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Effect of longer battery life on small bowel capsule endoscopy

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World Journal of Gastroenterology 2015年第9期21卷 2677-2682页

作者： George Ou Neal Shahidi Cherry Galorport Oliver Takach terry lee Robert Enns Division of Gastroenterology St. Paul’s HospitalUniversity of British ColumbiaPacific Gastroenterology AssociatesVancouver V6Z2K5British ColumbiaCanada Centre for Health Evaluation and Outcome Sciences University of British ColumbiaSt. Paul’s HospitalVancouver V6Z2K5British ColumbiaCanada

AIM:To determine if longer battery life improves capsule endoscopy(CE) completion ***:A retrospective study was performed at a tertiary,university-affiliated hospital in Vancouver,*** who underwent CE with either PillCamTM SB2 or SB2 U between 01/2010 and 12/2013 were considered for ***2 and SB2 U share identical physical dimensions but differ in their battery lives(8 h vs 12 h).Exclusion criteria included history of gastric or small bowel surgery,endoscopic placement of CE,interrupted view of major landmarks due to technical difficulty or significant amount of debris,and repeat CE using same *** demographics,comorbidities,medications,baseline bowel habits,and previous surgeries were *** of major landmarks in CE were recorded,and used to calculate gastric transit time,small bowel transit time,and total recording time.A complete CE study was defined as visualization of *** times and completion rates were ***:Four hundred and eight patients,including 208(51.0%) males,were included for *** mean age was 55.5 ± 19.3 *** most common indication for CE was gastrointestinal bleeding(n =254,62.3%),followed by inflammatory bowel disease(n =86,21.1%).There was no difference in gastric transit times(group difference 0.90,95%CI:0.72-1.13,P =0.352) and small bowel transit times(group difference 1.07,95%CI:0.95-1.19,P =0.261) between SB2 U and SB2,but total recording time was about 14% longer in the SB2 U group(95%CI:10%-18%,P < 0.001) and there was a corresponding trend toward higher completion rate(88.2% vs 93.2%,OR =1.78,95%CI 0.88-3.63,P =0.111).There was no statistically significant difference in the rates of positive findings(OR =0.98,95%CI:0.64-1.51,P =0.918).CONCLUSION:Extending the operating time of CE may be a simple method to improve completion rate although it does not affect the rate of positive findings.

关键词： Capsule endoscopy Battery life Completionrate Posi

Metallosis with spinal implant loosening after spinal instrumentation:A case report

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World Journal of Orthopedics 2023年第8期14卷 651-661页

作者： Yiu Hin Kwan Hong lee terry Teo Shree Kumar Dinesh Wee Lim Loo Department of Orthopaedic Surgery Changi General HospitalSingapore 529889Singapore

BACKGROUND Spinal metallosis is a rare complication following spinal instrumentation whereby an inflammatory response to the metal implants results in the development of granulomatous *** SUMMARY We describe the case of a 78-year-old woman who had recurrence of back pain 5 years after lumbar spine posterior decompression and instrumented *** spine radiographs showed hardware loosening and magnetic resonance imaging showed adjacent segment *** surgery revealed evidence of metallosis *** Spinal metallosis can present several years after *** and computed tomography may demonstrate hardware loosening secondary to *** metal concentrations associated with spinal metallosis have yet to be ***,metallosis is still an intraoperative and histopathological *** presence of metallosis after spinal instrumentation likely indicates a more complex underlying problem:Pseudarthrosis,failure to address sagittal balance,infection,and cross-threading of set ***,identifying metallosis is important,but initiating treatment promptly for symptomatic implant loosening is of greater paramount.

