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Bilateral adrenal histoplasmosis in a Malaysian tertiary hospital:Report of four cases

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Asian Pacific Journal of Tropical Medicine 2024年第2期17卷 91-94页

作者： Kang WH Norasyikin abdul wahab Department of Medicine Faculty of Medicine and Health SciencesUniversity Tunku Abdul RahmanMalaysia Department of Medicine Pusat Perubatan Universiti KebangsaanMalaysia

Rationale:Adrenal histoplasmosis can present as bilateral adrenal enlargement with constitutional symptoms and/or adrenal *** these patients are initially investigated as secondary adrenal metastases before eventually their diagnosis established by histopathological examination of the adrenal *** concerns:We report 4 cases of patients aged 55-78 who presented with hypocortisolism and bilateral adrenal ***:Bilateral adrenal ***:Three patients received antifungal treatment for at least one year while 1 patient passed away before the initiation of antifungal ***:Two patients’adrenal function recovered not requiring any steroid replacement,while 1 patient still requires long-term steroid ***:Adrenal histoplasmosis should be excluded in patients from endemic areas presenting with bilateral adrenal masses and adrenal *** patients have an exposure to bird droppings,bat guano or soil contaminated with histoplasmosis *** examination of biopsied adrenal tissues is still the gold standard investigation as serology and molecular diagnostic methods are still not widely available in most centers in Malaysia.

关键词： Adrenal histoplasmosis Histoplasmosis Bilateral adrenal masses

Stochastic Computing Convolutional Neural Network Architecture Reinvented for Highly Efficient Artificial Intelligence Workload on Field-Programmable Gate Array

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Research 2024年第2期2024卷 55-79页

作者： Yang Yang Lee Zaini abdul Halim Mohd Nadhir Ab wahab Tarik Adnan Almohamad School of Electrical and Electronic Engineering Universiti Sains MalaysiaNibong Tebal 14300 Penang Malaysia School of Computer Sciences Universiti Sains MalaysiaGelugor11800 PenangMalaysia Electrical-Electronics Engineering Department Faculty of EngineeringKarabuk University78050 KarabukTurkiye

Stochastic computing(SC)has a substantial amount of study on application-specific integrated circuit(ASIC)design for artificial intelligence(AI)edge computing,especially the convolutional neural network(CNN)***,SC has little to no optimization on field-programmable gate array(FPGA).Scaling up the ASIC logic without FPGA-oriented designs is inefficient,while aggregating thousands of bitstreams is still challenging in the conventional *** research has reinvented several FPGA-efficient 8-bit SC CNN computing architectures,i.e.,SC multiplexer multiply-accumulate,multiply-accumulate function generator,and binary rectified linear unit,and successfully scaled and implemented a fully parallel CNN model on Kintex7 *** proposed SC hardware only compromises 0.14%accuracy compared to binary computing on the handwriting Modified National Institute of Standards and Technology classification task and achieved at least 99.72%energy saving per image feedforward and 31?more data throughput than modern *** to SC,early decision termination pushed the performance baseline exponentially with minimum accuracy loss,making SC CNN extremely lucrative for AI edge computing but limited to classification *** SC's inherent noise heavily penalizes CNN regression performance,rendering SC unsuitable for regression tasks.

关键词： hardware Highly rendering

Enhancing IoT Data Security with Lightweight Blockchain and Okamoto Uchiyama Homomorphic Encryption

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1731-1748页

作者： Mohanad A.Mohammed Hala B.abdul wahab Computer Science Department The University of TechnologyBaghdadIraq

Blockchain technology has garnered significant attention from global organizations and researchers due to its potential as a solution for centralized system ***,the Internet of Things(IoT)has revolutionized the Fourth Industrial Revolution by enabling interconnected devices to offer innovative services,ultimately enhancing human *** paper presents a new approach utilizing lightweight blockchain technology,effectively reducing the computational burden typically associated with conventional blockchain *** integrating this lightweight blockchain with IoT systems,substantial reductions in implementation time and computational complexity can be ***,the paper proposes the utilization of the Okamoto Uchiyama encryption algorithm,renowned for its homomorphic characteristics,to reinforce the privacy and security of IoT-generated *** integration of homomorphic encryption and blockchain technology establishes a secure and decentralized platformfor storing and analyzing sensitive data of the supply chain *** platformfacilitates the development of some business models and empowers decentralized applications to perform computations on encrypted data while maintaining data *** results validate the robust security of the proposed system,comparable to standard blockchain implementations,leveraging the distinctive homomorphic attributes of the Okamoto Uchiyama algorithm and the lightweight blockchain paradigm.

