Detoxication and Theranostic Aspects of Biosynthesised Zinc Oxide Nanoparticles for Drug Delivery

作     者：Krishnaswamy Kanagamani Pitchaipillai Muthukrishnan Ayyasami Kathiresan Karikalan Shankar Pandurengan Sakthivel Murugan Ilayaraja Krishnaswamy Kanagamani;Pitchaipillai Muthukrishnan;Ayyasami Kathiresan;Karikalan Shankar;Pandurengan Sakthivel;Murugan Ilayaraja

作者机构：Department of ChemistrySNS College of TechnologyCoimbatore641035India Department of ChemistryFaculty of EngineeringKarpagam Academy of Higher EducationCoimbatore641021India Department of PhysicsFaculty of EngineeringKarpagam Academy of Higher EducationCoimbatore641021India Department of ChemistryArumugam Pillai Seethai Ammal CollegeTirupattur630211India 

出 版 物：《Acta Metallurgica Sinica(English Letters)》 (金属学报（英文版）)

年 卷 期：2021年第34卷第5期

页      面：729-740页

核心收录：

学科分类：07[理学] 070205[理学-凝聚态物理] 08[工学] 0817[工学-化学工程与技术] 0806[工学-冶金工程] 0807[工学-动力工程及工程热物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 0802[工学-机械工程] 0703[理学-化学] 0811[工学-控制科学与工程] 0702[理学-物理学] 

基　　金：Karpagam Academy of Higher Education 

主　　题：Zinc oxide nanoparticles Anticancer activity Photocatalysis Congo red 

摘      要：Bioactive materials obtained from plant bio-resources offer immense attention for development and production of nanotechnology enabled products for biomedical *** the present study,Ficus hispida leaf extract(FHLE)was used as a stabilising agent for the environmentally benign synthesis of zinc oxide nanoparticles(ZnO-NPs)which were investigated for prospective versatile applications(anticancer and photocatalytic activities).The formation of ZnO-NPs was confirmed by UV–visible ***(hexagonal)form of the herb-assisted synthesised ZnO-NPs with particle size ranging from 20 to 200 nm was confirmed by transmission electron microscopy(TEM)*** vitro analysis was carried out against Dalton s lymphoma ascites(DLA)cell lines by trypan blue assay,the results revealed 96%inhibition at concentration of 200μg ml-1,and the photodegradation experiments carried out for degradation of Congo red revealed complete degradation of the dye after 70 min of exposure to UV light.