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Pilot plant study on ozonation and biological activated carbon process for drinking water treatment

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Journal of Environmental Sciences 2006年第2期18卷 232-235页

作者： KONG Ling-yu ZHANG Xiao-jian wang Zhan-sheng Department of Environmental Science and Engineering Tsinghua University Beijing 100084 China

A study on advanced drinking water treatment was conducted in a pilot scale plant taking water from conventional treatment process. Ozonation-biological activated carbon process （O3-BAC） and granular activated carbon process （GAC） were evaluated based on the following parameters： CODMn, UV254, total organic carbon （TOC）, assimilable organic carbon （AOC） and biodegradable dissolved organic carbon （BDOC）. In this test, the average removal rates of CODMn, UV254 and TOC in O3-BAC were 18.2%, 9.0% and 10.2% higher on （AOC） than in GAC, respectively. Ozonation increased 19.3-57.6 μg Acetate-C/L in AOC-P17, 45.6-130.6 μg Acetate-C/L in AOC-NOX and 0.1-0.5 mg/L in BDOC with ozone doses of 2 8 mg/L. The optimum ozone dose for maximum AOC formation was 3 mgO3/L. BAC filtration was effective process to improve biostability.

关键词： ozonation biological activated carbon CODMn UV254 TOC AOC BDOC biostability

Identification of methylation profile of HOX genes in extrahepatic cholangiocarcinoma

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World Journal of Gastroenterology 2011年第29期17卷 3407-3419页

作者： Yi Shu Bing wang Ji wang jian-Ming wang sheng-Quan Zou General Surgery Department of Tongji Hospital Tongji Medical College of Huazhong University of Science and Technology1095 Jiefang AvenueWuhan 430030Hubei ProvinceChina

AIM:To identify methylation profile and novel tumor marker of extrahepatic cholangiocarcinoma(CCA)with high throughout ***:Differential methylation profile was compared between normal bile duct epithelial cell lines and CCA cell lines by methyl-DNA immunoprecipitation (MeDIP)***-polymerase chain reaction (BSP)was performed to identify the methylated allels of target *** of target genes was investigated before and after the treatment with DNA demethylating *** of candidate genes was also evaluated by immunofluorescence in 30 specimens of CCA tissues and 9 normal bile duct ***:Methylation profile of CCA was identified with MeDIP microarray in the respects of different gene functions and signaling ***,97 genes with hypermethylated CpG islands in the promoter region were homeobox *** top 5 hypermethylated homeobox genes validated by BSP were HOXA2(94.29%),HOXA5(95.38%),HOXA11 (91.67%),HOXB4(90.56%)and HOXD13(94.38%).Expression of these genes was reactivated with 5’-aza2’-*** expression differences were found between normal bile duct and extrahepatic CCA tissues(66.67%-100%vs 3.33%-10%).CONCLUSION:HOXA2,HOXA5,HOXA11,HOXB4 and HOXD13 may work as differential epigenetic biomarkers between malignant and benign biliary tissues.

关键词： DNA methylation Epigenetic Promoter microarray Cholangiocarcinoma

MicroRNA-mediated Silencing of RhoC Inhibits Tumor Invasion and Increases Chemosensitivity to Paclitaxel in SKOV3 Cells in vitro

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Chemical Research in Chinese Universities 2011年第1期27卷 70-74页

作者： PAN Ying DU Zhen-wu LENG Wei-chun ZHOU Jia-wen wang Ying-jian sheng Min-jia wang Jun-rong ZHANG Gui-zhen China-Japan Union Hospital of Jilin University Changchun 130031 P. R. China

RhoC is a member of the Ras-homologous family of genes which are implicated in tumorigenesis and tumor progression. Up-regulation of RhoC is associated with tumor progression in ovarian carcinoma and RhoC is significantly correlated with the invasive capability of ovarian cancer cell lines in vitro, We developed a system that blocks RhoC in the human ovarian cancer SKOV3 cells using specific MicroRNA（miRNA） interference. By transfecting SKOV3 cells with the plasmid vector to express specific MiRNA that targets human RhoC, we were able to establish a stable clone in which RhoC expression was significantly downregulated. This resulted in the decreased invasive potential of SKOV3 cells as well as increased chemosensitivity to paclitaxel. RhoC involves in invasion and chemosensitivity of SKOV3, indicating that RhoC may be a promising therapeutic target for ovarian cancer.

