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Chinese Journal of Chemistry 1996年第4期14卷 315-320页

作者： Zang, L shen, t CHINESE ACAD SCI INST PHOTOG CHEMBEIJING 100101PEOPLES R CHINA

the optical effects of the adsorption of eosin on the colloidal sliver particle have been investigated in aqueous solutions. It was found that upon adsorption the fluorescence of eosin was effectively quenched. this was explained as the photoinduced interfacial electron transfer from the excited singlet state of eosin to the silver particle. Decreasing pH of the solution favors the adsorption of eosin and so enhances the fluorescence quenching. For comparison, the fluorescence quenching in reverse micelles was also investigated. the quenching behavior was much different from that mediated in aqueous solution. this was attributed to the unique microenvironment of reverse micelles.

关键词： photoinduced electron transfer eosin reverse micelle

Synthesis of demethoxy-amino-substituted hypocrellins: novel photosensitizers for photodynamic therapy

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Chinese Chemical Letters 2000年第11期11卷 963-966页

作者： Wu, t Xu, SJ shen, JQ Chen, S Zhang, MH shen, t Chinese Acad Sci Inst Chem Ctr Mol Sci Beijing 100080 Peoples R China

A novel method was used to obtain demethoxy-amino-substituted hypocrellin derivatives. Peri-hydroxylated perylenequinone structure of hypocrellin was reserved when hypocrellin reacted with an amine in pyridine. the products were new compounds with significant cytoxicity against tumor cells. their structures have been established on the basis of their mass and H-1 NMR spectra.

关键词： Synthesis of demethoxy-amino-substituted hypocrellins novel photosensitizers for photodynamic therapy

Advances in dye-sensitized solar cell

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Chinese Science Bulletin 1997年第23期42卷 1937-1948页

作者： Jing, BW Zhang, MH shen, t Chinese Acad Sci Inst Photog Chem Beijing 100101 Peoples R China

tHE conversion of visible light to electricity using semiconductors as light absorbers has beenan important area of research for many years. In the 1970s, highly efficient photovoltaiccells based on silicon were developed (the light-to-electrical conversion efficiency≥25%),which provides energy to aircrafts. then semiconductor liquid-junction photoelectrochemicalcell started to be investigated. Generally speaking, highly efficient liquid-junction photoelec-trochemical solar cells can be obtained by using semiconductors such as Si, GaAs and WSe.(band gap≈(1.3±0.3) eV). Conversion efficiencies over 15% have been acquired on solarcells consisting of single crystals of Si or GaAs. But the serious photocorrosion and high

关键词： dye-sensitized solar cell ruthenium complex.

COMPARISON OF tHREE MEtHODS tO PREDICt ADSORPtION ISOtHERMS FOR ORGANIC VAPORS FROM SIMILAR AND NON-SIMILAR POLARItY REFERENCE VAPORS

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Chinese Journal of Chemical Engineering 1989年第2期 298-308页

作者：汪大翚 t.shen Kenneth E.Noll Department of Chemical Engineering Zhejiang University Hangzhou Department of Environmental Engineering Illinois Institute of Techmology Chicago IL 60616 U.S.A.

the Polanyi-Dubinin equation was used to predict adsorption isotherms for eight organic vapors at 25℃ and for two organic vapors at 25℃, 40℃ and 60℃ on activated carbon in this analysis. the theoretical affinity coefficient, β, was calculated by three methods (molar volume, molecular parachor and electronic polarization) based on nonpolar and polar reference vapors.

关键词： isotherms affinity molar Polar deviation polar monitored adsorbed maintained beads

Systematic review with meta-analysis on transplantation for alcohol-related liver disease:Very low evidence of improved outcomes

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World Journal of Gastroenterology 2019年第13期25卷 1628-1639页

作者： Nicole t shen Cristina Londono Stephanie Gold Ashley Wu Keith C Mages Robert S Jr Brown Department of Medicine Division of Gastroenterology and Hepatology Weill Cornell Medicine New York Department of Medicine Weill Cornell Medical College New York Department of Medicine Division of Internal Medicine Weill Cornell Medicine New York Department of Medicine Weill Cornell Medical College Samuel J. Wood Library and C.V. Starr Biomedical Information Center New York

