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Heparin-induced thrombocytopenia in solid organ transplant recipients: The current scientific knowledge

World Journal of Transplantation 2016年第1期6卷 165-173页

作者： volker assfalg Norbert Hüser Department of Surgery Klinikum rechts der Isar der Technischen Universit?t München

Exposure to heparin is associated with a high incidence of immunization against platelet factor 4(PF4)/heparin complexes. A subgroup of immunized patients is at risk of developing heparin-induced thrombocytopenia(HIT), an immune mediated prothrombotic adverse drug effect. Transplant recipients are frequently exposed to heparin either due to the underlying end-stage disease, which leads to listing and transplantation or during the transplant procedure and the perioperative period. To review the current scientific knowledge on antiheparin/PF4 antibodies and HIT in transplant recipients a systematic Pub Med literature search on articles in English language was performed. The definition of HIT is inconsistent amongst the publications. Overall, six studies and 15 case reports have been published on HIT before or after heart, liver, kidney, and lung transplantation, respectively. The frequency of seroconversion for anti-PF4/heparin antibodies ranged between 1.9% and 57.9%. However, different methods to detect anti-PF4/heparin antibodies were applied. In none of the studies HIT-associated thromboembolic events or fatalities were observed. More importantly, in patients with a history of HIT, reexposure to heparin during transplantation was not associated with thrombotic complications. Taken together, the overall incidence of HIT after solid organ transplantation seems to be very low. However, according to the current knowledge, cardiac transplant recipients may have the highest risk to develop HIT. Different alternative suggestions for heparin-free anticoagulation have been reported for recipients with suspected HIT albeit no official recommendations on management have been published for this special collective so far.

关键词： Heparin-induced thrombocytopenia Heparininduced thrombocytopenia Heparin Organ Transplantation

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Harmonic maps with torsion

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Science China Mathematics 2021年第7期64卷 1373-1390页

作者： volker Branding Faculty of Mathematics University of ViennaVienna 1090Austria

In this article we introduce a natural extension of the well-studied equation for harmonic maps between Riemannian manifolds by assuming that the target manifold is equipped with a connection that is metric but has non-vanishing *** connections have already been classified in the work of Cartan(1924).The maps under consideration do not arise as critical points of an energy functional leading to interesting mathematical *** will perform a first mathematical analysis of these maps which we will call harmonic maps with torsion.

关键词： harmonic maps with torsion metric torsion regularity of weak solutions

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RELATIVE ENTROPY AND COMPRESSIBLE POTENTIAL FLOW

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Acta Mathematica Scientia 2015年第4期35卷 763-776页

作者： volker ELLING Department of Mathematics East Hall University of Michigan

Compressible （full） potential flow is expressed as an equivalent first-order system of conservation laws for density ρ and velocity v. Energy E is shown to be the only nontrivial entropy for that system in multiple space dimensions, and it is strictly convex in ρ, v if and only if ｜v｜〈 c. For motivation some simple variations on the relative entropy theme of Dafer- mos/DiPerna are given, for example that smooth regions of weak entropy solutions shrink at finite speed, and that smooth solutions force solutions of singular entropy-compatible per- turbations to converge to them. We conjecture that entropy weak solutions of compressible potential flow are unique, in contrast to the known counterexamples for the Euler equations.

关键词： potential flow entropy relative entropy shock

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THE CARBUNCLE PHENOMENON IS INCURABLE

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Acta Mathematica Scientia 2009年第6期29卷 1647-1656页

作者： volker Elling Department of Mathematics University of Michigan MI4810-1043 USA

Numerical approximations of multi-dimensional shock waves sometimes ex- hibit an instability called the carbuncle phenomenon. Techniques for suppressing carbuncles are trial-and-error and lack in reliability and generality, partly because theoretical knowledge about carbuncles is equally unsatisfactory. It is not known which numerical schemes are affected in which circumstances, what causes carbuncles to appear and whether carbuncles are purely mimerical artifacts or rather features of a continuum equation or model. This article presents evidence towards the latter： we propose that carbuncles are a special class of entropy solutions which can be physically correct in some circumstances. Using ＂filaments＂, we trigger a single carbuncle in a new and more reliable way, and compute the structure in detail in similarity coordinates. We argue that carbuncles can, in some circumstances, be valid vanishing viscosity limits. Trying to suppress them is making a physical assumption that may be false.

关键词： shock Euler equation carbuncle entropy solution

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HOLDER CONTINUITY AND DIFFERENTIABILITY ON CONVERGING SUBSEQUENCES

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Acta Mathematica Scientia 2012年第1期32卷 75-83页

作者： volker Elling Department of Mathematics University of Michigan

It is shown that an arbitrary function from D Rn to Rm will become C0,a-continuous in almost every x∈ D after restriction to a certain subset with limit pointx. For n 〉 m differentiability can be obtained. Example... 详细信息

关键词： Ho1der continuity Lipschitz continuity differentiability restriction weaksolution

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Direct molecular-level near-field plasmon and temperature assessment in a single plasmonic hotspot

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Light(Science & Applications) 2020年第1期9卷 1673-1685页

作者： Marie Richard-Lacroix volker Deckert Leibniz Institute of Photonic Technology(IPHT) Albert-Einstein-Strasse 9D-07745 JenaGermany Institute of Physical Chemistry and Abbe Center of Photonics University of JenaHelmholtzweg 4D-07743 JenaGermany