关键词： Blockchain IoT integration of IoT and blockchain consensus algorithm Okamoto Uchiyama homomorphic encryption lightweight blockchain

Adaptable and Dynamic Access Control Decision-Enforcement Approach Based on Multilayer Hybrid Deep Learning Techniques in BYOD Environment

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Computers, Materials & Continua 2024年第9期80卷 4663-4686页

作者： Aljuaid Turkea Ayedh M Ainuddin Wahid abdul wahab Mohd Yamani Idna Idris Faculty of Computer Science and Information Technology Universiti MalayaKuala Lumpur50603Malaysia Faculty of Computer Science and Information Technology Shaqra UniversityShaqra11961Saudi Arabia Center for Mobile Cloud Computing Faculty of Computer Science and Information TechnologyUniversiti MalayaKuala Lumpur50603Malaysia

Organizations are adopting the Bring Your Own Device(BYOD)concept to enhance productivity and reduce ***,this trend introduces security challenges,such as unauthorized *** access control systems,such as Attribute-Based Access Control(ABAC)and Role-Based Access Control(RBAC),are limited in their ability to enforce access decisions due to the variability and dynamism of attributes related to users and *** paper proposes a method for enforcing access decisions that is adaptable and dynamic,based on multilayer hybrid deep learning techniques,particularly the Tabular Deep Neural Network Tabular DNN *** technique transforms all input attributes in an access request into a binary classification(allow or deny)using multiple layers,ensuring accurate and efficient access *** proposed solution was evaluated using the Kaggle Amazon access control policy dataset and demonstrated its effectiveness by achieving a 94%accuracy ***,the proposed solution enhances the implementation of access decisions based on a variety of resource and user attributes while ensuring privacy through indirect communication with the Policy Administration Point(PAP).This solution significantly improves the flexibility of access control systems,making themmore dynamic and adaptable to the evolving needs ofmodern ***,it offers a scalable approach to manage the complexities associated with the BYOD environment,providing a robust framework for secure and efficient access management.

关键词： BYOD security access control access control decision-enforcement deep learning neural network techniques TabularDNN multilayer dynamic adaptable flexibility bottlenecks performance policy conflict

基于混合消能减震技术非对称双塔连体结构抗震性能研究

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振动与冲击 2024年第6期43卷 288-300页

作者：蔡正潘文周强 Ghafar wahab abdul 杨静昆明理工大学建筑工程学院昆明650599 云南省抗震工程技术研究中心昆明650599

以某非对称双塔连体超高层结构为研究对象,选取与建筑所在场地相匹配的地震波作为激励,通过对结构进行非线性动力时程分析,研究混合消能减震连体结构在各烈度地震作用下的消能减震效果,探讨了屈曲约束支撑(buckling-restrained brace, B... 详细信息

以某非对称双塔连体超高层结构为研究对象,选取与建筑所在场地相匹配的地震波作为激励,通过对结构进行非线性动力时程分析,研究混合消能减震连体结构在各烈度地震作用下的消能减震效果,探讨了屈曲约束支撑(buckling-restrained brace, BRB)与黏滞阻尼悬臂桁架的位置变化对结构抗震性能的影响,同时对结构进行了全面的抗震性能评估。研究结果表明:在连体结构中、上部的加强层中布设阻尼器时,结构具有更佳的减震效果;在不同水准地震作用下,BRB与黏滞阻尼悬臂桁架耗能阶段不同且具有不同的耗能效率,混合消能减震技术可以综合不同类型阻尼器的优势作用,使连体结构具有更全面的抗震性能。在控制变形方面,其能够降低连体结构的扭转效应和层间位移角;在构件耗能方面,其减轻了主体构件进入塑性的程度,降低了结构主要受力构件的应力水平。将为混合消能减震技术在连体超高层结构中的进一步研究和应用提供借鉴。

关键词：连体结构混合减震时程分析耗能机制抗震性能

Multi-species probiotics enhance survival,growth,intestinal microbiota and disease resistance of rohu(Labeo rohita)larvae

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Water Biology and Security 2024年第1期3卷 71-79页

