检索结果-南通市图书馆

Bilateral cerebral infarction in diabetic ketoacidosis and bilateral internal carotid artery occlusion:A case report and review of literature

引用

World Journal of Clinical Cases 2021年第15期9卷 3787-3795页

作者： Yi-Chung Chen su-ju tsai Department of Physical Medicine and Rehabilitation Chung Shan Medical University HospitalTaichung 40201Taiwan

BACKGROUND Diabetic ketoacidosis(DKA)is a serious complication of type 1 diabetes mellitus(T1DM).Very rarely does DKA lead to cerebral edema,and it is even rarer for it to result in cerebral *** internal carotid artery occlusion(BICAO)is also rare and can cause fatal ***,case reports about acute cerebral infarction throughout both internal carotid arteries with simultaneous BICAO are very *** this study,we present a patient with BICAO,T1DM,hypertension,and hyperlipidemia,who had a catastrophic bilateral cerebral infarction after a DKA *** briefly introduce BICAO and the mechanisms by which DKA results in cerebral *** suMMARY A 41-year-old woman presented with ischemic stroke that took place 3 mo prior over the left corona radiata,bilateral frontal lobe,and parietal lobe with right hemiplegia and Broca’s *** had a history of hypertension for 5 years,hyperlipidemia for 4 years,hyperthyroidism for 3 years,and T1DM for 31 *** first brain magnetic resonance imaging not only revealed the aforementioned ischemic lesions but also bilateral internal carotid artery *** was admitted to our ward for rehabilitation due to prior stroke *** took place on hospital day *** hospital day 6,she had a new massive infarction over the bilateral anterior cerebral artery and middle cerebral artery *** weeks of aggressive treatment,she remained in a coma and on mechanical ventilation due to respiratory *** discussion with her family,compassionate extubation was performed on hospital day 29 and she *** DKA can lead to cerebral infarction due to several *** people with existing BICAO and several stroke risk factors such as hypertension, T1DM,hyperlipidemia, DKA has the potential to cause more serious ischemic strokes.

关键词： Type 1 diabetes mellitus Diabetic ketoacidosis Bilateral internal carotid artery occlusion Cerebral infarction Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Seismic response and correlation analysis of a pile-supported wharf to near-fault pulse-like ground motions

引用

Earthquake Engineering and Engineering Vibration 2024年第4期23卷 883-897页

作者： Wang Jianfeng su Lei Xie Libo Ling Xianzhang ju Peng School of Civil Engineering Qingdao University of TechnologyQingdao 266500China School of Civil Engineering Harbin Institute of TechnologyHarbin 150006China No.2 Engineering Company Ltd.of CCCC First Harbor Engineering Company Ltd Qingdao 266071China

Earthquake investigations have shown that near-fault pulse-like(NF-P)ground motions have unique characteristics compared to near-fault non-pulse-like(NF-NP)and far-field(FF)ground *** is necessary to study the seismic response of pile-supported wharf(PSW)structures under NF-P ground *** this study,a three-dimensional finite element numerical model is created to simulate a *** imparting three types of ground motion,the engineering demand parameters(EDPs)of PSW under NF-P ground motions were analyzed and compared,in which EDPs are the maximum displacement and bending moment of the *** intensity measures(IMs)were selected to characterize the properties of ground *** correlation between IMs and EDPs was *** results show that the piles present larger displacement and bending moment under NF-P ground motions compared to NF-NP and FF ground *** of the IMs have a high correlation with EDPs under NF-P ground motions,and these IMs are more applicable to FF ground *** correlation coefficients between EDPs and IMs under three types of ground motion were obtained,which will provide a valuable reference for the seismic design of PSWs.

关键词： pile-supported wharf correlation analysis near-fault pulse-like ground motion intensity measure seismic response

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

dECM restores macrophage immune homeostasis and alleviates iron overload to promote DTPI healing

引用

Regenerative Biomaterials 2024年第2期3卷 100-113页

作者： ju Zhang Ruijuan Si Yu Gao Hui Shan Qi su Zujian Feng Pingsheng Huang Deling Kong Weiwei Wang Tianjin Key Laboratory of Biomaterial Research Institute of Biomedical EngineeringChinese Academy of Medical Sciences and Peking Union Medical CollegeTianjin300192China School of Nursing Qingdao UniversityNingde RoadShinan DistrictQingdaoShandong266071China Cancer Hospital of Tianjin Medical University North Huanhu West RoadTianjinChina The Affliated Hospital of Qingdao University 16 Jjiangsu RoadShinan DistrictQingdaoChina 5NankaiUniver aniin300071.China

