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How do project-oriented organizations enhance innovation?An institutional theory perspective

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Frontiers of Engineering Management 2023年第3期10卷 427-438页

作者： shankar SANKARAN Catherine PKILLEN Alexandra PITSIS Faculty of Design Architecture and Building University of Technology SydneyUltimoNSW 2007Australia

A project-oriented organization is a hybrid form of organization where a functional hierarchy is augmented with structures to manage projects strategically across the *** project-oriented organizations from diverse industries that emphasize innovation in their strategies were selected for this *** use the three pillars of institutional theory—regulative,normative and cultural-cognitive—and institutional entrepreneurship to analyze interview data from executive and project,program and portfolio management personnel in the project-oriented organizations to investigate how innovation is facilitated through external influences and internal *** findings indicate that processes and new structures provide effective ways for innovation and,while individuals are important,processes are more effective than individuals at enabling *** put forward some lessons for practice that emerge directly from the findings,including suggestions on improving allocation of resources,a need to focus on processes,reconceptualization of“failure”,and dedicated investment in market knowledge,customer knowledge,performance metrics and flexible governance structures.

关键词： project-oriented organizations innovation institutional entrepreneurship institutional theory

Detoxication and Theranostic Aspects of Biosynthesised Zinc Oxide Nanoparticles for Drug Delivery

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Acta Metallurgica Sinica(English Letters) 2021年第5期34卷 729-740页

作者： Krishnaswamy Kanagamani Pitchaipillai Muthukrishnan Ayyasami Kathiresan Karikalan shankar Pandurengan Sakthivel Murugan Ilayaraja Department of Chemistry SNS College of TechnologyCoimbatore641035India Department of Chemistry Faculty of EngineeringKarpagam Academy of Higher EducationCoimbatore641021India Department of Physics Faculty of EngineeringKarpagam Academy of Higher EducationCoimbatore641021India Department of Chemistry Arumugam Pillai Seethai Ammal CollegeTirupattur630211India

Bioactive materials obtained from plant bio-resources offer immense attention for development and production of nanotechnology enabled products for biomedical *** the present study,Ficus hispida leaf extract(FHLE)was used as a stabilising agent for the environmentally benign synthesis of zinc oxide nanoparticles(ZnO-NPs)which were investigated for prospective versatile applications(anticancer and photocatalytic activities).The formation of ZnO-NPs was confirmed by UV–visible ***(hexagonal)form of the herb-assisted synthesised ZnO-NPs with particle size ranging from 20 to 200 nm was confirmed by transmission electron microscopy(TEM)*** vitro analysis was carried out against Dalton's lymphoma ascites(DLA)cell lines by trypan blue assay,the results revealed 96%inhibition at concentration of 200μg ml-1,and the photodegradation experiments carried out for degradation of Congo red revealed complete degradation of the dye after 70 min of exposure to UV light.

关键词： Zinc oxide nanoparticles Anticancer activity Photocatalysis Congo red

Reconstruction of Pathways Associated with Amino Acid Metabolism in Human Mitochondria

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Genomics, Proteomics & Bioinformatics 2007年第3期5卷 166-176页

作者： Purnima Guda Chittibabu Guda shankar Subramaniam Gen *NY* sis Center for Excellence in Cancer Genomics and Department of Epidemiology and Biostatistics State University of New York at AlbanyRensselaerNY 12144-3456USA San Diego Supercomputer Center University of California at San DiegoLa JollaCA 92093-0505USA Departments of BioengineeringChemistry and BiochemistryUniversity of California at San DiegoLa JollaCA 92093USA.

We have used a bioinformatics approach for the identification and reconstruction of metabolic pathways associated with amino acid metabolism in human mitochondria. Human mitochondrial proteins determined by experimental and computational methods have been superposed on the reference pathways from the KEGG database to identify mitochondrial pathways. Enzymes at the entry and exit points for each reconstructed pathway were identified, and mitochondrial solute carrier proteins were determined where applicable. Intermediate enzymes in the mitochondrial pathways were identified based on the annotations available from public databases, evidence in current literature, or our MITOPRED program, which predicts the mitochondrial localization of proteins. Through integration of the data derived from experimental, bibliographical, and computational sources, we reconstructed the amino acid metabolic pathways in human mitochondria, which could help better understand the mitochondrial metabolism and its role in human health.

