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Antidiabetic and antioxidant activities of red seaweed Laurencia dendroidea

Asian Pacific Journal of Tropical Biomedicine 2019年第12期9卷 501-509页

作者： The Han nguy.n thi huyen nguy.n Van Minh nguy.n thi Lan Phuong nguy.n thi Van Anh Tran Anh Duy Do Sang Moo Kim Faculty of Food Technology Nha Trang University02 Nguyen Dinh Chieu StreetNha Trang CityKhanh HoaVietnam Quality Control Department Institute of Vaccines and Medical BiologicalsNha Trang CityKhanh HoaVietnam Faculty of Pharmacy University of Medicine and Pharmacy of Ho Chi Minh City41 Dinh Tien Hoang StreetHo Chi Minh CityVietnam Research Department of Marine Conservation Research Institute for Marine Fisheries224 Le Lai StreetHai Phong CityVietnam Department of Marine Food Science and Technology Gangneung-Wonju National University7 Jukheon-gilGangneung 25457Republic of Korea

Objective:To investigate antidiabetic and antioxidant activities of the extract and fractions from Vietnamese red seaweed Laurencia ***:The seaweed Laurencia dendroidea was extracted by using microwave-assisted extraction method in 80%*** seaweed extract was then fractionated using different solvents(n-hexane,chloroform,ethyl acetate,butanol and water).These obtained fractions were evaluated forα-glucosidase inhibitory and antioxidant *** activities were tested using DPPH,nitric oxide radical scavenging and metal chelating *** enzyme inhibition mode was determined using Lineweaver-Burk *** acidic and thermal stabilities,the ethyl acetate fraction was treated at pH 2.0 and 100℃,*** residual inhibitory activity of the fraction was calculated based on the initial inhibitory *** in vivo antidiabetic activity,mice were divided into four groups,including normal control,diabetic control,diabetic mice treated with ethyl acetate fraction and diabetic mice treated with *** glucose level of treated mice during acute and prolonged treatments was *** evaluate the toxicity of the ethyl acetate fraction,the body weight changes and activities of liver function enzymes(aspartate transaminase,alanine transaminase and gammaglutamyl transferase)were carried ***:The extract of Laurencia dendroidea showed strongα-glucosidase inhibitory and DPPH radical scavenging *** concentrations affected bothα-glucosidase inhibitory and antioxidant activities.A 80%aqueous methanol was the suitable solvent for extraction of enzyme inhibitors and *** solvent fractions,ethyl acetate fraction had the highest inhibitory activities againstα-glucosidase with a mixed type of inhibition and the strongest antioxidant activities,and was stable under acidic and thermal *** ethyl acetate fraction treated diabetic mice significantly reduced blood glucose level compare

关键词： α-Glucosidase inhibitor Antidiabetic Antioxidant Red seaweeds Vietnam

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Sainfoin(Onobrychis viciifolia)silage in dairy cow rations reduces ruminal biohydrogenation and increases transfer efficiencies of unsaturated fatty acids from feed to milk

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Animal nutrition 2020年第3期6卷 333-341页

作者： nguy.n thi huyen Martin W.A.Verstegen Wouter H.Hendriks Wilbert F.Pellikaan Animal nutrition Group Wageningen UniversityPO Box 338Wageningen6700 AHthe Netherlands Department of Farm Animal Health Utrecht UniversityPO Box 80.163Utrecht3508 TDthe Netherlands

The effects of replacing grass silage by sainfoin silage in a total mixed ration(TMR)based diet on fatty acid(FA)reticular inflow and milk FA profile of dairy cows was *** experiment followed a crossover design with 2 dietary *** control diet consisted of grass silage,corn silage,concentrate and *** the sainfoin diet,half of the grass silage was replaced by a sainfoin *** rumen cannulated lactating multiparous dairy cows with a metabolic body weight of 132.5±3.6 kg BW^0.75,214±72 d in milk and an average milk production of 23.1±2.8 kg/d were used in the *** were paired based on parity and milk *** pairs,cows were randomly assigned to either the control diet or the sainfoin diet for 2 experimental periods(29 d per period).In each period,the first 21 d,cows were housed individually in tie-stalls for adaptation,then next 4 d cows were housed individually in climate-controlled respiration chambers to measure *** the last 4 d,cows were housed individually in tie stalls to measure milk FA profile and determine FA reticular inflow using the reticular sampling technique with Cr-ethylenediaminetetraacetic acid disodium salt dihydrate(EDTA)and Yb-acetate used as digesta flow *** the dietary C18:3n-3 intake was lower(P=0.025)in the sainfoin diet group,the mono-unsaturated FA reticular inflow was greater(P=0.042)in cows fed the sainfoin *** reticular inflow of trans-9,trans-12-C18:2 and cis-12,trans-10 C18:2 was greater(P≤0.024)in the sainfoin diet *** cows fed sainfoin diet had a lower(P≤0.038)apparent ruminal biohydrogenation of cis-9-C18:1 and C18:3n-3,compared to the cows fed the control *** sainfoin diet group had greater(P≤0.018)C18:3n-3 and cis-9,cis-12-C18:2 proportions in the milk FA profile compared to the control diet *** efficiencies from feed to milk of C18:2,C18:3n-3 and unsaturated FA were greater(P≤0.0179)for the sainfoin *** on the results,it co

