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Lipid metabolism-related long noncoding RNA RP11-817I4.1 promotes fatty acid synthesis and tumor progression in hepatocellular carcinoma

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World Journal of Gastroenterology 2024年第8期30卷 919-942页

作者： Ren-Yong Wang Jia-Ling Yang Ning xu Jia xu shao-Hua Yang Dao-Ming Liang Jin-Ze Li Hong Zhu Second Affiliated Hospital of Kunming Medical University Kunming 650106Yunnan ProvinceChina School of Basic Medical Sciences Nanjing Medical UniversityNanjing 211166Jiangsu ProvinceChina Wuhan Blood Center Wuhan 430030Hubei ProvinceChina Department of Gastrointestinal Surgery The Third People's Hospital of Hubei ProvinceWuhan 430071Hubei ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)is one of the most common types of *** influence of lipid metabolism disruption on the development of HCC has been demonstrated in published *** To establish an HCC prognostic model for lipid metabolism-related long non-coding RNAs(LMR-lncRNAs)and conduct in-depth research on the specific role of novel LMR-lncRNAs in *** Correlation and differential expression analyses of The Cancer Genome Atlas data were used to identify differentially expressed *** real-time polymerase chain reaction analysis was used to evaluate the expression of *** red staining was employed to observe intracellular lipid *** interaction between RP11-817I4.1,miR-3120-3p,and ATP citrate lyase(ACLY)was validated through the performance of dual-luciferase reporter gene and RIP *** Three LMR-lncRNAs(negative regulator of antiviral response,RNA transmembrane and coiled-coil domain family 1 antisense RNA 1,and RP11-817I4.1)were identified as predictive markers for HCC patients and were utilized in the construction of risk ***,proliferation,migration,and invasion were reduced by RP11-817I4.1 *** increase in lipid levels in HCC cells was significantly induced by RP11-817I4.1 through the miR-3120-3p/ACLY *** LMR-lncRNAs have the capacity to predict the clinical characteristics and prognoses of HCC patients,and the discovery of a novel LMR-lncRNAs,RP11-817I4.1,revealed its role in promoting lipid accumulation,thereby accelerating the onset and progression of HCC.

关键词： Hepatocellular carcinoma Lipid metabolism Immune microenvironment Prognostic markers Metabolic reprogramming

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Enhancing electromagnetic wave absorption with core‐shell structured SiO_(2)@MXene@MoS_(2)nanospheres

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Carbon Energy 2024年第8期6卷 90-104页

作者： xuewen Jiang Qian Wang Limeng Song Hongxia Lu Hongliang xu Gang shao Hailong Wang Rui Zhang Changan Wang Bingbing Fan School of Material Science and Engineering Zhengzhou UniversityZhengzhouHenanChina Henan Key Laboratory of Aeronautical Materials and Application Technology School of Material Science and EngineeringZhengzhou University of AeronauticsZhengzhouHenanChina School of Materials Science and Engineering Tsinghua UniversityBeijingChina

Material composition and structural design are important factors influencing the electromagnetic wave(EMW)absorption performance of *** alleviate the impedance mismatch attributed to the high dielectric constant of Ti_(3)C_(2)T_(x)MXene,we have successfully synthesized core‐shell structured SiO_(2)@MXene@MoS_(2)*** architecture,comprising SiO_(2)as the core,MXene as the intermediate layer,and MoS_(2)as the outer shell,is achieved through an electrostatic self‐assembly method combined with a hydrothermal *** complex core‐shell structure not only provides a variety of loss mechanisms that effectively dissipate electromagnetic energy but also prevents self‐aggregation of MXene and MoS_(2)***,the synergistic combination of SiO_(2)and MoS_(2)with highly conductive MXene enables the suitable dielectric constant of the composites,ensuring optimal impedance ***,the core‐shell structured SiO_(2)@MXene@MoS_(2)nanospheres exhibit excellent EMW absorption performance,featuring a remarkable minimum reflection loss(RL_(min))of−52.11 dB(2.4 mm).It is noteworthy that these nanospheres achieve an ultra‐wide effective absorption bandwidth(EAB)of 6.72 *** work provides a novel approach for designing and synthesizing high‐performance EMW absorbers characterized by“wide bandwidth and strong reflection loss.”

