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SERS sensing for cancer biomarker:Approaches and directions

Bioactive Materials 2024年第4期34卷 248-268页

作者： Lorena Vázquez-Iglesias Giovanna Maria Stanfoca Casagrande Daniel García-Lojo Letícia Ferro Leal tien anh ngo Jorge Pérez-Juste Rui Manuel Reis Krishna Kant Isabel Pastoriza-Santos CINBIO Universidade de VigoCampus Universitario As Lagoas MarcosendeVigo 36310Spain Galicia Sur Health Research Institute(IIS Galicia Sur) 36310VigoSpain Molecular Oncology Research Center Barretos Cancer HospitalBarretosBrazil Barretos School of Medicine Dr.Paulo Prata-FACISB Barretos14785-002Brazil Vinmec Tissue Bank Vinmec Health Care SystemHanoiViet Nam Life and Health Sciences Research Institute(ICVS) School of MedicineCampus de GualtarUniversity of Minho4710-057 BragaPortugal ICVS/3B’s-PT Government Associate Laboratory 4710-057BragaPortugal

These days,cancer is thought to be more than just one illness,with several complex subtypes that require different screening *** subtypes can be distinguished by the distinct markings left by metabolites,proteins,miRNA,and *** illness management may be possible if cancer is categorized according to its *** order to stop cancer from spreading and posing a significant risk to patient survival,early detection and prompt treatment are *** cancer screening techniques are tedious,time-consuming,and require expert personnel for *** has led scientists to reevaluate screening methodologies and make use of emerging technologies to achieve better *** time and money saving techniques,these methodologies integrate the procedures from sample preparation to detection in small devices with high accuracy and *** its proven potential for biomedical use,surface-enhanced Raman scattering(SERS)has been widely used in biosensing applications,particularly in biomarker *** was given especially to the potential of SERS as a portable clinical diagnostic *** approaches to SERS-based sensing technologies for both invasive and non-invasive samples are reviewed in this article,along with sample preparation techniques and *** from these significant constraints in the detection approach and techniques,the review also takes into account the complexity of biological fluids,the availability of biomarkers,and their sensitivity and selectivity,which are generally *** ways to maintain sensing capabilities in clinical samples are being developed recently to get over this *** is known to be a reliable diagnostic method for treatment ***,there is still room for advancement in terms of portability,creation of diagnostic apps,and interdisciplinary AI-based ***,we will outline the current state of technological maturity f

关键词： Surface-enhanced Raman scattering(SERS) Cancer biomarkers Invasive and non-invasive biomarkers Point of care detection Microfluidic devices

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Comparative analysis on the fuel consumption prediction model for bulk carriers from ship launching to current states based on sea trial data and machine learning technique

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Journal of Ocean Engineering and Science 2021年第4期6卷 317-339页

作者： tien anh Tran Faculty of Marine Engineering Vietnam Maritime UniversityHaiphong 180000Vietnam Marine Research Institute Vietnam Maritime UniversityHaiphong 180000Vietnam

MARPOL 73/78,Chapter IV is considered to reveal the emission control engineering on *** probability model of the fuel oil consumption is established based on the machine learning *** proposed methods are applied into this research in order to establish the probability model of fuel oil *** combination of Monte Carlo(MC)simulation method with Artificial Neural Networks(ANNs)is an optimal solution to deal the fuel consumption of marine main diesel *** sample data has been established based on the Monte Carlo simulation *** model of fuel oil consumption is designed by Artificial Neural Network *** proposed prediction model of fuel oil consumption is based on a back-propagation training algorithm of ANNs *** research results of proposed model have been verified with the actual operation data that have been collected from a certain bulk carrier of VINIC shipping transportation company in *** collected data is the actual operation parameters from the noon-log report of voyage during two years of the *** probability model of fuel oil consumption for main diesel engine is very useful in the field of ships energy efficiency management with higher accurancy than the other previous models.

