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A Hybrid Deep Learning-Based Unsupervised Anomaly Detection in High Dimensional Data

Computers, Materials & Continua 2022年第3期70卷 5363-5381页

作者： Amgad Muneer shakirah mohd taib Suliman Mohamed Fati Abdullateef O.Balogun Izzatdin Abdul Aziz Department of Computer and Information Sciences Universiti Teknologi PETRONASSeri Iskandar32160Malaysia Centre for Research in Data Science(CERDAS) Universiti Teknologi PETRONASSeri Iskandar32610PerakMalaysia Information Systems Department Prince Sultan UniversityRiyadh11586Saudi Arabia

Anomaly detection in high dimensional data is a critical research issue with serious implication in the real-world *** issues in this field still unsolved,so several modern anomaly detection methods struggle to maintain adequate accuracy due to the highly descriptive nature of big *** a phenomenon is referred to as the“curse of dimensionality”that affects traditional techniques in terms of both accuracy and ***,this research proposed a hybrid model based on Deep Autoencoder Neural Network(DANN)with five layers to reduce the difference between the input and *** proposed model was applied to a real-world gas turbine(GT)dataset that contains 87620 columns and 56 *** the experiment,two issues have been investigated and solved to enhance the *** first is the dataset class imbalance,which solved using SMOTE *** second issue is the poor performance,which can be solved using one of the optimization *** optimization algorithms have been investigated and tested,including stochastic gradient descent(SGD),RMSprop,Adam and ***,Adamax optimization algorithm showed the best results when employed to train *** experimental results show that our proposed model can detect the anomalies by efficiently reducing the high dimensionality of dataset with accuracy of 99.40%,F1-score of 0.9649,Area Under the Curve(AUC)rate of 0.9649,and a minimal loss function during the hybrid model training.

关键词： Anomaly detection outlier detection unsupervised learning autoencoder deep learning hybrid model

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Type 2 Diabetes Risk Prediction Using Deep Convolutional Neural Network Based-Bayesian Optimization

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Computers, Materials & Continua 2023年第5期75卷 3223-3238页

作者： Alawi Alqushaibi mohd Hilmi Hasan Said Jadid Abdulkadir Amgad Muneer Mohammed Gamal Qasem Al-Tashi shakirah mohd taib Hitham Alhussian Computer&Information Sciences Universiti Teknologi PETRONASSeri Iskandar32610PerakMalaysia Centre for Research in Data Science(CERDAS) Universiti Teknologi PETRONASSeri Iskandar32610PerakMalaysia Department of Imaging Physics University of Texas MD Anderson CancerHoustonTXUSA

Diabetes mellitus is a long-term condition characterized by *** could lead to plenty of *** to rising morbidity in recent years,the world’s diabetic patients will exceed 642 million by 2040,implying that one out of every ten persons will be *** is no doubt that this startling figure requires immediate attention from industry and academia to promote innovation and growth in diabetes risk prediction to save individuals’*** to its rapid development,deep learning(DL)was used to predict numerous ***,DLmethods still suffer from their limited prediction performance due to the hyperparameters selection and parameters ***,the selection of hyper-parameters is critical in improving classification *** study presents Convolutional Neural Network(CNN)that has achieved remarkable results in many medical domains where the Bayesian optimization algorithm(BOA)has been employed for hyperparameters selection and parameters *** issues have been investigated and solved during the experiment to enhance the *** first is the dataset class imbalance,which is solved using Synthetic Minority Oversampling Technique(SMOTE)*** second issue is the model’s poor performance,which has been solved using the Bayesian optimization *** findings indicate that the Bayesian based-CNN model superbases all the state-of-the-art models in the literature with an accuracy of 89.36%,F1-score of 0.88.6,andMatthews Correlation Coefficient(MCC)of 0.88.6.

