有针对性地选择主播,提升品牌代言效果提供重要参考。

关键词：说服理论主播-品牌关联度自我-品牌联结购买意愿

孔隙对粒状海冰单轴压缩强度影响的数值模拟研究

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海洋学报 2024年第6期46卷 40-50页

作者：吴家和王庆凯李金钊卢鹏李志军大连理工大学海岸和近海工程国家重点实验室辽宁大连116023 自然资源部中国极地研究中心上海200136

强度是影响海冰与结构物相互作用关系的关键性质之一。海冰内部的卤水胞和气泡等孔隙结构对海冰的强度有重要影响。为从细观角度探究冰内孔隙含量、形状和尺寸等海冰结构参数对海冰力学性质的影响,基于离散元方法,建立了包含孔隙的数值... 详细信息

强度是影响海冰与结构物相互作用关系的关键性质之一。海冰内部的卤水胞和气泡等孔隙结构对海冰的强度有重要影响。为从细观角度探究冰内孔隙含量、形状和尺寸等海冰结构参数对海冰力学性质的影响,基于离散元方法,建立了包含孔隙的数值海冰模型,模拟粒状冰在平行和垂直冰面方向加载脆性破坏的单轴压缩过程。孔隙尺寸设置为符合均匀分布、标准正态分布和Gamma分布等不同随机分布类型。数值模拟试验结果表明孔隙率是影响海冰强度的主要因素,海冰单轴压缩强度和弹性模量均随孔隙的增加而减小。当压缩应力达到极值时,冰内裂缝迅速扩展。对于圆形孔隙,裂缝主要沿荷载施加方向开展,因此平行冰面方向试样破坏时多表现为大裂缝;对于椭圆形孔隙,裂缝易扩展形成裂缝带。当孔隙率相同时,孔隙尺寸随机分布类型和位置对单轴压缩强度和弹性模量影响不大,但影响冰内裂缝的扩展方式。

关键词：海冰孔隙单轴压缩强度弹性模量离散元

Biomaterials reinforced MSCs transplantation for spinal cord injury repair

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Asian Journal of Pharmaceutical Sciences 2022年第1期17卷 4-19页

作者： Teng Ma jiahe wu Jiafu Mu Jianqing Gao Institute of Pharmaceutics College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Dr.Li Dak Sum&Yip Yio Chin Center for Stem Cell and Regenerative Medicine Zhejiang UniversityHangzhou 310058China Department of Clinical Pharmacology Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang ProvinceAffiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006China

Due to the complex pathophysiological mechanism, spinal cord injury (SCI) has become one of the most intractable central nervous system (CNS) diseases to therapy. Stem cell transplantation, mesenchymal stem cells (MSCs) particularly, appeals to more and more attention along with the encouraging therapeutic results for the functional regeneration of SCI. However, traditional cell transplantation strategies have some limitations, including the unsatisfying survival rate of MSCs and their random diffusion from the injection site to ambient tissues. The application of biomaterials in tissue engineering provides a new horizon. Biomaterials can not only confine MSCs in the injured lesions with higher cell viability, but also promote their therapeutic efficacy. This review summarizes the strategies and advantages of biomaterials reinforced MSCs transplantation to treat SCI in recent years,which are clarified in the light of various therapeutic effects in pathophysiological aspects of SCI.

关键词： MSCs transplantation Spinal cord injury Biomaterials Functional regeneration

Molecular Design of Conjugated Small Molecule Nanoparticles for Synergistically Enhanced PTT/PDT

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Nano-Micro Letters 2020年第11期12卷 25-38页

作者： Wei Shao Chuang Yang Fangyuan Li jiahe wu Nan Wang Qiang Ding Jianqing Gao Daishun Ling Institute of Pharmaceutics and Hangzhou Institute of Innovative Medicine College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058ZhejiangPeople’s Republic of China Jiangsu Breast Disease Center The First Affiliated Hospital with Nanjing Medical UniversityNanjing 210029JiangsuPeople’s Republic of China