关键词： core‐shell structure electromagnetic wave absorption multiloss mechanism SiO_(2)@MXene@MoS_(2)

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Removal of rubidium from brine by an integrated film of sulfonated polysulfone/graphene/potassium copper ferricyanide

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Chinese Journal of Chemical Engineering 2024年第5期69卷 112-121页

作者： Huanxi xu Peihua Lin Pei-jun Liu Hai-Gang Liu Hui-Bin Guo Chao-Xiang Wu Ming Fang xu Zhang Guan-Ping Jin Anhui Province Engineering Research Center of Flexible and Intelligent Materials School of Chemistry and Chemical EngineeringHefei University of TechnologyHefei 230009China Chemical Design and Research Institute Co. LTD of Qinghai ProvinceQinghai Engineering and Technology Research Center of Fine ChemicalXining 810008China

A novel integrated film of sulfonated polysulfone/graphene/potassium copper ferricyanide(KCuFC/SPSG)was used for selectively extracting rubidium ion(Rb^(+))from *** form KCuFC/SPSG,the precursor film of sulfonated polysulfone/graphene(SPSG)was synthesized by phase conversion process,which was alternately immersed in 0.1 mol·L^(-1)CuSO_(4)/K_(4)[Fe(CN)_(6)]by in-situ adsorption coupled co-precipitation *** data such as nuclear magnetic resonance spectrometer,Fourier transform infrared spectroscope,X-ray photoelectron spectroscope,X-ray diffraction,scanning electron microscope,and energy dispersive spectroscopy all verified that abundant KCuFC were uniformly located on the *** resulting KCuFC/SPSG was used in film separation *** the solution was fed into the system,the Rb^(+)could be selectively adsorption by KCuFC/*** the saturation adsorption,0.5 mol·L^(-1)NH_(4)Cl/HCl was fed into the film cell,Rb^(+)could be quickly desorbed by ion-exchange between Rb^(+)and NH_(4)^(+)in the lattice of *** purpose of separating and recovering Rb^(+)from the brine can be achieved after the repeated *** effects of pH,adsorption time,and interferential ions on the adsorption capacity of Rb^(+)were investigated by batch *** adsorption behavior fits the pseudo-second order kinetic process,while KCuFC has a higher adsorption capacity(Langmuir maximum sorption 165.4 mg·g^(-1)).In addition,KCuFC/SPSG shows excellent selectivity for Rb^(+)even in complex brine ***/SPSG could maintain 93.5%extraction efficiency after five adsorption/desorption cycles.

关键词： Rubidium extraction Potassium copper ferricyanide Sulfonated polysulfone Graphene oxide Adsorption

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Tough Semi-interpenetrating Polyvinylpyrrolidone/Polyacrylamide Hydrogels Enabled by Bioinspired Hydrogen-bonding Induced Phase Separation

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Chinese Journal of Polymer Science 2024年第5期42卷 591-603,I0006页

作者： Qiong-jun xu Zhao-Yang Yuan Chang-Cheng Wang Hao Liang Yu Shi Hai-Tao Wu Hu xu Jing Zheng Jin-Rong Wu State Key Laboratory of Polymer Materials Engineering College of Polymer Science and EngineeringSichuan UniversityChengdu610065China

Semi-interpenetrating(semi-IPN)hydrogels formed by the continuous interpenetration of cross-linked polymer network and linear non-crosslinked polymer with multifunctionality are widely used in biomedical and other ***,the negative impact of linear polymer on the homogeneity of the cross-linked network often leads to a decrease in the mechanical properties of semi-IPN hydrogels and severely limits their ***,a bioinspired hydrogen-bonding induced phase separation strategy is presented to construct the tough semi-IPN polyvinylpyrrolidone/polyacrylamide hydrogels(named PVP/PAM hydrogels),including the linear polymer polyvinylpyrrolidone(PVP)and cross-linked polyacrylamide(PAM)*** resultant PVPx/PAM hydrogels exhibit unique phase separation induced by the hydrogen bonding between PVP and PAM and affected by the amount of substance of ***,the phase separation of PVPx/PAM hydrogels results in excellent mechanical properties with a strain of 2590%,tensile strength of 0.28 MPa and toughness of 2.17 MJ/m^(3).More importantly,the hydrogen bonding between PVP and PAM firstly disrupts to dissipate energy under external forces,so the PVPx/PAM hydrogels exhibit good self-recovery properties and outperform chemically cross-linked PAM hydrogels in impact resistance and damping *** is believed that the PVPx/PAM hydrogels with hydrogen-bonding induced phase separation possess more potential application prospects.

