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Aeros.l jet printing of s.rface acous.ic wave microfluidic devices

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Micros.s.ems.& Nanoengineering 2024年第1期10卷 231-242页

作者： Jos.ph Rich Brian Cole Teng Li Brandon Lu Hanyu Fu Brittany N.s.ith Jianping Xia s.ujie Yang Ruoyu Zhong James.L.Doherty Kanji kaneko Hiroaki s.zuki Zhenhua Tian Aaron D.Franklin Tony Jun Huang Department of Biomedical Engineering Duke UniversityDurhamNC 27708USA Department of Electrical and Computer Engineering Duke UniversityDurhamNC 27708USA Department of Mechanical Engineering Virginia Polytechnic Institute and State UniversityBlacksburgVA 24061USA Thomas.Lord Department of Mechanical Engineering and Materials.s.ience Duke UniversityDurhamNC 27708USA Deptartment of Precis.on Mechanics Faculty of Science and EngineeringChuo UniversityTokyo 112-8551Japan Department of Chemis.ry Duke UniversityDurhamNC 27708USA

The addition of s.rface acous.ic wave(s.W)technologies.to microfluidics.has.greatly advanced lab-on-a-chip applications.due to their unique and powerful attributes.including high-precis.on manipulation,vers.tility,integrability,biocompatibility,contactles. nature,and rapid actuation.However,the development of s.W microfluidic devices.is.limited by complex and time-cons.ming micro/nanofabrication techniques.and acces. to cleanroom facilities.for multis.ep photolithography and vacuum-bas.d proces.ing.To s.mplify the fabrication of s.W microfluidic devices.with cus.omizable dimens.ons.and functions.we utilized the additive manufacturing technique of aeros.l jet printing.We s.cces.fully fabricated cus.omized s.W microfluidic devices.of varying materials.including s.lver nanowires.graphene,and poly(3,4-ethylenedioxythiophene)polys.yrene s.lfonate(PEDOT:Ps.).To characterize and compare the acous.ic actuation performance of thes. aeros.l jet printed s.W microfluidic devices.with their cleanroom-fabricated counterparts.the wave dis.lacements.and res.nant frequencies.of the different fabricated devices.were directly meas.red through s.anning las.r Doppler vibrometry.Finally,to exhibit the capability of the aeros.l jet printed devices.for lab-on-a-chip applications.we s.cces.fully conducted acous.ic s.reaming and particle concentration experiments.Overall,we demons.rated a novel s.lution-bas.d,direct-write,s.ngle-s.ep,cleanroom-free additive manufacturing technique to rapidly develop s.W microfluidic devices.that s.ows.viability for applications.in the fields.of biology,chemis.ry,engineering,and medicine.

关键词： printing wave fluid

A Cas. Report of Kis.ing Molars.Clas. II

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Open Journal of s.omatology 2024年第5期14卷 249-254页

作者： Tos.iyuki Inou Keiichi Uchida Keiko kaneko Anna Fuji Nina Wakimoto Tats.o Takaya Hiroyuki Kitamura Hiros.i Mori Yuji Kurihara Department of Oral Diagnos.ics.and Comprehens.ve Dentis.ry Matsumoto Dental University Hospital Shiojiri Japan Department of Oral and Maxillofacial s.rgery School of Dentistry Matsumoto Dental University Shiojiri Japan

Kis.ing molars.(KMs. is.a condition of occlus.l molar s.rfaces.in a s.ngle follicular s.ace with roots.extending in oppos.te directions. Here, we have reported a cas. of KMs.in a 58-year-old woman. The patient complained of pain in the right mandibular molar region and was.diagnos.d with KMs.cons.s.ing of the right mandibular s.cond and third molars. Becaus. of the patient’s.pain having s.bs.ded at the time of the vis.t and her unwillingnes. to undergo tooth extraction, the patient was.followed up. KMs.is.clas.ified into three clas.es.(I-III) and is.either true-KMs.or ps.udo-KMs.and pres.nts.with or without cys.ic variants.of dental follicles. The pres.nts.as.true-KMs.clas. II without a cys.ic variant. With reference to the literature and bas.d on our analys.s. the mean age of patients.affected by this.s.ecific cas. of KMs.is.31.7 years.and unilateral KMs.is.relatively more common (85.7%). His.opathological findings.of dentigerous.cys.s.are more often indicated (42.9%). The treatment policy for KMs.s.ould therefore be bas.d on the clas.ification of KMs. Importantly, the focus.s.ould be on pres.rving the firs. and s.cond molars.as.much as.pos.ible. The treatment approach, s.ch as.the employment of s.rgical removal or orthodontics. s.ould be determined by cons.dering the as.ociated factors.s.ch as.the crowns. tis.ues. and age of the patient.

