Isolation and Complete Nucleotide Sequence of the Measles Virus IMB-1 Strain in China
Isolation and Complete Nucleotide Sequence of the Measles Virus IMB-1 Strain in China作者机构:Institute of Medical Biology Chinese Academy of Medical Sciences and Peking Union Medical College Kunming 650118 China
出 版 物:《Virologica Sinica》 (中国病毒学(英文版))
年 卷 期:2010年第25卷第6期
页 面:381-389页
核心收录:
学科分类:0710[理学-生物学] 090603[农学-临床兽医学] 1007[医学-药学(可授医学、理学学位)] 090601[农学-基础兽医学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 09[农学] 0906[农学-兽医学]
基 金:Public Benefit Grant of Ministry of Health P.R China (200802035) Basic Research Foundation(General Program) of Yunnan Province (2008CD153)
主 题:Complete nucleotide sequence Genotype H1 Measles virus (MV)
摘 要:The complete nucleotide sequence of the measles virus strain IMB-1,which was isolated in China,was *** in other measles viruses,its genome is 15,894 nucleotides in length and encodes six *** full-length nucleotide sequence of the IMB-1 isolate differed from vaccine strains (including wild-type Edmonston strain) by 4%-5% at the nucleotide sequence *** isolate has amino acid variations over the full genome,including in the hemagglutinin and fusion *** report is the first to describe the full-length genome of a genotype H1 strain and provide an overview of the diversity of genetic characteristics of a circulating measles virus.