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RIP140, a Janus metabolic switch involved in defense functions

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Cellular & Molecular Immunology 2013年第1期10卷 7-9页

作者： Hun Taeg chung School of Biological Sciences University of Ulsan Meta-Inflammation Basic Research Laboratory Ulsan KoreaCorrespondence: Dr HT Chung School of BiologicalSciences University of Ulsan Meta-lnflammation BasicResearch Laboratory Ulsan Korea.

Since its discovery almost 15 years ago, the receptor-interacting protein RIP140has been determined to be a corepressor of various transcription factors and nuclear receptors. Mice lacking the RIP140 gene are lean, exhibit resistance to high-fat diet- induced obesity and have increased glucose tolerance and insulin sensitivity. In 2008, RIP140 was determined to be a coactivator of nuclear factor-~cB, a master transcriptional regulator of inflammation in immune cells, including macrophages. This year, it was reported that RIP 140 degradation is involved in the resolution of inflammation and in endotoxin tolerance. The general picture that had emerged indicates that RIP140 is a ]anus metabolic switch that convergently regulates metabolic pathways involved in defense func- tions through its pleotropic interactions with transcription factors.

关键词： RIP140 Janus metabolic switch defense functions

Experimental Investigation of Aerodynamic Performance due to Blade Tip Clearance in a Gas Turbine Rotor Cascade

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Journal of Thermal Science 2022年第1期31卷 173-178页

作者： chung Jinmoo BAEK Seungchan HWANG Wontae Department of Mechanical Engineering Seoul National UniversitySeoul 08826Republic of Korea Institute of Advanced Machines and Design Seoul National UniversitySeoul 08826Republic of Korea Institute of Engineering Research Seoul National UniversitySeoul 08826Republic of Korea

This study examines how the complex flow structure within a gas turbine rotor affects aerodynamic loss. An unshrouded linear turbine cascade was built, and velocity and pressure fields were measured using a 5-hole probe. In order to elucidate the effect of tip clearance, the overall aerodynamic loss was evaluated by varying the tip clearance and examining the total pressure field for each case. The tip clearance was varied from 0% to 4.2% of blade span and the chord length based Reynolds number was fixed at 2×10^(5). For the case without tip clearance, a wake downstream of the blade trailing edge is observed, along with hub and tip passage vortices. These flow structures result in profile loss at the center of the blade span, and passage vortex related losses towards the hub and tip. As the tip clearance increases, a tip leakage vortex is formed, and it becomes stronger and eventually alters the tip passage vortex. Because of the interference of the secondary tip leakage flow with the main flow, the streamwise velocity decreases while the total pressure loss increases significantly by tenfold in the last 30% blade span region towards the tip for the 4.2% tip clearance case. It was additionally observed that the overall aerodynamic loss increases linearly with tip clearance.

关键词： gas turbine turbine cascade aerodynamic loss tip clearance tip leakage

Essentials of thoracic outlet syndrome:A narrative review

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World Journal of Clinical Cases 2021年第21期9卷 5804-5811页

作者： Min cheol Chang Du Hwan Kim Department of Rehabilitation Medicine College of MedicineYeungnam UniversityDaegu 42415South Korea Department of Physical Medicine and Rehabilitation College of MedicineChung-Ang UniversitySeoul 06973South Korea

Thoracic outlet syndrome(TOS)is a group of diverse disorders involving compression of the nerves and/or blood vessels in the thoracic outlet *** results in pain,numbness,paresthesia,and motor weakness in the affected upper *** reviewed the pathophysiology,clinical evaluation,differential diagnoses,and treatment of *** is usually classified into three types,neurogenic,venous,and arterial,according to the primarily affected *** true neurogenic and disputed TOS are considered neurogenic *** identifying the causative lesions is complex,detailed history taking and thorough clinical investigation are *** and imaging studies are helpful for excluding other possible disorders and confirming the diagnosis of true neurogenic *** existence of a disputed TOS remains *** physicians tend to be skeptical about the existence of disputed TOS,but thoracic surgeons argue that disputed TOS is *** who encounter patients with TOS need to understand its key features to avoid misdiagnosis and provide appropriate treatment.

关键词： Brachial plexus Diagnosis Review Thoracic outlet syndrome Treatment Neuromuscular lesions

Lithium Salt of NH_2-substituted Graphene Nanoribbon with Twofold Donor-acceptor Framework: Large Nonlinear Optical Property

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Chemical Research in Chinese Universities 2011年第3期27卷 512-515页

作者： SUN Chia-chung State Key Laboratory of Theoretical and Computational Chemistry Institute of Theoretical Chemistry Jilin University

Based on graphene, a new class of second-order nonlinear optical（NLO） material, the lithium salt of NH2-substituted graphene nanoribbon with the twofold donor（D）/acceptor（A） mode, was reported. Eight stable 2Li-2NH2-GNR lithium salts, especially cis lithium salts, display considerably large β0 values. The combination of NH2-substituting and cis Li-doping makes β0 greatly increased from 0（GNR） to 1.2×105―2.9×105 a.u.（cis-2Li- 2NH2-GNRs）. Our largest β0 value（2.9×105 a.u.） for cis-2Li-1,3-2NH2-AGNR is comparable to the record value of 1.7×105 a.u. for a long donor-acceptor polyene.

