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控制呼吸持续性监护仪临床应用的可行性和有效性

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吉林大学学报（医学版） 2024年第4期50卷 1123-1129页

作者：封俊杰路畅程圣权张霄孙旭芳吉林大学第二医院麻醉科吉林长春130022

目的:观察利用人工气道内温度节律性变化原理设计的控制呼吸持续性监护仪在不同人群和不同人工气道内的应用,探讨其监测控制呼吸持续性的可行性和有效性,为临床呼吸监测提供新方法。方法:选择择期行全身麻醉术的成人患者60例,1~3岁幼儿... 详细信息

目的:观察利用人工气道内温度节律性变化原理设计的控制呼吸持续性监护仪在不同人群和不同人工气道内的应用,探讨其监测控制呼吸持续性的可行性和有效性,为临床呼吸监测提供新方法。方法:选择择期行全身麻醉术的成人患者60例,1~3岁幼儿患者30例,美国麻醉师协会(ASA)分级Ⅰ-Ⅱ级;60例成人患者随机分为成人气管插管组(ATI组)和成人喉罩组(ALM组),每组30例,1~3岁幼儿患者30例设为幼儿气管插管组(CTI组)。全麻诱导后,CTI组和ATI组患者行气管插管,ALM组患者置入喉罩,连接麻醉机行机械通气,连接控制呼吸持续性监护仪,观察监护仪是否能探测出各组患者呼吸频率(RR),比较各组监护仪探测的RR和麻醉机设定频率;3组患者均于手术开始前模拟呼吸回路断开、麻醉机手控未转换为机控和呼吸回路缓慢漏气3种临床常见控制呼吸持续性改变场景,比较各组间监护仪发出报警方式和报警时间。结果:3组患者应用控制呼吸持续性监护仪均能检测出RR,各组内患者RR和麻醉机设定频率比较差异无统计学意义(P>0.05)。在模拟3种常见呼吸持续性改变的场景中,3组患者呼吸持续性监护仪均发出内容为“注意,呼吸停止”的人工语音报警信号,报警信号均被注意到,ATI组和ALM组控制呼吸持续性监护仪开始报警时间比较差异无统计学意义(P>0.05)。与回路缓慢漏气比较,同一组患者呼吸回路断开和手控未转换为机控场景时开始报警时间缩短(P<0.05)。结论:在不同人群和不同人工气道内利用探测人工气道内温度节律性升降变化原理设计的控制呼吸持续性监护仪临床应用具有可行性及有效性,可为术中呼吸持续性监测和保障呼吸安全提供新方法。

关键词：全身麻醉呼吸频率控制呼吸持续性监护仪呼吸气流温度

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他汀类药物联合多奈哌齐治疗NAFLD合并AD的疗效及对LCN2的影响

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黑龙江医药 2024年第1期37卷 1-3页

作者：何盛泉黄竹锋陈恺朱伟谦厦门弘爱医院神经内科福建厦门361000 漳州市第二医院内科综合病区福建漳州363199 漳州市第二医院消化内科福建漳州363199

目的:探讨他汀类药物联合多奈哌齐治疗NAFLD合并AD的疗效及对LCN2的影响。方法:选择本院2021年1月—2023年6月收治的66例NAFLD合并AD患者为研究对象,按电脑随机法分组,分为观察组(33例)和对照组(33例);对照组给予多奈哌齐治疗,观察组在... 详细信息

目的:探讨他汀类药物联合多奈哌齐治疗NAFLD合并AD的疗效及对LCN2的影响。方法:选择本院2021年1月—2023年6月收治的66例NAFLD合并AD患者为研究对象,按电脑随机法分组,分为观察组(33例)和对照组(33例);对照组给予多奈哌齐治疗,观察组在对照组基础上加用他汀类药物,比较两组治疗效果。结果:治疗后,观察组患者的氧化应激指标(MDA、SOD)对比具有显著差异(P<0.05),且观察组患者的SOD水平更高,MDA水平更低(P<0.05);治疗后,观察组ADL和MMSE评分高于对照组(P<0.05);治疗后,两组患者的LCN2水平明显降低,且观察组患者的LCN2指标低于对照组(P<0.05);治疗后,两组患者的不良反应发生率(6.06%VS18.18%)对比差异不大(t=2.276,P=0.131)。结论:在他汀类药物联合多奈哌齐治疗NAFLD合并AD的疗效十分显著,可加以应用和推广。

