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Soft,body conformable electronics for thermoregulation enabled by kirigami

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Bio-Design and Manufacturing 2024年第4期7卷 453-462页

作者： Lung Chow Guangyao Zhao Pengcheng Wu Xingcan Huang Jiyu Li Jian Li Wanying Wang Guihuan guo Zhiyuan Li Jiachen Wang jingkun Zhou Yawen Yang Yuyu Gao Binbin Zhang Qiang Zhang Dengfeng Li Ya Huang Kuanming Yao Jian Lu Xinge Yu Department of Biomedical Engineering City University of Hong KongHong Kong 999077China Hong Kong Centre for Cerebro-Cardiovascular Health Engineering Hong Kong 999077China Department of Biomedical Sciences City University of Hong KongHong Kong 999077China Department of Mechanical Engineering City University of Hong KongHong Kong 999077China

The application of thermoelectric devices(TEDs)for personalized thermoregulation is attractive for saving energy while balancing the quality of *** that directly attach to human skin remarkably minimized the energy wasted for cooling the entire ***,facing the extreme dynamic geometry change and strain of human skin,conventional TEDs cannot align with the contour of our bodies for the best thermoregulation ***,we designed a kirigami-based wearable TED with excellent water vapor permeability,flexibility,and *** analysis and experimental results reveal that our product can withstand various types of large mechanical deformation without circuit *** stated outcome and proposed facile approach not only reinforce the development of wearable TEDs but also offer an innovative opportunity for different electronics that require high conformability.

关键词： Thermoregulation Thermoelectric Kirigami Body conformable Wearable

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T/R双模微波功率模块技术及其应用

强激光与粒子束 2024年第1期36卷 12-17页

作者：李建兵邱立王斌郭静坤董雪雨战略支援部队信息工程大学信息系统工程学院郑州450001 中国电子科技集团公司第十二研究所北京100015 中国电子科技集团公司第二十九研究所成都610036

微波功率模块(MPM)是真空电子器件和固态电子器件组合而成的一种新型微波功率器件,具有频率高、频带宽、功率大、体积重量小等特点,它使常规行波管的应用变得更加便利和广泛。现代战争向雷达、电子战综合一体化方向发展,这就要求功放既... 详细信息

微波功率模块(MPM)是真空电子器件和固态电子器件组合而成的一种新型微波功率器件,具有频率高、频带宽、功率大、体积重量小等特点,它使常规行波管的应用变得更加便利和广泛。现代战争向雷达、电子战综合一体化方向发展,这就要求功放既能工作在高峰值功率、低占空比的高模工作方式,也能工作在低峰值功率、准连续波的低模工作方式,针对这一需求,结合电子系统收发共孔径的要求,提出了T/R双模MPM技术。T/R双模MPM技术的核心是T/R双模行波管,基于三端口双向T/R行波管,通过在慢波系统的衰减器附近设置一个耦合口,实现行波管的信号反向接收功能;通过T/R双模行波管设计、双模放大均衡组件、双调制栅极电源等技术实现MPM的双模双向功能。T/R双模MPM应用前景广阔,特别是在基于无人机平台的作战应用中的具有明显优势。

关键词：微波功率模块 T/R行波管收发共孔径功放均衡器

Carbohydrate-derived porous carbon materials:An ideal platform for green organic synthesis

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Chinese Chemical Letters 2022年第1期33卷 186-196页

作者： Yamei Lin Jie Yu Xing Zhang jingkun Fang guo-Ping Lu He Huang School of Food Science and Pharmaceutical Engineering Nanjing Normal UniversityNanjing 210023China School of Pharmaceutical Sciences Nanjing Tech UniversityNanjing 210009China School of Chemical Engineering Nanjing University of Science and TechnologyNanjing 210094China

Porous carbon materials have attracted much attention in the field of organic synthesis in recent years,due to their tunable properties,excellent catalytic activity and ***-based carbohydrates emerge as an ideal precursor for the generation of these materials owing to their renewability,low cost,non-toxicity and high content of functional ***,carbon materials prepared from carbohydrates is of considerable importance for the sustainable development of organic *** present review not only summarizes recent examples of carbohydrate-derived porous carbon material-catalyzed organic reactions including the oxidation,hydrogenation,cross-coupling,esterification and condensation reactions,but also introduces the preparation and functionalization strategies of these ***,the challenges and opportunities of organic synthesis over these sustainable materials have also been *** review will stimulate further research on exploring novel carbohydrate-derived porous carbon materials and new sustainable organic synthetic processes over these materials.

