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Review of Electrochemical Sensors and Biosensors Based on First-Row Transition Metals,Their Oxides,and Noble Metals Nanoparticles

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Journal of Analysis and Testing 2024年第2期8卷 143-159页

作者： Kulveer Singh Kuldeep kumar Maurya Manisha Malviya Department of Chemistry Indian Institute of Technology(Banaras Hindu University)Varanasi221005India

The use of electrochemical sensors for sensitive disease diagnosis and detecting various species with pharmacological,therapeutic,industrial,food-related,and environmental origins is now widely accepted.A catalytic or binding event resulting from the sensor’s electroactive component recognizing its analyte creates an electrical signal proportionate to the analyte concentration,which is then monitored by a *** development of morphologically distinct metal and metal oxide nanoparticles formed from first-row transition elements(Mn,Cr,Fe,Co,Ti,Ni,Cu,Zn)and noble metals(Pt,Au,Ag,Pd)is described in this *** effect of these metal nanoparticles has been studied using Tetracyanoquinodimethane(TCNQ),Ferrocene,and other organic compounds as electroactive species using carbon paste-modified *** sensors,mostly based on ferrocene,are exceedingly sensitive,selective,affordable,and for detecting numerous biomolecules like glucose,dopamine,NADH,ascorbic acid,and a few dyes and are simple to *** recent decades,charge transfer organic species-based chemosensors have become a prominent study *** paper outlines current developments in electrochemical biosensors based on transition metal nanoparticles,covering glucose,ascorbic acid,uric acid,and other inorganic and organic *** importance of transition metal and transition metal oxide nanoparticles as potential electrode modifiers for developing sensors is highlighted.A discussion of the present problem and possible solutions,and plausible future directions marks the review’s conclusion.

关键词： Electrochemical sensing Amperometry Cyclic voltammetry Square wave voltammetry Linear sweep voltammetry

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Dilation,discrimination and Uhlmann's theorem of link products of quantum channels

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Chinese Physics B 2024年第3期33卷 201-206页

作者：雷强操刘桁 Asutosh kumar 武俊德 School of Mathematical Sciences Harbin Institute of TechnologyHarbin 150001China Department of Physics Gaya CollegeMagadh UniversityRampurGaya 823001India School of Mathematical Sciences Zhejiang UniversityHangzhou 310027China

We establish the Stinespring dilation theorem of the link product of quantum channels in two different ways,discuss the discrimination of quantum channels,and show that the distinguishability can be improved by self-linking each quantum channel n times as n *** also find that the maximum value of Uhlmann's theorem can be achieved for diagonal channels.

关键词： quantum channels link products Stinespring dilation theorem Uhlmann's theorem

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Implication of machine learning techniques to forecast the electricity price and carbon emission:Evidence from a hot region

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Geoscience Frontiers 2024年第3期15卷 259-271页

作者： Suleman Sarwar Ghazala Aziz Aviral kumar Tiwari Department of Finance and Economics College of BusinessUniversity of JeddahJeddahSaudi Arabia Department of Business Administration College of Administrative and Financial SciencesSaudi Electronic UniversityJeddahSaudi Arabia Indian Institute of Management BodhgayaIndia

The current study examines the significant determinants of electricity consumption and identifies an appropriate model to forecast the electricity price *** main contribution is focused on eastern region of Saudi Arabia,a relatively hottest geographical area full of energy resources but with different electricity consumption *** relative irrelevance of temperature as predicting factor of electricity consumption is quite surprising and contradicts the previous *** the eastern region,electricity price has negative association with electricity *** comparing traditional and machine learning,it is found that machine learning techniques offer better *** the machine learning techniques,the support vector machine has the lowest errors in forecasting the electricity ***,the support vector machine approach is used to forecast the trend of carbon emissions caused by electricity *** findings have policy implications and offer valuable suggestions to policymakers while addressing the determinants of electricity consumption and forecasting electricity prices.

关键词： Electricity consumption Carbon emission Artificial neural network Support vector machine Saudi Arabia

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Drug resistance mechanisms in cancers:Execution of prosurvival strategies

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Journal of Biomedical Research 2024年第2期38卷 95-121页

作者： Pavan kumar Dhanyamraju Fels Cancer Institute of Personalized Medicine Lewis-Katz School of MedicineTemple UniversityPhiladelphiaPA 19140USA

One of the quintessential challenges in cancer treatment is drug *** mechanisms of drug resistance have been described to date,and new modes of drug resistance continue to be *** phenomenon of cancer drug resistance is now widespread,with approximately 90% of cancer-related deaths associated with drug *** significant advances in the drug discovery process,the emergence of innate and acquired mechanisms of drug resistance has impeded the progress in cancer ***,understanding the mechanisms of drug resistance and the various pathways involved is integral to treatment *** the present review,I discuss the different mechanisms of drug resistance in cancer cells,including DNA damage repair,epithelial to mesenchymal transition,inhibition of cell death,alteration of drug targets,inactivation of drugs,deregulation of cellular energetics,immune evasion,tumor-promoting inflammation,genome instability,and other contributing epigenetic ***,I highlight available treatment options and conclude with future directions.