关键词： Sainfoin silage Reticular inflow Milk fatty acid profile Dairy cow

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人类辅助生殖立法之中越比较法研究

人类辅助生殖立法之中越比较法研究

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作者：阮氏惠（nguy(?)n thi HU(?)）南京大学

学位级别：硕士

人类辅助生殖是现代医学技术发展的产物,它的出现为全世界的不育家庭带来了希望,对人类社会的发展具有积极意义。然而,人类辅助生殖方式打破了人类自然繁衍的规律,对社会传统伦理体系形成了冲击,也对现有的法律制度提出了新的要求。世... 详细信息

人类辅助生殖是现代医学技术发展的产物,它的出现为全世界的不育家庭带来了希望,对人类社会的发展具有积极意义。然而,人类辅助生殖方式打破了人类自然繁衍的规律,对社会传统伦理体系形成了冲击,也对现有的法律制度提出了新的要求。世界各国国情各异,因此目前对人类辅助生殖的立法现状也参差不一。中国和越南同为发展中国家,同处亚洲地区,两国国家体制相同,文化相近,且均深受儒家思想影响,因此对中越两国在人类辅助生殖方面的立法进行比较研究具有重要意义。本文采用比较法法学研究方法、立法解释方法和实证分析方法,对中越两国人类辅助生殖现行法律法规中的主要法律问题,譬如人类辅助生殖的理论基础、人类辅助生殖的法律关系、人类辅助生殖子女的法律地位、代孕的合法化等进行深入理论研究,在比较和探讨其各自特征及不足的基础上,从越南的立法经验,提出关于人类辅助生殖的立法构想。论文共分为五部分:第一部分为引言。本部分主要通过介绍中越两国近年来在人类辅助生殖方面较典型的司法实践纠纷案件引出有关代表性的问题,其中包括人类辅助生殖子女法律地位纠纷、精卵和胚胎权利归属纠纷及代孕法律纠纷等问题,了解这些案例有助于本文中对人类辅助生殖关键问题的立法论证。第二部分为人类辅助生殖概述。主要对人类辅助生殖的定义、历史发展和医学分类进行简要介绍。第三部分为中越人类辅助生殖立法的理论基础。本部分分别从哲学层面和法理层面分析论证中越进行人类辅助生殖立法的理论基础。东方文化和儒家思想在一定程度上限制了两国接受人类辅助生殖的态度,但从"人本"的现代宪法制度出发,生育自由应当作为一项基本人权,受到法律的认可和保护。这种权利应当作为中国和越南进行人类辅助生殖立法的法理学基础。第四部分为中越人类辅助生殖之立法现状。本部分主要介绍和比较了中越两国人类辅助生殖立法的现状及异同。综观中越两国的立法现状,可知两国均认可人工授精和体外授精为合法,而对代孕问题上,两国存在较大分歧。中国对任何形式的代孕均一律禁止,而越南则将非商业性代孕合法化,并确认代孕母亲的法律地位和代孕协议的法律效力。另外在确认人类辅助生殖子女法律身份方面,越南已明确进行立法,其中也包括代孕子女法律身份在内,而中国则尚未对此问题作出立法。第五部分为中越人类辅助生殖立法之探讨。本部分主要探讨中越两国在人类辅助生殖方面各自立法的特征及缺陷,并对中越两国相关立法提出一些建议。

关键词：人类辅助生殖人工授精体外受精代孕中越立法比较法

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Synchronous rectal adenocarcinoma and intestinal mantle cell lymphoma:A case report

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World Journal of Clinical Cases 2023年第24期11卷 5772-5779页

