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Androgen deprivation therapy and side effects:are GnRH antagonists safer?

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Asian journal of Andrology 2021年第1期23卷 3-10页

作者： stephen j Freedland Per-Anders Abrahamsson Division of Urology Department of SurgeryCedars-Sinai Medical CenterLos AngelesCA 90048USA Section of Urology Durham VA Medical CenterDurhamNC 27705USA Department of Urology SkSne University HospitalLund UniversityMalmo 20502Sweden.

Androgen deprivation therapy(ADT)with gonadotropin-releasing hormone(GnRH)agonists and antagonists is the mainstay of advanced prostate cancer *** drug classes decrease levels of luteinizing hormone and follicle-stimulating hormones(FSH),thereby lowering testosterone to castrate *** is associated with adverse events(AEs),including cardiovascular(CV)disorders,bone fractures,metabolic dysfunction,and impaired cognitive *** literature review discusses these AEs,with a focus on CV and bone-related events.A hypothesis-generating meta-analysis of six clinical trials showed a potentially increased risk for CV disorders with GnRH agonists versus the GnRH antagonist *** no study has directly compared GnRH agonists versus antagonists with a primary CV outcome,one hypothesis for this observation is that GnRH agonists lead to initial surges in FSH that may negatively impact CV health,whereas antagonists do *** agonists are associated with metabolic and cognitive AEs and while data are lacking for GnRH antagonists,no differences in risk are *** common AEs with ADT include injection site reactions,which are much more common with degarelix than with GnRH agonists,which may reflect differing administration and injection *** studies are needed to further evaluate and compare the safety profiles of GnRH agonists and antagonists,especially in patients with pre-existing CV disease and other *** should carefully evaluate benefits and risks when prescribing ADT and ensure that side effects are well managed.

关键词： androgen antagonists metabolic syndrome prostate cancer safety

分子束外延生长ZnSe自组织量子点光、电行为研究

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物理学报 2002年第2期51卷 310-314页

作者：卢励吾王占国 C.L.Yang j.wang Z.H.Ma I.K.Sou Weikun Ge 中国科学院半导体研究所半导体材料科学开放实验室北京100083 香港科技大学物理系

分别应用光致发光、电容电压和深能级瞬态傅里叶谱技术详细研究ZnSe自组织量子点样品的光学和电学行为 .光致发光温度关系表明ZnSe量子点的光致发光热猝火过程机理 .两步猝火过程的理论较好模拟和解释了相关的实验数据 .电容电压测... 详细信息

分别应用光致发光、电容电压和深能级瞬态傅里叶谱技术详细研究ZnSe自组织量子点样品的光学和电学行为 .光致发光温度关系表明ZnSe量子点的光致发光热猝火过程机理 .两步猝火过程的理论较好模拟和解释了相关的实验数据 .电容电压测量表明样品表观载流子积累峰出现的深度 (样品表面下约 10 0nm处 )大约是ZnSe量子点层的位置 .深能级瞬态傅里叶谱获得的ZnSe量子点电子基态能级位置为ZnSe导带下的 0 11eV ,这与ZnSe量子点光致发光热猝火模型得到的结果一致 .

关键词： Ⅱ-Ⅵ半导体自组织量子点 ZnSe 分子束外延生长光学特性电学特性硒化锌

Radiological features of traumatic vertebral endplate fracture:an analysis of 194 cases with 263 vertebral fractures

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Chinese Medical journal 2020年第22期133卷 2696-2702页

作者： Xiao-Rong wang Fei-Rong Xu Qiu-Li Huang Yi Xiang j.wang Department of Radiology Ningbo First HospitalNingboZhejiang 315010China Department of Imaging and Interventional Radiology Faculty of MedicinePrince of Wales HospitalThe Chinese University of Hong KongHong KongChina Department of Radiology Ningbo Women and Children's HospitalNingboZhejiang 315012China