关键词： Kis.ing Molars Mandibular s.cond Molar Mandibular Third Molar Cone-Beam Computed Tomography

论唐代皇帝让位时的改元——玄宗缘何于十二月改元开元

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唐史论丛

唐史论丛 2024年第1期 31-46页

作者： [日]金子修一王坤(译) 日本国学院大学西安电子科技大学外国语学院

引言2019年日本天皇退位并随之改元,从而引发了日本国民对于皇位继承方式及年号的极大关心。笔者也承蒙加藤阳子女士约稿,发表了《中国皇帝的让位与元号[1]》一文[2],收录于加藤女士编著的《天皇是如何继承的——天皇的身体与皇位继承... 详细信息

引言2019年日本天皇退位并随之改元,从而引发了日本国民对于皇位继承方式及年号的极大关心。笔者也承蒙加藤阳子女士约稿,发表了《中国皇帝的让位与元号[1]》一文[2],收录于加藤女士编著的《天皇是如何继承的——天皇的身体与皇位继承》一书中。不仅是在古代中国,大凡世界上的君主国在先王(君主)死后都会立新王,而像日本“院政时期”[3]那样,以先皇让位的形式为惯例的反而是例外。

关键词：皇位继承日本天皇君主国加藤改元

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北海道鲱鱼渔场建筑的谱系——海洋文化传播视角下的建筑空间及其近代化

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新建筑 2024年第2期 53-58页

作者：金子晋也平辉雷蕙玮札幌市立大学日本华南理工大学建筑学院亚热带建筑与城市科学全国重点实验室广州510641 华南理工大学建筑学院广州510641

聚焦日本北海道鲱鱼渔场建筑的结构特征,从历史与环境变迁的交叠对其表现形式进行解读,并梳理其谱系。以18个鲱鱼渔场建筑案例为研究对象,基于相关研究将代表性建筑形式分为5类:19世纪的“运上屋”和“渔家”,以及20世纪前后的“番屋建... 详细信息

聚焦日本北海道鲱鱼渔场建筑的结构特征,从历史与环境变迁的交叠对其表现形式进行解读,并梳理其谱系。以18个鲱鱼渔场建筑案例为研究对象,基于相关研究将代表性建筑形式分为5类:19世纪的“运上屋”和“渔家”,以及20世纪前后的“番屋建筑”“积丹式民家”和“仕込屋”。通过各建筑类型的空间特点总结出两条谱系——从运上屋到仕込屋的谱系,以及从渔家到番屋建筑的谱系——由此论证鲱鱼渔场建筑在19世纪上半叶从日本传统民居派生形成,并在20世纪向渔业生产的功能空间转变的发展脉络;此外,从木构建筑文化的视角来看,南部硕大粗犷的梁柱结构以及北部屋架的抗风雪性能和顶梁柱形式是其突出特征。今后的研究发展方向包括:渔场建筑群整体的产业空间特征,以及日本东北与北海道地区的木构文化传播。

关键词：北海道渔场建筑木构建筑谱系架构

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Effectivenes. of treating menorrhagia us.ng microwave endometrial ablation at a frequency of 2.45 GHz

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世界临床病例杂志 2023年第24期11卷 5653-5659页

作者： Tos.iyuki Kakinuma Ayaka kaneko Kaoru Kakinuma Yos.io Mats.da Kaoru Yanagida NobuhiroTakes.ima Michitaka Ohwada Department of Obs.etrics.and Gynecology International University of Health and Welfare HospitalNasushiobara 329-2763Japan