Due to its highly insidious and rapid progression,deep tissue pressure injury(DTPI)is a clinical *** previous study found that DTPI may be a skeletal muscle injury dominated by macrophage immune dysfunction due to excessive iron *** extracellular matrix(dECM)hydrogel promotes skeletal muscle injury ***,its role in po-larizing macrophages and regulating iron metabolism in DTPI remains ***,porcine dECM hydrogel was prepared,and its therapeutic function and mechanism in repairing DTPI were *** stimulus of dECM hydrogel toward RAW264.7 cells resulted in a significantly higher percentage of CD2o6+macrophages and notably decreased intracellular divalent iron *** mice DTPI model,dECM hydrogel treatment promoted M1 to M2 macrophage conversion,improved iron metabolism and reduced oxidative stress in the early stage of *** the remodeling phase,the dECM hydrogel remarkably enhanced revascularization and accelerated skeletal muscle ***,the immunomodulation of dEcM hydrogels in vivo was mainly involved in the P13k/Akt signaling pathway,as revealed by GO and KEGG pathway analysis,which may ameliorate the iron deposition and promote the healing of *** findings indicate that dECM hydrogel is promising in skeletal muscle repair,inflammation resolution and tissue injury healing by effectively restoring macrophage immune homeostasis and normalizing iron metabolism.

关键词： Deep tissue pressure injury hydrogel immunomodulation tissue repair

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A bacterial protein Rhp-PSP inhibits plant viral proliferation through endoribonuclease activity

引用

Journal of Integrative Agriculture 2024年第6期23卷 1967-1978页

作者： Lijie Chen Qianze Peng Xiaohua Du Weixing Zhang ju’e Cheng Shu’e sun Deyong Zhang Pin su Yong Liu Longping Branch College of BiologyHunan UniversityChangsha 410082China State Key Laboratory of Hybrid Rice/Institute of Plant Protection Hunan Academy of Agricultural SciencesChangsha 410125China

Plant virus causes massive crop losses ***,there is currently no effective measure to control plant viral ***,we identify an antiviral protein Rhp-PSP,produced by the bacterial Rhodopseudomonas palustris strain *** this study,we discover that the antiviral activity of Rhp-PSP relies on its endoribonuclease *** the arginine(R)residue at position 129 onto alanine(A)abolishs its endoribonuclease activity on coat protein(CP)RNA of tobacco mosaic virus(TMV),consequentially,compromises the antiviral activity of *** investigation demonstrates that,the mutant Rhp-PSP^(R129A)is unable to form the homotrimer as the wild type,indicating the importance of quaternary junction for the endoribonuclease *** of Rhp-PSP in Nicotiana benthamiana significantly enhances the resistance against TMV of seedlings,while expression of Rhp-PSP^(R129A)did not,confirming that endoribonuclease activity is responsible for the antiviral activity of *** addition,foliar spray of Rhp-PSP solution on tomato and pepper plants significantly reduces the disease index of viral diseases,indicating that Rhp-PSP shows potential to develop antiviral agent in practice.

关键词： Rhodopseudomonas palustris Rhp-PSP tobacco mosaic virus endoribonuclease antiviral activity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Metabolic relationships between marine red algae and algae‑associated bacteria

引用

Marine Life Science & Technology 2024年第2期6卷 298-314页

作者： Kyung Hyun Kim Jeong Min Kim ju Hye Baek Sang Eun Jeong Hocheol Kim Hwan su Yoon Che Ok Jeon Department of Biological Sciences and Biotechnology Hannam UniversityDaejon 34054Republic of Korea Department of Life Science Chung-Ang UniversitySeoul 06974Republic of Korea Department of Biological Sciences Sungkyunkwan UniversitySuwon 16419Republic of Korea