BACKGROUND Alcohol-related liver disease(ALD) is a leading cause of liver failure and indication for liver transplantation that arises in the setting of alcohol use disorder(AUD). Previous reviews of transplantation for ALD are limited in scope of outcomes and type of ALD studied. A comprehensive systematic review could improve use of transplantation in ALD and improve future research. We hypothesize that while transplanting ALD may improve mortality and relapse,findings will be limited by pre-specified causes of heterogeneity-assessment and treatment of AUD, definition of ALD, spectrum of ALD studied, assessment and rates of relapse, and study quality and *** to optimize liver transplantation for ALD, understanding existing research to guide future research, we conducted a systematic review with *** We conducted a systematic review, comparing liver transplant to no-transplant in patients with ALD, with a primary outcome of both short-and long-term mortality and relapse. We performed a comprehensive search of MEDLINE,EMBASE, Web of Science, and the Cochrane Library databases for peer-reviewed journal articles comparing use of liver transplant in ALD to no-transplant. two reviewers independently conducted screening, full text review, and data extraction according to the PRISMA guidelines. We report the quality of the evidence according to the GRADE *** We analyzed data from 10 studies. Of 1332 participants, 34.2%(456/1332) had undergone liver transplantation, while 65.8%(876/1332) had not. While random effects meta-analysis suggested transplant in comparison to no-transplant had an association of reduced mortality that did not reach statistical significance, relative risk(RR) = 0.51(0.25-1.05), but not relapse risk, RR = 0.52(0.18-1.53), significant heterogeneity limited these findings. When restricted to prospective data,transplant compared to no-transplant significantly reduced mortality, RR = 0.25(0.13-0.46, P < 0.01), and relap

关键词： Alcohol-related hepatitis Alcohol-related cirrhosis Alcohol use disorder Liver transplantation Standardization

the electrical switching characteristics of single copper tetra-cyanoquinodimethane nanowire

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Nano-Micro Letters 2009年第1期1卷 23-26页

作者： K.B.Zheng H.t.shen C.N.Ye J.L.Li D.L.Sun G.R.Chen Department of Materials Science Fudan University Department of Materials Science and Engineering Soochow University

In this paper, method combined vapor transportation with in-situ chemical reaction is employed to synthesize Cu(tCNQ) nanowires. the typical diameter of nanowires is 50-500 nm with high uniformity. the electrical switching characteristics of single nanowire are observed. the ON-OFF resistance ratio for switching reaches 10~4. the investigation reveals a linear relationship between the switching threshold and the spacing between the two electrodes. the temporal response of the switching process is 30 ns and the switch exhibits good reproducibility. the collapse of the nanowire under the condition of current surge is also discussed. It is believed that the Cu(tCNQ) nanowire could be promising for applications in nanoelectronics.

关键词： Cu(tCNQ) Nanowire Electrical switching Charge transfer Complexes

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活性炭上吸附平衡的三种预测方法比较

化工学报 1989年第6期40卷 655-663页

作者：汪大翚 t.shen Kenneth E.Noll 浙江大学化工系伊里诺斯理工学院环境工程系

在用三种方法(摩尔体积、分子等张比容及摩尔电子极化度)计算亲和系数β的基础上,用polanyi-Dubinin方程预计了25℃下八种有机蒸汽以及25、40和60℃下另两种有机蒸气在活性炭上的吸附等温线.相应的实验数据用重量法测定.预计的和实验的... 详细信息

在用三种方法(摩尔体积、分子等张比容及摩尔电子极化度)计算亲和系数β的基础上,用polanyi-Dubinin方程预计了25℃下八种有机蒸汽以及25、40和60℃下另两种有机蒸气在活性炭上的吸附等温线.相应的实验数据用重量法测定.预计的和实验的数据对比表明:(1)对于优化的预计,参照物应与被预计吸附质有相似的极性;(2)选择适宜的参照物后,三种预计方法在精度上无明显差异;(3)对不同温度下的预计,摩尔体积法更为简便、实用.