Tip-enhanced Raman spectroscopy(TERS)is currently widely recognized as an essential but still emergent technique for exploring the ***,our lack of comprehension of crucial parameters still limits its potential as a user-friendly analytical *** tip’s surface plasmon resonance,heating due to near-field temperature rise,and spatial resolution are undoubtedly three challenging experimental parameters to ***,they are also the most fundamentally relevant parameters to explore,because they ultimately influence the state of the investigated molecule and consequently the probed *** we propose a straightforward and purely experimental method to access quantitative information of the plasmon resonance and near-field temperature experienced exclusively by the molecules directly contributing to the TERS *** detailed near-field optical response,both at the molecular level and as a function of time,is evaluated using standard TERS experimental equipment by simultaneously probing the Stokes and anti-Stokes spectral ***-assembled 16-mercaptohexadodecanoic acid monolayers covalently bond to an ultra-flat gold surface were used as a *** of blinking lines in the spectra also provides crucial information on the lateral resolution and indication of atomic-scale thermally induced morphological changes of the tip during the *** study provides access to unprecedented molecular-level information on physical parameters that crucially affect experiments under TERS *** study thereby improves the usability of TERS in day-to-day *** obtained information is of central importance for any experimental plasmonic investigation and for the application of TERS in the field of nanoscale thermometry.

关键词： straight purely thereby

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The N* physics program at Jefferson Lab

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Chinese Physics C 2009年第12期33卷 1043-1050页

作者： volker D. Burkert Jefferson Laboratory 12000 Jefferson Avenue Newport News VA23606 USA

Recent measurements of nucleon resonance transition form factors with CLAS at Jefferson Lab are discussed. The new data confirm the assertion of the symmetric constituent quark model of the Roper as the first radial excitation of the nucleon. The data on high Q2 nπ＋ production better constrain the branching ratios liNK and [3Nn. For the first time, the longitudinal transition amplitude to the S11（1535） was extracted from the nπ＋ data. Also, new results on the transition amplitudes for the D13（1520） resonance are presented showing a rapid transition from helicity 3/2 dominance seen at the real photon point to helicty 1/2 dominance at higher Q2. I also discuss the status of the search for new excited nucleon states.

关键词： nucleon resonances transition form factors NA transition Roper magnetic dipole

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The European Carbon dioxide Capture and Storage Laboratory Infrastructure(ECCSEL)

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Green Energy & Environment 2016年第3期1卷 180-194页

作者： Sverre Quale volker Rohling Department of Energy and Process Engineering Norwegian University of Science and Technology(NTNU)

The transition to a non-emitting energy mix for power generation will take decades. This transition will need to be sustainable, *** affordable. Fossil fuels which are abundant have an important role to play in this respect, provided that Carbon Capture and Storage(CCS) is progressively implemented. CCS is the only way to reduce emissions from energy intensive ***, the need for upgraded and new CCS research facilities is widely recognised among stakeholders across Europe, as emphasised by the Zero Emissions Platform(ZEP) [1] and the European Energy Research Alliance on CCS(EERA-CCS) [2].The European Carbon Dioxide Capture and Storage Laboratory Infrastructure, ECCSEL, provides funders, operators and researchers with significant benefits by offering access to world-class research facilities that, in many cases, are unlikely for a single nation to support in *** implies creation of synergy and the avoidance of duplication as well as streamlining of funding for research *** offers open access to its advanced laboratories for talented scientists and visiting researchers to conduct cutting-edge *** the planning of ECCSEL, gap analyses were performed and CCS technologies have been reviewed to underpin and envisage the future experimental setup; 1) Making use of readily available facilities, 2) Modifying existing facilities, and 3) Planning and building entirely new advanced *** investments required for the first ten years(2015-2025) are expected to be in the range of €80-120 miilion. These investments show the current level of ambition, as proposed during the preparatory phase(2011-2014).Entering the implementation phase in 2015, 9 European countries signed Letter of Intent(LoI) to join a ECCSEL legal entity: France, United Kingdom, Netherlands, Italy, Spain, Poland, Greece, Norway and Switzerland(active observer). As the EU ERIC-regulation [3] would offer the most suitable legal framework for ECCSEL, th

关键词： CCS Carbon Dioxide Capture Transport and Storage CO2 Research Infrastructure Laboratory

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The Author Reply

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Hepatobiliary & Pancreatic Diseases International 2014年第3期13卷 555-556页

作者： volker Schmitz Department of General Visceral and Transplantation SurgeryCharite Campus VirchowBerlin 13353 Germany

I have read with interest the comment on our manuscript[1]on different outcomes following cava reconstruction in liver transplantation using either cava replacement or piggy-back *** its initial publication by Tsakis ... 详细信息

关键词： comment replacement probably anastomosis Surgery preservation Berlin superiority today veins

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Robustness analysis metrics for worldwide airport network：A comprehensive study

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Chinese Journal of Aeronautics 2017年第2期30卷 500-512页

作者： Sun Xiaoqian volker Gollnick Sebastian Wandelt School of Electronic and Information Engineering Beihang University 100083 Beijing China Beijing Key Laboratory for Network-based Cooperative A TM Beijing 100083 China Beijing Laboratory for General Aviation Technology Beijing 100083 China Institute of Air Transportation Systems German Aerospace Center Blohmstrasse 18 21079 Hamburg Germany

Robustness of transportation networks is one of the major challenges of the 21 st *** paper investigates the resilience of global air transportation from a complex network point of view,with focus on attacking strategies in the airport network,i.e.,to remove airports from the system and see what could affect the air traffic system from a passenger＇s ***,we identify commonalities and differences between several robustness measures and attacking strategies,proposing a novel notion of functional robustness：unaffected passengers with *** apply twelve attacking strategies to the worldwide airport network with three weights,and evaluate three robustness *** find that degree and Bonacich based attacks harm passenger weighted network *** evaluation is geared toward a unified view on air transportation network attack and serves as a foundation on how to develop effective mitigation strategies.

关键词： Air transportation systems resilience Airport network Attacking strategy Robustness measure

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