Mutualistic interactions between marine phototrophs and associated bacteria are an important strategy for their success-ful survival in the ocean,but little is known about their metabolic ***,bacterial communities in the algal sphere(AS)and bulk solution(BS)of nine marine red algal cultures were analyzed,and Roseibium and Phycisphaera were identified significantly more abundantly in AS than in *** metabolic features of Roseibium RMAR6-6(isolated and genome-sequenced),Phycisphaera MAG 12(obtained by metagenomic sequencing),and a marine red alga,Porphyridium purpureum CCMP1328(from GenBank),were analyzed ***6-6 has the genetic capability to fix nitrogen and produce B vitamins(B1,B2,B5,B6,B9,and B12),bacterioferritin,dimethylsulfoniopropionate(DMSP),and phenylacetate that may enhance algal growth,whereas MAG 12 may have a limited metabolic capability,not producing vitamins B9 and B12,DMSP,phenylacetate,and siderophores,but with the ability to produce bacitracin,possibly modulating algal *** CCMP1328 lacks the genetic capability to fix nitrogen and produce vitamin B12,DMSP,phenylacetate,and *** was shown that the nitrogen-fixing ability of RMAR6-6 promoted the growth of ***-pureum,and DMSP reduced the oxidative stress of *** metabolic interactions between strain RMAR6-6 and *** CCMP1328 were also investigated by the transcriptomic analyses of their monoculture and *** together,potential metabolic relationships between Roseibium and *** were *** study provides a bet-ter understanding of the metabolic relationships between marine algae and algae-associated bacteria for successful growth.

关键词： Metabolic relationship Marine red algae Symbiotic bacteria Roseibium Phycisphaera Porphyridium

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The symmetric space,strong isotropy irreducibility and equigeodesic properties

引用

Science China Mathematics 2024年第1期67卷 129-148页

作者： Ming Xu ju Tan School of Mathematical Sciences Capital Normal UniversityBeijing 100048China School of Microelectronics and Data Science Anhui University of TechnologyMa'anshan 243032China

A smooth curve on a homogeneous manifold G/H is called a Riemannian equigeodesic if it is a homogeneous geodesic for any G-invariant Riemannian *** homogeneous manifold G/H is called Riemannian equigeodesic,if for any x∈G/H and any nonzero y∈Tx(G/H),there exists a Riemannian equigeodesic c(t) with c(0)=x and ■(0)=*** two notions can be naturally transferred to the Finsler setting,which provides the definitions for Finsler equigeodesics and Finsler equigeodesic *** prove two classification theorems for Riemannian equigeodesic spaces and Finsler equigeodesic spaces,***,a homogeneous manifold G/H with a connected simply connected quasi compact G and a connected H is Riemannian equigeodesic if and only if it can be decomposed as a product of Euclidean factors and compact strongly isotropy irreducible ***,a homogeneous manifold G/H with a compact semisimple G is Finsler equigeodesic if and only if it can be locally decomposed as a product,in which each factor is Spin(7)/G2,G2/su (3) or a symmetric space of compact *** results imply that the symmetric space and the strongly isotropy irreducible space of compact type can be interpreted by equigeodesic *** an application,we classify the homogeneous manifold G/H with a compact semisimple G such that all the G-invariant Finsler metrics on G/H are *** suggests a new project in homogeneous Finsler geometry,i.e.,to systematically study the homogeneous manifold G/H on which all the G-invariant Finsler metrics satisfy a certain geometric property.

关键词： equigeodesic equigeodesic space flag manifold orbit type stratification symmetric space strongly isotropy irreducible space

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Semicrystalline Unfused Polymer Donors with Backbone Halogenation toward Cost-Effective Organic Solar Cells

引用

Chinese Journal of Chemistry 2024年第7期42卷 752-759页

作者： Yuxin Kong Shijie ju Hongmei Qin Min Hun Jee Simeng Xia Jiaqi Ren Chao Gao Jianyu Yuan Wenyan su Han Young Woo Yuxiang Li School of Materials Science and Engineering Xi'an University of Science and TechnologyXianShaanxi 710054China Department of Chemistry Korea UniversitySeoul 02841Republic of Korea Xi'an Key Laboratory of Liquid Crystal and Organic Photovoltaic Materials State Key Laboratory of Fluorine&Nitrogen ChemicalsXi'an Modern Chemistry Research InstituteXi'anShaanxi 710065China Jiangsu Key Laboratory for Carbon-Based Functional Materials&Devices Institute of Functional Nano&Soft Materials(FUNSOM)Soochow University199 Ren'ai RoadSuzhouJiangsu 215123China

