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Electromagnetic Processing of Materials at the Department Inorganic-Nonmetallic Materials

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Journal of Iron and Steel Research(International) 2012年第S1期19卷 135-140页

作者： HALBEDEL Bernd KRIEGER Uwe werner michael TORRES Jose Oskar SCHADEWALD Uwe QUIROZ Pamela Ilmenau University of Technology P.O. 100565D-98684 IlmenauGermany Ilmenau Technische Glaswerke Ilmenau GmbH Am Vogelherd 7D-98684 IlmenauGermany

This paper illustrates an overview of current research activities in the working group 'Electromagnetic Processing of Materials' of the department Inorganic-Nonmetallic *** are 'Electromagnetic module to flow impact in special melting plants for the production of High-tech glasses', 'Numerical study of EM controlled flow in crystallizers of inorganic materials', 'Design,test and optimization of sophisticated magnet systems for Lorentz force velocimetry in electrially low conducting fluids', 'Magnetic ion manipulation in glass melts with Kelvin force', 'Electromechanical dry t'me milling of raw materials' and 'Synthesis,characterization and application of Titatium doped hexaferrites'.The primary results are presented here.

关键词： Lorentz force Kelvin force magnet system glass melt crystallization grinding synthesis hexaferrite

Lorentz Force Velocimetry for Poorly Conducting Fluids-Development and Validation of a Novel Flow Rate Measurement Device

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Journal of Iron and Steel Research(International) 2012年第S2期19卷 613-616页

作者： WEGFRASS Andre RESAGK Christian DIETHOLD Christian FRHLICH Thomas werner michael HALBEDEL Bernd THESS Andre Institute of Thermodynamics and Fluid Mechanics Department of Mechanical EngineeringIlmenau University of Technology Institute of Process Measurement and Sensor Technology Department of Mechanical EngineeringIlmenau University of Technology Institute of Inorganic-nonmetallic Materials Department of Mechanical EngineeringIlmenau University of Technology

The paper demonstrated the feasibility of Lorentz Force Velocimetry for flow rate measurements of weakly conducting electrolytes using experimental results on salt water flow exposed to a permanent magnet *** innovative flow measurement technique allows the non-contact determination of flow rates and relies on the interaction between a magnetic field and a moving conducting *** an electrically conducting fluid moves through the magnetic field a Lorentz force is generated and acts on the measurement *** present report provides an overview about the experimental setups and the first measurement results.

关键词： Lorentz force velocimetry flow measurement electrolytes non-contact measurement

Landscape of global urban environmental resistome and its association with local socioeconomic and medical status

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Science China(Life Sciences) 2024年第6期67卷 1292-1301页

作者： Jun Wu Yige Hu michael H Perlin David Danko Jun Lu Manuela Oliveira Johannes werner Maria M Zambrano Maria A Sierra Olayinka O Osuolale Paweł Łabaj Nicolás Rascovan Nur Hazlin Hazrin-Chong Soojin Jang Haruo Suzuki Marina Nieto-Caballero Bharath Prithiviraj Patrick K H Lee Agnieszka Chmielarczyk Anna Różańska Yongxiang Zhao Lan Wang Christopher E Mason Tieliu Shi Center for Bioinformatics and Computational Biology and the Institute of Biomedical SciencesSchool of Life SciencesEast China Normal UniversityShanghai 200241China Department of Biology Program on Disease EvolutionUniversity of LouisvilleLouisville 40292USA Weill Cornell Medicine New York 10065USA The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine New York 10065USA Department of Pulmonary Medicine Shanghai Chest HospitalShanghai Jiao Tong UniversityShanghai 200025China i3S-Instituto de Investiga玢o e Inova玢o em Saúde Universidade do PortoPorto 4050-290Portugal Ipatimup-Instituto de Patologia e Imunologia Molecular da Universidade do Porto Porto 4200-465Portugal Departamento de Biologia Faculdade de CiênciasUniversidade do PortoPorto 4050-290Portugal High Performance and Cloud Computing Group Zentrum für Datenverarbeitung(ZDV)Eberhard Karls University of TübingenW鋍hterstra遝7672074TübingenGermany Corporación Corpogen Research Center Bogotá110311Colombia Applied Environmental Metagenomics and Infectious Diseases Research(AEMIDR) Department of Biological SciencesElizade UniversityIlara-Mokin 340271Nigeria Maopolska Centre of Biotechnology Jagiellonian UniversityKraków 30-005Poland Aix-Marseille Université Mediterranean Institute of OceanologyUniversitéde ToulonCNRSIRDUM 110Marseille 83041France Department of Biological Sciences and Biotechnology Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 UKM BangiSelangor Institut Pasteur Korea Seoul 13488Republic of Korea Faculty of Environment and Information Studies Keio UniversityFujisawaKanagawa 252-0882Japan University of Colorado at Boulder CivilEnvironmental and Architectural DepartmentBoulder 80303USA Brooklyn College of the City University of New York Brooklyn 11210USA School of Energy and Environment City University of Hong KongHong Kong 999077China Department of Microbiology Faculty of MedicineJagiellonian UniversityKraków 30-005Poland Biological Targeting Diagnosis and The