关键词： Metallosis Spine Instrumentation Implant loosening Corrosion Case report

FOCUS: Future of fecal calprotectin utility study in inflammatory bowel disease

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World Journal of Gastroenterology 2016年第36期22卷 8211-8218页

作者： Greg Rosenfeld Astrid-Jane Greenup Andrew Round Oliver Takach Lawrence Halparin Abid Saadeddin Jin Kee Ho terry lee Robert Enns Brian Bressler Department of Medicine Division of Gastroenterology St. Paul’s Hospital University of British Columbia Vancouver Department of Medicine Division of Gastroenterology Prince George Regional Hospital University of British Columbia Department of Medicine Division of Gastroenterology Lion’s Gate Hospital University of British Columbia Centre for Health Evaluation and Outcome Sciences St Paul’s Hospital

AIM To evaluate the perspective of gastroenterologists regarding the impact of fecal calprotectin(FC) on the management of patients with inflammatory bowel disease(IBD).METHODS Patients with known IBD or symptoms suggestive of IBD for whom the physician identified that FC would be clinically useful were recruited. Physicians completed an online "pre survey" outlining their rationale for the test. After receipt of the test results, the physicians completed an online "post survey" to portray their perceived impact of the test result on patient management. Clinical outcomes for a subset of patients with follow-up data available beyond the completion of the "post survey" were collected and *** Of 373 test kits distributed, 290 were returned, resulting in 279 fully completed surveys. One hundred and ninety patients were known to have IBD; 147(77%) with Crohn's Disease, 43(21%) Ulcerative Colitis and 5(2%) IBD unclassified. Indications for FC testing included: 90(32.2%) to differentiate a new diagnosis of IBD from Irritable Bowel Syndrome(IBS), 85(30.5%) to distinguish symptoms of IBS from IBD in those known to have IBD and 104(37.2%) as an objective measure of inflammation. FC levels resulted in a change in management 51.3%(143/279) of the time which included a significant reduction in the number of colonoscopies(118) performed(P < 0.001). Overall, 97.5%(272/279) of the time, the physicians found the test sufficiently useful that they would order it again in similar situations. Follow-up data was available for 172 patients with further support for the clinical utility of FC *** The FC test effected a change in management 51.3% of the time and receipt of the result was associated with a reduction in the number of colonoscopies performed.

关键词： Inflammatory bowel disease Biomarkers Fecal calprotectin Colonoscopy Physician perspective

Evaluation of a deep learning supported remote diagnosis model for identification of diabetic retinopathy using wide-field Optomap

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Annals of Eye Science 2022年第2期7卷 93-104页

作者： terry lee Mingzhe Hu Qitong Gao Joshua Amason Durga Borkar David D’Alessio Michael Canos Afreen Shariff Miroslav Pajic Majda Hadziahmetovic Department of Ophthalmology Duke University Medical CenterDurhamNCUSA Department of Electrical and Computer Engineering Duke UniversityDurhamNCUSA Department of Endocrinology Duke University Medical CenterDurhamNCUSA

Background:We test a deep learning(DL)supported remote diagnosis approach to detect diabetic retinopathy(DR)and other referable retinal pathologies using ultra-wide-field(UWF)***:Prospective,non-randomized study involving diabetic patients seen at endocrinology ***-expert imagers were trained to obtain non-dilated images using UWF *** were graded by two retina specialists and classified as DR or incidental retinal ***’s kappa was used to test the agreement between the remote diagnosis and the gold standard exam.A novel DL model was trained to identify the presence or absence of referable pathology,and sensitivity,specificity and area under the receiver operator characteristics curve(AUROC)were used to assess its ***:A total of 265 patients were enrolled,of which 241 patients were imaged(433 eyes).The mean age was 50±17 years,45%of patients were female,34%had a diagnosis of diabetes mellitus type 1,and 66%of type *** average Hemoglobin A1c was 8.8±2.3%,and 81%were on *** the 433 images,404(93%)were gradable,64 patients(27%)were referred to a retina specialist,and 46(19%)were referred to comprehensive ophthalmologist for a referable retinal pathology on remote ***’s kappa was 0.58,indicating moderate *** DL algorithm achieved an accuracy of 82.8%(95%CI:80.3-85.2%),a sensitivity of 81.0%(95%CI:78.5-83.6%),specificity of 73.5%(95%CI:70.6-76.3%),and AUROC of 81.0%(95%CI:78.5-83.6%).Conclusions:UWF Primary can be used in the non-ophthalmology setting to screen for referable retinal pathology and can be successfully supported by an automated algorithm for image classification.

