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Development of Renewable Woodceramics Synthesized from Cashew Nuts Shell Oil

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Open Journal of Composite Materials 2021年第2期11卷 23-30页

作者： toshihiro okabe kouji Fukuda Akito Takasaki Kazuhiko Kakishita Yuko Nishimoto Yoshikazu Shinohara Do Quang Minh Phan Dinh Tuan Ryoichi Yamamoto Department of Chemistry Faculty of Science Kanagawa University Kanagawa Japan Institue for Rura Engineering National Agriculture and Food Research Organization Ibaraki Japan Shibaura Institute of Technology Tokyo Japan Polytechnic University Tokyo Japan National Institute for Materials Science Ibaraki Japan Ho Chi Minh City University of Technology Ho Chi Minh City Vietnam Ho Chi Minh City University of Natural Resources and Environment Ho Chi Minh City Vietnam Yamamoto Eco Products Laboratory Tokyo Japan

The international issue to be addressed towards realizing a low-carbon society is to reduce the amount of carbon-based underground reserves such as coal, petroleum, and coke, and strongly encouraged to use carbon neutral biomass-derived resources. Woodceramics is a hybrid porous carbon material composed of wood-based biomass and phenolic resin, characterized by high far-infrared emissivity and large specific surface area. Woodceramics has been studied as heating elements and humidity and gas sensors, etc. If this is applied to the inner walls of aging and grain drying furnaces for vegetables and fruits, both ripening and drying are greatly promoted and fossil fuels used in boilers can be significantly reduced. In fact, it can produce black garlic with far infrared rays using a woodceramics brick efficiently. Furthermore, as a substitute for phenolic resin, if plant-based liquefied materials from cashew nut shell oil can be prepared and can be used for manufacturing woodceramics, then all carbon neutral circulating woodceramics made from wood-based biomass is possible to manufacture. On the other hand, woodplastics is a composite material that can be made of wooden materials and plastics, and able to expect the effective use of wood-based biomass and waste plastics.

关键词： Cashew Nuts Shell Oil Biomass Wood Liquefaction Woodplastics Woodceramics

Gastric cancer incidence based on endoscopic Kyoto classification of gastritis

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世界胃肠病学杂志:英文版 2023年第31期29卷 4763-4773页

作者： Osamu Toyoshima toshihiro Nishizawa Shuntaro Yoshida Tatsuya Matsuno Gota Fujisawa Akira Toyoshima Hirotoshi Ebinuma Mitsuhiro Fujishiro Yutaka saito Hidekazu Suzuki Department of Gastroenterology Toyoshima Endoscopy ClinicTokyo 157-0066Japan Department of Gastroenterology and Hepatology International University of Health and WelfareNarita HospitalNarita 286-8520Japan Department of Colorectal Surgery Japanese Red Cross Medical CenterTokyo 150-8935Japan Department of Gastroenterology Graduate School of MedicineThe University of TokyoTokyo 113-8655Japan Division of Endoscopy National Cancer Center HospitalTokyo 104-0045Japan Division of Gastroenterology and Hepatology Department of Internal MedicineTokai University School of MedicineIsehara 259-1193Japan

BACKGROUND Gastric cancer(GC)incidence based on the endoscopic Kyoto classification of gastritis has not been systematically investigated using time-to-event *** To examine GC incidence in an endoscopic surveillance *** This study was retrospectively conducted at the Toyoshima Endoscopy *** who underwent two or more esophagogastroduodenoscopies were *** incidence was based on Kyoto classification scores,such as atrophy,intestinal metaplasia(IM),enlarged folds(EFs),nodularity,diffuse redness(DR),and total Kyoto *** ratios(HRs)adjusted for age and sex were calculated using a Cox hazard *** A total of 6718 patients were enrolled(median age 54.0 years;men 44.2%).During the follow-up period(max 5.02 years;median 2.56 years),GC developed in 34 *** average frequency of GCs per year was 0.19%.Kyoto atrophy scores 1[HR with score 0 as reference:3.66,95%confidence interval(CI):1.06 to 12.61],2(11.60,3.82-35.27),IM score 2(9.92,4.37-22.54),EF score 1(4.03,1.63-9.96),DR scores 1(6.22,2.65-14.56),and 2(10.01,3.73-26.86)were associated with GC incidence,whereas nodularity scores were *** total Kyoto scores of 4(HR with total Kyoto scores 0-1 as reference:6.23,95%CI:1.93 to 20.13,P=0.002)and 5-8(16.45,6.29-43.03,P<0.001)were more likely to develop GC,whereas the total Kyoto scores 2-3 were *** HR of the total Kyoto score for developing GC per 1 rank was 1.75(95%CI:1.46 to 2.09,P<0.001).CONCLUSION A high total Kyoto score(≥4)was associated with GC *** endoscopy-based diagnosis of gastritis can stratify GC risk.