Developing novel unfused building blocks with simple synthesis and low cost is essential to advance and enrich cost-effective poly-mer donors;however,it remains a challenge due to the lack of efficient molecular ***,a class of low-cost and fully unfused polymer donors with precisely regulated backbone planarity via halogenation was designed and synthesized,namely PDTBTBz-2H,PDTBTBz-2F,and *** polymer donors possess a four-step synthesis route with over 80%yield from cheap raw chemicals comparable to existing low-cost polymer donors,such as *** from the planar backbone via in-corporating the F…S non-covalent interactions,PDTBTBz-2F exhibits more robust J-type aggregation in solution and a long-ranged molecular stacking in film relative to PDTBTBz-2H and ***,the systematical study of PDTBTBz-based organic so-lar cells(OSCs)reveals the close relationship between optimized molecular self-assembly and charge separation/transport regarding backbone halogenation when paired with the non-fullerene acceptor(Y6-BO-4F).As a result,the photovoltaic devices based on semicrystalline PDTBTBz-2F achieved a promising power conversion efficiency(PCE)of 12.37%.Our work highlighted the influence of backbone halogenation on the molecular self-assembly properties and a potential unfused backbone motif for further developing cost-effective OSCs.

关键词： Low-cost Polymer donors Backbone halogenation Molecular self-assembly Organic solar cells

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Changes in the Non-targeted Metabolomic Profile of Three-year-old Toddlers with Elevated Exposure to Polycyclic Aromatic Hydrocarbons

引用

Biomedical and Environmental Sciences 2024年第5期37卷 479-493页

作者： LI Yang LIN Dan ZHANG Xiu Qin ju Guang Xiu su Ya ZHANG Qian DUAN Hai Ping YU Wei Sen WANG Bing Ling PANG Shu Tao Department of Epidemiology and Health Statistics School of Public HealthQingdao UniversityQingdao 266021ShandongChina Department of Environmental Health Qingdao Municipal Center for Disease Control and PreventionQingdao Institute of Preventive MedicineQingdao 266033ShandongChina Physicochemical Laboratory Qingdao Municipal Center for Disease Control and PreventionQingdao Institute of Preventive MedicineQingdao 266033ShandongChina Section of Child Health Care Huangdao Maternity and Child Health Care Hospital of QingdaoQingdao 266499ShandongChina Qingdao Blood Center Qingdao 266071ShandongChina

Objective To investigate changes in the urinary metabolite profiles of children exposed to polycyclic aromatic hydrocarbons(PAHs)during critical brain development and explore their potential link with the intestinal *** Liquid chromatography-tandem mass spectrometry was used to determine ten hydroxyl metabolites of PAHs(OH-PAHs)in 36-month-old ***,37 children were categorized into low-and high-exposure groups based on the sum of the ten ***-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry was used to identify non-targeted metabolites in the urine ***,fecal flora abundance was assessed by 16S rRNA gene sequencing using Illumina *** The concentrations of 21 metabolites were significantly higher in the high exposure group than in the low exposure group(variable importance for projection>1,Psure in young children affected metabolic homeostasis,particularly that of certain gut microbiota-derived *** investigation is needed to explore the potential influence of PAHs on the gut microbiota and their possible association with neurodevelopmental outcomes.

关键词： Child Gut microbiota Non-targeted metabolomics Polycyclic aromatic hydrocarbons Urinary metabolite profile

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Acupuncture ameliorates atopic dermatitis by modulating gut barrier function in a gut microbiota-dependent manner in mice

引用

Journal of Integrative Medicine 2024年第5期22卷 600-613页

作者： Mijung Yeom Sora Ahn Dae-Hyun Hahm sun-Young Jang Se Hoon Jang su-Yang Park Jae-Hwan Jang Jihan Park ju-Young Oh In-Seon Lee Kyuseok Kim Soon-Kyeong Kwon Hi-Joon Park Acupuncture and Meridian Science Research Center College of Korean MedicineKyung Hee UniversitySeoul 02447Republic of Korea Department of Physiology School of MedicineKyung Hee UniversitySeoul 02447Republic of Korea BioNanocomposite Research Center Kyung Hee UniversitySeoul 02447Republic of Korea Department of Science in Korean Medicine College of Korean MedicineGraduate SchoolKyung Hee UniversitySeoul 02447Republic of Korea College of Korean Medicine Kyung Hee UniversitySeoul 02447Republic of Korea Department of Ophthalmology Otorhinolaryngology and Dermatology of Korean MedicineCollege of Korean MedicineKyung Hee UniversitySeoul 02447Republic of Korea Division of Applied Life Science(BK21) Gyeongsang National UniversityJinju 52828Republic of Korea Department of Anatomy&Information Sciences College of Korean MedicineKyung Hee UniversitySeoul 02447Republic of Korea

