Early developmental exposure to inorganic mercury does not alter affiliative behavior of adult prairie voles(Microtus ochrogaster)

作     者：Yue CHEN Robert LEWIS J.Thomas CURTIS 

作者机构：Department of Pharmacology and PhysiologyOklahoma State University Center for Health SciencesTulsaOklahomaUK 

出 版 物：《Integrative Zoology》 (整合动物学（英文版）)

年 卷 期：2018年第13卷第6期

页      面：761-768页

核心收录：

学科分类：0710[理学-生物学] 050203[文学-法语语言文学] 0502[文学-外国语言文学] 05[文学] 0905[农学-畜牧学] 0906[农学-兽医学] 

基　　金：This work was supported in part by a grant from The Eunice Kennedy Shriver National Institute for Child Health and Development(HD48462) by a Robberson Summer Dissertation Fellowship from the Oklahoma State University Center for Health Sciences 

主　　题：behavioral testing metals toxicity social behavior prairie vole 

摘      要：Mercury chloride exposure through drinking water in adult male prairie voles(Microtus ochrogaster)has been shown to alter their social ***,we examined the potential disruption of adult social behavior in prairie voles that were exposed to 60 ppm mercury during early *** used a cross-fostering approach to test the effects of mercury exposure:(1)from conception until birth;(ii)from birth until weaning;and(iii)from conception until weaning,on adult affiliative *** and mercury-treated voles were given the option of remaining in an empty cage or affiliating with a same-sex conspecific in a 3-h choice *** found that early developmental mercury exposure had little if any effect on the reproductive success of breeder pairs or on affiliative behavior by either sex when subjects were tested as *** results suggest that,at least in the context of the behavior tested,the effects of early developmental exposure to mercury do not permanently alter adult prairie vole affiliative behavior,or do so in a way that is too subtle to be detected using the current testing paradigm.