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Journal of Behavioral and Brain Science 2014年第9期4卷 402-411页

作者： Yul-Wan sung uk-su choi Seiji Ogawa Kansei Fukushi Research Institute Tohoku Fukushi University Sendai Japan Neuroscience Research Institute Gachon University Incheon Korea

Tasks with stimuli are often used for the examination of stimulus-related functional characteristics of brain areas. However, the task can affect the response to a stimulus. Repetition suppression is a phenomenon that can be used to probe neuronal properties using macroscale functional magnetic resonance imaging (fMRI). The use of repetition suppression as an investigative tool to assess functional characteristics warrants the investigation of the invariance of repetition suppression to a given task. In this study, we examined repetition suppression using images of faces during different tasks. We found that the task difference did not change the response patterns related to repetition suppression in high-level areas and the primary visual area while it changed amplitudes of fMRI response to the visual stimuli. The result suggests that the repetition-suppression phenomenon is robust compared with the amplitude of fMRI response, and functional characteristics can be examined using the repetition-suppression phenomenon even under the condition that fMRI response is varied by task difference.

关键词： Task Difference Repetition suppression FFA Central Stimulation Peripheral Stimulation fMRI Face Images

Location privacy protection of maritime mobile terminals

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Digital Communications and Networks 2022年第6期8卷 932-941页

作者： Xin su su Jiang Dongmin choi College of IOT Engineering Hohai UniversityChangzhou213022China Division of Undeclared Majors Chosun UniversityRepublic of Korea

Mobile Edge Computing(MEC)can support various high-reliability and low-delay applications in Maritime Networks(MNs).However,security risks in computing task offloading *** this study,the location privacy leakage risk of Maritime Mobile Terminals(MMTs)is quantified during task offloading and relevant Location Privacy Protection(LPP)schemes of MMT are considered under two kinds of task offloading *** single-MMT and single-time offloading scenario,a dynamic cache and spatial cloaking-based LPP(DS-CLP)algorithm is proposed;and under the multi-MMTs and multi-time offloading scenario,a pseudonym and alterable silent period-based LPP(PA-SLP)strategy is *** results show that the DS-CLP can save the response time and communication cost compared with traditional algorithms while protecting the MMT location ***,extending the alterable silent period,increasing the number of MMTs in the maritime area or improving the pseudonym update probability can enhance the LPP effect of MMTs in ***,the study results can be effectively applied to MNs with poor communication environments and relatively insufficient computing resources.

关键词： Location privacy protection Maritime network Mobile edge computing Task floading

Cross-Domain Bilateral Access Control on Blockchain-Cloud Based Data Trading System

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 671-688页

作者： Youngho Park su Jin Shin Sang uk Shin Electronics and Information Communications Research Center Pukyong National UniversityBusan48513Republic of Korea Department of Information Security Graduate SchoolPukyong National UniversityBusan48513Republic of Korea Division of Computer Engineering Pukyong National UniversityBusan48513Republic of Korea

Data trading enables data owners and data requesters to sell and purchase *** the emergence of blockchain technology,research on blockchain-based data trading systems is receiving a lot of ***,to reduce the on-chain storage cost,a novel paradigm of blockchain and cloud fusion has been widely considered as a promising data trading ***,the fact that data can be used for commercial purposes will encourage users and organizations from various fields to participate in the data *** the data marketplace,it is a challenge how to trade the data securely outsourced to the external cloud in a way that restricts access to the data only to authorized users across multiple *** this paper,we propose a cross-domain bilateral access control protocol for blockchain-cloud based data trading *** consider a system model that consists of domain authorities,data senders,data receivers,a blockchain layer,and a cloud *** proposed protocol enables access control and source identification of the outsourced data by leveraging identity-based cryptographic *** the proposed protocol,the outsourced data of the sender is encrypted under the target receiver’s identity,and the cloud provider performs policy-match verification on the authorization tags of the sender and receiver generated by the identity-based signature ***,data trading can be achieved only if the identities of the data sender and receiver simultaneously meet the policies specified by each *** demonstrate efficiency,we evaluate the performance of the proposed protocol and compare it with existing studies.