关键词： First hyperpolarizability Nonlinear optical material Twofold donor-acceptor mode

Discovery of Middle Jurassic palaeontinids from Inner Mongolia, China (Homoptera: Palaeontinidae)

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Progress in Natural Science:Materials International 2007年第1期17卷 112-116页

作者： SHIH chung Kun China College of Life Science Capital Normal University Beijing 100037

A new genus and three new species of fossil Palaeontinidae, Papilioncossus conchatus sp. nov., P. giganteus sp. nov. and P. pteroideus sp. nov., are described. All of them were collected from Middle Jurassic Jiulongshan Formation in Inner Mongolia, China. Based on distal part of forewing broader and longer than basal and Sc usually with branches, the new taxa are attributed to Palaeontinidae of Homoptera and compared with genus Pseudocossus. A key to species of Papilioncossus gen. nov. is provided. All type specimens are deposited in the Capital Normal University.

关键词： Palaeontinidae fossil Middle Jurassic new genus new species Inner Mongolia.

SHP gains citizenship of the AMPK kingdom

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Cellular & Molecular Immunology 2011年第6期8卷 450-452页

作者： Hun-Taeg chung School of Biological Sciences University of UlsanMetaInflammation Basic Research LaboratoryUlsanKorea

Various cytokines and chemokines are produced as a result of signaling through innate immune *** signaling is initiated by host–pathogen interactions in which the host’s germline-encoded pattern recognition receptors,including Toll-like receptors(TLRs),recognize conserved microbial structures termed pathogen-associated molecular *** are broadly distributed in immune cells and are responsible for eliciting innate responses and enhancing adaptive immunity to *** 12 members of the TLR family in mammals are characterized by an extracelluar leucine-rich repeat domain and an intracellular Toll/IL-1 receptor domain.

关键词： immunity cytokines initiated

Seasonal dynamics of airborne biomolecules influence the size distribution of Arctic aerosols

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Environmental Science and Ecotechnology 2024年第6期22卷 245-255页

作者： Eunho Jang Ki-Tae Park Young Jun Yoon Kyoung-soon Jang Min Sung Kim Kitae Kim Hyun Young chung Mauro Mazzola David Cappelletti Bang Yong Lee Korea Polar Research Institute(KOPRI) Incheon21990Republic of Korea University of Science and Technology(UST) Daejeon34113Republic of Korea Department of Environmental Sciences and Biotechnology Hallym UniversityChuncheonGangwon-do24252Republic of Korea Korea Basic Science Institute(KBSI) Cheongju28119Republic of Korea National Research Council of Italy Institute of Polar Sciences(CNR-ISP)Via Gobetti 101Bologna40129Italy Department of Chemistry Biology and BiotechnologyUniversity of PerugiaVia Elce di Sotto 8Perugia06123Italy

Organic matter is crucial in aerosol-climate interactions,yet the physicochemical properties and origins of organic aerosols remain poorly *** we show the seasonal characteristics of submicron organic aerosols in Arctic Svalbard during spring and summer,emphasizing their connection to transport patterns and particle size ***-derived organic matter(MOM)and terrestrial-derived organic matter(TOM)accounted for over 90%of the total organic mass in Arctic aerosols during these seasons,comprising carbohydrate/protein-like and lignin/tannin-like compounds,*** spring,aerosols showed high TOM and low MOM intensities due to biomass-burning influx in the central *** contrast,summer exhibited elevated MOM intensity,attributed to the shift in predominant atmospheric transport from the central Arctic to the biologically active Greenland *** and TOM were associated with Aitken mode particles(100 nm diameter),*** association is linked to the molecular size of biomolecules,impacting the number concentrations of corresponding aerosol *** findings highlight the importance of considering seasonal atmospheric transport patterns and organic source-dependent particle size distributions in assessing aerosol properties in the changing Arctic.

关键词： Organic aerosol FT-ICR MS Particle size distribution Atmospheric transport pattern Biomolecule

Distributed Intelligent Microgrid Control Using Multi-Agent Systems

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Engineering（科研） 2013年第1期5卷 1-6页

作者： Il-Yop chung cheol-Hee Yoo Sang-Jin Oh School of Electrical Engineering Kookmin UniversitySeoul Republic of Korea

In the future, the individual entities of microgrids such as distributed generators and smart loads may need to determine their power generation or consumption in more economic ways. Intelligent agents can help the decision-making procedure of the entities by intelligent algorithms and state-of-the-art communication with central controller and other local agents. This paper presents the development of atable-top microgrid control system using multi-agent systems and also the demonstration of demand response programs during power shortage. In our table-top system, agents are implemented using microcontrollers and Zigbee wireless communication technology is applied for efficient data communication in the multi-agent system. The power system models of distributed generators and loads are implemented in the real-time simulator using Opal-RT system. The whole test system that includes real-time system simulation and agent hardware is implemented in the hardware-in-the-loop simulation framework. The performance of the developed system is tested for emergency demand response cases.

关键词： Microgrid Multi-agent System Energy Management System Hardware-in-the-Loop Simulation

Nondriven Polymer Translocation Through a Nanopore: Scaling for Translocation Time with Chain Length

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Chemical Research in Chinese Universities 2011年第6期27卷 1023-1026页

作者： SUN Chia-chung State Key Laboratory of Theoretical and Computational Chemistry Institute of Theoretical Chemistry Jilin University

We investigated the dynamics of the passage for a polymer chain through a nanopore in the absence of any external driving force with Weeks-Chandler-Andersen potential in two-dimensional simulations, in particular, focused our attention on the scaling law of the mean translocation time. We found that the effect of hydrodynamic interactions is the major factor in determining the scaling exponents with increasing pore size. The scaling close to N1＋2v was observed when the hydrodynamic interactions were screened in the cases of small pore sizes, while the scaling close to N3v was obtained when the hydrodynamic interactions were present in the cases of large pore sizes.

关键词： Translocation Nondriven Hydrodynamic interaction