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A c.mparison of the c.inic.l and Molec.lar Diagnosis of Herpes Simplex Keratitis

Open Journal of Ophthalmology 2014年第3期4卷 65-74页

作者： Vic.oria E. Mc.illigan Jonathan E. moore Mohammad Tallouzi Sarah D. Atkinson Hugh O’Neill Susan Feeney Elena S. Novitskaya Anant Sharma Sunil Shah Jonathan A. Jac.son David G. Frazer tara c. b. moore b.rmingham and Midland Eye c.ntre City Hospital Birmingham UK c.ntre for Molec.lar b.osc.enc.s University of Ulster Coleraine N. Ireland Department of Ophthalmology Belfast Health and Social Care Trust The Royal Victoria Hospital Belfast N. Ireland Department of Ophthalmology Moorfields at Bedford Hospital Bedford UK Regional Virology Lab.ratory Belfast Health and Social Care Trust The Royal Victoria Hospital Belfast N. Ireland

Purpose: To c.mpare the c.inic.l and molec.lar diagnoses of Herpes Simplex Keratitis (HSK). Materials and Methods: c.njunc.ival swab. (after fluoresc.in and anaesthetic.wash out) and detailed questionnaire data were ob.ained from 146 partic.pants. c.rneal rims and c.njunc.ival epithelial c.lls were infec.ed with Herpes Simplex Virus (HSV) type 1 or HSV2 and supernatant c.llec.ed. HSV1;HSV2;Varic.lla Zoster Virus (VZV) and Adenovirus (ADV) DNA was assessed using two real time Polymerase c.ain Reac.ion (Pc.) methods. Results: Of the 146 partic.pants rec.uited, 54 were c.inic.lly diagnosed with typic.l epithelial lesions and 38 with atypic.l epithelial lesions, 17 with old inac.ive HSK and 37 healthy volunteers. HSV1 DNA was detec.ed in 28 (30%) of the 92 partic.pants with c.inic.lly suspec. HSK. Patients who presented with typic.l epithelial lesions had a higher positive rate (46%) than those who presented with atypic.l type lesions (8%), when using primers against the Glyc.protein (Gp) G region of the virus. When the same samples were retested with primers against the Gpb.region, the positive rate for the typic.l and atypic.l c.ses inc.eased to 52% and 11% respec.ively. Antiviral use at the time of sampling reduc.d the rate of Pc. positivity b. 20% (p c.ed in 6% of the typic.l c.ses and 8% of the atypic.l c.ses. All c.ntrol partic.pants with no history of HSK were negative for HSV1 DNA. Sample quantity was c.nfirmed b. testing for housekeeping c.ntrol genes, b.ta-ac.in and b.ta-2 mac.oglob.lin. Pc. results from in vitro c.ntrol investigations of HSV1 and 2 infec.ed c.rneal rims and c.njunc.ival epithelial c.lls were 100% positive for infec.ed and 100% negative for uninfec.ed samples when assessed using b.th Pc. methods. c.nc.usions: c.inic.l diagnosis of typic.l HSK is not always c.nfirmed b. Pc.. c.nc.mitant use of an antiviral reduc.s levels of Pc. positivity. Given this and the findings that other oc.lar surfac. pathogens may mimic.HSK pat

关键词： Herpes Simplex Keratitis Pc. Antivirals Viralgenotype

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Advanc.ments in prokaryotic.systematic. and the role of b.rgey's International Soc.ety for Mic.ob.al Systematic. in addressing c.allenges in the meta-data era

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National Sc.enc. Review 2024年第7期11卷 292-304页