关键词： Bilateral access control blockchain data sharing policy-match

Synthesis of N-doped carbon quantumn dots as lubricant additive to enhance the tribological behavioor f MoS_(2)nanofluid

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Friction 2023年第3期11卷 441-459页

作者： Jiaqi HE Jianlin suN Junho choi Chenglong WANG Daoxin su School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China Department of Mechanical Engineering The University of TokyoTokyo 113-8656Japan

In this study,a novel lubricant additive nitrogen-doped carbon quantum dot(N-CQD)nanoparticle was prepared by the solvothermal *** synthesized spherical N-CQD nanoparticles in the diameter of about 10 nm had a graphene oxide(GO)-like structure with various oxygen(O)-and nitrogen(N)-containing functional *** N-CQDs were added to MoS_(2)nanofluid,and the tribological properties for steel/steel friction pairs were evaluated using a pin-on-disk ***-equilibrium molecular dynamics(NEMD)simulations for the friction system with MoS_(2)or MoS_(2)+N-CQD nanoparticles were also *** results showed that friction processes with MoS_(2)+N-CQD nanofluids were under the mixed lubrication *** MoS_(2)nanofluid containing 0.4 wt%N-CQDs could achieve 30.4%and 31.0%reduction in the friction coefficient and wear rate,respectively,compared to those without *** analyzing the worn surface topography and chemical compositions,the excellent lubrication performance resulted from the formation of tribochemistry-induced *** average thickness of tribofilm was about 13.9 nm,and it was composed of amorphous substances,ultrafine crystalline nanoparticles,and self-lubricating FeSO_(4)/Fe2(SO_(4))_(3).NEMD simulation results indicated the interaction between S atoms in MoS_(2)as well as these O-and N-containing functional groups in N-CQDs with steel surfaces enhanced the stability and strength of *** the metal surface was further protected from friction and wear.

关键词： carbon-based quantum dots(CQDs) lubricant nanofluid molecular dynamics(MD) tribofilm

Omnidirectional color wavelength tuning of stretchable chiral liquid crystal elastomers

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Light(Science & Applications) 2024年第6期13卷 1062-1074页

作者： Seungmin Nam Wontae Jung Jun Hyuk Shin su Seok choi Department of Electrical Engineering Pohang University of Science and Technology(POSTECH)PohangKorea

Wavelength-tunable structural colors using stimuli-responsive materials,such as chiral liquid crystals(CLCs),have attracted increasing attention owing to their high functionality in various tunable photonic ***,on-demand omnidirectional wavelength control is highly desirable from the perspective of wavelength-tuning ***,despite numerous previous research efforts on tunable CLC structural colors,only mono-directional wavelength tuning toward shorter wavelengths has been employed in most studies to *** this study,we report the ideally desired omnidirectional wavelength control toward longer and shorter wavelengths with significantly improved tunability over a broadband wavelength *** using areal expanding and contractive strain control of dielectric elastomer actuators(DEAs)with chiral liquid crystal elastomers(CLCEs),simultaneous and omnidirectional structural color-tuning control was *** breakthrough in omnidirectional wavelength control enhances the achievable tuning freedom and versatility,making it applicable to a broad range of high-functional photonic applications.

关键词： tuning tunable directional

Prostate-specific antigen density predicts favorable pathology and biochemical recurrence in patients with intermediate-risk prostate cancer

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Asian Journal of Andrology 2016年第3期18卷 480-484,I0012页

作者： Ho Won Kang Hae Do Jung Joo Yong Lee Jong Kyou Kwon Seong uk Jeh Kang su Cho Won Sik Ham Young Deuk choi Department of Urology Chungbuk National University College of Medicine Cheongju Korea Department of Urology Severance Hospital Urological Science InstituteYonsei University College of Medicine Seoul Korea Department of Urology. Inje university Haeundae Paik Hospital Busan Korea Department of Urology Gyeongsang National University School of Medicine Jinju Korea Department of Urology Gangnam Severance Hospital Urological Science Institute Yonsei University Uollege of Medicine Seoul Korea Robot and Minimal Invasive surgery Center Severance Hospital Yonsei University College of Medicine Seoul Korea.