Antimicrobial resistance(AMR)poses a critical threat to global health and development,with environmental factors—particularly in urban areas—contributing significantly to the spread of antibiotic resistance genes(ARGs).However,most research to date has been conducted at a local level,leaving significant gaps in our understanding of the global status of antibiotic resistance in urban *** address this issue,we thoroughly analyzed a total of 86,213 ARGs detected within 4,728 metagenome samples,which were collected by the Meta SUB International Consortium involving diverse urban environments in 60 cities of 27 countries,utilizing a deep-learning based *** findings demonstrated the strong geographical specificity of urban environmental resistome,and their correlation with various local socioeconomic and medical *** also identified distinctive evolutionary patterns of ARG-related biosynthetic gene clusters(BGCs)across different countries,and discovered that the urban environment represents a rich source of novel *** study provides a comprehensive overview of the global urban environmental resistome,and fills a significant gap in our knowledge of large-scale urban antibiotic resistome analysis.

关键词： urban environment metagenome antibiotic resistance resistance diversity biosynthetic gene clusters

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圆片级测试MEMS器件的解决之道

今日电子 2008年第9期 47-48页

作者： Frank-michael werner Joshuam.Preston SUSS MicroTec公司

MEMS产业发展十分迅速，但是人们常常忽视对其的早期测试。乍一看来，MEMS器件和传统IC器件的制造十分相似，但是，由于MEMS器件具有额外的机械部分（大多是可活动的）和封装，这些部分的成本通常占其总成本的大部分，因此MEMS器件的特... 详细信息

MEMS产业发展十分迅速，但是人们常常忽视对其的早期测试。乍一看来，MEMS器件和传统IC器件的制造十分相似，但是，由于MEMS器件具有额外的机械部分（大多是可活动的）和封装，这些部分的成本通常占其总成本的大部分，因此MEMS器件的特性比传统IC器件要复杂得多，而且各不相同。

关键词： MEMS器件测试圆片级产业发展 IC器件机械部分总成本

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快速测定聚丙烯酰胺的分子参数

实验与分析 2010年第6期 36-37页

作者： Dreke Lohmann Christoph Johann werner-michael Kulicke Dierk Rossner 德国汉堡大学工艺和高分子化学研究所 Wyatt公司

聚丙烯酰胺类水溶性的聚合物所呈现出的不同程度的老化现象，可能明显影响其性质。本文借助于非对称流分离系统法（AFFFF）．可以快速、可靠地测定聚丙烯酰胺的分子参数。相对于经典的尺寸排阻色谱（SEC）而言．这种分离方法具有一些独... 详细信息

聚丙烯酰胺类水溶性的聚合物所呈现出的不同程度的老化现象，可能明显影响其性质。本文借助于非对称流分离系统法（AFFFF）．可以快速、可靠地测定聚丙烯酰胺的分子参数。相对于经典的尺寸排阻色谱（SEC）而言．这种分离方法具有一些独特的优点。

关键词：聚丙烯酰胺类分子参数快速测定尺寸排阻色谱老化现象分离系统分离方法聚合物

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晶圆级MEMS测试

集成电路应用 2007年第3期24卷 87-87页

作者： Frank-michael werner Joshua Preston SUSS MicroTec Test Systems GmbH

MEMS产业正处于一个飞速发展的阶段，但MEMS的早期测试仍是一个很大程度上被忽略的领域。MEMS的制造与经典的IC制造类似，但MEMS器件通常含有机械部分，因此封装占整个MEMS器件成本的大部分。由很多因素决定了器件要在封装之前进行测试... 详细信息

MEMS产业正处于一个飞速发展的阶段，但MEMS的早期测试仍是一个很大程度上被忽略的领域。MEMS的制造与经典的IC制造类似，但MEMS器件通常含有机械部分，因此封装占整个MEMS器件成本的大部分。由很多因素决定了器件要在封装之前进行测试．原因之一就是封装工艺的成本太高。在最终封装之后测出器件失效不但费钱，还浪费了R＆D、工艺过程和代工时间。在早期对产品进行功能测试，可靠性分析及失效分析可以降低产品成本和加速上市时间，对于微系统的产业化来说非常关键。

关键词： MEMS器件功能测试封装工艺产品成本晶圆 IC制造上市时间 EMS产业

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大陆集团总部

现代装饰 2024年第3期 32-41页

作者： Arsen Aliverdiev(设计) michael Bertram(设计) Kerstin El-Khawad(设计) Gunter Fleitz(设计) Eva Perez Fons(设计) Lisa Holler(设计) Leticia Hutchings(设计) Peter Ippolito(设计) Christiane Klinner(设计) Susann Kreplin(设计) Frank Lakmann(设计) Tim Lessmann(设计) Eleonora Mannisi(设计) Thomas Mura(设计) Maria Cristina Orizzonte(设计) Jana Stumpe(设计) Bradley Wheeler(设计) Elisabed Zautashvili(设计) werner Huthmacher(摄影) Ippolito Fleitz Group(摄影) 不详