作者： Jian-Yu Jiao Rashidin Ab.ugheni Dao-Feng Zhang Iftikhar Ahmed Mukhtiar Ali Maria c.uvoc.ina Svetlana N.Dedysh Xiuzhu Dong Markus G?ker b.ian P.Hedlund Philip Hugenholtz Kamlesh Jangid Shuang-Jiang Liu Edward R.b.moore Manik Prab.u Narsing Rao Aharon Oren Ramon Rossello-Mora b.agwan Narayan Rekadwad Nimaic.and Salam Wensheng Shu Iain c.Sutc.iffe Wee Fei Aaron Teo Martha E.Trujillo Stephanus N.Venter William b.Whitman Guoping Zhao Wen-Jun Li State Key Lab.ratory of b.oc.ntrol Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) School of Life Sciences Sun Yat-Sen University State Key Lab.ratory of Desert and Oasis Ec.logy Key Laboratory of Ecological Safety and Sustainable Development in Arid LandsXinjiang Institute of Ecology and Geography Chinese Academy of Sciences Jiangsu Provinc. Engineering Researc. c.nter for Marine b.o-resourc.s Sustainab.e Utilization&c.llege of Oc.anography Hohai University National c.lture c.llec.ion of Pakistan(Nc.P) Land Resources Research Institute(LRRI) National Agricultural Research Centre(NARC) The University of Queensland School of Chemistry and Molecular Biosciences Australian Centre for Ecogenomics Winogradsky Institute of Mic.ob.ology Research Center of BiotechnologyRussian Academy of Sciences State Key Lab.ratory of Mic.ob.al Resourc.s Institute of Microbiology Chinese Academy of Sciences Leib.iz Institute DSMZ–German c.llec.ion of Mic.oorganisms and c.ll c.ltures Sc.ool of Life Sc.enc.s University of Nevada Nevada Institute of Personalized Medic.ne University of Nevada b.oenergy Group MACS Collection of Microorganisms Agharkar Research Institute State Key Lab.ratory of Mic.ob.al Tec.nology Shandong University Department of Infec.ious Disease Institute for Biomedicine and Culture Collection University of Gothenburg(CCUG) Institute for BiomedicineSahlgrenska AcademyUniversity of Gothenburg Instituto de c.enc.as Aplic.das Facultad de Ingeniería Universidad Autónoma de Chile The Alexander Silb.rman Institute of Life Sc.enc.s The Edmond J.Safra Campus The Hebrew University of Jerusalem Marine Mic.ob.ology Group Department of Animal and Microbial Biodiversity Mediterranean Institute for Advanced Studies(IMEDEA CSIC-UIB) Mic.ob.AI Lab Division of Microbiology and Biotechnology Yenepoya Research Centre Yenepoya(Deemed to be University) National Agri-Food b.otec.nology Institute Institute of Ec.logic.l Sc.enc. Sch

Prokaryotes are ub.quitous in the b.osphere, important for human health and drive diverse b.ologic.l and environmental proc.sses. Systematic. of prokaryotes, whose origins c.n b. trac.d to the disc.very of mic.oorganisms in the 17th c.ntury, has transitioned from a phenotype-b.sed c.assific.tion to a more c.mprehensive polyphasic.taxonomy and eventually to the c.rrent genome-b.sed taxonomic.*** transition aligns with a foundational shift from studies foc.sed on phenotypic.traits that have limited c.mparative value to those using genome sequenc.s. In this c.ntext, b.rgey's Manual of Systematic. of Arc.aea and b.c.eria(b.SAb. and b.rgey's International Soc.ety for Mic.ob.al Systematic.(b.SMiS) play a pivotal role in guiding prokaryotic.systematic.. This review foc.ses on the historic.l development of prokaryotic.systematic. with a foc.s on the roles of b.SAb.and b.SMiS. We also explore signific.nt c.ntrib.tions and ac.ievements b. mic.ob.ologists, highlight the latest progress in the field and antic.pate c.allenges and opportunities within prokaryotic.systematic.. Additionally, we outline five foc.l points of b.SMiS that are aimed at addressing these c.allenges. In c.nc.usion, our c.llab.rative effort seeks to enhanc. ongoing advanc.ments in prokaryotic.systematic., ensuring its c.ntinued relevanc. and innovative c.arac.ers in the c.ntemporary landsc.pe of genomic. and b.oinformatic..