Objective Atopic dermatitis(AD)is a chronic inflammatory skin disease that may be linked to changes in the gut *** has been proven to be effective in reducing AD symptoms without serious adverse events,but its underlying mechanism is not completely *** purpose of this study was to investigate whether the potential effect of acupuncture on AD is gut *** AD-like skin lesions were induced by applying MC903 topically to the cheek of the *** was done at the Gok-Ji(LI11)***-like symptoms were assessed by lesion scores,scratching behavior,and histopathological changes;intestinal barrier function was measured by fecal output,serum lipopolysaccharide levels,histopathological changes,and mRNA expression of markers involved in intestinal permeability and *** microbiota was profiled using 16S rRNA gene sequencing from fecal *** Acupuncture effectively improved chronic itch as well as the AD-like skin lesions with epidermal thickening,and also significantly altered gut microbiota structure as revealed byβ-diversity indices and analysis of *** beneficial effects were eliminated by antibiotic depletion of gut microbiota,but were reproduced in gut microbiota-depleted mice that received a fecal microbiota transplant from acupuncture-treated ***,AD mice had intestinal barrier dysfunction as indicated by increased intestinal permeability,atrophy of the mucosal structure(reduced villus height and crypt depth),decreased expression of tight junctions and mucus synthesis genes,and increased expression of inflammatory mediators in the *** attenuated these abnormalities,which was gut *** Acupuncture ameliorates AD-like phenotypes in a gut microbiota-dependent manner and some of these positive benefits are explained by modulation of the intestinal barrier,providing new perspective for non-pharmacological strategies for

关键词： Atopic dermatitis Acupuncture Gut microbiota Intestinal barrier function

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

LLM-105的分子间相互作用和热力学性质

引用

物理学报 2024年第4期73卷 235-244页

作者：范俊宇高楠王鹏举苏艳太原师范学院物理系晋中030619 台州学院材料科学与工程学院台州318000 之江实验室杭州311100 大连理工大学三束材料改性教育部重点实验室大连116024

应用第一性原理可以计算含能材料0 K下的结构和物理性质,但温度效应的缺失通常会导致计算数据与实验结果产生偏差.同时,与温度相关的热力学参数是含能材料在宏观和介观尺度下建模的关键输入.为此,本文以高能低感炸药1-氧-2,6-二氨基-3,5... 详细信息

应用第一性原理可以计算含能材料0 K下的结构和物理性质,但温度效应的缺失通常会导致计算数据与实验结果产生偏差.同时,与温度相关的热力学参数是含能材料在宏观和介观尺度下建模的关键输入.为此,本文以高能低感炸药1-氧-2,6-二氨基-3,5-二硝基吡嗪(LLM-105)为研究体系,基于准简谐近似,采用色散修正的密度泛函理论研究温度加载下LLM-105的分子间相互作用和热力学性质.晶格参数和热膨胀系数的演化表明LLM-105分子间相互作用具有强烈的各向异性,其中b轴方向(分子层间)的膨胀率远高于ac平面(分子层内).Hirshfeld表面及其指纹图分析进一步证实LLM-105的分子间相互作用主要取决于O···H构成的氢键.结合Mulliken布居数和结构分析,温度加载下氢键相互作用的变化可诱发硝基旋转,并使得C—NO_(2)键的强度明显减弱,为高温分解反应的触发键提供了理论依据.此外,本文计算了等容和等压条件下的热容、熵以及等温和绝热条件下的体模量等基础热力学参数.其中绝热条件下的体模量与实验值吻合,同时体模量随温度的演化反映了LLM-105在温度加载下的软化行为.上述理论研究可用于构建含能材料在介观和宏观尺度下的模型,也为测量原子分子水平下的热力学性质提供了重要的参考价值.

关键词： LLM-105 热力学性质分子间相互作用准简谐近似

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：