Simultaneous photothermal therapy(PTT)and photodynamic therapy(PDT)is beneficial for enhanced cancer therapy due to the synergistic *** materials developed for synergistic PTT/PDT are generally multicomponent agents that need complicated preparation procedures and be activated by multiple laser *** emerging monocomponent diketopyrrolopyrrole(DPP)-based conjugated small molecular agents enable dual PTT/PDT under a single laser irradiation,but suffer from low singlet oxygen quantum yield,which severely restricts the therapeutic ***,we report acceptor-oriented molecular design of a donor-acceptor-donor(D-A-D)conjugated small molecule(IID-ThTPA)-based phototheranostic agent,with isoindigo(IID)as selective acceptor and triphenylamine(TPA)as *** strong D-A strength and narrow singlet-triplet energy gap endow IID-ThTPA nanoparticles(IID-ThTPA NPs)high mass extinction coefficient(18.2 L g^-1 cm^-1),competitive photothermal conversion efficiency(35.4%),and a dramatically enhanced singlet oxygen quantum yield(84.0%)comparing with previously reported monocomponent PTT/PDT *** a high PTT/PDT performance of IID-ThTPA NPs achieved superior tumor cooperative eradicating capability in vitro and in vivo.

关键词： Molecular design Isoindigo Conjugated small molecule nanoparticles Singlet-triplet energy gap Synergistic PTT/PDT

Rapid and effective treatment of traumatic spinal cord injury using stem cell derived exosomes

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Asian Journal of Pharmaceutical Sciences 2021年第6期16卷 806-815页

作者： Jiafu Mu jiahe wu Jian Cao Teng Ma Liming Li Shiqing Feng Jianqing Gao College of Pharmaceutical Sciences Zhejiang UniversityHangzhou 310058China Pilot National Laboratory for Marine Science and Technology Qingdao 266137China Department of Orthopedics Tianjin Medical University General HospitalTianjin 300052China International Science and Technology Cooperation Base of Spinal Cord Injury Tianjin Key Laboratory of Spine and Spinal Cord InjuryDepartment of OrthopedicsTianjin Medical University General HospitalTianjin 300052China Dr.Li Dak Sum&Yip Yio Chin Center for Stem Cell and Regenerative Medicine Zhejiang UniversityHangzhou 310058China

Traumatic spinal cord injury is a fatal acute event without effective clinical *** the trauma,immediate neural protection and microenvironment mitigation are vitally important for nerve tissue repair,where stem cell-based therapies could be eclipsed by the deficiency of cells due to the hostile microenvironment as well as the transport and preservation *** emergency strategies are required to be convenient,biocompatible,and ***,we assess an emergency cell-free treatment using mesenchymal stem cell-derived exosomes,which have proven capable of comprehensive mitigation of the inhibitory lesion *** clinically validated fibrin glue is utilized to encapsulate the exosomes and in-situ gelates in transected rat spinal cords to provide a substrate for exosome delivery as well as nerve tissue *** emergency treatment alleviates the inflammatory and oxidative microenvironment,inducing effective nerve tissue repair and functional *** therapy presents a promising strategy for effective emergency treatment of central nervous system trauma。

关键词： Exosome Fibrin glue Spinal cord injury Emergency treatment

Induction of chromosomal inversion by integration of T-DNA in the rice genome

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Journal of Genetics and Genomics 2010年第3期37卷 189-196页

作者： Chuanfeng Zhu,jiahe wu,Chaozu He State Key Laboratory of Plant Genomics,Institute of Microbiology,Chinese Academy of Sciences,Beijing 100101,China State Key Laboratory of Plant Genomics Institute of Microbiology Chinese Academy of Sciences Beijing 100101 China

Transfer DNA （T-DNA） of Agrobacterium tumefaciens integration in the plant genome may lead to rearrangements of host plant chromosomal fragments, including inversions. However, there is very little information concerning the inversion. The present study re- ports a transgenic rice line selected from a T-DNA tagged population, which displays a semi-dwarf phenotype. Molecular analysis of this mutant indicated an insertion of two tandem copies of T-DNA into a locus on the rice genome in a head to tail mode. This insertion of T-DNA resulted in the inversion of a 4.9 Mb chromosomal segment. Results of sequence analysis suggest that the chromosomal inversion resulted from the insertion of T-DNA with the help of sequence microhomology between insertion region of T-DNA and target sequence of the host plant.