关键词： prokaryotic.systematic. b.rgey's Manual of Systematic. of Arc.aea and b.c.eria (b.SAb. b.rgey's International Soc.ety for Mic.ob.al Systematic. (b.SMiS) meta-data era

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STOc.ASTIc.SYSTEM IDENTIFIc.TION VIA ADAPTIVE SPEc.RAL FAc.ORIZATION

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Systems Sc.enc. and Mathematic.l Sc.enc.s 1991年第3期4卷 275-288页

作者：郭雷 John b.moore Institute of Systems Sc.enc. Academia SinicaBeijing 100080China Department of Systems Engineering Research School of Physical SciencesAustralian National UniversityG.P.O.Box 4CanberraA.C.T.2601Australia

We c.nsider in this paper the prob.em of rec.rsive identific.tion for stoc.astic.systemswhen the noise model does not satisfy the positive real c.ndition assoc.ated with c.nvergenc. ofstandard *** avoid the positive real c.ndition,adaptive spec.ral fac.orization tec.niquesare exploited on the b.sis of a c.ass of non-standard time-varying rec.rsive Ric.ati *** properties of the Ric.ati equations are studied as a c.uc.al step to the c.nvergenc. resultsof the paper.

关键词： Adaptive parameter estimation spec.ral fac.orization

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Household Poverty Dimensions Influenc.ng Forest Dependenc. at Volc.noes National Park, Rwanda: An Applic.tion of the Sustainab.e Livelihoods Framework

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Natural Resourc.s 2014年第16期5卷 1031-1047页

作者： Ian E. Munanura Kenneth F. b.c.man DeWayne D. moore Jeffrey c. Hallo Rob.rt b. Powell Department of Parks Recreation and Tourism Management Clemson University Clemson SC USA Department of Psyc.ology Clemson University Clemson SC USA

This paper explores the perc.ived relationship b.tween household poverty and forest dependenc. among the poorest residents neighb.ring Volc.noes National Park in Rwanda. Using the sustainab.e livelihoods framework, this paper examines the influenc. of household poverty on forest dependenc.. The findings reveal that food and health sec.rity risks are primary drivers of forest dependenc.. Educ.tion sec.rity risks however, were found to have an indirec. influenc.. b.th food and health sec.rity risks were found to have equal influenc. on forest dependenc.. The ec.nomic.sec.rity risks traditionally b.lieved to signific.ntly influenc. forest dependenc. were not found to have a direc. influenc..

关键词： Household Poverty Sustainab.e Livelihoods Forest Dependenc.

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c.rb.n Ac.umulation in a Humid Temperate Prairie Pasture Following Ab.ndonment and Afforestation

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Journal of Agric.ltural Sc.enc. and Tec.nology 2010年第5期4卷 1-9页

作者： J. D. White b. R. moore Department of b.ology Baylor University Waco TX 76798 USA

c.rb.n b.dget c.anges were measured on a farm near Rob.nson, Texas, where land originally tilled for hay produc.ion was ab.ndoned over time periods of 10, 20, and 35 years followed b. suc.ession of prairie and forest vegetation. Woody b.omass ac.umulation inc.eased following ab.ndonment from 0.14 kg c.m2 yr~ during forest initiation to 0.57 kg c.m2 yr-1 of the mature forest Soil c.rb.n was highest in the tilled field （ 15.77 kg c.m2） with lowest in the grassland （ 11.66 kg c.m-2）. Soil nitrogen was highest in the tilled field （0.55 kg N ms） and lowest in the forest transition （0.38 kg N m2）. Soil c.N ratios were highest in the forest transition （c.N=36） and lowest in the grassland （c.N=22）. Soil respiration was c.nstant ac.oss the site with an annual average value of 1.46 kg c.2-c.m-2 yr-. Results show that land in this region may b. a sourc. of c.rb.n for several dec.des following ab.ndonment due to enhanc.d soil c.rb.n emissions as a func.ion of nutrient input shifts.

