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STCF conceptual design report (Volume 1): Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai L.P.An R.Aliberti Q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.H.Bu F.M.Cai H.Cai j.j.Cao Q.H.Cao X.Cao Z.Cao Q.Chang K.T.Chao D.Y.Chen H.Chen H.X.Chen j.F.Chen K.Chen L.L.Chen P.Chen S.L.Chen S.M.Chen S.Chen S.P.Chen W.Chen X.Chen X.F.Chen X.R.Chen Y.Chen Y.Q.Chen H.Y.Cheng j.Cheng S.Cheng T.G.Cheng j.P.Dai L.Y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko j.M.Dias D.Z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.j.Du Z.G.Du L.M.Duan D.Epifanov Y.L.Fan S.S.Fang Z.j.Fang G.Fedotovich C.Q.Feng X.Feng Y.T.Feng j.L.Fu j.Gao Y.N.Gao P.S.Ge C.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong B.Gou W.Gradl j.L.Gu A.Guevara L.C.Gui A.Q.Guo F.K.Guo j.C.Guo j.Guo Y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han M.Han X.Q.Hao j.B.He S.Q.He X.G.He Y.L.He Z.B.He Z.X.Heng B.L.Hou T.j.Hou Y.R.Hou C.Y.Hu H.M.Hu K.Hu R.j.Hu W.H.Hu X.H.Hu Y.C.Hu j.Hua G.S.Huang j.S.Huang M.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.j.Huang Y.B.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.ji j.j.jia S.jia Z.K.jia H.B.jiang j.jiang S.Z.jiang j.B.jiao Z.jiao H.j.jing X.L.Kang X.S.Kang B.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev C.H.Li C.Li D.Y.Li F.Li G.Li G.Li H.B.Li H.Li H.N.Li H.j.Li H.L.Li j.M.Li j.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li S.Li T.Li W.j.Li X.Li X.H.Li X.Q.Li X.H.Li Y.Li Y.Y.Li Z.j.Li H.Liang j.H.Liang Y.T.Liang G.R.Liao L.Z.Liao Y.Liao C.X.Lin D.X.Lin X.S.Lin B.j.Liu C.W.Liu D.Liu F.Liu G.M.Liu H.B.Liu j.Liu j.j.Liu j.B.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.B.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long C.G.Lu j.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.j.Luo T.Luo X.F.Luo Y.H.Luo H.j.Lyu X.R.Lyu j.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko Z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng L.Peng X.Y.Peng X.j.Peng K.Peters S.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian C.F.Qiao j.j.Qin j.j.Qin L.Q.Qin X.S.Qin T.L.Qiu j.Rademacker C.F.Redmer H.Y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Normal University Wuhan 430079China Central South University Changsha 410083China China University of Geosciences Wuhan 430074China China University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(EPFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of Technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy Physics Center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 11 Pokrovsky Bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive Technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China jilin University Changch

The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STCF project in China is under development with an extensive R&D *** document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STCF detector conceptual design

Early developmental exposure to inorganic mercury does not alter affiliative behavior of adult prairie voles(Microtus ochrogaster)

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Integrative Zoology 2018年第6期13卷 761-768页

作者： Yue CHEN Robert LEWIS j.thomas CURTIS Department of Pharmacology and Physiology Oklahoma State University Center for Health SciencesTulsaOklahomaUK

Mercury chloride exposure through drinking water in adult male prairie voles(Microtus ochrogaster)has been shown to alter their social ***,we examined the potential disruption of adult social behavior in prairie voles that were exposed to 60 ppm mercury during early *** used a cross-fostering approach to test the effects of mercury exposure:(1)from conception until birth;(ii)from birth until weaning;and(iii)from conception until weaning,on adult affiliative *** and mercury-treated voles were given the option of remaining in an empty cage or affiliating with a same-sex conspecific in a 3-h choice *** found that early developmental mercury exposure had little if any effect on the reproductive success of breeder pairs or on affiliative behavior by either sex when subjects were tested as *** results suggest that,at least in the context of the behavior tested,the effects of early developmental exposure to mercury do not permanently alter adult prairie vole affiliative behavior,or do so in a way that is too subtle to be detected using the current testing paradigm.

