SHP gains citizenship of the AMPK kingdom
作者机构:School of Biological SciencesUniversity of UlsanMetaInflammation Basic Research LaboratoryUlsanKorea
出 版 物:《Cellular & Molecular Immunology》 (中国免疫学杂志(英文版))
年 卷 期:2011年第8卷第6期
页 面:450-452页
核心收录:
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题:immunity cytokines initiated
摘 要:Various cytokines and chemokines are produced as a result of signaling through innate immune *** signaling is initiated by host–pathogen interactions in which the host’s germline-encoded pattern recognition receptors,including Toll-like receptors(TLRs),recognize conserved microbial structures termed pathogen-associated molecular *** are broadly distributed in immune cells and are responsible for eliciting innate responses and enhancing adaptive immunity to *** 12 members of the TLR family in mammals are characterized by an extracelluar leucine-rich repeat domain and an intracellular Toll/IL-1 receptor domain.