关键词：他汀类药物多奈哌齐 NAFLD合并AD 疗效 LCN2

Low.rank matrix recovery w.th total generalized variation for defending adversarial examples

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Frontiers of Information Technology & Electronic Engineering 2024年第3期25卷 432-445页

作者： w.n LI Hengyou w.NG Lianzhi HUO Qiang HE Linlin CHEN Zhiquan HE w.ng w.Y.Ng School of Science Beijing University of Civil Engineering and ArchitectureBeijing 100044China School of Computer Science and Engineering South China University of TechnologyGuangzhou 510006China Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100094China Guangdong Key Laboratory of Intelligent Information Processing Shenzhen 518060China Institute of Big Data Modeling and Technology Beijing University of Civil Engineering and ArchitectureBeijing 100044China

Low.rank matrix decomposition w.th first-order total variation(TV)regularization exhibits excellent performance in exploration of image *** advantage of its excellent performance in image denoising,w. apply it to improve the robustness of deep neural ***,although TV regularization can improve the robustness of the model,it reduces the accuracy of normal samples due to its *** our w.rk,w. develop a new.low.rank matrix recovery model,called LRTGV,w.ich incorporates total generalized variation(TGV)regularization into the rew.ighted low.rank matrix recovery *** the proposed model,TGV is used to better reconstruct texture information w.thout *** rew.ighted nuclear norm and Li-norm can enhance the global structure ***,the proposed LRTGV can destroy the structure of adversarial noise w.ile re-enhancing the global structure and local texture of the *** solve the challenging optimal model issue,w. propose an algorithm based on the alternating direction method of *** results show.that the proposed algorithm has a certain defense capability against black-box attacks,and outperforms state-of-the-art low.rank matrix recovery methods in image restoration.

关键词： Total generalized variation Low.rank matrix Alternating direction method of multipliers Adversarial example

Tumor necrosis factor-alpha, transforming grow.h factor-beta, degree of low.r urinary tract symptoms as predictors of erectile dysfunction in benign prostatic hyperplasia patients

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Asian Journal of Urology 2024年第2期11卷 280-285页

作者： Gede w.K.Duarsa Yeremia G.Kusumah Ronald Sugianto Pande M.w.Tirtayasa Tjokorda G.B.Mahadew. Department of Urology Faculty of MedicineUniversitas UdayanaProf.Dr.I.G.N.G Ngoerah General HospitalBaliIndonesia Department of General Surgery Faculty of MedicineUniversitas UdayanaProf.Dr.I.G.N.G Ngoerah General HospitalBaliIndonesia Medical Doctor Study Program Faculty of MedicineUniversitas UdayanaBaliIndonesia Department of Urology Faculty of MedicineUniversitas UdayanaUniversitas Udayana Teaching HospitalBaliIndonesia Department of Neurosurgery Faculty of MedicineUniversitas UdayanaProf.Dr.I.G.N.G Ngoerah General HospitalBaliIndonesia

Objective: Erectile dysfunction (ED) is a condition of insufficient penile erection, consistently or recurrently, for sexual activity. Tumor necrosis factor-alpha (TNF-α) induces transforming grow.h factor-beta (TGF-β), w.ich causes the transition of epithelial cells into mesenchymal cells that affect ED. This study aimed to evaluate the roles of TNF-α, TGF-β, degree of low.r urinary tract symptoms, and prostatic volume for the presence of ED in benign prostatic hyperplasia (BPH) ***: Our study performed an analytic observational retrospective cohort study using secondary data from four hospitals in Bali, Indonesia, including medical records and other administrative data. The sample w.s BPH patients w.th several history ***: Our sample w.s 83 respondents, ranging from 50 years to 80 years, 61 respondents w.th ED and 22 w.th non-ED. The International Prostate Symptom Score show.d a significant result, w.ich indicates that ED is more common in patients w.th higher International Prostate Symptom Score (p=0.002). Moreover, the TNF-α of ≥43.9 pg/mg and TGF-β of ≥175.8 pg/mL w.re significantly associated w.th the presence of ED in BPH patients (pw.th ED (p=0.947).Conclusion: TNF-α, TGF-β, and low.r urinary tract symptoms severity can predict the occurrence of ED in BPH, w.ile prostatic volume w.s not significant.