关键词： Retina screening imaging deep learning(DL) diabetic retinopathy(DR)

Verification and Dosimetric Impact of Acuros XB Algorithm for Stereotactic Body Radiation Therapy (SBRT) and RapidArc Planning for Non-Small-Cell Lung Cancer (NSCLC) Patients

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2013年第1期2卷 6-14页

作者： Suresh Rana Kevin Rogers terry lee Daniel Reed Christopher Biggs Department of Medical Physics ProCure Proton Therapy Center Oklahoma City USA Department of Radiation Oncology Arizona Center for Cancer Care Peoria USA

Purpose: The experimental verification of the Acuros XB (AXB) algorithm was conducted in a heterogeneous rectangular slab phantom, and compared to the Anisotropic Analytical Algorithm (AAA). The dosimetric impact of the AXB for stereotactic body radiation therapy (SBRT) and RapidArc planning for 16 non-small-cell lung cancer (NSCLC) patients was assessed due to the dose recalculation from the AAA to the AXB. Methods: The calculated central axis percentage depth doses (PDD) in a heterogeneous slab phantom for an open field size of 3 ×3 cm2 were compared against the PDD measured by an ionization chamber. For 16 NSCLC patients, the dose-volume parameters from the treatment plans calculated by the AXB and the AAA were compared using identical jaw settings, leaf positions, and monitor units (MUs). Results: The results from the heterogeneous slab phantom study showed that the AXB was more accurate than the AAA;however, the dose underestimation by the AXB (up to ?3.9%) and AAA (up to ?13.5%) was observed. For a planning target volume (PTV) in the NSCLC patients, in comparison to the AAA, the AXB predicted lower mean and minimum doses by average 0.3% and 4.3% respectively, but a higher maximum dose by average 2.3%. The averaged maximum doses to the heart and spinal cord predicted by the AXB were lower by 1.3% and 2.6% respectively;whereas the doses to the lungs predicted by the AXB were higher by up to 0.5% compared to the AAA. The percentage of ipsilateral lung volume receiving at least 20 and 5 Gy (V20 and V5 respectively) were higher in the AXB plans than in the AAA plans by average 1.1% and 2.8% respectively. The AXB plans produced higher target heterogeneity by average 4.5% and lower plan conformity by average 5.8% compared to the AAA plans. Using the AXB, the PTV coverage (95% of the PTV covered by the 100% of the prescribed dose) was reduced by average 8.2% than using the AAA. The AXB plans required about 2.3% increment in the number of MUs in order to achieve the sa

关键词： Acuros XB AAA Heterogeneity Correction SBRT RapidArc Lung Cancer

Headaches Associated with N95 Mask Usage amongst Healthcare Workers in Operating Theatres during COVID-19 Pandemic: A Cross-Sectional Study

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Open Journal of Anesthesiology 2022年第5期12卷 184-195页

作者： Lydia Weiling Li Daryl Jian An Tan terry Hong lee Teo Jinlin Lin Department of Anaesthesiology and Surgical Intensive Care Changi General Hospital Singapore Department of Orthopaedic Surgery Changi General Hospital Singapore Department of General Upper GI and Bariatric Surgery Changi General Hospital Singapore

Introduction: N95 respirator masks are a cornerstone in the fight against the ongoing COVID-19 pandemic. However, its use has side effects such as headaches. The primary aim of this study is to identify factors that may contribute to higher occurrences of headaches with wearing N95 masks. Methods: A cross-sectional study was conducted across healthcare providers in operating theatres of a tertiary hospital based in Singapore involved in the care of COVID-19 patients. The study involved a self-administered online questionnaire completed by all participants. Results: 176 participants were included into the study, of which 65 (36.9%) reported headaches associated with wearing N95 masks. Out of the 65 participants who experienced headaches, 28 (43.1%) reported experiencing “mild” headache, 30 (46.2%) reported experiencing “moderate” headache, and 7 (10.7%) reported experiencing “severe” headache. 44 participants (67.7%) reported that the headache has affected their work, and 20 participants (30.8%) required analgesia to relieve the headaches. Other symptoms associated with N95 mask usage include skin damage (12.3%), breathlessness (15.4%), giddiness (6.2%), nausea (6.2%) and ear pain (3.1%). Multivariate logistic regression analysis showed that participants younger than 32 years old (p = 0.001) and history of pre-existing headache disorders (p = 0.001) were associated with higher occurrences of headaches with wearing N95 masks. Conclusion: Our study showed that younger age and history of pre-existing headache disorders contribute to higher occurrences of headaches with N95 mask usage. These associations could be useful in identifying at-risk individuals so that precautions may be taken to reduce the occurrence of headaches when wearing N95 masks.