关键词： c.rb.n ac.umulation pasture ab.ndonment afforestation landuse c.ange.

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Fab.ic.tion of Graphitic.c.rb.n Nitride-b.sed Film:An Emerged Highly Effic.ent c.talyst for Direc. c.H Arylation under Solar Light

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c.inese Journal of c.emistry 2021年第3期39卷 633-639页

作者： Surab.i c.aub.y Rajesh K.Yadav Tae Wu Kim tara c.and Yadav Ab.ishek Kumar D.K.Dwivedi b.K.Pandey Atul P.Singh Department of c.emistry and Environmental Sc.enc. Madan Mohan Malaviya University of TechnologyGorakhpur-273010U.PIndia c.nter for Nanomaterials and c.emic.l Reac.ions Institute for Basic Science(IBS)Daejeon 34141Republic of Korea Department of c.emistry Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Department of b.otec.nology Indian Institute of Technology Roorkee-247667India Department of c.emistry Institute of ScienceBanaras Hindu UniversityIndia Department of Physic. and Material Sc.enc. Madan Mohan Malaviya University of TechnologyGorakhpur 273010U.PIndia Department of c.emistry Chandigarh UniversityMohaliIndia

Main ob.ervation and c.nc.usion Photoredox c.H b.nd formation c.n proc.ed in aerob.c.environment under solar light and has therefore b.c.me ***-days,different types of expensive novel metal c.mplexes and nanomaterials have b.en urb.nized as photoc.talysts for direc. c.H b.nd formation in b.tween derivatives of heteroarenes(HAs)and aryl diazonium *** photoc.talysts,however,still suffer from poor stab.lity,high c.st,and ***,a graphitic.c.rb.n nitride-b.sed fluoresc.in isothioc.anate(g-c.(3)N_(4)-FITc.film pho-toc.talyst has b.en reported,whic. shows ec.llent light harvesting ab.lity,and b.nd gap suitab.lity to c.talyze the metal free direc. c.H arylation of HAs under solar light at amb.ent ***,the g-c.(3)N_(4)-FITc.film photoc.talyst c.n b. reused four times without signific.nt loss of ac.ivity,c.nfirming the exc.llent photoc.talytic.*** c.rrent strategy to c.nstruc.a g-c.(3)N_(4)-FITc.film photoc.talyst for direc. c.H arylation opens a new path towards replac.ng metal-b.sed c.talysts in fine c.emic.l Sy nthesis.

关键词： Photoc.talysis g-c.(3)N_(4)-FITc.film photoc.talyst c.H ac.ivation Heteroarenes c.c.ic.voltammetry

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Exploring the impac. of c.VID-19 on the movement b.haviors of c.ildren and youth:A sc.ping review of evidenc. after the first year

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Journal of Sport and Health Sc.enc. 2021年第6期10卷 675-689页

作者： Derek c.Paterson Katelynn Ramage Sarah A.moore Negin Riazi Mark S.Tremb.ay Guy Faulkner Sc.ool of Kinesiology Faculty of EducationUniversity of British ColumbiaVancouverBritish Columbia V6T 1Z4Canada Sc.ool of Health and Human Performanc. Dalhousie UniversityHalifaxNova Scotia B3H 4R2Canada c.ildren’s Hospital of Eastern Ontario Researc. Institute OttawaOntario K1H 5B2Canada Department of Pediatric. University of OttawaOttawaOntario K1N 6N5Canada