关键词： Shipping transportation Fuel consumption Monte Carlo method Artificial neural network Marpol 73/78

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Investigate the energy efficiency operation model for bulk carriers based on Simulink/Matlab

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Journal of Ocean Engineering and Science 2019年第3期4卷 211-226页

作者： tien anh Tran Faculty of Marine Engineering Vietnam Maritime UniversityHaiphong 180000Vietnam Marine Research Institute Vietnam Maritime UniversityHaiphong 180000Vietnam

The world is facing great challenges regarding the energy crisis and environmental *** of the main challenges is the increasing number of ships with a lot of different types and *** this research,it is essential to analyze the operational energy efficiency of sea-going ships since the previous studies have concentrated on the inland river *** working is carried out by analyzing of the energy efficiency operation for large size ships such as bulk carriers,container ships,*** on the resistance characteristics of different navigation environment factors.A numerical model of main engine energy efficiency operation was considered using the energy efficiency measure of IMO(International Maritime Organization),in particular using the Energy Efficiency Operational Indicator(EEOI)as a monitoring tool in this *** EEOI numerical model was established and simulated through Simulink/Matlab and verified by the collected data from a certain vessel in *** EEOI model was simulated under the different navigation environment conditions including various engine speed,wind speed,wave height,and water *** that,the simulation results of this research will be compared with experimental database of a certain bulk carrier namely M/V NSU JUSTICE 250,000 *** results indicated that it is important to consider the main engine speed appropriately in ship operation in order to save energy onboard and reduce the greenhouse gas emission problem.

关键词： Ship energy efficiency Bulk carrier Navigation environment EEOI IMO

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Simulation and analysis on the ship energy efficiency operational indicator for bulk carriers by Monte Carlo simulation method

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International Journal of Modeling, Simulation, and Scientific Computing 2020年第4期11卷 201-223页

作者： tien anh Tran Faculty of Marine Engineering Vietnam Maritime University Haiphong 180000Vietnam Marine Research Institute Vietnam Maritime University Haiphong 180000Vietnam trantienanhvimaru@***

The ship energy efficiency management is an important topic in the field of the energy management onboard and the exhaust gases emission *** advanced model plays a vital role to improve the ship energy efficiency management when considering the variable *** establishment of the ship energy efficiency model through energy efficiency operational indicator(EEOI)index has been conducted through Monte Carlo simulation method along with using the operation data of a bulk carrier.A bulk carrier is chosen,namely,M/V NSU JUSTICE 250,000 DWT of VINIC Shipping Transportation Company in *** research uses the real operational data to perform a statistical methodology which calculates the various factors used to calculate *** method is supported by Matlab program through the curve fitting *** normal distribution estimation and the kernel density estimation method are used for the parametric curve fitting and non-parametric curve fitting,*** average weather condition(wind speed and wave height)and the fouling condition of hull have been investigated and compared with the research *** validation of the proposed methods has been conducted through the study of the external factors influencing the research *** research result shows the optimal operational data for the fuel consumption at each certain *** paper is useful for the ship-owners and the ship-operators in the field of the ship energy efficiency management.

关键词： Energy efficiency of ships simulation and analysis bulk carrier Monte Carlo simulation EEOI.

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A research on the energy efficiency operational indicator EEOI calculation tool on M/V NSU JUSTICE of VINIC transportation company,Vietnam

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Journal of Ocean Engineering and Science 2017年第1期2卷 55-60页

作者： tien anh Tran School of Energy and Power Engineering Wuhan University or TechnologyWuhan 430063PR China Vietnam Maritime University 484 Lach TrayNgo QuyenHai PhongViet Nam

Nowadays,the development of science and technology brings the innovations and resolutions in aims with increasing the benefits and incomes for companies and ***,the development of nation’s economic associates with environmental *** the field of shipping transportation,the increasing in a number of ships operates then International Maritime Organization IMO’s regulations become gradually more tightly about the environmental ***-Energy Efficiency Operational Indicator is an operational measure tool for assessing the ship energy efficiency and CO 2 emission to the ***,the research status is about ships energy efficiency management also has the optimistic trends and more *** the world,there are a lot of ships energy efficiency researches in aim with enhancing the energy efficiency and environmental *** instance,the voyage optimization,increasing the propulsion efficiency of ships,reducing the resistances,***,in Vietnam,there are a lot of shipping transportation companies with different types of ship but the number of research about ships energy efficiency management also *** this research was carried out and applied the energy efficiency measure tool of International Maritime Organization(IMO)for assessing all ships in *** above workings were conducted by EEOI calculation tool for a certain ship with name M/V NSU JUSTICE 250,000 DWT of the VINIC Shipping Transportation Company,Vietnam.