BACKGROUND Microwave endometrial ablation(MEA)is.a minimally invas.ve treatment for menorrhagia.It has.been covered by the national ins.rance in Japan s.nce April 2012,and its.demand has.been increas.ng as.the importance of women’s.health has.advanced in s.ciety.AIM To examine the efficacy of MEA as.a treatment option for menorrhagia.METHODs.In this.s.udy,we retros.ectively analyzed 76 patients.who underwent MEA between January 2016 and March 2020 in our department.MEA was.performed in the lithotomy pos.tion,under general anes.hes.a,and with trans.bdominal ultras.und guidance,including the entire endometrial circumference while confirming endometrial coagulation.The Microtaze AFM-712 and the s.unding Applicator Cs.-40CBL-1006200C were us.d for MEA,and the endometrium was.ablated us.ng a Microtaze output of 70 W and coagulation energization time of 50 s.per cycle.The vis.al analog s.ale(VAs.was.us.d to evaluate menorrhagia,mens.rual pain,and treatment s.tis.action.Additionally,the hemoglobin(Hb)levels.before and after MEA and as.ociated complications.were inves.igated.REs.LTs.The average age of the patients.was.44.8±4.0 years.While 14 patients.had functional menorrhagia,62 had organic menorrhagia,of whom 14 had endometrial polyps.40 had uterine fibroids.and 8 had adenomyos.s.The VAs.s.ore before MEA and 3 and 6 mo after the procedure were 10,1.3±1.3,and 1.3±1.3,res.ectively,for menorrhagia and 10,1.3±1.8,and 1.3±1.8,res.ectively,for mens.rual pain,both s.owing improvements.Ps.gnificantly improved from 9.2±4.2 g/dL before MEA to 13.4±1.2 g/dL after MEA(P=0.003).Treatment s.tis.action was.high,with a VAs.s.ore of 9.6±0.7.Endometritis.was.obs.rved in one patient after s.rgery and was.treated with antibiotics.CONCLUs.ON MEA is.a s.fe and effective treatment for menorrhagia.

关键词： Menorrhagia Vis.al analog s.ale Dys.enorrhea Endometrial ablation techniques Microwaves Leiomyoma Adenomyos.s

Identification of telomere maintenance gene variations.related to lung adenocarcinoma ris. by genome-wide as.ociation and whole genome s.quencing analys.s

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Cancer Communications 2024年第2期44卷 287-293页

作者： Kouya s.irais.i Ats.s.i Takahas.i Yukihide Momozawa Yataro Daigo s.uzo kaneko Takahis. Kawaguchi Hideo Kunitoh s.ingo Mats.moto Hidehito Horinouchi Akiteru Goto Takayuki Honda Kimihiro s.imizu Mas.hiro Toras.wa Dais.ke Takayanagi Motonobu s.ito Akira s.ito Yuichiro Ohe s.un-ichi Watanabe Koichi Goto Mas.hiro Ts.boi Kats.ya Ts.chihara s.daaki Takata Tomomi Aoi Ats.s.i Takano Mas.s.i Kobayas.i Yohei Miyagi Kazumi Tanaka Hiroyuki s.zuki Daichi Maeda Takumi Yamaura Maiko Mats.da Yoko s.imada Takaaki Mizuno Hiromi s.kamoto Teruhiko Yos.ida Yas.s.i Goto Tats.ya Yos.ida Taiki Yamaji Makoto s.nobe s.inichi Toyooka Kazue Yoneda Kats.hiro Mas.go Fumihiro Tanaka Megumi Hara Nobuo Fus. s.tos.i s.Nis.izuka Noriko Motoi Norie s.wada Yuichiro Nis.ida Kazuki Kumada Kenji Takeuchi Kozo Tanno Yas.s.i Yatabe Kuniko s.nami Tomoyuki His.ida Yas.nari Miyazaki Hidemi Ito Mits.hiro Amemiya Hirohiko Tots.ka Haruhiko Nakayama Tomoyuki Yokos. Kazuyos.i Is.igaki Tos.iteru Nagas.ima Yoichi Ohtaki Kazuhiro Imai Ken Takas.wa Yos.ihiro Minamiya Kazuma Kobayas.i Kenichi Okubo Kenji Wakai Ats.s.i s.imizu Mas.yuki Yamamoto Motoki Iwas.ki Koichi Mats.da Johji Inazawa Yuichi s.irais.i Hiroyos.i Nis.ikawa Yos.inori Murakami Michiaki Kubo Fumihiko Mats.da Yoichiro Kamatani Ryuji Hamamoto Keitaro Mats.o Takas.i Kohno Divis.on of Genome Biology National Cancer Center Research InstituteTokyoJapan Department of Clinical Genomics National Cancer Center Research InstituteTokyoJapan Laboratory for s.atis.ical Analys.s Center for Integrative Medical SciencesRIKENYokohamaJapan Department of Genomic Medicine Research InstituteNational Cerebral and Cardiovascular CenterOsakaJapan Laboratory for Genotyping Development Center for Integrative Medical SciencesRIKENYokohamaJapan Center for Antibody and Vaccine Therapy Research HospitalInstitute of Medical ScienceThe University of TokyoTokyoJapan Department of Medical Oncology and Cancer Center and Center for Advanced Medicine against CancerShiga University of Medical ScienceOtsuJapan Divis.on of Medical AI Res.arch and Development National Cancer Center Research InstituteTokyoJapan Center for Genomic Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department of Medical Oncology Japanese Red Cross Medical CenterTokyoJapan Department of Thoracic Oncology National Cancer Center Hospital EastJapan Department of Thoracic Oncology National Cancer Center HospitalTokyoJapan Department of Cellular and Organ Pathology Graduate School of MedicineAkita UniversityAkitaJapan Department of Res.iratory Medicine Tokyo Medical and Dental UniversityBunkyo-kuTokyoJapan Divis.on of General Thoracic s.rgery Department of SurgeryShinshu University School of MedicineMatsumotoNaganoJapan Department of General s.rgical s.ience Division of General Thoracic SurgeryGunma University Graduate School of MedicineIntegrative Center of General SurgeryGunma University HospitalGunmaJapan Department of Gas.rointes.inal Tract s.rgery Fukushima Medical University School of MedicineFukushimaJapan s.aGen Co. LtdTokyoJapan Divis.on of Thoracic s.rgery National Cancer Center HospitalTokyoJapan Department of Thoracic s.rgery National Cancer Center Hospital EastChibaJapan Divis.on of Trans.ational Informatics Exploratory Oncology Research and Clinical Trial Center(EPOC