关键词： cancer drug resistance mechanisms microRNAs treatment strategies

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Protected simultaneous quantum remote state preparation scheme by weak and reversal measurements in noisy environments

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Chinese Physics B 2024年第2期33卷 169-177页

作者： Mandal Manoj kumar Choudhury Binayak S. Samanta Soumen Department of Mathematics Indian Institute of Engineering Science and TechnologyShibpur B.GardenHowrah 711103West BengalIndia

We discuss a quantum remote state preparation protocol by which two parties, Alice and Candy, prepare a single-qubit and a two-qubit state, respectively, at the site of the receiver Bob. The single-qubit state is known to Alice while the two-qubit state which is a non-maximally entangled Bell state is known to Candy. The three parties are connected through a single entangled state which acts as a quantum channel. We first describe the protocol in the ideal case when the entangled channel under use is in a pure state. After that, we consider the effect of amplitude damping(AD) noise on the quantum channel and describe the protocol executed through the noisy channel. The decrement of the fidelity is shown to occur with the increment in the noise parameter. This is shown by numerical computation in specific examples of the states to be created. Finally, we show that it is possible to maintain the label of fidelity to some extent and hence to decrease the effect of noise by the application of weak and reversal measurements. We also present a scheme for the generation of the five-qubit entangled resource which we require as a quantum channel. The generation scheme is run on the IBMQ platform.

关键词： multi-qubit entangled channel quantum remote state preparation noisy environments weak and reversal measurements

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Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates

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Genes & Diseases 2024年第1期11卷 34-37页

作者： Budhadev Baral Dharmendra Kashyap Nidhi Varshney Tarun Prakash Verma Ajay kumar Jain Debi Chatterji Vinod kumar Amit Mishra Awanish kumar Hem Chandra Jha Infection Bioengineering Group Department of Biosciences and Biomedical EngineeringIndian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Choithram Hospital and Research Center IndoreMadhya Pradesh452014India Department of Metallurgy Engineering and Materials Science Indian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Department of Bioscience&Bioengineering Indian Institute of Technology JodhpurNH 65 Nagaur RoadJodhpur DistrictKarwarRajasthan 342037India Department of Biotechnology National Institute of Technology RaipurGE RoadRaipurChhattisgarh 492010India

Persistent gastritis induced by Helicobacter pylori(***)is the strongest known risk factor for gastric cancer(GC).*** is prevalent in about 50%world's population,while it causes cancer in less than 2%of exposed individuals.1 Our studies found that *** infection can induce oncogenic properties in AGS cells by deregulating multiple factors associated with the cell cycle,apoptosis,and other important events associated with cancer progression.

关键词： H.pylori pylori Helicobacter

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Effect of random movement and cooperative hunting in the prey-predator system:A dynamical approach

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International Journal of Biomathematics 2024年第3期17卷 211-240页

作者： Shivam Teekam Singh Mukesh kumar Department of Mathematics Graphic Era Deemed to be University 566/6 Bell RoadSociety AreaClenent Town DehradunUttarakhand 248002India Department of Computer Science and Engineering Graphic Era Deemed to be University 566/6 Bell RoadSociety AreaClement Town DehradunUttarakhand 248002India

Self-diffusion prerequisite is obtained as the spreading approach of biological *** hunting is a common behavior in predator populations that promotes predation and the coexistence of the prey-predator *** the other side,the Allee effect among prey may cause the system to become *** this paper,a difusive prey predator system with cooperative hunting and the weak Allee effect in prey populations is *** linear stability and Hopf-bifurcation analysis had been used to examine the system's *** the spatial stability of the system,the conditions for Turing instability have been *** multiple-scale analysis has been used to derive the amplitude equations of the *** stability analysis of these amplitude equations leads to the formation of Turing ***,numerical simulations are used to analyze spatial patterns forming in 1-D and *** studies indicate that the model can generate a complex pattern structure and that self-diffusion has a drastic impacton species distribution.