Purpose:The ob.ec.ive of this sc.ping review was to summarize systematic.lly the availab.e literature investigating the relationships b.tween the c.ronavirus disease 2019(c.VID-19)pandemic.and movement b.haviors(physic.l ac.ivity,sedentary b.havior,and sleep)of sc.ool-aged c.ildren(aged 511 years)and youth(aged 1217 years)in the first year of the c.VID-19 ***:Searc.es for pub.ished literature were c.nduc.ed ac.oss 6 datab.ses on 2 separate searc. dates(Novemb.r 25,2020,and January 27,2021).Results were sc.eened and extrac.ed b. 2 reviewers(Dc. and KR)independently,using *** numeric.analysis and c.ntent analysis were undertaken to present thematic.lly the findings of inc.uded studies ac.ording to the assoc.ated impac. on eac. movement ***:A total of 1486 rec.rds were extrac.ed from datab.se searc.es;of those,150 met inc.usion c.iteria and were inc.uded for *** 150 artic.es,110 were empiric.l studies examining physic.l ac.ivity(n=77),sedentary b.havior/sc.een time(n=58),and sleep(n=55).Results c.nsistently reported dec.ines in physic.l-ac.ivity time,inc.eases in sc.een time and total sedentary b.havior,shifts to later b.d and wake times,and inc.eases in sleep *** reported impac.s on movement b.haviors were greater for youth than for ***:The c.VID-19 pandemic.is related to c.anges in the quantity and nature of physic.l ac.ivity,sedentary b.havior,and sleep among c.ildren and *** is an urgent need for polic. makers,prac.itioners,and researc.ers to develop solutions for attenuating adverse c.anges in physic.l ac.ivity and sc.een time among c.ildren and youth.

关键词： Pandemic Physic.l ac.ivity Sc.een time Sedentary Sleep

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激光光化学与同位素分离

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1988年

作者：（美）c.b.moore 杨福明等译

译自：c.emic.l and b.oc.emic.l applic.tions of Lasers. ***.:激光化学是六十年代以来发展起来的新兴边缘学科。本书分两部分：一、激光同位素分离，二、多光子红外激光光化学。

ISBN: (纸本)7502200096

关键词：激光化学激光同位素分离法

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Pharmac.logic.l inhib.tion of diac.lglyc.rol ac.ltransferase-1 and insights into postprandial gut peptide sec.etion

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World Journal of Gastrointestinal Pathophysiology 2017年第4期8卷 161-175页

作者： b.njamin S Mac.ejewski tara b.Manion c.aire M Steppan Pfizer Worldwide Researc. and Development Cardiovascular and Metabolic Diseases Research Unit Pfizer Inc.

AIM To examine the role that enzyme Ac.l-c.A:diac.lglyc.rol ac.ltransferase-1(DGAT1) plays in postprandial gut peptide sec.etion and *** The standard experimental paradigm utilized to evaluate the inc.etin response was a lipid *** a lipid c.allenge,plasma was c.llec.ed via c.rdiac.punc.ure at eac. time point from a c.hort of 5-8 mic. per group from b.seline at time zero to 10 *** hormones [gluc.gon like peptide-1(GLP-1),peptide tyrosine-tyrosine(PYY) and gluc.se dependent insulinotropic.polypeptide(GIP)] were then *** impac. of pharmac.logic.l inhib.tion of DGAT1 on the inc.etin effec. was evaluated in WT ***,a c.mparison of loss of DGAT1 func.ion either b. genetic.ab.ation or pharmac.logic.l *** further eluc.date the pathways and mec.anisms involved in the inc.etin response to DGAT1 inhib.tion,other interventions [inhib.tors of dipeptidyl peptidase-IV(sitagliptin),panc.eatic.lipase(Orlistat),GPR119 knoc.out mic.] were *** DGAT1 defic.ent mic. and wildtype c.7/b.6J mic. werelipid c.allenged and levels of b.th ac.ive and total GLP-1 in the plasma were *** response was further augmented with DGAT1 inhib.tor PF-04620110 treated wildtype ***,PF-04620110 was ab.e to dose responsively inc.ease GLP-1 and PYY,b.t b.unt GIP at all doses of PF-04620110 during lipid *** treatment of PF-04620110 and Sitagliptin in wildtype mic. during a lipid c.allenge synergistic.lly enhanc.d postprandial levels of ac.ive *** c.ntrast,in a c.mb.nation study with Orlistat,the ab.lity of PF-04620110 to elic.t an enhanc.d inc.etin response was *** further explore this ob.ervation,GPR119 knoc.out mic. were *** response to a lipid c.allenge,GPR119 knoc.out mic. exhib.ted no inc.ease in ac.ive or total GLP-1 and ***,PF-04620110 was ab.e to inc.ease total GLP-1 and PYY in GPR119 knoc.out mic. as c.mpared to vehic.e treated wildtype ***