作者： Zannatul Ferdous md Kabir Hossain md Hadiuzzaman SMRafiquzzaman KM abdul Halim Tanvir Rahman md Ali Reza Faruk Zulhisyam abdul Kari md Shahjahan Laboratory of Fish Ecophysiology Department of Fisheries ManagementBangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Aquaculture Bangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Fisheries Matshoy BhabanDhakaBangladesh Department of Fisheries Biology&Aquatic Environment Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh Department of Agricultural Sciences Faculty of Agro-Based IndustryUniversiti Malaysia KelantanJeli Campus17600JeliKelantanMalaysia

Multi-strain probiotics provide the most dependable approaches to improve health,immune response,and disease resistance in farmed *** the present study,we examined the effects of multi-species probiotics on the survival,growth,immune response,and disease resistance of rohu(Labeo rohita)*** hatched larvae from the day of first feeding(average weight of 0.003 g)were reared with multi-species probiotics having a combination of Bacillus subtilis(109 colony forming units(cfu)/mL)and Lactobacillus spp.(Lactobacillus plantarum,Lactobacillus buchneri-1011 cfu/mL)in water containing doses of 0(control-C),0.5 mL/L(treatment 1-T1),and 1.0 mL/L(treatment 2-T2)in triplicates for 90 *** the experiment,a challenge test was performed to assess the fish's resistance to pathogenic Aeromonas *** higher survival was recorded in larvae of treated groups(87%in T2 and 79%in T1)compared to the control(62%).Significantly higher growth performance(weight gain and specific growth rate—SGR)was shown by the probiotic-treated larval groups compared to the *** supplementation resulted in significantly higher counts of total viable colony(TVC)and lactic acid bacteria(LAB)in the *** immunological parameters(mucosal fold fattening,goblet cell abundance,expansion of lamina propria and enterocytes)of the gut were significantly better in probiotic-treated *** liver of treated fish showed irregular shape nuclei turning into regular shape and reducing spaces between the hepatic ***-treated fish had the highest post-challenge survival rate(90%)against *** *** erythrocytes of challenged fish treated with probiotics had significantly lower frequencies of various nuclear and cellular *** findings suggest that multi-species probiotic supplements could improve the survival,growth,health status,and immune response of rohu in the early stages of its development.

关键词： Aquaculture Disease resistance Immunity Labeo rohita Probiotics

Tuberculosis-diabetes comorbidities: Mechanistic insights for clinical considerations and treatment challenges

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World Journal of Diabetes 2024年第5期15卷 853-866页

作者： md.abdul Alim Al-Bari Nicholas Peake Nabil Eid Department of Pharmacy University of RajshahiRajshahi 6205Bangladesh Biosciences and Chemistry and Biomolecular Research Centre Sheffield Hallam UniversitySheffield S11WBUnited Kingdom Department of Anatomy Division of Human BiologySchool of MedicineInternational Medical UniversityKuala Lumpur 57000Malaysia

Tuberculosis(TB)remains a leading cause of death among infectious diseases,particularly in poor *** infections,multidrug-resistant and ex-tensively drug-resistant TB strains,as well as the coexistence of chronic illnesses such as diabetes mellitus(DM)greatly aggravate TB morbidity and ***[particularly type 2 DM(T2DM)]and TB have converged making their control even more *** contemporary global epidemics,TB-DM behaves like a syndemic,a synergistic confluence of two highly prevalent diseases.T2DM is a risk factor for developing more severe forms of multi-drug resistant-TB and TB recurrence after preventive *** a bidirectional relationship exists between TB and DM,it is necessary to concurrently treat both,and promote recommendations for the joint management of both *** are also some drug-drug interactions resulting in adverse treatment outcomes in TB-DM patients including treatment failure,and *** addition,autophagy may play a role in these ***,the TB-DM comorbidities present several health challenges,requiring a focus on multidisciplinary collaboration and integrated strategies,to effectively deal with this double *** effectively manage the comorbidity,further screening in affected countries,more suitable drugs,and better treatment strategies are required.