关键词： Ship energy efficiency EOI SEEMP IMO Bulk carrier

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Comparative Study of Light Manipulation in Three-Level Systems Via Spontaneously Generated Coherence and Relative Phase of Laser Fields

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Communications in Theoretical Physics 2019年第8期71卷 947-954页

作者： Nguyen Huy Bang Le Nguyen Mai anh Nguyen tien Dung Le Van Doai Vinh University 182 Le Duan Street Vinh City Vietnam Nong Lam University Ho Chi Minh City Vietnam (Received March 21 2019revised manuscript

We present a comparative study of the control of group velocity in three-level atomic systems including Λ-, Ladder-, and V-types via spontaneously generated coherence(SGC) and relative phase of laser *** the steady regime, expressions of group index are derived as an analytical function of controllable parameters related to SGC and relative *** is shown that the group velocity can be further slowed down or speeded up under SGC in which modifications of group velocity due to the SGC in Λ-and V-systems are stronger than that in *** particular, when interference strength of SGC p increases from 0.7 to 1.0, the light propagation is switched from superluminal to subluminal modes(for Λ-and Ladder-systems) or from subluminal to superluminal modes(for Vsystem).In the presence of relative phase, the group velocity changes between subluminal and superluminal modes with a period of 2π.In resonant region, the largest positive value of group index reaches at the relative phase φ=π while the largest negative value of group index reaches at φ= 0 and 2π for the Λ-and Ladder-systems, otherwise, for the V-system the largest positive group index occurs at φ= 0 and 2π, and the largest negative group index occurs at φ=π.

关键词： electromagnetically induced transparency spontaneously generated coherence group velocity

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Intermetallic Evolution of Al–Si-Coated Hot Stamping Steel During Modified Electrically Assisted Rapid Heating

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Acta Metallurgica Sinica(English Letters) 2018年第12期31卷 1327-1333页

作者： Kieu-anh Dinh Sung-Tae Hong tien Viet Luu Moon-Jo Kim Heung Nam Han School of Mechanical Engineering University of Ulsan Liquid Processing & Casting R&D Group Korea Institute of Industrial Technology Department of Materials Science and Engineering RIAMSeoul National University

Modified electrically assisted(EA) rapid heating of Al–Si-coated hot stamping steel is suggested, and the intermetallic evolution in the coating during heating is experimentally investigated. In the modified EA rapid heating, a continuous electric current for a suitable duration is applied to a specimen to heat it to a temperature slightly below the melting temperature of the coating. The temperature of the specimen is then kept constant for a specified dwell time. The result of the microstructural analysis shows that the modified EA rapid heating could effectively increase the thickness of the intermetallic layer between the coating and steel substrate much faster than conventional furnace heating and induction heating. The effectiveness of EA rapid heating may be due to the athermal effect of the electric current on the mobility of atoms, in addition to the well-known resistance heating effect. EA rapid heating also provides a technical advantage in that partial austenization can be easily achieved by properly placing the electrodes, as demonstrated in the present study.

关键词： Hot stamping Electrically assisted rapid heating Partial austenization Al–Si-coated hot stamping steel

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Examining unobserved factors associated with red light running in Vietnam:A latent class model analysis

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Transportation Safety and Environment 2022年第1期4卷 110-122页

作者： tien Dung Chu Tomio Miwa Tuan anh Bui Quang Phuc Nguyen Quang Huy Vu Department of Highway and Traffic Engineering University of Transport and CommunicationsNo.3 Cau Giay StreetLang Thuong WardDong Da DistrictHanoi 10001Vietnam Institute of Materials and Systems for Sustainability Nagoya UniversityFuro-choChikusa-kuNagoya cityAichi Prefecture464-8603Japan