This study was designed to identify clinical predictors of favorable pathology and biochemical recurrence （BCR） in patients with intermediate-risk prostate cancer （IRPCa）. Between 2006 and 2012, clinicopathological and oncological data from 203 consecutive men undergoing robot-assisted radical prostatectomy （RARP） for IRPCa were reviewed in a single-institutional retrospective study. Favorable pathology was defined as Gleason score 〈6 and organ-confined cancer as detected by surgical pathology. Logistic regression analysis was used to determine predictive variables of favorable pathology, and the Kaplan-Meier and multivariate Cox regression model were used to estimate BCR-free survival after RARP. Overall, 38 patients （18.7%） had favorable pathology after RARP. Lower quartile prostate-specific antigen density （PSAD） was associated with favorable pathology compared to the highest quartile PSAD after adjusting for preoperative PSA, clinical stage and biopsy Gleason score （odds ratio, 5.42; 95% confidence interval, 1.01-28.97; P = 0.048）. During a median 37.8 （interquartile range, 24.6-60.2） months of follow-up, 66 patients experienced BCR. There were significant differences with regard to BCR free survival by PSAD quartiles （log rank, P = 0.003）. Using a multivariable Cox proportion hazard model, PSAD was found to be an independent predictor of BCR in patients with IRPCa after RARP （hazard ratio, 4.641; 95% confidence interval, 1.109-19.417; P = 0.036）. The incorporation of the PSAD into risk assessments might provide additional prognostic information and identify some patients in whom active surveillance would be appropriate in patients with IRPCa.

关键词： biochemical recurrence prostatectomy prostate-specific antigen prostate-specific antigen density prostatic neoplasms

Fully tunable Fabry-Pérot cavity based on MEMS Sagnac loop reflector with ultra-low static power consumption

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Microsystems & Nanoengineering 2024年第4期10卷 355-365页

作者： Young Jae Park Man Jae Her Youngjae Jeong Dong Ju choi Dong uk Kim Min Gi Lim Myung Seok Hong Hyug su Kwon Kyoungsik Yu Sangyoon Han Department of Robotics and Mechatronics Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Republic of Korea School of Electrical Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Agency for Defense Development DaejeonRepublic of Korea

The Fabry-Pérot interferometer,a fundamental component in optoelectronic systems,offers interesting applications such as sensors,lasers,and *** this work,we show a tunable Fabry-Pérot cavity consisting of tunable Sagnac loop reflectors(SLRs)and phase shifters based on electrostatic microelectromechanical(MEMS)*** fabrication process of the device is compatible with the standard wafer-level silicon photonics fabrication *** electrostatic actuation mechanism provides well-balanced,scalable pathways for efficient tuning *** extinction ratio of the continuously tunable SLRs’reflectivity is larger than 20 *** 2πphase shifting is achieved,and response times of all the components are less than 25μ*** actuators have extremely low static power,measuring under 20 fW and the energy needed for tuning is both below 20 pJ.

关键词： tunable tuning interferometer

T cell epitopes in SARS-CoV-2 proteins are substantially conserved in the Omicron variant

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Cellular & Molecular Immunology 2022年第3期19卷 447-448页

作者： Seong Jin choi Dong-uk Kim Ji Yun Noh Sangwoo Kim su-Hyung Park Hye Won Jeong Eui-Cheol Shin Division of Infectious Disease Department of Internal MedicineSeoul National University HospitalSeoulRepublic of Korea Graduate School of Medical Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea Division of Infectious Diseases Department of Internal MedicineKorea University College of MedicineSeoulRepublic of Korea Department of Biomedical Systems Informatics Graduate School of Medical ScienceBrain Korea 21 ProjectYonsei University College of MedicineSeoulRepublic of Korea Department of Internal Medicine Chungbuk National University College of MedicineCheongjuRepublic of Korea The Center for Viral Immunology Korea Virus Research InstituteInstitute for Basic Science(IBS)DaejeonRepublic of Korea