作者： Kim-Van Vu nguy.n-Van Trong nguy.n-thi Khuyen Do huyen nga Hoang Anh nguy.n Tien Trung PhamTrung Thong nguy.n Minh Duc Department of General Surgery Vietnam National Cancer HospitalHa Noi 100000Viet Nam Department of Practical Surgery Hanoi Medical UniversityHa Noi 100000Viet Nam Department of Oncology Hanoi Medical UniversityHa Noi 100000Viet Nam Pathology and Molecular Biology Center Vietnam National Cancer HospitalHa Noi 100000Viet Nam Department of Hematologic Oncology Vietnam National Cancer HospitalHa Noi 100000Viet Nam Department of Radiology Pham Ngoc Thach University of MedicineHo Chi Minh City 700000Viet Nam

BACKGROUnD Mantle cell lymphoma(MCL)of the gastrointestinal tract is a rare malignancy,accounting for about 0.2%of malignant colorectal *** synchronous with rectal adenocarcinoma is extremely *** know of only a few cases reported in the *** describe the case of a patient with synchronous rectal adenocarcinoma and intestinal *** SUMMARY A 63-year-old man was admitted to our hospital due to abdominal pain and hematochezia over the past *** patient was diagnosed with middle rectal cancer cT2n0M0 and underwent ***,we found a large tumor in the small intestine during *** patient underwent total mesorectal excision for rectal cancer and resectioning of the ileal segment containing the large *** and immunohistochemistry revealed the presence of both rectal adenocarcinoma and pathognomonic MCL stage IIE presenting as multiple lymphomatous *** patient subsequently underwent RDHAP/RCHOP chemotherapy and was maintained with rituximab.A Positron Emission Tomography and Computed Tomography(PET/CT)scan showed that the disease responded well to treatment without tumor-increased metabolism in the gastrointestinal *** Synchronous rectal adenocarcinoma and intestinal MCL presenting as multiple lymphomatous polyposis are extremely *** is often discovered fortuitously when rectal cancer is *** coexistence of these tumors poses treatment challenges.

关键词： Mantle cell lymphoma Multiple lymphomatous polyposis Rectal adenocarcinoma Synchronous Gastrointestinal tract Case report

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Clinical outcomes of patients with chronic hepatitis C after generic direct-acting antiviral treatments in Vietnam: A retrospective analysis

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Asian Pacific Journal of Tropical Medicine 2020年第11期13卷 487-493页

作者： Huong TT Vu Azumi Ishizaki Quynh T nguy.n huyen n nguy.n Hoi T Le Kinh V nguy.n Hiroshi Ichimura national Hospital for Tropical Disease HanoiVietnam Department of Viral Infection and International Health Graduate School of Medical SciencesKanazawa UniversityJapan

Objective:To evaluate the outcomes of generic direct-acting antiviral treatments for chronic hepatitis C in ***:The medical records of 522 patients(median 45 years;Female,25.3%)with chronic hepatitis C treated at a tertiary hospital in northern Vietnam in 2016 were retrospectively ***:Female patients were significantly older than male patients(median 52,IQR 41-59 vs.43 years,IQR:39-55;Png 522 patients,49.4%were infected with hepatitis C virus(HCV)genotype 6,followed by 1 a(19.0%),1 b(13.0%),and 3(5.9%).Coinfection with hepatitis B virus or human immunodeficiency virus was noted in 5.8%and 3.1%of patients,*** were treated with ledipasvir/sofosbuvir with or without ribavirin(70.9%),sofosbuvir/pegylated-interferon+ribavirin(13.2%),daclatasvir/sofosbuvir with or without ribavirin(12.5%),or sofosbuvir/ribavirin(3.4%),and 96.4%(n=503)completed the direct-acting antiviral *** patient discontinued treatment due to adverse event(s).A sustained virologic response 12 weeks after the end of the treatment(SVR12)was evaluated in 62.6%of *** sustained virologic response 12 weeks after the end of the treatment was 98.7%regardless of HCV genotypes or direct-acting antiviral *** severity of liver stiffness was significantly decreased from 10.2 to 6.3 kilopascals measured by transient elastography by the treatment(Png patients who completed the directacting antiviral treatment,17.7%returned for further follow-ups after ***:In Vietnam,the current generic direct-acting antiviral treatment for chronic hepatitis C was effective regardless of HCV genotypes and direct-acting antiviral regimens with the attenuation of liver *** is feasible to implement direct-acting antiviral treatment to cure chronic hepatitis C patients at any liver fibrosis stages in Vietnam.