关键词： Diabetes mellitus Tuberculosis Coinfections Comorbidity Drug-drug interactions Autophagy Treatment challenges

Graphene oxide-coated microbottle resonators for relative humidity sensing

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Optoelectronics Letters 2024年第7期20卷 400-405页

作者： Huda Adnan Zain Malathy Batumalay md Ashadi md Johari Hazli Rafis abdul Rahim Sulaiman Wadi Harun Department of Electrical Engineering Faculty of EngineeringUniversity of MalayaKuala Lumpur 50603Malaysia Faculty of Data Science and Information Technology INTI International UniversityNilai 71800Malaysia1 Faculty of Electrical and Electronic Engineering Technology Universiti Teknikal Malaysia MelakaMelaka 76100Malaysia Faculty of Electronic and Computer Engineering Universiti Teknikal Malaysia MelakaMelaka 76100Malaysia

Graphene oxide(GO)is a 2D coating material used to improve fiber optics sensors’response to relative *** resonators(MBRs)have garnered more attention as sensing media *** MBR with a 190μm diameter was coated with ***,tapered fiber light coupling was used to investigate the relative humidity sensing performance in the range of 35—70%RH at 25℃.The MBR showed a higher Q factor before and after GO *** sensitivity of 0.115 dB/%RH was recorded with the 190μm GO-coated MBR sample compared to a sensitivity of 0.022 dB/%RH for the uncoated MBR *** results show that the MBR can be used in fiber optic sensing applications for environmental sensing.

关键词： humidity oxide bottle

Zoonotic human liver flukes,a type 1 biocarcinogen,in freshwater fishes:genetic analysis and confirmation of molluscan vectors and reservoir hosts in Bangladesh

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Infectious Diseases of Poverty 2024年第3期13卷 73-88页

作者： Sharmin Shahid Labony md.abdul Alim Muhammad Mehedi Hasan md.Shahadat Hossain Sharmin Akter Joydeep Paul Thahsin Farjana md.Haydar Ali Mohammad Zahangir Alam Takeshi Hatta Hayato Kawada Keiko Mizutani Naotoshi Tsuji null Anisuzzaman Department of Parasitology Faculty of Veterinary ScienceBangladesh Agricultural UniversityMymensingh 2202Bangladesh Department of Fisheries Technology Faculty of FisheriesBangladesh Agricultural UniversityMymensingh 2202Bangladesh Department of Biotechnology School of Life Sciences&BiotechnologyAdamas UniversityBarasat-Barrackpore RdJagannathpurKolkataWest Bengal 700126India Department of Pathology and Parasitology Hajee Mohammad Danesh Science and Technology UniversityDinajpur 5200Bangladesh Department of Parasitology and Tropical Medicine Kitasato University School of Medicine1-15-1 KitasatoMinamiSagamiharaKanagawa 252-0374Japan Department of Molecular and Cellular Parasitology Kitasato University Graduate School of Medical Sciences1-15-1 KitasatoMinamiSagamiharaKanagawa 252-0373Japan

Background Opisthorchiid flukes,particularly Opisthorchis viverrini,Opisthorchis felineus,Clonorchis sinensis,and Metorchis *** the most common fish-borne zoonotic human liver flukes(hLFs).Liver fluke infections are more prevalent in resource-deprived and underprivileged *** herein estimated the prevalence of the metacercariae(MC)of major hLFs in common large freshwater fishes(lFWF)marketed for human consumption from some selected areas of Bangladesh along with detection of their molluscan vectors and *** The current status of fish-borne zoonotic hLF infections in lFWF was investigated along with their molluscan vectors and mammalian reservoir hosts in Mymensingh and Kishoreganj in Bangladesh from July 2018-June 2022 using conventional and multiple molecular techniques,such as PCR,PCR-restriction fragment length polymorphism(RFLP),sequencing,and bioinformatic *** infection rate of fishes was analyzed using the Z-test and the loads of MC were compared using the chi-squared(χ^(2))*** The MC of ***,Opisthorchis spp.,and Metorchis *** detected in 11 species of common and popular *** lFWF,the estimated prevalence was 18.7%and the mean load was 137.4±149.8 MC per 100 g of *** prevalence was the highest(P0.05)distributed between the head and body of *** infection rate was slightly higher in cultured(19.6%)*** MC of ***,***,***,and Metorchis orientalis in fishes were confirmed using PCR,PCR-RFLP and *** cercariae of opisthorchiid(Pleurolophocercus cercariae)flukes were only recovered from Bithynia spp.(3.9%,42 out of 1089).The ova of hLFs from dogs(4.3%,5 out of 116)and cats(6.0%,6 out of 100),and adult flukes(***)from ducks(41.1%113 out of 275)were *** The MC of

关键词： Human liver fluke Freshwater fish Molluscan vector Reservoir host Bangladesh