Red-light running(RLR)is a crucial violation that causes traffic accidents and *** factors that affect RLR is very significant to reduce the potential of this *** studies have paid considerable attention to the observable factors,but not to unobservable *** study aims to examine the effects of observable and unobservable factors on *** study uses a latent class model(LCM)to assign individuals into two classes—red-light-respectful and red-light-disrespectful road users—by surveying 751 respondents who use private transportation *** study incorporates psychological determinants into the LCM to account for unobservable *** contribution of this study is the in-depth investigation into law-respectful and law-disrespectful behaviours and intentional and unintentional *** a study has not yet been conducted in the existing *** addition,a comprehensive comparison of the LCM and a traditional ordered probit model was ***,the results suggest that the LCM is superior to the model that does not consider latent *** estimation results are in alignment with previous studies on RLR:males,younger drivers/riders,less educated road users and motorcyclists are more likely to run red *** analysis of the latent variables shows that surrounding conditions—the behaviour of other violators,the absence of traffic police,and long waiting times—increase the possibility of *** on these results,we provide suggestions to policymakers and traffic engineers:the implementation of enforcement cameras and penalties for violators are critical countermeasures to minimize the potential of RLR.

关键词： red light running(RLR) developing country latent class model(LCM) multiple indicator multiple cause(MIMIC)model latent variables(LVs) motorcycles(MCs) traffic violation

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Structural and luminescent properties of (Eu,Tb) PO_4·H_2O nanorods/nanowires prepared by microwave technique

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Journal of Rare Earths 2011年第12期29卷 1170-1173页

作者： Nguyen Thanh Huong Nguyen Duc Van Dinh Manh tien Do Khanh Tung Nguyen Thanh Binh Tran Kim anh Le Quoc Minh Institute of Materials Science Vietnam Academy of Science and Technology University of Engineering and Technology National University HanoiVietnam

Nanowires/nanorods of europium/terbium orthophosphate monohydrate with Eu^3＋ concentration of 6, 11, and 20 at.% were prepared by microwave synthesis method. The effects of Eu^3＋ doping concentration on structure, morphology and optical properties of nanomaterials were also investigated. The results showed that, for all studied Eu^3＋ doping concentrations, a single-crystalline phase of rhabdophane-type （Eu,Tb）PO4·H2O nanowires/nanorods was obtained by using microwave heating of an aqueous solution of terbium（Ⅲ） nitrate, europium（Ⅲ） nitrate and NH4H2PO4 with pH=2. The length and width of these nanowires/nanorods ranged from 150 to 300 nm and from 10 to 50 nm, respectively. The evidence of energy transfer from Tb^3＋ to Eu^3＋ due to the energy overlap between the donor Tb^3＋ and the acceptor Eu^3＋was observed obviously via a significant enhancement in the luminescent intensity of Eu^3＋. Keywords：

关键词： microwave technique nanowires/nanorods energy transfer fluorescence spectroscopy rare earths

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Behavior of noncircular tunnels excavated in stratified rock masses-Case of underground coal mines

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Journal of Rock Mechanics and Geotechnical Engineering 2019年第1期11卷 99-110页

作者： ngoc anh Do Daniel Dias Van Diep Dinh tien Tung Tran Van Canh Dao Viet Doan Dao Phuc Nhan Nguyen Department of Underground and Mining Construction.Faculty of Civil Engineering Hanoi University of Mining and Ceology School of Automotive and Transportation Engineering Hefei University of Technology Laboratory 35R Crenoble Alpes University

The amount of tunnels excavated along stratified/sedimentary rock masses in Quangninh coal mine area,Vietnam, is gradually increasing. Rock mass in Quangninh is characterized by beddings between rock layers. The behavior of stratified rock masses surrounding the tunnels depends on both the intact rock and the beddings between rock layers. The main characteristics of stratified rock masses that need to be considered are their heterogeneity and anisotropy. Depending on the dip angle of rock layers, movements and failure zones developed surrounding the tunnels can be asymmetrical over the vertical axis of tunnel. This asymmetry causes adverse behaviors of the tunnel structures. The objective of this study is to highlight convergences and yielded zones developed in rock masses surrounding noncircular tunnels in Quangninh coal mine area using a finite element method. The presence of bedding joints is explicitly simulated. The numerical results indicated that with the increase in dip angle of bedding joints, the stress asymmetry over the tunnel vertical axis increases. It gradually leads to an asymmetry of the failure zone surrounding the tunnel. An increase of rock mass quality means a decrease of rock mass sensitivity to the discontinuities. In addition,a dip angle of the bedding joints of approximately 45° could be considered as the critical angle at which the rock mass mechanism changes between sliding and bending.

关键词： Tunnel Bedding Stratification Anisotropic Heterogeneity

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