关键词： Carbohydrates Carbon materials Green chemistry Catalysis Organic synthesis

Trapping and Driving Individual Charged Micro-particles in Fluid with an Electrostatic Device

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Nano-Micro Letters 2016年第3期8卷 270-281页

作者： Jingjing Xu Zijing Lei jingkun guo Jie Huang Wei Wang Uta Reibetanz Shengyong Xu Key Laboratory for the Physics & Chemistry of Nanodevices and Department of Electronics Peking University Institute of Microelectronics Peking University Medical Faculty Institute for Medical Physics and Biophysics University of Leipzig

A variety of micro-tweezers techniques, such as optical tweezers, magnetic tweezers, and dielectrophoresis technique, have been applied intensively in precise characterization of micro/nanoparticles and bio-molecules. They have contributed remarkably in better understanding of working mechanisms of individual sub-cell organelles, proteins, and DNA. In this paper, we present a controllable electrostatic device embedded in a microchannel, which is capable of driving,trapping, and releasing charged micro-particles suspended in microfluid, demonstrating the basic concepts of electrostatic tweezers. Such a device is scalable to smaller size and offers an alternative to currently used micro-tweezers for application in sorting, selecting, manipulating, and analyzing individual micro/nanoparticles. Furthermore, the system offers the potential in being combined with dielectrophoresis and other techniques to create hybrid micro-manipulation systems.

关键词： Electrostatic tweezers Charged particles Coulomb potential well Manipulation Trap

扇形束CT引导头颈部肿瘤放疗的智能摆位与人眼摆位精度比较

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中国眼耳鼻喉科杂志 2024年第5期24卷 418-422页

作者：朱丽婷刘守鸿郭嘉俊王孝深复旦大学附属眼耳鼻喉科医院放疗科上海200031

目的比较扇形束CT(FBCT)引导校正下机器参与的一键智能摆位与传统人眼摆位精度的差异,并评估一键智能摆位在头颈部肿瘤放射治疗(简称放疗)各阶段的应用效果。方法针对在联影uRT-linac506c加速器上接受放疗的头颈部肿瘤患者,常规采用扇形... 详细信息

目的比较扇形束CT(FBCT)引导校正下机器参与的一键智能摆位与传统人眼摆位精度的差异,并评估一键智能摆位在头颈部肿瘤放射治疗(简称放疗)各阶段的应用效果。方法针对在联影uRT-linac506c加速器上接受放疗的头颈部肿瘤患者,常规采用扇形束CT引导的放疗(FBCT-RT),频率如下:前3次均FBCT-RT,之后每周1次FBCT-RT。分析患者三维方向的摆位误差。试验组于第2次FBCT-RT采用经FBCT校准后的一键智能摆位功能不进行人眼校准。对照组于第3次FBCT-RT采用人眼摆位。利用自身配对t检验比较2组间摆位时间和摆位误差。利用方差分析比较应用一键智能摆位功能下患者放疗第1~6周的每周摆位误差。2022年9月—2022年11月共有35例头颈部肿瘤患者进入研究。结果2组间垂直方向(VRT)、头脚方向(LNG)和左右方向(LAT)摆位误差总体均数的差异均有统计学意义(P0.05),恶性肿瘤后3周VRT则会出现个体化差异(P<0.05),但眼眶良性肿瘤的摆位在三维方向均维持稳定。结论基于FBCT引导下应用一键智能摆位后能减小头颈部肿瘤患者放疗前期摆位误差,节省摆位时间,对眼眶良性肿瘤应用效果最好。

关键词：头颈肿瘤智能摆位摆位误差扇形束CT引导放疗

Integrated optical-readout of a high-Q mechanical out-of-plane mode

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Light(Science & Applications) 2022年第10期11卷 2485-2491页

作者： jingkun guo Simon Groblacher Kavli Institute of Nanoscience Department of Quantum NanoscienceDelft University of Technology2628CJ DelftThe Netherlands

The rapid development of high-QM macroscopic mechanical resonators has enabled great advances in *** improvements could allow for quantum-limited or quantum-enhanced applications at ambient *** of the remaining challenges include the integration of high-QM structures on a chip,while simultaneously achieving large coupling strengths through an optical ***,we present a versatile fabrication method,which allows us to build fully integrated optomechanical *** place a photonic crystal cavity directly above a mechanical resonator with high-QM fundamental out-of-plane mode,separated by a small *** highly confined optical field has a large overlap with the mechanical mode,enabling strong optomechanical interaction ***,we implement a novel photonic crystal design,which allows for a very large cavity photon number,a highly important feature for optomechanical experiments and sensor *** versatile approach is not limited to our particular design but allows for integrating an out-of-plane optical read-out into almost any device ***,it can be scaled to large arrays and paves the way to realizing quantum experiments and applications with mechanical resonators based on high-QM out-of-plane modes alike.