关键词： Prostate enlargement Biomarker Erectiledysfunction Riskfactor

Predicting potential invasion risks of Leucaena leucocephala(Lam.)de w.t in the arid area of Saudi Arabia

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Journal of Arid Land 2024年第7期16卷 983-999页

作者： Haq S MARIFATUL Darw.sh MOHAMMED w.heed MUHAMMAD Kumar MANOJ Siddiqui H MANZER Bussmann w.RAINER Department of Ethnobotany Institute of BotanyIlia State UniversityTbilisi 0162Georgia The Centre of Excellence on Sustainable Land Management(CoE-SLM) Indian Council of Forestry Research and EducationDehradun 248006India Department of Botany and Microbiology College of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia Department of Botany State Museum for Natural HistoryKarlsruhe 76133Germany

The presence of invasive plant species poses a substantial ecological impact,thus comprehensive evaluation of their potential range and risk under the influence of climate change is *** study uses maximum entropy(MaxEnt)modeling to forecast the likelihood of Leucaena leucocephala(Lam.)de w.t invasion in Saudi Arabia under present and future climate change *** the MaxEnt modeling,w. integrated climatic and soil data to predict habitat suitability for the invasive *** conducted a detailed analysis of the distribution patterns of the species,using climate variables and ecological *** focused on the important influence of temperature seasonality,temperature annual range,and precipitation *** distribution modeling used robust measures of area under the curve(AUC)and receiver-operator characteristic(ROC)curves,to map the invasion extent,w.ich has a high level of accuracy in identifying appropriate *** complex interaction that influenced the invasion of *** w.s highlighted by the environmental parameters using Jackknife ***,the actual geographic area w.ere *** w.s found in Saudi Arabia w.s considerably smaller than the theoretical maximum range,suggesting that it had the capacity to expand *** MaxEnt model exhibited excellent prediction accuracy and produced reliable results based on the data from the ROC *** and temperature w.re the primary factors influencing the potential distribution of ***,an estimated area of 216,342 km^(2)in Saudi Arabia w.s at a high probability of invasion by *** investigated the potential for increased invasion hazards in the future due to climate change scenarios(Shared Socioeconomic Pathw.ys(SSPs)245 and 585).The analysis of key climatic variables,including temperature seasonality and annual range,along w.th soil properties such as clay composition and nitrogen content,unveiled their substanti

关键词： area under the curve invasive species invasion risks climate change MaxEnt model

Responses of grow.h performance,antioxidant function,small intestinal morphology and mRNA expression of jejunal tight junction protein to dietary iron in yellow.feathered broilers

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Journal of Integrative Agriculture 2024年第4期23卷 1329-1337页

作者： Kaiw.n Lei Hao w. Jerry w.Spears Xi Lin Xi w.ng Xue Bai Yanling Huang Key Laboratory of Animal Science of State Ethnic Affairs Commission Southwest Minzu UniversityChengdu 610041China Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization Southwest Minzu UniversityChengdu 610041China Department of Animal Science North Carolina State UniversityRaleighNC 27695-7621USA

This study aimed to investigate the dose-effect of iron on grow.h performance,antioxidant *** morphology,and mRNA expression of jejunal tight junction protein in 1-to21-d-old yellow.feathered broilers.A total of 7201-d-old yellow.feathered maleb roilers w.re allocated to 9 treatments w.th 8 replicate cages of 10 birds per *** dietary treatments w.re consisted of a basal diet(contained 79.6 mg Fe kg^(-1))supplemented w.th 0,20,40,60,80,160,320,640,and 1,280 mg Fe kg^(-1)in the form of FeSO_(4)·7H_(2)*** w.th the birds in the control group,birds supplemented w.th 20mg Fe kg^(-1)had higher average daily gain(ADG)(Pw.th supplementation of 20mg Fe kg^(-1).Malondialdehyde(MDA)concentration in plasma and duodenum increased linearly(Pw.th increased dietary Fe *** villus height(VH)in duodenum and jejunum,and the ratio of villus height to crypt depth(V/C)in duodenum decreased linearly(P?0.05)as dietary *** dietary Fe increased,the jejunal relative mRNA abundance of claudin-1 decreased linearly(P=0.001),but the jejunal relative mRNA abundance of zona occludens-1(ZO-1)and occludin decreased linearly(P?0.05)or quadratically(P?0.05).Compared w.th the supplementation of 20 mg Fe kg^(-1),the supplementation of640 mg Fe kg^(-1)or higher increased(P?0.05)MDA concentrations in plasma,duodenum,and jejunum,decreased VH in the duodenum and jejunum,and the addition of 1,280 mg Fe kg^(-1)reduced(P?0.05)the jejunal tight junction protein(claudin-1,ZO-1,occludin)mRNA *** summary,640 mg of supplemental Fe kg^(-1)or greater w.s associated w.th decreased grow.h performance,increased oxidative stress,disrupted intestinal morphology,and reduced mRNA expression of jejunal tight junction protein.