关键词： Type 2 diabetes diabetes mellitus convolutional neural network Bayesian optimization SMOTE

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Diffusion tensor imaging pipeline measures of cerebral white matter integrity: An overview of recent advances and prospects

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World Journal of Clinical Cases 2022年第24期10卷 8450-8462页

作者： Amanina Ahmad Safri Che mohd Nasril Che mohd Nassir Ismail Nurul Iman Nur Hartini mohd taib Anusha Achuthan Muzaimi Mustapha Department of Neurosciences School of Medical SciencesUniversiti Sains MalaysiaHealth CampusKubang Kerian 16150KelantanMalaysia Department of Radiology School of Medical SciencesUniversiti Sains MalaysiaHealth CampusKubang Kerian 16150KelantanMalaysia School of Computer Sciences Universiti Sains Malaysia11800 USMPenangMalaysia Department of Neurosciences Hospital Universiti Sains MalaysiaKubang Kerian 16150KelantanMalaysia

Cerebral small vessel disease(CSVD)is a leading cause of age-related microvascular cognitive decline,resulting in significant morbidity and decreased quality of *** a progress on its key pathophysiological bases and general acceptance of key terms from neuroimaging findings as observed on the magnetic resonance imaging(MRI),key questions on CSVD remain *** relationships and reliable lesion studies,such as white matter tractography using diffusion-based MRI(dMRI)are necessary in order to improve the assessment of white matter architecture and connectivity in *** tensor imaging(DTI)and tractography is an application of dMRI that provides data that can be used to non-invasively appraise the brain white matter connections via fiber tracking and enable visualization of individual patient-specific white matter fiber tracts to reflect the extent of CSVD-associated white matter ***,due to a lack of standardization on various sets of software or image pipeline processing utilized in this technique that driven mostly from research setting,interpreting the findings remain contentious,especially to inform an improved diagnosis and/or prognosis of CSVD for routine clinical *** this minireview,we highlight the advances in DTI pipeline processing and the prospect of this DTI metrics as potential imaging biomarker for CSVD,even for subclinical CSVD in at-risk individuals.

关键词： Diffusion tensor imaging White matter Cerebral small vessel disease Pipeline processing Tractography

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Virtual reality research and development in NTU

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Virtual Reality & Intelligent Hardware 2020年第5期2卷 394-408页

作者： Lihui HUANG Siti Faatihah Binte mohd taib Ryan Aung BA Zhe An GOH Mengshan XU Nanyang Technological University 639798Singapore

In 1981,Nanyang Technological Institute was established in Singapore to train engineers and accountants to keep up with the fast-growing economy of the *** 1991,the institute was upgraded to Nanyang Technological University(NTU).NTU holds the rank for world's top young university for six consecutive years according to the Quacquarelli Symonds(QS)world university *** Reality(VR)research began in NTU in the late ***'s colleges,schools,institutes,and centers have contributed toward the excellence of VR *** article briefly describes the VR research directions and activities in NTU.

关键词： Virtual reality Research and development Nanyang Technological University Singapore

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Recovery of bird communities following the construction of a large-scale hydroelectric dam

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Ecological Processes 2021年第1期10卷 408-417页

作者： Affan Nasruddin-Roshidi Mohammad Saiful Mansor Nor Adibah Ismail Ehwan Ngadi mohd Izzat-Husna Shahril Mod Husin Farah Shafawati mohd-taib Rahmah Illias Shukor Md Nor Department of Biological Sciences and Biotechnology Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 BangiSelangorMalaysia Kolej GENIUS Insan Universiti Sains Islam MalaysiaBandar Baru Nilai71800 NilaiNegeri SembilanMalaysia TNB Research Sdn Bhd No.1Kawasan Institusi PenyelidikanJalan Ayer Itam43000 KajangSelangorMalaysia Department of Wildlife and National Parks(PERHILITAN) Km.10Jln Cheras56100 Kuala LumpurWilayah PersekutuanMalaysia.

Background:Habitat degradation is known to have a major impact on the composition of bird communities,yet how these communities recover following such disturbance is less *** study examined bird community changes from pre-logging to recovery over the course of habitat disturbance caused by the development of the Hulu Terengganu Hydroelectric Dam Project in Peninsular Malaysia,between 2007 and *** surveys were conducted using point count observations and mist netting in the dam area from the prelogging phase until the operation ***:It was observed that while bird species significantly declined after large-scale habitat clearance between the pre-logging and construction phases,they showed positive signs of recovery from the inundation to operation *** findings indicate that the bird community is still recovering,and the permanent loss of habitat required by most of the original species has not occurred,as evidenced by *** species composition differed across phases due to varying habitat *** turnover rate and immigration rate(recolonisation and newly recorded species)were higher between the construction and operation *** was also observed that insectivorous birds were more heavily affected than others by changes to the landscape,which highlights the versatility,survivability and tolerance of certain species to extreme disturbance and habitat ***:Although the operation phase showed an incremental change in bird species richness due to recolonisation and newly recorded species,this value remains far from that of the pre-logging *** predict that bird species recovery will continue to increase for some time before reaching a plateau among the newly created islands,reservoir and catchment area of the dam.