关键词： N95 Masks Headache COVID-19 Health-Care Workers Operating Theatre

Acuros XB Algorithm vs. Anisotropic Analytical Algorithm: A Dosimetric Study Using Heterogeneous Phantom and Computed Tomography (CT) Data Sets of Esophageal Cancer Patients

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Journal of Cancer Therapy 2013年第1期4卷 138-144页

作者： Suresh Rana Kevin Rogers Shyam Pokharel terry lee Daniel Reed Christopher Biggs Department of Radiation Oncology Arizona Center for Cancer Care Peoria USA Premiere Oncology Fort Myers USA

Our purpose in this study was to assess the dosimetric impact of the Acuros XB algorithm (AXB), in comparison with Anisotropic Analytical Algorithm (AAA) calculations, for esophageal cancer treatment plans created with RapidArc technique. First, we performed a phantom study by comparing the percent depth dose (PDD) calculated by AXB and AAA against the measured PDD in a slab phantom containing a 2 cmair gap thickness. Second, we performed a clinical study using a computed tomography (CT) data set from 10 esophageal cancer patients. The treatment plans calculated by AXB and AAA were evaluated for planning target volume (PTV) coverage, doses to the PTV and organs at risk (OARs). Dose calculations by the AXB and AAA were done for identical beam parameters. The AXB showed better agreement (within ±0.5%) with measurements than did the AAA (?4.9% to ?6.2%). In comparison to the AAA, the AXB predicted a higher maximum PTV dose (2.0%), but lower mean (1.1%) and minimum (2.5%) PTV doses as well as reduced PTV coverage (9.1%). The averaged mean doses to all OARs predicted by the AXB were lower (up to 3.6%), and the percentage of lungs volume receiving at least 20 and 5 Gy were lower by about 3.6% in the AXB plans compared to the AAA plans. The AXB is more accurate than the AAA for dose predictions when air medium is involved. The use of AXB is more likely to avoid dose overestimation or underestimation for the esophageal cancer treatment plans compared to AAA.

关键词： Acuros XB AAA Esophageal Cancer Heterogeneity Correction

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“全球省油冠军”

人民交通 2011年第2期 88-90页

作者： terry lee

这场比赛不同一般,旨在试探汽车极限,不比速度,不求马力,争的反而是一个不甚性感的头衔:"全球省油冠军"。美国威斯康辛州麦迪逊市,一个夏季的周六,停车场里头有十来个人围着一辆红色本田Insight,看着韦恩做准备。他即将参加油电混合动力... 详细信息

这场比赛不同一般,旨在试探汽车极限,不比速度,不求马力,争的反而是一个不甚性感的头衔:"全球省油冠军"。美国威斯康辛州麦迪逊市,一个夏季的周六,停车场里头有十来个人围着一辆红色本田Insight,看着韦恩做准备。他即将参加油电混合动力车MPG大挑战的开幕赛,赛车手将绕行市区36公里竞技。韦恩是赢面最大的车手,但这场比赛不同一般,旨在试探汽车极限,不比速度,不求马力

关键词：韦恩一辆本田引擎混合动力车刹车燃油效率冠军名次(运动竞赛)

Portlet应用开发实例——Pluto中添加新的Portal Page和Portlet

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程序员（CSDN开发高手） 2004年第4期 16-20页

作者： terry.lee

本部分使用基础配置篇中搭建的开发环境，如果还没有搭建好开发环境，请参考前文进行开发环境的搭建。

关键词：软件开发 Portlet Pluto Portal Page Portlet