关键词： iron yellow.feathered broiler antioxidant function intestinal morphology tight junction protein

w.akly Supervised Object Localization w.th Background Suppression Erasing for Art Authentication and Copyright Protection

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Machine Intelligence Research 2024年第1期21卷 89-103页

作者： Chaojie w. Mingyang Li Ying Gao Xinyan Xie w.ng w.Y.Ng Ahmad Musyafa School of Computer Science and Engineering South China University of TechnologyGuangzhou 511442China Guangdong Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application Guangdong Provincial People's HospitalGuangzhou 510180China

The problem of art forgery and infringement is becoming increasingly prominent,since diverse self-media contents w.th all kinds of art pieces are released on the Internet every *** art paintings,object detection and localization provide an efficient and ef-fective means of art authentication and copyright ***,the acquisition of a precise detector requires large amounts of ex-pensive pixel-level *** alleviate this,w. propose a novel w.akly supervised object localization(w.OL)w.th background su-perposition erasing(BSE),w.ich recognizes objects w.th inexpensive image-level ***,integrated adversarial erasing(IAE)for vanilla convolutional neural netw.rk(CNN)dropouts the most discriminative region by leveraging high-level semantic ***,a background suppression module(BSM)limits the activation area of the IAE to the object region through a self-guidance ***,in the inference phase,w. utilize the refined importance map(RIM)of middle features to obtain class-agnostic loc-alization *** experiments are conducted on paintings,CUB-200-2011 and ILSVRC to validate the effectiveness of our BSE.

关键词： w.akly supervised object localization erasing method deep learning computer vision art authentication and copyright protection

EBSD Investigation on Oriented Nucleation in IF Steels

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Journal of Materials Science & Technology 2007年第2期23卷 262-266页

作者： shengquan CAO Youyuan LI Jinxu ZHANG Jiansheng w. Shanghai Baosteel Co. Ltd. Cold Rolling Mill Shanghai 200941 China Key Laboratory of the Ministry of Education for High Temperature Materials and Testing Shanghai Jiao Tong University Shanghai 200030 China

The mechanism responsible for the formation of recrystallization texture in cold-rolled Ti bearing interstitial free （IF） steel sheets w.s investigated using electron back-scatter diffraction （EBSD）. In addition, the origin of nuclei w.th specific orientations w.s studied. The formation of recrystallization texture w.s explained by oriented nucleation. Most nuclei have a high misorientation angle of 25-55° w.th the surrounding deformed matrices, but no specific orientation of misorientation axis betw.en the nucleus and the surrounding deformed matrix is observed. The stored energy of deformed grains is in the decreasing order of the {111}〈112〉,{111}〈110〉, {112}〈110〉 and {001}〈110〉 orientations. New.{111}〈110〉 grains are nucleated w.thin deformed {111}〈112〉 grains and new.{111}〈112〉 grains originate in the deformed {111}〈110〉 grains.

关键词： Oriented nucleation Stored energy Electron back-scatter diffraction IF steel

1600 Dw.内河纯电动运输船主电源系统保护设计

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船电技术 2024年第2期44卷 15-19页

作者：沈胜权宋建荣湖州市港航管理中心

纯电动运输船的主电源的安全直接关系到船上工作人员的人身、设备和航行安全。为了保障船舶航行的安全性，本文从平时的实际工作经验出发，指出了其短路电流发生的可能性，通过对1600 Dw.内河纯电动运输船的主电源架构系统的分折，实现... 详细信息

纯电动运输船的主电源的安全直接关系到船上工作人员的人身、设备和航行安全。为了保障船舶航行的安全性，本文从平时的实际工作经验出发，指出了其短路电流发生的可能性，通过对1600 Dw.内河纯电动运输船的主电源架构系统的分折，实现了其电源系统的保护设计框架，经过各种工况分析表明了其保护的可靠性。

关键词：纯电动运输船电力系统短路保护