关键词： behavioral testing metals toxicity social behavior prairie vole

Positron imaging systems for studying particulate, granular and multiphase flows

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Particuology 2012年第2期10卷 146-153页

作者： thomas W.Leadbeater David j.Parker joseph Gargiuli Positron Imaging Centre University of BirminghamEdgbastonBirmingham B152TTUKa

The University of Birmingham has pioneered and adapted the use of the medical imaging technique known as positron emission tomography （PET） to the study of particulate, granular and multiphase flows in industrial and physical processes, This paper provides a review of the PET and complimentary positron emission particle tracking （PEPT） techniques and details their application to the study of particulate sys- tems, The current state of the art, recent developments and example results from many of the applications to which these techniques have been applied are highlighted.

关键词： Positron emission particle tracking (PEPT)Particle dynamicsMulti-phase flow measurement

Evidence-based management of gastrointestinal diseases

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Gastroenterology Report 2015年第1期3卷 1-2页

作者： j.thomas Lamont Division of Gastroenterology Beth Israel Deaconess Medical CenterHarvard Medical SchoolDA-501330 Brookline AvenueBostonMA 02215USA

This special issue of Gastroenterology Report is directed at“Evidence-based management of gastrointestinal(GI)diseases”.Gastroenterologists are now using a range of diagnostic tests and therapies that were largely unavailable twenty years *** is a fast-moving field,with innovations being developed at a rapid *** in this issue are authoritative reviews on how to manage a wide variety of conditions that affect the GI and biliary tracts using both established and emerging technologies,with emphasis on evidence to support the best practices and to achieve the best possible outcomes for our patients;for example,much has changed as regards our diagnostic accuracy in celiac disease.

关键词： diseases gastrointestinal patients

The six-question Gastroesophageal Reflux Disease Questionnaire(GerdQ)cannot accurately quantify reflux and reflux-associated symptoms frequency

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Gastroenterology Report 2022年第1期10卷 683-684页

作者： thomas j.Hurr South Australian Reflux Research Unit AdelaideSouth AustraliaAustralia

The aim of this commentary is to demonstrate,using two examples,that the six-question Gastroesophageal Reflux Disease Questionnaire(GerdQ)cannot accurately quantify reflux and reflux-associated symptoms(RRAS)frequency... 详细信息

关键词： symptoms oesophageal Gerd

Modeling the Kinetics of Moisture Desorption from Safou Pulp [Dacryodes edulis (G. Don) ***] before the Oil Extraction Step

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Open journal of Applied Sciences 2024年第8期14卷 2050-2064页

作者： Anicet Frédéric Binaki Feueltgaldah Christian Bopoundza Bob Wilfrid Loumouamou Gueko Séraphin Nguié Eliane Thérèse Biassala thomas Silou Multidisciplinary Food and Nutrition Research Team Regional Center of Excellence in Food and Nutrition Faculty of Science and Technology Marien Ngouabi University Brazzaville Congo Process Engineering Laboratory UNESCO-ENSP Chair Marien Ngouabi University Brazzaville Congo CR2IE Chemistry and Technology Platform Higher School of Cataract Technology (EPrES) Brazzaville Congo

The aim of this work is to model the drying kinetics of Safou pulp with or without endocarp using a phenomenological approach. Oven-drying kinetics at 70˚C, 90˚C and 105˚C were monitored using the curves given by the reduced mass as a function of time, which are modeled according to the Avrami/page, Fick and Peleg models using OringinPro 2018 software. The results showed that parameters k and n of the Avrami/Page model vary very little with fruit size and drying temperature (0.0018 ± 0.0002 k n k (Avrami model/page) were virtually identical, while b (Fick model) and n (Avrami model/page) were virtually identical for the same sample. For the Peleg model, the parameter a, varies from 0.0018 ± 0.0002 to 0.03328 ± 0.0079, with a ratio of 18.6 for all experimental conditions studied. However, with 0.977 R2 χ2 < 0.00002, we have a good fit of the model to the experimental data. The same applies to parameter b, which ranges from 0.82 ± 0.05 to 1.21 ± 0.02. Thus, drying modeling by these three models can be used to describe and predict the progress of oven-drying of safou pulp.

关键词： Drying Modeling Empirical Models Dacryodes edulis Congo Basin

High Oxygen Nanocomposite Barrier Films Based on Xylan and Nanocrystalline Cellulose

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Nano-Micro Letters 2010年第4期2卷 235-241页

作者： Amit Saxena thomas j.Elder jeffrey Kenvin Arthur j.Ragauskas School of Chemistry and Biochemistry Georgia Institute of Technology USDA-Forest Service Southern Research Station Micromeritics Instrument Corporation