关键词： RhoC gene miRNA SKOV3 cell Cell invasion Paclitaxel

Inheritance and Availability of High Grain Number Per Spike in Two Wheat Germplasm Lines

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Journal of Integrative Agriculture 2012年第9期11卷 1409-1416页

作者： CHEN Dan ZHANG Jin-peng wang jian-sheng YANG Xin-ming LIU Wei-hua GAQ Ai-nong LI Xiu-quan LI Li-hui National Key Facility for Crop Gene Resources and Genetic Improvement/Institute of Crop Sciences Chinese Academy of Agricultural Sciences Beijing 100081 P.R.China Hybrid Rapeseed Research Center of Shaanxi Province/Shaanxi Rapeseed Branch of National Oil Crops Genetic Improvement Center Dali 715105 P.R.China

Grain number per spike （GNPS） is a major factor in wheat yield breeding. The development of high GNPS germplasm is widely emphasized in wheat-yield breeding. This paper reported two high GNPS wheat germplasm lines, Pubing 3228 and Pubing 3504, which had a stable and wide adaptability to different ecological regions. By exploring a nested cross design with reciprocals using Pubing 3228 or Pubing 3504 as a common parent and investigating the GNPS phenotypes of F1 hybrids in 2007-2008 and F2 populations in 2008-2009 of different cross combinations, the narrow-sense GNPS heritability was up to 49.58 and 52.23%, respectively. Genetic model analysis predictions suggested that GNPS in Pubing 3228 and Pubing 3504 was mainly controlled by additive genetic effects. Correlation analysis results between GNPS and 1 000- kernel weight （TKW） of F2 populations showed that TKW was not influenced with the increase of GNPS. The good coordination among three yield components of spike number per plant （SNPP）, GNPS, and TKW in the F2 segregating population implied that selection of good candidate individuals in breeding programs would be relatively straightforward. Overall, our results indicated that Pubing 3228 and Pubing 3504 are two potential germplasm lines for yield improvement of GNPS in pedigree selection of wheat breeding.

关键词： wheat high grain number per spike inheritance yield breeding

Isolation and Complete Nucleotide Sequence of the Measles Virus IMB-1 Strain in China

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Virologica Sinica 2010年第6期25卷 381-389页

作者： Shao-hui MA Li-chun wang jian-sheng LIU Hai-jing SHI Long-ding LIU Qi-han LI Institute of Medical Biology Chinese Academy of Medical Sciences and Peking Union Medical College Kunming 650118 China

The complete nucleotide sequence of the measles virus strain IMB-1,which was isolated in China,was *** in other measles viruses,its genome is 15,894 nucleotides in length and encodes six *** full-length nucleotide sequence of the IMB-1 isolate differed from vaccine strains (including wild-type Edmonston strain) by 4%-5% at the nucleotide sequence *** isolate has amino acid variations over the full genome,including in the hemagglutinin and fusion *** report is the first to describe the full-length genome of a genotype H1 strain and provide an overview of the diversity of genetic characteristics of a circulating measles virus.

关键词： Complete nucleotide sequence Genotype H1 Measles virus (MV)

不锈钢1Cr18Ni9Ti电火花沉积层的组织和成分

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金属热处理 2007年第2期32卷 57-59页

作者：王建升北京科技大学腐蚀与防护中心北京100083

以YG8合金为电极,1Cr18N i9Ti不锈钢为基体,研究了电火花沉积工艺对沉积层组织结构及沉积层性能的影响。研究结果表明,电火花沉积功率和沉积时间对电火花沉积层的厚度和硬度有一定的影响;沉积工艺影响沉积层内合金元素的分布,导致沉积... 详细信息

以YG8合金为电极,1Cr18N i9Ti不锈钢为基体,研究了电火花沉积工艺对沉积层组织结构及沉积层性能的影响。研究结果表明,电火花沉积功率和沉积时间对电火花沉积层的厚度和硬度有一定的影响;沉积工艺影响沉积层内合金元素的分布,导致沉积层内的碳化物有明显的差异。当小功率短时间沉积时,白亮层的物相主要为Cr0.19Fe0.07N i0.01、WC1-x、CoCx和少量的N i-Cr-Fe;使用大功率长时间沉积时,白亮层的物相主要为(Cr Fe)7C3、CrC、Co3W3C和N i-Cr-Fe。