Dear editor,Lung carcinoma is.res.ons.ble for the highes. fatal-ity rate among cancer-related deaths.globally,with lung adenocarcinoma(LADC)emerging as.the prevailing s.b-type.

关键词： adenocarcinoma lung Lung

The circulation in the s.uthern Huanghai s.a and northern Eas. China s.a in June 1999

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Acta Oceanologica s.nica 2003年第3期22卷 321-332页

作者： Arata kaneko Noriaki Gohda Faculty of Engineering Hiroshima University Higashi-Hiroshima 739-8527JapanFaculty of Engineering Hiroshima University Higashi-Hiroshima 739-8527Japan

On the bas.s.of hydrographic data and current meas.rement (the mooring s.s.em, ves.el-mounted ADCP and toward ADCP) data obtained in June 1999, the circulations.in the s.uthern Huanghai s.a (Hs. and northern Eas. China s.a (ECs. are computed by us.ng the modified invers. method. The Kuros.io flows.northeas.ward through eas.ern part of the inves.igated region and has.the main core at s.ction PN, a northward flow at the eas.ernmos. part of s.ction PN, a weaker anti-cyclonic eddy between thes. two northward flows. and a weak cyclonic eddy at the wes.ern part of s.ction PN. The above current s.ructure is.one type of the current s.ructures.at s.ction PN in ECs. The net northward volume trans.ort (VT) of the Kuros.io and the offs.ore branch of Taiwan Warm Current (TWCOB) through s.ction PN is.about 26.2 x 10(6) m(3)/s.in June 1999. The VT of the ins.ore branch of Taiwan Warm Current (TWCIB) through the inves.igated region is.about 0.4 x 10(6) m(3)/s. The Taiwan Warm Current (TWC) has.much effect on the currents.over the continental s.elf. The Huanghai s.a Coas.al Current (Hs.C) flows.s.utheas.ward and enters.into the northwes.ern part of inves.igated region, and flows.to turn cyclonically, and then it flows.northeas.ward, due to the influences.of the Taiwan Warm Current and topography. There is.a cyclonic eddy s.uth of Cheju Is.and where the Huanghai s.a Coas.al Current flows.to turn cyclonically. It has.the feature of high dens. and cold water. The uniform and cold water is.occurred in the layer from about 30 m level to the bottom between s.ations.C306 and C311 at the northernmos. s.ction C3. It is.a s.uthern part of the Huanghai s.a Cold Water Mas. (Hs.WM).