关键词： Vietnam Chronic hepatitis C Generic direct-acting antiviral Improvement of liver stiffness

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Studies on the Combination of Some Selected Microorganisms for Biodegradation of Cassava Peel Wastes （Manihot Esculenta）

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Journal of Environmental Science and Engineering(B) 2016年第7期5卷 342-347页

作者： Thanh Tran Vo Duy Minh Do Vu Thanh Son Le thi Anh Hong Hong n-hung Do nguy.n Dinh Duc nguy.n thi Bach huyen nguy.n thi Van Ha nTT Hi-Tech Institute Nguyen Tat Thanh University HCM City 700000 Vietnam Faculty of Environment Ho Chi Minh City University of Natural Resources and Environment HCM City 700000 Vietnam Institute of Tropical Biology Vietnam Academy of Science and Technology HCM City 700000 Vietnam

Cassava peel has a lot of nutrients which can be utilized as fertilizer in agriculture. However, high cellulose contents may cause difficulty for organic digestion and slow down the nutrient absorption for plants. this study aims to reach the microorganisms or their combination for biodegradating the cassava peel waste. The initial result shows that after 21 days the glucose concentration in all samples was the highest during experiment times. The reducing glucose produced in mg/mL by the selected bacteria was 9.32, higher than the selected fungie of 1.57 mg/mL. The percentage degradation of cassava peel weigh was the highest for fungi which was 52% of weigh, respectively. Meanwhile, bacteria only degradated about 31.6% after 4 weeks. However, the combination between bacteria and fungi provides the highest glucose concentration, 19.29 mg/mL and digests 62% of the mass cassava in experiment. this study suggests that biodegradation of agro-wastes in the environment to reduce biomass waste pollution is very promising.

关键词： Biodegradation bacteria cassava peel wastes fungi.

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The Serum Level of CD16 + 56 in Zona

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Journal of Cosmetics, Dermatological Sciences and Applications 2021年第1期11卷 1-9页

作者： nguy.n Lan Anh Bùi Thị Vân Vũ Thu Trang Đặng Trung Thành nguy.n Thị Quỳnh Trang nguy.n Thị Tuấn Đặng Văn Em Department of Dermatology Venereology Allergy 108 Military Central Hospital Ha Noi Vietnam Department of Immunology 108 Military Central Hospital Ha Noi Vietnam

Objectives: To study the change of CD16 + 56 in zona. Materials and Methods: 62 zona patients admitted at Inpatient Department of Dermatology, Venereology Allergy, 108 Military Central Hospital, and 30 healthy volunte... 详细信息

ng>Objectives:ng> To study the change of CD16 + 56 in zona. ng>Materials and Methods:ng> 62 zona patients admitted at Inpatient Department of Dermatology, Venereology Allergy, 108 Military Central Hospital, and 30 healthy volunteers who were matched for age and sex participated in this study. Prospective, cross-sectional study with controls was conducted. We measured the number of CD16 + CD56 by flow cytometry using FACS Callibur. ng>Results:ng> The mean level of CD16 + 56 in zona patients was 253 ± 200 (106 cells/l), which was lower than that of control group but then increased after treatment. The change of CD16 + 56 did not correlate with patients’ age. Patients who were in severe condition or had affected size from 3% or more had a lower number of CD16 + 56 than control group. ng>Conclusion:ng> The number of CD16 + 56 in zona patients were lower than that of healthy people.

关键词： CD16 + 56 Zona

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1,3-戊二烯阳离子聚合反应动力学

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高分子材料科学与工程 1998年第3期14卷 12-15页

作者：彭宇行 nguy.,HA 中国科学院成都有机化学研究所

研究了以Ａｌ（ＯＴｆ）３引发的１，３－戊二烯（ＰＤ）在二氯甲烷和正己烷中的阳离子聚合动力学。根据聚合反应引发速度快并呈现转化率不完全的实验事实，提出了快速引发活性中心浓度逐渐降低的非稳态假定，根据这个假定推导出的非稳... 详细信息

研究了以Ａｌ（ＯＴｆ）３引发的１，３－戊二烯（ＰＤ）在二氯甲烷和正己烷中的阳离子聚合动力学。根据聚合反应引发速度快并呈现转化率不完全的实验事实，提出了快速引发活性中心浓度逐渐降低的非稳态假定，根据这个假定推导出的非稳态动力学方程能较好地与实验数据相吻合。在二氯甲烷中链增长反应速度大于在正己烷中的速度，而链终止反应在二氯甲烷中的速度小于正己烷中的速度，因此在二氯甲烷中聚合反应呈现较高的反应速率及转化率。还研究了同样条件下由ＡｌＣｌ３引发的ＰＤ聚合反应动力学／．与Ａｌ（ＯＴｆ）３相比，ＡｌＣｌ３引发体系呈现较高的聚合速率和较低的转化率。

