Synthesis of demethoxy-amino-substituted hypocrellins: novel photosensitizers for photodynamic therapy
Synthesis of demethoxy-amino-substituted hypocrellins: novel photosensitizers for photodynamic therapy作者机构：Center for Molecular Science Institute of Chemistry Chinese Academy of Science Beijing 100080 China
出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)
年 卷 期：2000年第11卷第11期
页 面：963-966页
核心收录：
基 金：the National Natural Science Foundation of China. (No. 29772035 and 29872038)
主 题：Synthesis of demethoxy-amino-substituted hypocrellins novel photosensitizers for photodynamic therapy
摘 要：A novel method was used to obtain demethoxy-amino-substituted hypocrellin derivatives. Peri-hydroxylated perylenequinone structure of hypocrellin was reserved when hypocrellin reacted with an amine in pyridine. The products were new compounds with significant cytotoxicity against tumor cells. Their structures have been established on the basis of their mass and 1H NMR spectra.
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