关键词： Dam construction Extinction Habitat recovery Recolonisation Turnover

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Molecular epidemiology of piliated pneumococcal isolates at a major tertiary hospital in the Klang Valley,Malaysia

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Asian Pacific Journal of Tropical Medicine 2023年第2期16卷 80-88页

作者： Nurul Diana Dzaraly mohd Nasir mohd Desa AbdulRahman Muthanna Siti Norbaya Masri Niazlin mohd taib Nurul Hana Zainal Baharin Nurshahira Sulaiman Nurul Asyikin Abdul Rahman Navindra Kumari Palanisamy Zarizal Suhaili Semiat Opeyemi Yusuff Nor Iza A.Rahman Tuan Suhaila Tuan Soh Fatimah Haslina Abdullah Department of Biomedical Sciences Faculty of Medicine and Health SciencesUniversiti Putra MalaysiaUPM SerdangSelangorMalaysia Department of Medical Microbiology Faculty of Medicine and Health SciencesUniversiti Putra MalaysiaUPM SerdangSelangorMalaysia School of Biology Faculty of Applied SciencesUniversiti Teknologi MARA Negeri SembilanKuala Pilah BranchKuala PilahNegeri SembilanMalaysia Department of Medical Microbiology and Parasitology Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusJalan HospitalSungai BulohSelangorMalaysia School of Animal Science Aquatic Science and EnvironmentFaculty of Bioresources and Food IndustryUniversiti Sultan Zainal AbidinBesut CampusBesutTerengganuMalaysia Faculty of Medicine Universiti Sultan Zainal AbidinJalan Sultan MahmudKuala TerengganuTerengganuMalaysia Department of Pathology Sungai Buloh HospitalJalan HospitalSungai BulohSelangorMalaysia Department of Pathology Sultanah Nur Zahirah HospitalJalan Sultan MahmudKuala TerengganuTerengganuMalaysia

Objective:To characterise a collection of pili-carrying and none pili-carrying pneumococcal isolates of clinical origin for serotypes,antibiotic resistance and ***:In total,42 clinical isolates were collected between October 2017 and December *** isolates were analysed for antimicrobial susceptibility,serotype distribution,detection of pneumococcal virulence and pilus *** sequence typing was performed only for piliated isolates,followed by phylogenetic ***:The common isolation sites among the pneumococcal isolates were tracheal aspirate(28.6%),blood(26.2%),and sputum(23.8%).Fifty percent isolates were resistant to erythromycin,tetracycline(50.0%)and trimethoprim-sulfamethoxazole(43.0%).The most frequent were serotypes 19F(28.6%),6A/B(23.8%)and 19A(14.3%).Piliated isolates were detected in a small proportion(33.3%);64.3%were ***320 was the prevalent sequence type among the piliated isolates and genetically related to the Pneumococcal Molecular Epidemiology Network clones Taiwan19F-14(CC271).In the phylogenetic analysis,some piliated isolates showed a close association having similar ST320,carrying serotype 19A and both pilus genes indicating their clonal ***:Pneumococcal lineages of piliated isolates have been globally disseminated and pili could have played a role in the spread of antibiotic resistant clones.

关键词： Pneumococci Pili Genotype Malaysia

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The evolution of pneumococcal vaccine on children in Malaysia:the efficacy and outcome

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Infectious Diseases Research 2021年第4期2卷 11-21页

作者： Semiat Opeyemi Yusuff Siti Norbaya Masri Nurul Diana Dzaraly Niazlin mohd taib mohd Nasir mohd Desa Department of Medical Microbiology and Parasitology Faculty of Medicine and Health SciencesUniversiti Putra MalaysiaSelangor43400 UPMSerdangMalaysia Department of Biomedical Sciences Faculty of Medicine and Health SciencesUniversiti Putra Malaysia43400 UPMSerdangSelangorMalaysia