关键词：电火花沉积 YG8沉积层组织和成分 1Cr18Ni9Ti钢

熵受限在纳流控生物分子分离系统中的应用(英文)

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光学精密工程 2009年第6期17卷 1403-1408页

作者： LI Zi- rui LIU Gui- rong HAN Jongyoon wang jian-sheng CHEN Yu-zong . The Singapore-MIT Alliance (SMA) Singapore 117576 Department of Mechanical Engineering National University of Singapore Singapore 117576 Massachusetts Institute of Technology Cambridge Massachusetts 02139 USA Department of Physics National University of Singapore Singapore 117542 Department of Pharmacy National University of Singapore Singapore 117543

提出了生物分子在深度周期性变化纳米流控通道中输运的理论模型。该系统利用不同大小的非各向同性粒子处在两个平面组成的狭小空间时转动自由度受限制程度(熵受限)的不同来实现带电粒子的分离。基于一维简化模型,建立了有效迁移率与通... 详细信息

提出了生物分子在深度周期性变化纳米流控通道中输运的理论模型。该系统利用不同大小的非各向同性粒子处在两个平面组成的狭小空间时转动自由度受限制程度(熵受限)的不同来实现带电粒子的分离。基于一维简化模型,建立了有效迁移率与通道尺寸、分子大小以及外电场强度的关系的解析解,用于表明这些因素如何决定分子分离的效果。算例表明对于50,150和300bp的DNA片段,在低电场强度下,迁移率误差值在5 %以下。该简化模型可用于分析和优化实际的纳滤分离系统,而无需做复杂的数值模拟,省去了大量的物理实验过程。

关键词： DNA 电泳分离技术纳流系统熵受限生物分子分离生物芯片

Fourier transform infrared spectroscopy of gallbladder carcinoma cell line

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Hepatobiliary & Pancreatic Diseases International 2009年第1期8卷 75-78页

作者： Du, Jun-Kai Shi, Jing-Sen Sun, Xue-Jun wang, jian-sheng Xu, Yi-Zhuang Wu, Jin-Guang Zhang, Yuan-Fu Weng, Shi-Fu Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Dept Gen Surg Xian 710061 Peoples R China Peking Univ Coll Chem & Mol Engn Beijing 100871 Peoples R China

BACKGROUND: Fourier transform infrared (FT-IR) spectroscopy is a physical method applied to the study of cellular changes at the molecular level in various normal and diseased human tissues, including cancer. This study was undertaken to establish a cellular basis for the diagnosis of carcinoma tissue, using FT-IR spectroscopy to study a carcinoma cell line and investigating the specific spectral features of the cell line. METHODS: The FT-IR spectra of cultured gallbladder carcinoma cells (GBC-SD) smeared on a BaF(2) window were measured with a Nicolet Magna750-II FT-IR spectrometer. A comparative study was subsequently carried out between the spectra of cultured gallbladder carcinoma cells and those of corresponding carcinoma tissue. RESULTS: Several infrared spectral features were obtained, and the results suggest that the spectral features of the carcinoma cell line reflect those of carcinoma tissue, though the latter are more complex, probably due to the intrinsic complexity of the tissue. CONCLUSION: The diagnosis of carcinoma tissue by FTIR spectroscopy has a sufficient cellular basis.

关键词： spectroscopy, Fourier transform infrared gallbladder neoplasm cell line

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喀土穆炼油厂焦化装置防腐蚀研究及对策

腐蚀科学与防护技术 2009年第4期21卷 423-425页

作者：王健生中国石油广西石化钦州535008 苏丹喀土穆炼油厂

针对苏丹喀土穆炼油厂焦化装置的腐蚀现状,通过测厚、腐蚀挂片、腐蚀监测和腐蚀产物的分析化验等手段对设备的腐蚀原因及其腐蚀机理进行了分析,提出了防腐工艺、材料升级、腐蚀监测和防腐管理等防腐蚀措施.

关键词：焦化分馏电脱盐腐蚀分析对策