Background:The importance of identifying osteoporotic vertebral endplate or/and cortex fracture(ECF),which primarily includes endplate fracture(EPF)and vertebral anterior cortex buckling,has been ***,some old traumatic ECFs with healing process in the elderly may be mistaken as *** study analyzes the radiological features of traumatic ***:This was a retrospective analysis of 194 spine trauma patients with 263 vertebral fractures(mean age:42.11±9.82 years,118 males and 76 females).All patients had traumatic EPF identified by X-ray/CT/***:The involved vertebra was mostly L1(29.7%),followed by T12 and *** EPFs involved both superior and inferior endplates(12.6%),only 1.9%involved inferior endplate alone,with the majority involved superior *** each endplate was divided into five segments of equal lengths(from anterior to posterior:a1,a2,m,p2,p1),the most depressed point of superior EPFs was mostly at segment-a2(approximately 45%),followed by segment-a1(approximately 20%)or segment-m(approximately 20%),and very rarely at *** upper 1/3 of anterior vertebral wall was more likely to fracture,followed by middle 1/3 of anterior *** posterior vertebral wall fracture,68.5%broke the bony wall surrounding the basivertebral vain.58.6%,30.0%,and 11.4%of vertebral fractures had1/3 vertebral body height *** the extent of vertebral height loss increased,the chance of having both superior and inferior EPFs also increased;however,the chance of having inferior EPF alone did not ***:Traumatic EPF features are characterized,which may help the differentiation of traumatic and osteoporotic EPFs.

关键词： Spine Vertebral fracture Endplate Traumatic Vertebral cortex

An investigation on the best-fit models for sugarcane biomass estimation by linear mixedeffect modelling on unmanned aerial vehicle-based multispectral images:A case study of Australia

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Information Processing in Agriculture 2023年第3期10卷 361-376页

作者： Sharareh Akbarian Chengyuan Xu Weijin wang stephen Ginns Samsung Lim School of Civil and Environmental Engineering University of New South WalesSydney 2052Australia School of Health Medical and Applied SciencesCentral Queensland UniversityBundaberg 4670Australia Science&Technology Division Department of Environment and ScienceQueensland 4017Australia Queensland Department of Agriculture and Fisheries Brisbane 4000Australia

Due to the worldwide population growth and the increasing needs for sugar-based products,accurate estimation of sugarcane biomass is critical to the precise monitoring of sugarcane *** research aims to find the imperative predictors correspond to the random and fixed effects to improve the accuracy of wet and dry sugarcane biomass estimations by integrating ground data and multi-temporal images from Unmanned Aerial Vehicles(UAVs).The multispectral images and biomass measurements were obtained at different sugarcane growth stages from 12 plots with three nitrogen fertilizer *** spectral bands and different combinations of the plots,growth stages,and nitrogen fertilizer treatments were investigated to address the issue of selecting the correct fixed and random effects for the modelling.A model selection strategy was applied to obtain the optimum fixed effects and their proportional *** results showed that utilizing Green,Blue,and Near Infrared spectral bands on models rather than all bands improved model performance for wet and dry biomass ***,the combination of plots and growth stages outperformed all the candidates of random *** proposed model outperformed the Multiple Linear Regression(MLR),Generalized Linear Model(GLM),and Generalized Additive Model(GAM)for wet and dry sugarcane biomass,with coefficients of determination(R2)of 0.93 and 0.97,and Root Mean Square Error(RMSE)of 12.78 and 2.57 t/ha,*** study indicates that the proposed model can accurately estimate sugarcane biomasses without relying on nitrogen fertilizers or the saturation/senescence problem of Vegetation Indices(VIs)in mature growth stages.

关键词： Sugarcane biomass estimation Unmanned Aerial Vehicle(UAV) Random effects Nitrogen fertilizer treatment Model selection Vegetation Index(VI)

A low redox potential and long life organic anode material for sodium-ion batteries

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journal of Energy Chemistry 2025年第1期100卷 557-564页

作者： Zhi Li Yang Wei Kang Zhou Xin Huang Xing Zhou jie Xu Taoyi Kong junwei Lucas Bao Xiaoli Dong Yonggang wang Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Institute of New Energy Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) Fudan University Department of Chemistry Boston College School of Materials Science and Engineering Anhui University of Technology