With pathogenic bacterium,numerous studies have been conducted in developing new vaccines,and available pneumococcal vaccines have been implemented for the prevention of related ***,Streptococcus pneumoniae is known to have developed resistance to many of the proposed preventive *** a result,contemporary research,including our study,has reviewed how Streptococcus pneumoniae has become resistant to vaccines and to further determine how to prevent the negative effect of the non-vaccine serotype on vaccine serotype *** have been known as one of the bacteria that has highest preventive strength of vaccination provided to humans,where children’s immunity requires the vital of it,based on immunization schedule to boost their immune system against the diseases of high mortality and *** pneumococcal vaccines are derived from its strains called serotypes,and further research is being conducted to determine more potent vaccines from other pneumococcal virulence *** impose and implement the pneumococcal vaccine,the serotype distribution needs to be *** deal with this verification,clinical or carriage samples are required for the determination and differentiation of vaccine serotypes from non-vaccine *** Malaysia,the carriage rates are often limited to the clinical epidemiology of Streptococcus *** samples are more needed in tracking the vaccine efficacy for pre-and post-immunization to prevent and reduce pneumococcal diseases before they manifest into clinical ***,in this review article,we explore the mentioned highlights for sufficient discussion,discovery,and knowledgeable implementation of pneumococcal vaccine.

关键词： Streptococcus pneumoniae Serotype Vaccine Children Carriage Malaysia

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A Study of Vertical Wind Turbine for Application in Low Wind Speed Condition in UiTM Terengganu, Malaysia

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Journal of Power and Energy Engineering 2018年第8期6卷 38-48页

作者： Ermeey Abd Kadir mohd taib Miskon Nasran Abd Rashid Mat Yushafizee Yunus Faculty of Electrical Engineering Universiti Teknologi MARA Terengganu Branch Dungun Malaysia

This paper presented an investigation of an energy generation project by using a wind turbine in UiTM Terengganu, Malaysia. The significance of the project is to evaluate the proposed wind energy setup with the tropical environmental condition, especially in Malaysia. The wind turbine is built close to the seashore and facing the South China Sea. A relationship between wind speed with and the voltage level at the energy generator output terminal is analysed theoretically. Published wind speed data has been used in determining a suitable wind turbine system. Actual wind speed data is recorded starting from June 2017 until December 2017, and the data is compared with the published results. It has been found that the recorded data is in line with the published results. Moreover, it has been found that the mean wind speed collected at the proposed site is low, which is 2 m/s to 3.7 m/s. Furthermore, the wind turbine is actively producing energy for approximately 4 hours per day. A 300 W vertical axis wind turbine has been developed and tested, and it has been found that the efficiency of the energy generating system is less than 10%, which contributes for a significant amount per month.

关键词： Renewable Energy Wind Energy Potential

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Establishment of Human Neuroblastoma Cell-Line (SK-N-SH) as an In Vitro Model of Morphine Addiction

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Journal of Pharmacy and Pharmacology 2021年第3期9卷 115-121页

作者： Noor Azuin Suliman Noor Azlina Abu Bakar Mohamad Aris mohd Moklas Che Norma Mat taib Faculty of Medicine and Health Science Universiti Sultan Zainal Abidin(UniSZA)Kampus KotaJalan Sultan MahmudKuala Terengganu20400Malaysia Department of Biomedical Sciences Faculty of Medicine and Health SciencesUniversiti Putra Malaysia43400 UPM SerdangSelangorMalaysia

Morphine is a schedule II-controlled substance that used to allow the diminution of intra-operative, post-operative orchronic pain. However, its usage is limited due to addiction and overdose liabilities. Morphine was observed to cause tolerance,dependence and withdrawal in human. Justification: to date lack of scientific evidence of morphine addiction was carried out byusing specific single human neuroblastoma cell-line (SK-N-SH). Therefore, this study was performed to establish the morphineaddiction model in this cell line. The cells were exposed to morphine for 24 hrs before treatment with methadone, as ananti-withdrawal drug for subsequence 24 hours. The cytosolic fraction of the cell was used in different objectives including receptoraffinity, withdrawal properties, endocytic machinery, desensitisation or internalisation and cellular adaptation. The result shows thatmorphine and methadone bind to the μ-opioid receptor. The morphine-treated cells were observed to increase the expression ofaddiction markers, have a low rate of the endocytic machinery, cause desensitisation of receptor and reduce cellular *** changes by morphine were normalised by the treatment of methadone. As a whole, it is postulated that neuroblastoma cell line,SK-N-SH, can be used as an in-vitro model to demonstrate morphine addiction before animal and human testing.

关键词： Morphine addiction receptor affinity withdrawal properties endocytic machinery desensitisation internalisation cellular adaptation methadone.

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