关键词： mitochondria metabolic pathways amino acid metabolism human

Heat transfer attributes of Al_(2)O_(3)-Fe_(3)O_(4)/H_(2)O hybrid nanofluid flow over a yawed cylinder

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Propulsion and Power Research 2022年第3期11卷 416-429页

作者： P.M.Patil H.F.shankar Department of Mathematics KLE Technological UniversityB V Bhoomaraddi CampusVidyanagarHubballi-580031India Department of Mathematics Karnatak UniversityPavate NagarDharawad-580003India

Flow over yawed and unyawed blunt bodies often occurs in various engineeringapplications. The fluid flow over a yawed cylinder explains the practical significance of subseaapplications such as transference control, separating the boundary layer above submergedblocks, and suppressing recirculating bubbles. The current study uses viscous dissipation toanalyze the mixed convective hybrid nanofluid flow around a yawed cylinder. Unlike the stan-dard nanofluid model, which only considers one type of nanoparticle, this work considers thehybridization of two types of nanoparticles: alumina (Al_(2)O_(3)) and magnetite (Fe_(3)O_(4)). A modelwas developed to investigate the heat transport behaviour of a hybrid nanofluid while account-ing for the solid volume fraction. The flow problem is modelled in terms of highly nonlinearpartial differential equations (NPDEs) subject to the appropriate boundary conditions. Thenappropriate non-similar transformations were used to non-dimensionalize the governing equa-tions. Furthermore, the non-dimensional governing equations were solved using the finite dif-ference method (FDM) and the quasilinearisation technique. The effects of water andnanoparticle concentrations on the velocity and the temperature patterns were illustrated graph-ically. The hybrid nanofluid reduces the velocity distribution in the spanwise and chordwise di-rections while increasing the surface drag coefficient. The hybrid nanofluid’s fluid temperatureand energy transport strength was higher than the base fluid and nanofluid. Also, the temper-ature of the fluid rises as the energy transfer strength diminishes due to an increase in the Eckert number, which characterizes viscous dissipation. However, when the yaw angle increases in thechordwise and spanwise directions, so does the fluid’s velocity. The new outcomes werecompared to previously published research and were in good agreement.

关键词： Yawed cylinder Mixed convection Hybrid nanofluid Eckert number Finite difference method

An IoT-Cloud Based Intelligent Computer-Aided Diagnosis of Diabetic Retinopathy Stage Classification Using Deep Learning Approach

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Computers, Materials & Continua 2021年第2期66卷 1665-1680页

作者： K.shankar Eswaran Perumal Mohamed Elhoseny Phong Thanh Nguyen Department of Computer Applications Alagappa UniversityKaraikudi630001India Faculty of Computers and Information Mansoura UniversityMansoura35516Egypt Department of Project Management Ho Chi Minh City Open UniversityHo Chi Minh City7000000Vietnam

Diabetic retinopathy(DR)is a disease with an increasing prevalence and the major reason for blindness among working-age *** possibility of severe vision loss can be extensively reduced by timely diagnosis and *** automated screening for DR has been identified as an effective method for early DR detection,which can decrease the workload associated to manual grading as well as save diagnosis costs and *** studies have been carried out to develop automated detection and classification models for *** paper presents a new IoT and cloud-based deep learning for healthcare diagnosis of Diabetic Retinopathy(DR).The proposed model incorporates different processes namely data collection,preprocessing,segmentation,feature extraction and *** first,the IoT-based data collection process takes place where the patient wears a head mounted camera to capture the retinal fundus image and send to cloud ***,the contrast level of the input DR image gets increased in the preprocessing stage using Contrast Limited Adaptive Histogram Equalization(CLAHE)***,the preprocessed image is segmented using Adaptive Spatial Kernel distance measure-based Fuzzy C-Means clustering(ASKFCM)***,deep Convolution Neural Network(CNN)based Inception v4 model is applied as a feature extractor and the resulting feature vectors undergo classification in line with the Gaussian Naive Bayes(GNB)*** proposed model was tested using a benchmark DR MESSIDOR image dataset and the obtained results showcased superior performance of the proposed model over other such models compared in the study.

关键词： Deep learning classification GaussianNaive Bayes feature extraction diabetic retinopathy

Rigid body dynamics modeling, experimental characterization, and performance analysis of a howitzer

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Defence Technology（防务技术） 2016年第6期12卷 480-489页

作者： Nachiketa TIWARI Mukund PATIL Ravi shankar Abhishek SARASWAT Rituraj DWIVEDI Department of Mechanical Engineering Indian Institute of Technology Ordnance Factory Kanpur India

A large caliber howitzer is a complex and cumbersome assembly. Understanding its dynamics and performance attributes' sensitivity to changes in its design parameters can be a very time-consuming and expensive exercise, as such an effort requires highly sophisticated test rigs and platforms. However, the need of such an understanding is crucially important for system designers, users, and evaluators. Some of the key performance attributes of such a system are its vertical jump, forward motion, recoil displacement, and force transmitted to ground through tires and trail after the gun has been fired. In this work, we have developed a rigid body dynamics model for a representative howitzer system, and used relatively simple experimental procedures to estimate its principal design parameters. Such procedures can help in obviating the need of expensive experimental rigs, especially in early stages of the design cycle. These parameters were subsequently incorporated into our simulation model,which was then used to predict gun performance. Finally, we conducted several sensitivity studies to understand the influence of changes in various design parameters on system performance. Their results provide useful insights in our understanding of the functioning of the overall system.