Sodium-ion batteries （SIBs） with organic electrodes are an emerging research direction due to the sustainability of organic materials based on elements like C,H,O,and sodium ***,organic electrode materials for SIBs are mainly used as cathodes because of their relatively high redox potentials（>1 V）.Organic electrodes with low redox potential that can be used as anode are ***,a novel organic anode material （tetrasodium 1,4,5,8-naphthalenetetracarboxylate,Na4TDC） has been developed with low redox potential （<0.7 V） and excellent cyclic *** three-sodium storage mechanism was demonstrated with various in-situ/ex-situ spectroscopy and theoretical calculations,showing a high capacity of 208 mAh/g and an average decay rate of merely 0.022%per ***,the Na4TDC-hard carbon composite can further acquire improved capacity and cycling stability for 1200 cycles even with a high mass loading of up to 20 mg *** pairing with a thick Na3V2（PO4）3cathode (20.6 mg cm-2),the as-fabricated full cell exhibited high operating voltage （2.8 V）,excellent rate performance and cycling stability with a high capacity retention of 88.7% after 200 cycles,well highlighting the Na4TDC anode material for SIBs.

关键词： Organic anode material Low redox potential Composite anode Sodium-ion batteries

THE EROSIVE PROCESS IN ABRASIVE WATERjET CUTTING OF POLYMER MATRIX COMPOSITES

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Acta Metallurgica Sinica(English Letters) 1999年第5期12卷 886-890页

作者： j.wang School of Mechanical, Manufacturing and Medical Engineering, Queensland University of Technology, GPO Box 2434, Brisbane, Qld. 4001, Australia

A study is carried out which analyzes the machinability of polymer matrix composites under an abrasive waterjet (AWj) and the associated erosive process or mechanism. It shows that AWj cutting can produce good quality kerf at high production rate if the cutting parameters are properly selected. A scanning electron microscopy (SEM) analysis of the cut surfaces reveals that the erosive process for the matrix material (resin) involves shearing and ploughing as well as intergranular cracking, while shearing is a dominant process for cutting the fibres in the upper cutting region but the fibers are mostly pulled out in the lower region.

关键词： abrasive waterjet composite materials erosive process machinability

体育管理研究与理论构建、检验中的核心问题——体育管理学研究设计、测量和分析系列

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上海体育学院学报 2016年第1期40卷 4-11页

作者： james j.Zhang james W.Du jerry j.wang 张轶美国佐治亚大学国际体育管理研究中心佐治亚州雅典30602 美国天普大学福克斯商学院宾夕法尼亚州费城19122 上海大学体育学院上海200444

为引导青年学者开展高水平体育管理研究,本系列论文(由6篇文章组成,未来2年内陆续向读者呈现)旨在阐明中高级科学研究理念、研究流程、设计应用、测量方法、数据分析,及它们的集成性和在体育管理理论检验与发展中的功能。首篇将综述体... 详细信息

为引导青年学者开展高水平体育管理研究,本系列论文(由6篇文章组成,未来2年内陆续向读者呈现)旨在阐明中高级科学研究理念、研究流程、设计应用、测量方法、数据分析,及它们的集成性和在体育管理理论检验与发展中的功能。首篇将综述体育产业发展的背景信息,指出日益增长的科学研究需求和激烈的学术竞争环境,并讨论在体育管理研究与理论构建、检验中的核心问题。最后,揭示系列拣选内容所遵循的基本逻辑。

关键词：体育管理科学研究理论框架测量评价市场分析设计

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互依变量分析在体育管理研究中的应用

上海体育学院学报 2017年第4期41卷 41-48,56页

作者： jerry j.wang Kevin K.Byon james j.Zhang 安俊英美国西佐治亚大学体育管理健康与教育系佐治亚州卡罗顿30116 美国印第安纳大学运动学系印第安纳州伯明顿47405 美国佐治亚大学国际体育管理研究中心佐治亚州雅典30602 上海体育学院经济管理学院上海200438

介绍互依变量分析的统计程序与技术及其在体育管理研究中的应用,包括聚类分析、探索性因子分析、验证性因子分析,并结合实证研究的设计逐步进行说明,为体育管理研究者提供"即学即用"的研究方法指南。

关键词：体育管理类别分析因子效度建构效度互依变量分析聚类分析探索性因子分析验证性因子分析

Adsorption and Photocatalytic Decomposition of Methylene Blue on Monodispersed Nanoparticles M2O5-nH2O Catalyst

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Adsorption and Photocatalytic Decomposition of Methylene Blu...