关键词： Tough Semi-interpenetrating networks Polyvinylpyrrolidone/polyacrylamide Hydrogels Phase separation

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Wafer-scale synthesis of twodimensional materials for integrated electronics

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Chip 2024年第1期3卷 64-83页

作者： Zijia Liu xunguo Gong Jinran Cheng Lei shao Chunshui Wang Jian Jiang Ruiqing Cheng jun He Key Laboratory of Artificial Micro-and Nano-structures of Ministry of Education and School of Physics and TechnologyWuhan UniversityWuhan 430072China Wuhan Guide Infrared Co. Ltd.Wuhan 430200China Global Sensor Technology Wuhan 430200China

Two-dimensional(2D)van derWaals materials have attracted great interest and facilitated the development of post-Moore electronics owing to their novel physical properties and high compatibility with traditional microfabrication *** wafer-scale synthesis has become a critical challenge for large-scale integrated *** the wafer-scale synthesis approaches for some 2D materials have been extensively explored,the preparation of high-quality thin films with well-controlled thickness remains a big *** review focuses on the wafer-scale synthesis of 2D materials and their applications in integrated ***,several representative 2D layered materials including their crystal structures and unique electronic properties were ***,the current synthesis strategies of 2Dlayeredmaterials at thewafer scale,which are divided into“top-down”and“bottom-up”,were reviewed in ***,the applications of 2D materials wafer in integrated electrical and optoelectronic devices were ***,the current challenges and future prospects for 2D integrated electronics were *** is hoped that this reviewwill provide comprehensive and insightful guidance for the development of wafer-scale 2D materials and their integrated applications.

关键词： 2D materials Wafer-scale synthesis 2D integrated devices Post-moore electronics

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The Non-inclusion Diagnosability of Hypercubes Under the PMC Model

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Journal of the Operations Research Society of China 2024年第2期12卷 478-484页

作者： Mei-Jie Ma Min xu Tong-Tong Ding Xiang-jun Li Qiang Zhu School of Mathematics and Statistics Qilu University of Technology(Shandong Academy of Sciences)Jinan 250353ShandongChina School of Mathematical Sciences Beijing Normal UniversityLaboratory of Mathematics and Complex SystemsMinistry of EducationBeijing 100875China School of Information and Mathematics Yangtze UniversityJingzhou 434023HubeiChina School of Mathematics and Statistics XiDian UniversityXi'an 710071ShaanXiChina

Diagnosability of a multiprocessor system is an important measure of the reliability of interconnection ***-level diagnosis is a primary strategy to identify the faulty processors in a multiprocessor *** on a sound assumption proposed by Zhu et ***,we proposed a new diagnosability named non-inclusion diagnosability and showed that the non-inclusion diagnosability t_(N)(Q_(n))of the hypercube under the PMC model is *** is,assume that if two vertex sets F_(1) and F_(2) are both consistent with a syndrome and F_(1)C F_(2),then F_(2) is not the faulty set which we are looking for;the faulty set F is 1-step diagnosable if|F|≤2n-2 in Q_(n) under the PMC model.

关键词： Interconnection network Diagnosability Hypercube PMC model

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Is deep brain imaging on the brink of transformation with a bioluminescence molecule?

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BMEMat(BioMedical Engineering Materials) 2024年第3期2卷 4-8页

作者： Shumao xu Farid Manshaii jun Chen Department of Bioengineering University of CaliforniaLos AngelesLos AngelesUSA

Cephalofurimazine(CFz),when paired with Antares luciferase,shows superior blood-brain barrier permeability and enhanced imaging depth and clarity for deep brain *** bioluminescence provides a less invasive method for real-time monitoring of deep brain activity,with the potential to advance targeted therapies and deepen our understanding of brain *** molecular engineering and localized delivery can reduce the potential toxicity of CFz and enhance its efficacy for clinical deep brain imaging.