关键词： Howitzer gun CAD modeling Dynamic simulation Recoil assembly parameters Sensitivity analysis

Adaptive Sub-Threshold Voltage Level Control for Voltage Deviate-Domino Circuits

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Intelligent Automation & Soft Computing 2023年第2期35卷 1767-1781页

作者： C.Arun Prasath C.Gowri shankar Department of Electronics and Communication Engineering Mahendra Engineering CollegeNamakkal637503India Department of Electrical and Electronics Engineering KSR College of EngineeringTiruchengode637215India

Leakage power and propagation delay are two signiﬁcant issues found in sub-micron technology-based Complementary Metal-Oxide-Semiconductor(CMOS)-based Very Large-Scale Integration(VLSI)circuit *** Channel Metal Oxide Semiconductor(PMOS)has been replaced by Negative Channel Metal Oxide Semiconductor(NMOS)in recent years,with low dimen-sion-switching changes in order to shape the mirror of voltage *** is used to reduce stacking leakage as well as total *** Logic Cir-cuit is a powerful and versatile digital programmer that gained popularity in recent *** this study regarding Adaptive Sub Threshold Voltage Level Control Pro-blem,the researchers intend to solve the contention issues,reduce power dissipa-tion,and increase the noise immunity by proposing Adaptive Sub Threshold Voltage Level Control(ASVLC)-based domino *** efﬁciency and effec-tiveness of the domino circuit are demonstrated through simulation *** suggested system makes use of high-speed broad fan-gate circuits,occupies mini-mum space,and consumes meagre amount of *** proposed circuit was validated in Cadence simulation tool at a supply voltage of 1V,frequency of 100 MHz,and an operating temperature of 27°C with 64 input OR *** per the simulation results,the suggested Domino Gate reduced the power dissipa-tion by 17.58 percent and improved the noise immunity by 1.21 times in compar-ison with standard domino logic circuits.

关键词： Domino logic power consumption ﬁgure of merit adaptive sub-threshold voltage level wide fan-in gates

Investigations on tribo-mechanical behaviour of Al-Si10-Mg/sugarcane bagasse ash/SiC hybrid composites

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China Foundry 2019年第4期16卷 277-284页

作者： shankar Subramanian Balaji Arunachalam Kawin Nallasivam Alokesh Pramanik Department of Mechatronics Engineering Kongu Engineering College Erode - 638060 TamilNadu India Department of Mechanical Engineering Kongu Engineering College Erode - 638060 TamilNadu India School of Civil and Mechanical Engineering Curtin University Bentley WA Australia

The effect of mechanical and tribological behaviour of aluminium alloy(Al-Si10-Mg) with sugarcane bagasse ash and silicon carbide reinforced metal matrix composites were investigated. Al-Si10-Mg alloy reinforced with 9 wt.% of treated sugarcane bagasse ash particles of size(< 75 μm) and 0 wt.%, 3 wt.%, 6 wt.% and 9 wt.% of silicon carbide particles of size(< 25 μm) were fabricated using the stir casting method. Morphological analysis was done using scanning electron microscopy to access the distribution of reinforcement particles in the matrix alloy. Tensile, hardness, and impact strengths were increased with an increase in weight fraction of SiC reinforcement particles in the aluminium alloy, while the ductility was decreased. Pin-on-disc dry sliding wear test was carried out with 10, 20 and 30 N loads with a sliding speed of 10 m·s-1 for a constant time period of 20 min to predict the wear behaviour of the developed composites. Worn surfaces of the wear-tested specimens and fracture morphology structure of the tensile-tested specimens were analysed. Results show that the composites reinforced with sugarcane bagasse ash and silicon carbide particles exhibit superior wear resistance.

关键词： aluminium alloy sugarcane bagasse ash silicon carbide mechanical properties wear fracture morphology

Microbial cells as biological factory for nanoparticle synthesis

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Frontiers of Materials Science 2021年第2期15卷 177-191页

作者： Bhabani shankar DAS Ankita DAS Abhisek MISHRA Manoranjan ARAKHA Centre for Biotechnology School of Pharmaceutical SciencesSiksha'O'Anusandhan(Deemed to be University)Bhubaneswar 751003OdishaIndia Symbiosis Institute of Health Sciences(SIHS) Symbiosis International(Deemed University)PuneMaharashtraIndia Biological E Limited ShameerpetHyderabadIndia

In present scenario,nanoscience and nanotechnology have drawn the attention of scientist and researchers as leading source of technology with a wide range of useful applications like pharmaceuticals,electronics,biotechnology,biomedicine,wastewater treatment,space technology,industries and medical sciences[1].The physico-chemical characteristics of nanomaterial could make them an ideal material for various *** this revolutionary effect,Norio Taniguchi,a famous scientist in 1974 coined the term‘nanotechnology’[2].

关键词： nanotechnology synthesis wastewater