关键词：戊二烯阳离子聚合动力学聚合

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巨峰和无核早红葡萄在越南谅山试种观察

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南方农业学报 2014年第7期45卷 1225-1229页

作者：黄江流 PHAM thi Thang 罗瑞鸿 nguy.n thi Hà 吕荣华 LUOnG Dǎng ning CHU Vǎn DUòng nguy.n Manh Tòng 彭宏祥 Ly Ming nguyet LU'O'nG i Thuy CHU Xun Tien VI Vǎn Dúc nguy.n Duy Dng Ly Dúc Khiêm 熊俏广西农业科学院园艺研究所广西农业科学院葡萄与葡萄酒研究所广西农业科学院国际合作处南宁530007 越南谅山省科技厅越南谅山省科技厅科技进步应用中心

[目的]观察巨峰、无核早红葡萄在越南谅山省的引种表现,为其在越南推广种植提供参考依据.[方法]2009年春从中国南宁引入巨峰、无核早红两个鲜食葡萄品种在越南谅山省试种,调查其枝蔓生长量、物候期、果实性状、产量等相关指标.[结果]至... 详细信息

[目的]观察巨峰、无核早红葡萄在越南谅山省的引种表现,为其在越南推广种植提供参考依据.[方法]2009年春从中国南宁引入巨峰、无核早红两个鲜食葡萄品种在越南谅山省试种,调查其枝蔓生长量、物候期、果实性状、产量等相关指标.[结果]至第1年抚育冬季,巨峰葡萄枝蔓总长234.5 cm,上架茎粗0.84 cm;无核早红葡萄枝蔓总长294.1 cm,上架茎粗0.86 cm.在物候期方面,巨峰葡萄从萌芽至果实成熟需141～151 d,表现中熟;无核早红从萌芽至果实成熟需142～151 d,未表现其应有的早熟特性.在果实性状方面,巨峰葡萄2010～2012年3年平均单果重8.9 g,种子数1.04粒,可溶性固形物（TSS）含量17.5％;无核早红葡萄2010～2012年3年平均单果重6.8 g,TSS含量13.9％.在产量方面,巨峰葡萄2010～2012年产量分别为13.69、17.50和16.24 t/ha;无核早红葡萄2010～2012年产量分别为10.81、16.02和20.92t/ha.[结论]巨峰葡萄在越南谅山省种植表现丰产稳产优质,具有较好的适栽性,可大面积推广种植;无核早红葡萄表现丰产稳产,但表现低糖低酸,极易裂果,着色困难,不宜在越南大面积发展.

关键词：巨峰葡萄无核早红葡萄试种适栽性越南谅山省

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Industrial Revolution 4.0 in Some Countries Experiences and Lessons for Vietnam

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Journal of Mechanics Engineering and Automation 2020年第6期10卷 189-195页

作者： Trần ThịHải Vân Doãn Minh Quân nguy.n Duyên Phong Faculty of Information Technology Hanoi University of Mining and GeologyHanoi 10000Vietnam Departments of High Technology Ministry of Science and TechnologyHanoi 10000Vietnam Faculty of Construction Hanoi University of Mining and GeologyHanoi 10000Vietnam

The world has experienced 3 Industrial *** now,we are at the beginning of the 4th Industrial Revolution.4.0 Revolution is based on the digital revolution,characterized by the increasingly popular internet and mobile,by smaller and more powerful semiconductors at cheaper price and by Artificial *** technologies with computer hardware,software and networks are becoming more and more complex,more integrated,thus transforming *** with the unprecedented impact of the 4.0 Revolution,depending on the size of the economy and the level of technology,countries around the world have policies to adapt,catch up and take advantage of the achievements of the *** revolution serves the sustainable development of our *** article summarizes the policies of some countries such as Germany,the United States,Japan,Singapore,Republic of Korea,India,China,Taiwan,...under the impact of the 4.0 Revolution;thereby drawing lessons for Vietnam in the process of implementing the 4.0 Revolution to avoid negative impacts,take advantage of the pre-eminence of the revolution in socio-economic development.

关键词： The 4th Industrial Revolution revolution 4.0 industry 4.0 digitization high technology

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