The goal of this work is to produce nanocomposite film with low oxygen permeability by casting an aqueous solution containing xylan,sorbitol and nanocrystalline *** morphology of the resulting nanocomposite films was examined by scanning electron microscopy and atomic force microscopy which showed that control films containing xylan and sorbitol had a more open structure as compared to xylan-sorbitol films containing sulfonated nanocrystalline *** average pore diameter,bulk density,porosity and tortuosity factor measurements of control xylan films and nanocomposite xylan films were examined by mercury intrusion porosimetry *** films reinforced with nanocrystalline cellulose were denser and exhibited higher tortuosity factor than the control xylan *** xylan films had average pore diameter,bulk density,porosity and tortuosity factor of 0.1730 μm,0.6165 g/ml,53.0161% and 1.258,respectively as compared to xylan films reinforced with 50% nanocrystalline cellulose with average pore diameter of 0.0581 μm,bulk density of 1.1513 g/ml,porosity of 22.8906% and tortuosity factor of *** transmission rate tests demonstrated that films prepared with xylan,sorbitol and 5%,10%,25% and 50% sulfonated nanocrystalline cellulose exhibited a significantly reduced oxygen permeability of 1.1387,1.0933,0.8986 and 0.1799 cm^3×μm/m^2×d×k Pa respectively with respect to films prepared solely from xylan and sorbitol with a oxygen permeability of 189.1665 cm^3×μm/m^2×d×k *** properties suggested these nanocomposite films have promising barrier properties.

关键词： Nanocomposites Xylan Nanocrystalline cellulose Oxygen barrier

Isotretinoin for the treatment of nonobstructive azoospermia: a pilot study

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Asian journal of Andrology 2021年第5期23卷 537-540页

作者： john K Amory Charles H Muller thomas j Walsh Department of Medicine University of WashingtonSeattleWA 98195USA Department of Urology University of WashingtonSeattleWA 98195USA

The treatment of men with infertility from azoospermia is *** some men with severe oligozoospermia improve sperm output during treatment with isotretinoin,we treated nine men with azoospermia with isotretinoin to determine if azoospermic men would also respond to isotretinoin *** of these men who had a previous negative testicular sperm extraction(TESE)was found to have an area of sperm production on a postisotretinoin testicular *** man achieved a pregnancy and a live birth of a healthy,term daughter after in vitro fertilization coupled with intracytoplasmic sperm injection(IVF/ICSI).A second subject had a positive TESE after treatment as *** study of isotretinoin therapy in men with azoospermia undergoing testicular sperm harvesting procedures is warranted.

关键词： treatment injection pregnancy

Can inhibition of telomerase increase pancreatic cancer cell's susceptibility to chemotherapeutic reagents?

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Hepatobiliary & Pancreatic Diseases International 2002年第1期1卷 155-160页

作者： thomas j.Ⅲ Fahey Department of Surgery Cornell University Medical College New York NY USA

Objectives: To clarify the inhibition of pancreatic can-cer cells by interference with the hTR component of thetelomerase reverse transcriptase enzymatic complexand evaluate susceptibility of antisense hTR pancreaticcancer cells to chemotherapeutic ***: A 593 bp of full length hTR cDNA was sub-cloned into a mammalian expression vector pcDNA3.1(-) in antisense orientation to construct an antisensehTR expression plasmid. The plasmids were introducedinto Pancl cells, a human pancreatic carcinoma cellline, by lipofectin, and G418-resistant stable trans-formants were expanded. Resulting stable clones werescreened for the presence of hTR insert by PCR withT7 and BGH reverse primers located on the flanks ofthe multiclonal site of pcDNA3.1 vector. Cell growth rate,hTR expression, telomerase activity, and anchorage-in-dependent growth property were analyzed. Finally, sus-ceptibility of antisense hTR cells to chemotherapeuticreagents was ***: Significant downregulation of endogenous hTRwas evident in the antisense-hTR transformed cells,and telomerase activity was markedly decreased com-pared to control cells in standard TRAP assays. Fur-thermore, the proliferation and the anchorage-inde-pendent growth ability in antisense-hTR expressingcells were significantly decreased compared with thecontrol parental cells. However, no crisis or senescencephenomena was observed. Antisense hTR appears toincrease Pancl cell's susceptibility to chemotherapeuticreagent cDDP, but not to differentiation reagent DM-SO, COX2 inhibitor sulinbac, NS-398, curcumin, andchemotherapeutic reagent adriamycin(ADM).Conclusions: These data indicate that hTR is probablya critical component of human telomerase activity andthat downregulation of the RNA component of humantelomerase is an effective target for anticancer strategyand antisense hTR can increase Pancl cell's susceptibilityto cDDP.

关键词： Telomerase hTR Antisense Pancreatic carcinoma cellline chemotherapeutic reagents