关键词：活性炭吸附平衡预测法

牛疱疹病毒Ⅳ型(DN-599株)DNA的限制性酶切位点图及重复序列分析

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病毒学报 1990年第2期6卷 160-166页

作者：童光志 Dieter Burger David t.shen 中国农业科学院哈尔滨兽医研究所美国华盛顿州立大学USDA-ARS实验室

牛疱疹病毒Ⅳ型(BHV-4)DNA片段分别被重组到质粒pUC9或pBR322的EcoRI、Hind Ⅲ和BamHⅠ位点中,用光生物素(Photobiotin)标记这些重组质粒作为探针,分别与转移到硝基纤维素膜上的病毒DNA的EcoRⅠ、Hind Ⅲ和BamHⅠ片段进行杂交,根据杂交... 详细信息

牛疱疹病毒Ⅳ型(BHV-4)DNA片段分别被重组到质粒pUC9或pBR322的EcoRI、Hind Ⅲ和BamHⅠ位点中,用光生物素(Photobiotin)标记这些重组质粒作为探针,分别与转移到硝基纤维素膜上的病毒DNA的EcoRⅠ、Hind Ⅲ和BamHⅠ片段进行杂交,根据杂交结果及克隆的BHV-4DNA片段的双酶切分析,画出了病毒DNA的EcoRⅠ、Hind Ⅲ和BamHⅠ位点图,井证明在病毒DNA的两末端含有多聚重复序列,左侧含12个重复单位,右侧含6个重复单位,两侧重复单位的排列方向相同,重复单位的大小为2.35kb。病毒DNA分子无任何异构体.

关键词：牛疱疹病毒酶位点图重复序列

牛疱疹病毒Ⅳ型(DN-599株)DNA的分子克隆

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病毒学杂志 1990年第4期4卷 423-429页

作者：童光志 Dieter Burger David t shen 中国农业科学院哈尔滨兽医研究所哈尔滨150001 美国华盛顿州立大学USDA-ARS 实验室

从感染的MDBK(牛肾)细胞中直接抽提出牛疱疹病毒IV型(BHV-4)DNA。分别经限制性内切酶EcoRⅠ,HindⅢ或BamHI消化后,用鸟枪法和选择法将病毒DNA片段克隆到质粒pBR322和pUC9的相应位点中,构建了三组病毒DNA基因库。阳性克隆是用光生物素标... 详细信息

从感染的MDBK(牛肾)细胞中直接抽提出牛疱疹病毒IV型(BHV-4)DNA。分别经限制性内切酶EcoRⅠ,HindⅢ或BamHI消化后,用鸟枪法和选择法将病毒DNA片段克隆到质粒pBR322和pUC9的相应位点中,构建了三组病毒DNA基因库。阳性克隆是用光生物素标记的病毒DNA和牛胸腺细胞DNA与各重组质粒DNA杂交而筛选的。总共克隆了病毒基因组的94％,其中用EcoRI克隆了83.4％,BamHI克隆了63.4％,HindIlI克隆了45％。

关键词：牛疱疹病毒 IV型分子克隆

23项生物产业研究动向值得关注 CNS亮点研究成果细盘点

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中国战略新兴产业 2016年第5期 32-37页

作者： t.shen

Cell、Nature和Science(CNS)是国际上代表生命科学最高水平的三大学术杂志。2015年三大杂志刊登了很多耐人寻味的研究,对于人类抗击癌症、艾滋病等医疗工作有着重要意义。编辑部摘编了一些研究成果亮点,希望从中一窥未来生物产业发展的... 详细信息

Cell、Nature和Science(CNS)是国际上代表生命科学最高水平的三大学术杂志。2015年三大杂志刊登了很多耐人寻味的研究,对于人类抗击癌症、艾滋病等医疗工作有着重要意义。编辑部摘编了一些研究成果亮点,希望从中一窥未来生物产业发展的新方向。

关键词：生物产业 Cell 造血干细胞脐带血骨髓细胞 HIV 星形细胞瘤重度抑郁症肿瘤复发候选疫苗衣壳蛋白研究者人类免疫缺陷病毒打印技术 Nature 胰腺肿瘤胰腺癌 CNS