关键词： Agrobacterium tumefaciens-mediated transformation (ATMT) T-DNA chromosomal inversion

Overexpressing rice lesion simulating disease 1-like gene(OsLOL1)in Gossypium hirsutum promotes somatic embryogenesis and plant regeneration

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Journal of Cotton Research 2020年第3期3卷 149-155页

作者： WANG Zhian WANG Peng HU Guang XIAO Juanli ZHANG Anhong LUO Xiaoli wu jiahe Institute of Cotton Research/Shanxi Academy of Agricultural Sciences/Shanxi Agricultural University Yuncheng 044000China State Key Laboratory of Cotton Biology/Institute of Cotton Research Chinese Academy of Agricultural SciencesAnyang 455000China State Key Laboratory of Plant Genomics/Institute of Microbiology Chinese Academy of SciencesBeijing 100101China

Background:Cotton somatic embryogenesis is difficult or rarely frequent to present,which has limited gene function identification and biotechnological ***,we employed a rice key somatic embryogenesis-related gene,rice lesion simulating disease 1-like gene(OsLOL1),to develop transgenic cotton callus for evaluating its function in ectopic ***:Overexpressing OsLOL1 can promote cotton callus to form embryogenic callus,not only shortening time but also increasing transition of somatic callus cells to embryogenic callus *** the regenerating plantlets per transgenic OsLOL1 embryogenic callus were significantly higher than those in the control transformed with empty *** of physiological and biochemical showed that OsLOL1 can repress cotton superoxide dismutase 1 gene(GhSOD1)expression,possibly resulting in reactive oxidant species(ROS)accumulation in transgenic callus *** OsLOL1-overexpressed embryogenic callus exhibited higherα-amylase activity compared with the control,resulting from the promotion of OsLOL1 to cotton amylase 7 gene(GhAmy7)and GhAmy8 ***:The data showed that OsLOL1 could be used as a candidate gene to transform cotton to increase its somatic embryogenesis capacity,facilitating gene function analysis and molecular breeding in cotton.

关键词： Gossypium hirsutum Somatic embryogenesis OsLOL1 GhSOD1 GhAmy7

Coupled simulation of fluid-particle interaction for large complex granules:A resolved CFD-DEM method for modelling the airflow in a vertical fixed bed of irregular sinter particles

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Particuology 2024年第7期90卷 292-306页

作者： Chengzhi Li Yu Zhang jiahe Shen Wei Zhang The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081China Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081China School of Transportation and Logistics Engineering Wuhan University of TechnologyWuhan 430063China Centre for Bulk Solids and Particulate Technologies The University of NewcastleCallaghan NSW 2308Australia

A resolved CFD-DEM method is proposed to simulate the fluid-particle interaction for large complex *** airflow in a vertical sinter fixed bed is numerically studied using this *** multi-sphere clumped method is used to create irregular sinter particles in *** immersed boundary method and dynamic cell refinement are applied to describe the fluid flow around particles with higher resolution,by which the fluid-particle interaction can be simulated more *** simulation results presented the packing voidage distributions and the airflow fields in the sinter beds of different single and mixed particle size *** bed pressure drops were simulated and the results were compared with the corresponding experimental *** good agreement indicated that the proposed resolved CFD-DEM method is an effective tool to model the fluid-particle interaction for irregular large granules in the gas-solid multi-phase systems.

关键词： Resolved CFD-DEM method Irregular sinter particles Multi-sphere clumped method Immersed boundary method Dynamic cell refinement