关键词： bioluminescence molecule blood-brain barrier brain imaging

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Leveraging the Empirical Wavelet Transform in Combination with Convolutional LSTM Neural Networks to Enhance the Accuracy of Polar Motion Prediction

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Research in Astronomy and Astrophysics 2024年第9期24卷 214-224页

作者： xu-Qiao Wang Lan Du Zhong-Kai Zhang Ze-jun Liu Hao Xiang College of Geospatial Information Information Engineering UniversityZhengzhou 450001China Henan Industrial Technology Academy of Spatio-Temporal Big Data Zhengzhou 450046China

High-precision polar motion prediction is of great significance for deep space exploration and satellite *** motion is affected by a variety of excitation factors,and nonlinear prediction methods are more suitable for polar motion *** order to explore the effect of deep learning in polar motion *** paper proposes a combined model based on empirical wavelet transform(EWT),Convolutional Neural Networks(CNN)and Long Short Term Memory(LSTM).By training and forecasting EOP 20C04 data,the effectiveness of the algorithm is verified,and the performance of two forecasting strategies in deep learning for polar motion prediction is *** results indicate that recursive multi-step prediction performs better than direct multi-step prediction for short-term forecasts within 15 days,while direct multi-step prediction is more suitable for medium and long-term *** the 365 days forecast,the mean absolute error of EWT-CNN-LSTM in the X direction and Y direction is 18.25 mas and 15.78 mas,respectively,which is 23.5% and 16.2% higher than the accuracy of Bulletin *** results show that the algorithm has a good effect in medium and long term polar motion prediction.

关键词： data analysis methods:miscellaneous astrometry reference systems Earth

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Damping capacity of Fe_(83)Ga_(17) magnetostrictive alloy under magnetic field

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Rare Metals 2024年第1期43卷 402-409页

作者： shao-Wen Yan Xing Mu Bing-Jie Liu Li-Hong xu Shi-Hai Guo Yan Qi Hong-Ping Zhang Department of Functional Material Research Central Iron and Steel Research InstituteBeijing 100081China

The damping performance of Fe_(83)Ga_(17) alloys has been investigated in the static magnetic field (H). The results demonstrate that the damping peak value can be adjusted between 0.020 and 0.085 under the magnetic f... 详细信息

关键词： alloy magnetic alloys

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Multifunctional interfacial molecular bridge enabled by an aggregation-induced emission strategy for enhancing efficiency and UV stability of perovskite solar cells

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Journal of Energy Chemistry 2024年第8期95卷 588-595,I0013页

作者： Shuhang Bian Yuqi Wang Fancong Zeng Zhongqi Liu Bin Liu Yanjie Wu Long shao Yongzhi shao Huan Zhang Shuainan Liu Jin Liang xue Bai Lin xu Donglei Zhou Biao Dong Hongwei Song State Key Laboratory on Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012JilinChina College of Science Shanghai UniversityShanghai 200444China

The interface defects between the electron transport layer(ETL)and the perovskite layer,as well as the low ultraviolet(UV)light utilization rate of the perovskite absorption layer,pose significant challenges for the commercialization of perovskite solar cells(PSCs).To address this issue,this paper proposes an innovative multifunctional interface modulation strategy by introducing aggregation-induced emission(AIE)molecule 5-[4-[1,2,2-tri[4-(3,5-dicarboxyphenyl)phenyl]ethylene]phenyl]benzene-1,3-dicarboxylic acid(H_(8)ETTB)at the SnO_(2)ETL/perovskite ***,the interaction of H_(8)ETTB with the SnO_(2)surface,facilitated by its carboxyl groups,is effective in passivating surface defects caused by noncoord inated Sn and O *** interaction enhances the conductivity of the SnO_(2)film and adjusts energy levels,leading to enhanced charge carrier ***,H_(8)ETTB can passivate noncoord inated Pb^(2+)ions at the perovskite interface,promoting perovskite crystallization and reducing the interface energy barrier,resulting in a perovskite film with low defects and high crystalline *** importantly,the H_(8)ETTB molecule,can convert UV light into light absorbable by the perovskite,thereby reducing damage caused by UV light and improving the device's utilization of ***,the champion PSC based on SnO_(2)-H_(8)ETTB achieves an impressing efficiency of 23.32%and significantly improved photostability compared with the control device after continuous exposure to intense UV *** addition,the Cs_(0.05)(FA_(0.95)MA_(0.05))_(0.95)Pb(I_(0.95)Br_(0.05))_(3)based device can achieve maximum efficiency of 24.01%,demonstrating the effectiveness and universality of this ***,this innovative interface bridging strategy effectively tackles interface defects and low UV light utilization in PSCs,presenting a promising approach for achieving highly efficient and stable PSCs.

关键词： Perovskite solar cells Aggregation-induced emission Defect passivation Efficiency UV stability

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