关键词： Gastric cancer Gastritis Endoscopy Atrophy Intestinal metaplasia Kyoto classification

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网络互穿结构复合材料的研究进展

功能材料 2002年第1期33卷 22-25页

作者：谢贤清张荻范同祥 toshihiro okabe Takashi Hirose 上海交通大学金属基复合材料国家重点实验室上海200030 Industrial Research Institute of Aomori Prefecture

总结了国内外在网络互穿复合材料及其预制件的制备工艺方面的研究现状，并且指出了各种工艺的特点；评述了网络互穿结构复合材料组织的特征及其表征；着重介绍了网络互穿复合材料力学性能、热学性能和摩擦学性能等方面的研究成果。

关键词：复合材料网络互穿结构制备工艺组织特征性能特征

Evaluation of Sawdust and Rice Husks as Fillers for Phenolic Resin Based Wood-Polymer Composites

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Open Journal of Composite Materials 2018年第3期8卷 124-137页

作者： Marieme Josephine Lette Elhadji Babacar Ly Diene Ndiaye Akito Takasaki toshihiro okabe Graduate School of Engineering and Science Shibaura Institute of Technology 3-7-5 Toyosu Koto-ku Tokyo Japan UFR des Sciences Appliquées et de Technologie Université Gaston Berger de Saint-Louis Saint-Louis Sénégal Molecular Engineering Institute Kinki University 11-6 Kayanomori Iizuka Fukuoka Japan

We produced Wood-Polymer Composites (WPCs) with phenolic resin (PR) filled with saw dust (SD) and rice husks (RH) in a PR:fillerratio of 60:40 wt.%. RH and SD were grinded and sieved into particles μm. The aim of this research work was to evaluate sawdust and rice husks as fillers for sustainable phenolic resin based WPCs. Therefore, we investigated the thermal stability of PR/RH and PR/SD WPCs then we studied and compared the tensile, flexural properties of PR/SD and PR/RH WPCs samples, as well as their dimensional stability after water absorption test. Furthermore, through ultraviolet light exposure, we evaluated the effects of photo-oxidation on the water stability and mechanical properties of PR/RH and PR/SD WPCs samples compared to unexposed ones. PR filled with SD presented better mechanical properties compared to PR/RH WPCs samples. However, PR/RH WPCs showed good mechanical properties, and better thermal resistance and better water repulsion capabilities compared to PR/SD WPCs samples. Although, long time UV exposure ended up lowering considerably the mechanical properties and water resistance of PR/SD and PR/RH WPCs, both RH and SD offer great added value as fillers for PR based WPCs;SD having better interactions with PR matrix compared to RH.

关键词： Wood-Polymer Composite Phenolic Resin Sawdust Rice Husks Mechanical Properties Thermal Stability Ultraviolet Effects Water Absorption Properties

Hepatocellular carcinoma occurring in a Crohn’s disease patient

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World Journal of Gastroenterology 2010年第25期16卷 3215-3218页

作者： Mitsuaki Ishida Shigeyuki Naka Hisanori Shiomi Tomoyuki Tsujikawa Akira Andoh Tamio Nakahara Yasuharu saito Yoshi-hide Fujiyama Mikiko Takikita-Suzuki Fumiyoshi Kojima Machiko Hotta Tohru Tani Yoshimasa Kurumi Hidetoshi okabe Department of Clinical Lab-oratory Medicine and Division of Diagnostic Pathology Shiga University of Medical Science Otsu Shiga 520-2192 Japan Department of Surgery Shiga University of Medical Sci-ence Otsu Shiga 520-2192 Japan Department of Gastroenterology Shiga Uni-versity of Medical Science Otsu Shiga 520-2192 Japan Division of Endoscopy Shiga University of Medical Science Otsu Shiga 520-2192 Japan

We report a case of hepatocellular carcinoma (HCC) occurring in a patient with Crohn’s disease (CD) without chronic hepatitis or liver cirrhosis, and review the clinicopathological features of HCC in CD patients. A 37-year-old Japanese man with an 8-year history of CD and a medication history of azathioprine underwent resection of a liver tumor. The histopathology of the liver tumor was pseudoglandular type HCC. In the nonneoplastic liver, focal hepatocyte glycogenosis (FHG) was observed, however, there was no evidence of liver cirrhosis or primary sclerosing cholangitis. Only nine cases of HCC in CD patients have been reported previously in the English-language literature. Eight of 10cases (including the present case) had received azathioprine treatment, and four of these cases also showed FHG, which is considered a preneoplastic liver lesion, within the non-neoplastic liver. Although the precise mechanism of the development of HCC in CD patients is controversial, these results suggest that azathioprine therapy and FHG in the non-neoplastic liver contribute to the development of HCC. These findings also indicate that it is important to survey CD patients treated with prolonged azathioprine therapy for potential liver tumors.

关键词： Crohn’s disease Hepatocellular carcinoma Azathioprine Focal hepatocyte glycogenosis Hepato-carcinogenesis

A new test method to evaluate durability on slippage cracking of asphalt mixture at high temperature

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A new test method to evaluate durability on slippage crackin...