“The Future in Motion”是大陆集团的座右铭,而大陆集团的品牌“Continental”则代表着面向未来、可持续发展和团结协作的理念。由于原集团总部的面积不再能满足公司的未来发展,大陆集团决定在德国汉诺威毗邻城市森林的位置新建一座... 详细信息

“The Future in Motion”是大陆集团的座右铭,而大陆集团的品牌“Continental”则代表着面向未来、可持续发展和团结协作的理念。由于原集团总部的面积不再能满足公司的未来发展,大陆集团决定在德国汉诺威毗邻城市森林的位置新建一座总部。新总部的设计以共享办公为概念,可为多达2400名员工提供工作场所。新楼经过五年建设,于2023年12月投入使用。

关键词：集团总部德国汉诺威可持续发展团结协作大陆座右铭

Prodromal Parkinson’s disease: hype or hope for disease-modification trials?

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Translational Neurodegeneration 2022年第1期11卷 777-789页

作者： Philipp Mahlknecht Kathrin Marini Mario Werkmann werner Poewe Klaus Seppi Department of Neurology Innsbruck Medical University6020 InnsbruckAustria

The ultimate goal in Parkinson’s disease (PD) research remains the identification of treatments that are capable of slowing or even halting the progression of the disease. The failure of numerous past disease-modification trials in PD has been attributed to a variety of factors related not only to choosing wrong interventions, but also to using inadequate trial designs and target populations. In patients with clinically established PD, neuronal pathology may already have advanced too far to be modified by any intervention. Based on such reasoning, individuals in yet prediagnostic or prodromal disease stages, may provide a window of opportunity to test disease-modifying strategies. There is now sufficient evidence from prospective studies to define diagnostic criteria for prodromal PD and several approaches have been studied in observational cohorts. These include the use of PD-risk algorithms derived from multiple established risk factors for disease as well as follow-up of cohorts with single defined prodromal markers like hyposmia, rapid eye movement sleep behavior disorders, or PD gene carriers. In this review, we discuss recruitment strategies for disease-modification trials in various prodromal PD cohorts, as well as potential trial designs, required trial durations, and estimated sample sizes. We offer a concluding outlook on how the goal of implementing disease-modification trials in prodromal cohorts might be achieved in the future.

关键词： Neuroprotection Preclinical Prevention Epidemiology Probability Randomized controlled trial Preventive Neuroprotective

Arabidopsis HIPP proteins regulate endoplasmic reticulum-associated degradation of CKX proteins and cytokinin responses.

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Molecular Plant 2021年第11期14卷 1918-1934页

作者： Tianqi Guo Henriette Weber michael C.E.Niemann Lisa Theisl Georgeta Leonte Ondrej Novak Tomas werner Institute of Biology/Applied Genetics Dahlem Centre of Plant Sciences(DCPS)Freie Universitat BerlinAlbrecht-Thaer-Weg 614195 BerlinGermany Guangdong Provincial Key Laboratory of Conservation and Precision Utilization of Characteristic Agricultural Resources in Mountainous Areas School of Life Science of Jiaying University514015 Mei ZhouChina lnstitute of Biology University of GrazSchubertstraβe 518010 GrazAustria Laboratory of Growth Regulators Centre of the Region Hana for Biotechnological and Agricultural ResearchPalacky University and Institute of Experimental Botany ASCR78371 OlomoucCzech Republic

Eukaryotic organisms are equipped with quality-control mechanisms that survey protein folding in the endoplasmic reticulum (ER) and remove non-native proteins by ER-associated degradation (ERAD). Recent research has shown that cytokinin-degrading CKX proteins are subjected to ERAD during plant development. The mechanisms of plant ERAD, including the export of substrate proteins from the ER, are not fully understood and the molecular components involved in the ERAD of CKX are unknown. We show that heavy metal-associated isoprenylated plant proteins (HIPP) interact specifically with CKX proteins synthesized in the ER and processed by ERAD. CKX-HIPP protein complexes were detected at the ER as well as in the cytosol, suggesting that the complexes involve retrotranslocated CKX protein species. Altered CKX levels in HIPP-overexpressing and higher-order hipp mutant plants suggest that the studied HIPP proteins control the ERAD of CKX. Deregulation of CKX proteins caused corresponding changes in the cytokinin signaling activity and triggered typical morphological cytokinin responses. Notably, transcriptional repression of HIPP genes by cytokinin indicates a feedback regulatory mechanism of cytokinin homeostasis and signaling responses. Moreover, the loss of HIPP genes constitutively activates the unfolded protein response and compromises the ER stress tolerance, supporting the conclusion that HIPPs represent novel functional components of plant ERAD.

关键词： Arabidopsis remove folding