关键词： Prey predator system hunting cooperation Allee effect Hopf-bifurcation diffusive instability amplitudeequation

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Hybrid Approach for Cost Efficient Application Placement in Fog-Cloud Computing Environments

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Computers, Materials & Continua 2024年第6期79卷 4127-4148页

作者： Abdulelah Alwabel Chinmaya kumar Swain Department of Computer Sciences College of Computer Engineering and SciencesPrince Sattam bin Abdulaziz UniversityAl-Kharj11942Saudi Arabia Department of Computer Science and Engineering Institute of Management and Information TechnologyCuttackBPUTOdishaIndia

Fog computing has recently developed as a new paradigm with the aim of addressing time-sensitive applications better than with cloud computing by placing and processing tasks in close proximity to the data ***,the majority of the fog nodes in this environment are geographically scattered with resources that are limited in terms of capabilities compared to cloud nodes,thus making the application placement problem more complex than that in cloud *** approach for cost-efficient application placement in fog-cloud computing environments that combines the benefits of both fog and cloud computing to optimize the placement of applications and services while minimizing *** approach is particularly relevant in scenarios where latency,resource constraints,and cost considerations are crucial factors for the deployment of *** this study,we propose a hybrid approach that combines a genetic algorithm(GA)with the Flamingo Search Algorithm(FSA)to place application modules while minimizing *** consider four cost-types for application deployment:Computation,communication,energy consumption,and *** proposed hybrid approach is called GA-FSA and is designed to place the application modules considering the deadline of the application and deploy them appropriately to fog or cloud nodes to curtail the overall cost of the *** extensive simulation is conducted to assess the performance of the proposed approach compared to other state-of-the-art *** results demonstrate that GA-FSA approach is superior to the other approaches with respect to task guarantee ratio(TGR)and total cost.

关键词： Placement mechanism application module placement fog computing cloud computing genetic algorithm flamingo search algorithm

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Wharton’s jelly mesenchymal stem cells: Future regenerative medicine for clinical applications in mitigation of radiation injury

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World Journal of Stem Cells 2024年第7期16卷 742-759页

作者： Prashasti Sharma Dharmendra kumar Maurya Life Sciences Homi Bhabha National InstituteMumbai 400094MaharashtraIndia Radiation Biology&Health Sciences Division Bhabha Atomic Research CentreMumbai 400085MaharashtraIndia

Wharton’s jelly mesenchymal stem cells(WJ-MSCs)are gaining significant attention in regenerative medicine for their potential to treat degenerative diseases and mitigate radiation ***-MSCs are more naïve and have a better safety profile,making them suitable for both autologous and allogeneic *** review highlights the regenerative potential of WJ-MSCs and their clinical applications in mitigating various types of radiation *** this review,we will also describe why WJ-MSCs will become one of the most probable stem cells for future regenerative medicine along with a balanced view on their strengths and ***,the most updated literature related to both preclinical and clinical usage of WJ-MSCs for their potential application in the regeneration of tissues and organs will also be compiled.

关键词： Stem cells Wharton’s jelly mesenchymal stem cells Radiotherapy Xerostomia Lung fibrosis

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Hydro-uvarovite from Mantle Peridotites of Naga Hills Ophiolite: A Mineral Tracer for Neo-Tethyan Mantle Wedge Metasomatism

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Acta Geologica Sinica(English Edition) 2024年第4期98卷 867-877页

作者： Anisha VERENCAR Abhishek SAHA Nilanjana SORCAR Sohini GANGULY Pankaj kumar Atul kumar SINGH CSIR-National Institute of Oceanography Dona PaulaGoa 403004India School of Earth Ocean and Atmospheric SciencesGoa UniversityTaleigao PlateauGoa 403206India National Centre for Earth Science Studies ThiruvananthapuramKeralaIndia Inter University Accelerator Centre(IUAC) New Delhi 110067India North-Eastern Hill University ShillongMeghalaya 793022India

Hydrous Cr-bearing uvarovite garnets are rare in natural occurrences and belong to the ugrandite series and exist in binary solid solutions with grossular and andradite garnets. Here, we report the occurrence of hydrous uvarovite garnet having Cr_(2)O_(3) upto 19.66 wt% and CaO of 32.12–35.14 wt% in the serpentinized mantle peridotites of Naga Hills Ophiolite(NHO), India. They occur in association with low-Cr diopsides. They are enriched in LILE(Ba, Sr), LREEs, with fractionating LREE-MREE [avg.(La/Sm)_(N) = 2.16] with flat MREE/HREE patterns [avg.(Sm/Yb)_(N) = 0.95]. Raman spectra indicate the presence of hydroxyl(OH^(–)) peaks from 3500 to 3700 cm^(-1). Relative abundances in fluid mobile elements and their close association with clinopyroxenes are suggestive of the formation of uvarovite garnets through low temperature metasomatic alteration of low-Cr diopsides by hydrothermal slab fluids. The high LREE concentration and absence of Eu anomaly in the garnet further attest to alkaline nature of the transporting slab dehydrated fluid rather the involvement of low-p H solution. The chemical characteristics of the hydroxyl bearing uvarovite hosted by the mantle peridotite of NHO deviate from the classical features of uvarovite garnet, and their origin is attributed to the fluid-induced metasomatism of the sub arc mantle wedge in a suprasubduction zone regime.

关键词： uvarovite hydroxyl metasomatic alteration low-Cr diopsides serpentinization mantle peridotite

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