Cerebral aneurysms and inflammation

ISAP2012重载沥青路面和桥面铺装专题会议

作者： Tetsuo ENDOH Shinya YOKOTA Ken TOMISAWA Toshiyuki okabe toshihiro KANAI TRI Kajima road Co.Ltd.

＜正＞Asphalt pavements on bridge deck or porous asphalt pavements are often failed due to slippage cracking accompanying local flow *** of the causes is a lack of interface friction between the asphalt mixture for surface layer and the underlying *** order to reproduce the fatigue failure of an asphalt surface layer at high temperature due to the interface slippage,we developed a wheel tracking fatigue test method using a wheel tracking test device generally used in Japan,with no mold constraining the *** tests were conducted while

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Neuroimmunology and Neuroinflammation 2015年第1期2卷 55-58页

作者： toshihiro Yokoi Makoto saito Yayoi Yoshimura Keiichi Tsuji Kazuhiko Nozaki Department of Neurosurgery Shiga University of Medical ScienceShiga 520-2192Japan

Multiple inflammatory factors,playing a crucial role in cerebral aneurysm formation,have been *** necrosis factor‑alpha(TNF‑α)has been revealed to have a close connection with several risk factors that affect aneurysm *** expression in aneurysm walls of mRNA for TNF‑αhas been observed in *** therapeutic interventions to reduce the formation of cerebral aneurysms may include the inhibition of mediators of inflammation.

关键词： Cerebral aneurysm inflammation molecular biology

Epithelial-mesenchymal transition in gastroenterological cancer

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Journal of Cancer Metastasis and Treatment 2015年第1期1卷 183-189页

作者： Hirohisa okabe Kosuke Mima Seiya saito Hiromitsu Hayashi Katsunori Imai Hidetoshi Nitta Daisuke Hashimoto Akira Chikamoto Takatoshi Ishiko Toru Beppu Hideo Baba Department of Gastroenterological Surgery Graduate School of Life SciencesKumamoto UniversityKumamoto 860-8556Japan Department of Multidisciplinary Treatment for Gastroenterological Cancer Kumamoto University HospitalKumamoto 860-8556Japan.

Epithelial-mesenchymal transition(EMT)was first reported as an essential process in embryonic cells and later showed that cancer cells,regardless of the context,exhibited a similar phenomenon that was crucial for tumor *** cells lose their adhesive characteristic capacity which is necessary for their functions but gain a mesenchymal *** change from epithelial to the mesenchymal phenotype of cancer cells makes it difficult to understand the mechanism underlying cancer biology and tumor progression.A number of transcription factors involved in tumor cell EMT and microRNA-regulated EMT have been *** review discussed recent findings and new players in EMT in gastrointestinal *** the molecular mechanisms of tumor progression are sometimes context-dependent,the recent findings of EMT have been reviewed in a context-dependent manner.

关键词： Epithelial-mesenchymal transition gastrointestinal cancer microRNA transcription factor

A Single-Center Open-Label Single-Arm Study Evaluating Efficacy and Safety of Skin Adhesive Epinexus<sup>TM</sup>in Surgical Patients

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Modern Plastic Surgery 2017年第4期7卷 31-38页

作者： Kazuo Kishi Noriko Aramaki-Hattori Yoshiaki Sakamoto Keisuke okabe Tetsu Hayashida Maiko Takahashi Yuko Kitagawa Masataka saito Takeya Adachi Aki Honda Hiromitsu Jinno Department of Plastic and Reconstructive Surgery Keio University School of Medicine Tokyo Japan Department of Surgery Keio University School of Medicine Tokyo Japan Department of Dermatology Keio University School of Medicine Tokyo Japan Department of Surgery Teikyo University School of Medicine Tokyo Japan

Existing skin adhesives may, however, cause inflammatory response to toxicity of formaldehyde generated as hydrolysate of polycyanoacrylate (the main ingredient), delay in wound closure due to the adhesive’s flowing into the wound from the edges, or a wide scar. EpinexusTM (Mitsui Chemicals, Inc.), the skin adhesive used for this study, was developed to prevent these risks. For the method of this study, This was a single-center, open-label, single-arm, intervention study of an acrylate skin adhesive, EpinexusTM. The primary endpoint was safety. The secondary endpoints were wound closure, cosmetic outcome (Manchester Scar Scale), and usability. Failures and adverse events were also appropriately evaluated. As a result, there were no particular adverse events such as inflammatory findings, which demonstrated that there is no problem in safety. Some common adverse events were observed, but no adverse events for which a causal relationship cannot be ruled out or failures. As a conclusion, there was no problem in wound closure, cosmetic outcome, or usability. This was a pilot study of EpinexusTM of an ongoing, single-center, open-label, parallel-group, comparative study in 60 subjects comparing EpinexusTMwith an existing skin adhesive, Dermabond? Advanced.

关键词： Cosmetic Techniques Clinical Study Wounds and Injury