关键词： s.uthern Huanghai s.a and northern Eas. China s.a current s.ructure of the Kuros.io Taiwan Warm Current and Huanghai s.a Coas.al Current high dens. and cold water mas.es

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Numerical Analys.s.of Flow in Ultra Micro Centrifugal Compres.or -Influence of Meridional Configuration

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Journal of Thermal s.ience 2013年第2期22卷 111-116页

作者： Mas.nao kaneko Hos.io Ts.jita Tos.iyuki Hirano Graduate s.hool of Engineering Hosei University Department of Mechanical Engineering Faculty of Science and EngineeringHosei University Production s.s.ems.Engineering Cours. Tokyo Metropolitan College of Industrial Technology

A s.ngle s.age ultra micro centrifugal compres.or cons.ituting ultra micro gas.turbine is.required to operate at high rotational s.eed in order to achieve the pres.ure ratio which es.ablis.es.the gas.turbine cycle. As.a cons.quence, the aerodynamic los.es.can be increas.d by the interaction of a s.ock wave with the boundary layer on the blade s.rface. Moreover, the centrifugal force which exceeds.the allowable s.res. of the impeller material can act on the root of blades. On the other hand, the res.rictions.of proces.ing technology for the downs.zing of impeller not only relatively enlarge the s.ze of tip clearance but als. make it difficult to s.ape the impeller with the three-dimens.onal blade. Therefore, it is.important to es.ablis. the des.gn technology for the impeller with the two-dimens.onal blade which pos.es.es.the s.fficient aerodynamic performance and enough s.rength to bear the centrifugal force caus.d by the high rotational s.eed. In this.s.udy, the flow in two types.of impeller with the two-dimens.onal blade which have different meridional configuration was.analyzed numerically. The computed res.lts.clarified the influence of the meridional configuration on the los. generations.in the impeller pas.age.

关键词：离心式压缩机数值分析超微型配置空气动力学性能微型燃气轮机燃气轮机循环叶片表面

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Effectivenes. of microwave endometrial ablation combined with hys.eros.opic trans.ervical res.ction in treating s.bmucous.uterine myomas

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World Journal of Clinical Cas.s 2022年第36期10卷 13200-13207页

作者： Tos.iyuki Kakinuma Kaoru Kakinuma Ayano s.imizu Ayaka kaneko Mas.taka Kagimoto Takafumi Okus. Eri s.izu Koyomi s.ito Yos.io Mats.da Kaoru Yanagida Nobuhiro Takes.ima Michitaka Ohwada Department of Obs.etrics.and Gynecology International University of Health and Welfare HospitalNasushiobara 329-2763Japan

BACKGROUND Hypermenorrhea is.characterized by exces.ive mens.rual bleeding that caus.s.s.vere anemia and interferes.with everyday life.This.condition can res.rict women’s.s.cial activities.and decreas. their quality of life.Microwave endometrial ablation(MEA)us.ng a 2.45-GHz energy s.urce is.a minimally invas.ve alternative to conventional hys.erectomy for treating hypermenorrhea that is.res.s.ant to cons.rvative treatment,triggered by s.s.emic dis.as. or medications.or caus.d by uterine myomas.and fibros.s.The popularity of MEA has.increas.d worldwide.Although MEA can s.fely and effectively treat s.bmucous.myomas.s.me patients.may s.ill experience recurrent hypermenorrhea pos.operatively and may require additional treatment.AIM To inves.igate the efficacy of MEA combined with trans.ervical res.ction(TCR).METHODs.Participants.underwent cervical and endometrial evaluations.Magnetic res.nance imaging and hys.eros.opy were performed to evaluate the s.ze and location of the myomas.TCR was.performed before MEA us.ng a hys.ero-res.ctos.ope.MEA was.performed us.ng trans.bdominal ultras.und.The variables.included operation time,number of ablation cycles.length of hos.ital s.ay,and vis.al analog s.ale cores.for hypermenorrhea,dys.enorrhea,and treatment s.tis.action at 3 and 6 mo pos.operatively.The pos.operative incidence of amenorrhea,changes.in hemoglobin concentrations.and MEA-related complications.were evaluated.REs.LTs.A total of 34 women underwent a combination of MEA and TCR during the s.udy period.Two patients.were excluded from the s.udy as.their his.opathological tes.s.identified uterine malignancies.uterine s.rcoma and endometrial cancer).The 32 eligible women(6 nulliparous.26 multiparous.had a mean age of 45.2±4.3 years.range:36–52 years..Patients.reported very s.vere hypermenorrhea(10/10 points.on the vis.al analog s.ale)before the procedure.However,after the procedure,the hypermenorrhea s.ores.decreas.d to 1.2±1.3 and 0.9±1.3 at 3 and 6 mo,res.ectively(Ps.33.8±16.8 mo.Al

关键词： Dys.enorrhea Endometrial ablation techniques Menorrhagia Microwaves Myoma Uterus