关键词： optical resonator mode

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全三七片单次和重复给药毒性评价研究

辽宁中医药大学学报 2024年第1期26卷 15-30页

作者：谭莹廖伟廖文平李勇那敏郭湘楠杨露朱兆云王京昆云南省药物研究所云南昆明650111 云南省中药和民族药新药创制企业重点实验室云南昆明650111

目的在GLP条件下开展单次给药和重复给药毒性实验,观察全三七片的毒性作用和可逆性,推测毒性靶器官或靶组织,预测临床试验的安全剂量范围,为全三七片的安全性提供试验依据。方法采用SD大鼠为实验系统,通过观察一般临床体征,称量体质量... 详细信息

目的在GLP条件下开展单次给药和重复给药毒性实验,观察全三七片的毒性作用和可逆性,推测毒性靶器官或靶组织,预测临床试验的安全剂量范围,为全三七片的安全性提供试验依据。方法采用SD大鼠为实验系统,通过观察一般临床体征,称量体质量,评价摄食、饮量,检测血液学、血凝、血清生化学指标和生物标志物,称量脏器重量,计算脏器系数及对主要脏器组织进行病理学检查等方法,评价全三七片24 h内大剂量给药和连续13周持续给药对动物可能产生的毒性及其严重程度。结果 (1)全三七片24 h内2次灌胃的最大给药量为20.0 g·kg^(-1),给药后动物体质量正常增长,观察期内未见动物死亡和出现异常体征。(2)分别以1.5、2.6、6.8 g·kg^(-1)(简称:低、中、高剂量组)重复灌胃给予全三七片13周,可使SD大鼠出现稀便和/或软便及周平均摄食量和饮水量增加,中、高剂量组大鼠体质量增长略缓慢,高剂量组雌鼠血小板膜蛋白-140(GMP140)和雄鼠的红细胞(RBC)、网织红细胞(Retic)计数及百分比、甘油三酯(TG)轻微降低,高剂量组雌鼠肝系数(脏体比)和中、高剂量组雄鼠肝、肾系数(脏体比)增大,上述指标停药后均能恢复正常或呈恢复趋势。结论 (1)全三七片24 h内大剂量给药(相当于临床最大拟用剂量的665倍)具有较高的安全性。(2)全三七片重复给药13周的无不良反应剂量(NOAEL)为1.5 g·kg^(-1)(相当于临床最大拟用剂量的50倍),提示受试物具有较宽的安全剂量范围,但在临床使用过程中应密切关注胃肠系统功能并避免与有类似不良反应的药物合用。

关键词：全三七片 SD大鼠片单次给药毒性重复给药毒性

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纳米SiC及Si_3N_4/SiC的高温等静压研究

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无机材料学报 1997年第2期12卷 191-194页

作者：董绍明江东亮谭寿洪郭景坤中国科学院上海硅酸盐研究所上海200050

采用高温等静压（HIP）工艺，制备了纳米结构的单相SiC及Si3N4／SiC复相陶瓷，并通过X射线衍射分析、透射及高分辨电镜对其相组成及结构进行了表征．实验表明，在温度1850℃、压力200MPa条件下保温lh，可获得晶粒尺寸＜100nm、结构均匀... 详细信息

采用高温等静压（HIP）工艺，制备了纳米结构的单相SiC及Si3N4／SiC复相陶瓷，并通过X射线衍射分析、透射及高分辨电镜对其相组成及结构进行了表征．实验表明，在温度1850℃、压力200MPa条件下保温lh，可获得晶粒尺寸＜100nm、结构均匀、致密的单相SiC纳米结构陶瓷．对于St3N4／SiC复相体系，初始粉末的结晶形态对烧结体的结构有很大的影响.将初始粉末进行预处理后：在温度1750℃、压力150MPa条件下保温1h，可获得晶粒尺寸在50nm左右、结构致密、均匀的复相Si3N4／SiC纳米陶瓷材料．

关键词：纳米陶瓷高温等静压陶瓷压制成型碳化硅陶瓷

Solid-state-reaction fabrication and properties of a high-doping Nd:YAG transparent laser ceramic

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Frontiers of Chemical Science and Engineering 2008年第3期2卷 248-252页

作者： Jiang LI Yusong WU Yubai PAN Wenbin LIU Liqiong AN Shiwei WANG jingkun guo Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 200050China Graduate School of the Chinese Academy of Sciences Beijing 10039China

High-quality neodymium-doped yttrium aluminum garnet(Nd:YAG)transparent ceramic(4.0 mole percent)was fabricated by a solid-state reaction method and vacuum *** microstructure,optical transmittance,spectral properties and laser performance were *** average grain size of the sample is about 10 *** transmittance of a 2.8-mm thick sample reaches 79.5%at the laser wavelength of 1064 *** highest absorption peak is centered at 807 nm and the absorption coefficient is 13.9 cm^(-1).The absorption coefficient at the laser wavelength is 0.2 cm^(-1).The main emission peak is at 1064 nm and the fluorescence lifetime is 102 ms.A laser diode(808 nm)whose maximum output is about 1000 mW was used as a pump source and an endpumped laser experiment was *** 1064 nm-CW-laser output was obtained and the threshold is 733 *** 998 mW of maximum absorbed pump power,a laser output of 17 mW is obtained with a slope efficiency of 6.1%.

关键词： transparent laser ceramic optical properties microstructure high-doping concentration solid state reaction