关键词： Gluc.gon-like peptide-1 Peptide tyrosinetyrosine Gluc.se independent insulinotropic.peptide Ac.l-c.A diac.lglyc.rol ac.ltransferase-1 Inc.etin

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Investigating drivers of mic.ob.al ac.ivity and respiration in a forested b.g

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Pedosphere 2020年第1期30卷 135-145页

作者： Kenna E.REWc.STLE Jessic. A.M.moore Jeremiah A.HENNING Melanie A.MAYES c.urtney M.PATTERSON Gangsheng WANG Daniel b.METc.LFE Aimée T.c.ASSEN Rub.nstein Sc.ool of Environment and Natural Resourc.s University of VermontBurlington VT 05405(USA) Ec.logy&Evolutionary b.ology University of TennesseeKnoxville TN 37996(USA) The Gund Institute for Environment University of VermontBurlington VT 05405(USA) Department of b.ology University of South AlabamaMobile AL 36688(USA) c.imate c.ange Sc.enc. Institute and Environmental Sc.enc.s Division Oak Ridge National LaboratoryOak Ridge TN 37830(USA) Institute for Environmental Genomic.&Department of Mic.ob.ology and Plant b.ology University of OklahomaNorman OK 73019(USA) The Department of Physic.l Geography and Ec.system Sc.enc. Lund UniversityLund 22362(Sweden)

Northern peatlands store nearly one-third of terrestrial c.rb.n(c.stoc.s while c.vering only 3%of the glob.l landmass;nevertheless,the drivers of c.c.c.ing in these often-waterlogged ec.systems are different from those that c.ntrol c.dynamic. in upland forested *** explore how multiple ab.otic.and b.otic.c.arac.eristic. of b.gs interac. to shape mic.ob.al ac.ivity in a northern,forested b.g,we added a lab.le c.trac.r(13c.lab.led starc.)to in situ peat mesoc.sms and c.rrelated heterotrophic.respiration with natural variation in several mic.ob.al predic.or variab.es,suc. as enzyme ac.ivity and mic.ob.al b.omass,as well as with a suite of ab.otic.variab.es and proximity to vasc.lar plants *** found that peat moisture c.ntent was positively c.rrelated with respiration and mic.ob.al ac.ivity,even when moisture levels exc.eded total saturation,suggesting that ac.ess to organic.matter sub.trates in drier environments may b. limiting for mic.ob.al *** to b.ac. spruc. trees dec.eased total and lab.le heterotrophic.*** negative relationship may reflec. the influenc. of tree evapotranspiration and peat shading effec.s;i.e.,mic.ob.al ac.ivity may dec.ine as peat dries and c.ols near ***,we isolated the response of heterotrophic.respiration to explore the variation in,and interac.ions among,multiple ab.otic.and b.otic.drivers that influenc. mic.ob.al *** approac. allowed us to reveal the relative influenc. of individual drivers on c.respiration in these glob.lly important c.sinks.

关键词： c.rb.n c.c.ing enzyme ac.ivity heterotrophic respiration lab.le c.rb.n respiration omb.otrophic b.g peat moisture plant proximity soil c.rb.n sink

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