In November 2021,the Omicron variant(B.1.1.529)emerged and was designated a variant of concern(VOC)by the World Health ***,Omicron was reported to extensively escape neutralizing antibodies elicited by COVID-19 vaccination or natural infection[1,2,3].However,whether Omicron evades the T cell immunity elicited by COVID-19 vaccination or natural infection remains to be *** address this issue,we analyzed the amino acid sequences of T cell epitopes identified from the original SARS-CoV-2 strain(Wuhan-Hu-1)in the Omicron variant(hCoV-19/South Africa/CERI-KRISP-K032284/2021).

关键词： neutral conserved elucidated

Glycan targeting nanoparticle for photodynamic immunotherapy of melanoma

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Acta Pharmaceutica Sinica B 2023年第5期13卷 1903-1918页

作者： Yonghyun choi Wooic Son Youngpin Han Jayoung Chae Chul-su Yang Jonghoon choi School of Integrative Engineering Chung-Ang UniversitySeoul 06974Republic of Korea Department of Molecular&Life Science Hanyang UniversityAnsan 15588Republic of Korea Center for Bionano Intelligence Education and Research Hanyang UniversityAnsan 15588Republic of Korea

Interaction between tumour cells and macrophages enables cancer cells to evade immune detection and clearance by interfering with macrophage *** anti-phagocytic signals regulated by anti-phagocytic proteins are termed"don't eat me"signals;these signals include sialic acidbinding immunoglobulin-type lectin-10(Siglec-10)and the recently revealed CD24 immune checkpoint(ICP).In this study,we demonstrate that targeting a specific glycan on CD24 exhibits the potential to inhibit *** nigra agglutinin(SNA),a sialic acid-binding lectin,was employed to block CD24 and to enhance phagocytosis in melanoma *** addition,we prepared SNA-conjugated hollow gold-iron oxide nanoparticles for photothermal therapy of *** findings show that the combination treatment of SNA-conjugated photothermal nanoparticles and near-infrared exposure successfully augments tumour cell phagocytosis both in vitro and in vivo models.

关键词： Immunotherapy Macrophages Phagocytosis Lectin Melanoma cancer Photothermal nanoparticles Immune checkpoint Glycan

Uncertainty analysis of flow rate measurement for multiphase flow using CFD

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Acta Mechanica Sinica 2015年第5期31卷 698-707页

作者： Joon-Hyung Kim uk-Hee Jung sung Kim Joon-Yong Yoon Young-Seok choi Department of Mechanical Design Engineering Hanyang University Thermal & Fluid System R&BD Group Korea Institute of Industrial Technology Energy System Engineering University of Science and Technology

The venturi meter has an advantage in its use,because it can measure flow without being much affected by the type of the measured fluid or flow ***,it has excellent versatility and is being widely applied in many *** flow of a liquid containing air is a representative example of a multiphase flow and exhibits complex flow *** particular,the greater the gas volume fraction（GVF）,the more inhomogeneous the flow *** a result,using a venturi meter to measure the rate of a flow that has a high GVF generates an *** this study,the cause of the error occurred in measuring the flow rate for the multiphase flow when using the venturi meter for analysis by *** ensure the reliability of this study,the accuracy of the multiphase flow models for numerical analysis was verified through comparison between the calculated results of numerical analysis and the experimental *** a result,the Grace model,which is a multiphase flow model established by an experiment with water and air,was confirmed to have the highest ***,the characteristics of the internal flow Held about the multiphase flow analysis result generated by applying the Grace model were analyzed to find the cause of the uncertainty occurring when measuring the flow rate of the multiphase flow using the venturi meter.A phase separation phenomenon occurred due to a density difference of water and air inside the venturi,and flow inhomogeneity happened according to the flow velocity difference of each *** was confirmed that this flow inhomogeneity increased as the GVF increased due to the uncertainty of the flow measurement.

关键词： Multiphase flow Measurement Numerical analysis Venturi meter Gas volume fraction(GVF) Uncertainty Multiphase flow model Grace model