Wharton’s jelly mesenchymal stem cells: Future regenerative medicine for clinical applications in mitigation of radiation injury

作     者：Prashasti Sharma Dharmendra Kumar Maurya 

作者机构：Life SciencesHomi Bhabha National InstituteMumbai 400094MaharashtraIndia Radiation Biology&Health Sciences DivisionBhabha Atomic Research CentreMumbai 400085MaharashtraIndia 

出 版 物：《World Journal of Stem Cells》 (世界干细胞杂志（英文版）（电子版）)

年 卷 期：2024年第16卷第7期

页      面：742-759页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 0836[工学-生物工程] 

主　　题：Stem cells Wharton’s jelly mesenchymal stem cells Radiotherapy Xerostomia Lung fibrosis 

摘      要：Wharton’s jelly mesenchymal stem cells(WJ-MSCs)are gaining significant attention in regenerative medicine for their potential to treat degenerative diseases and mitigate radiation ***-MSCs are more naïve and have a better safety profile,making them suitable for both autologous and allogeneic *** review highlights the regenerative potential of WJ-MSCs and their clinical applications in mitigating various types of radiation *** this review,we will also describe why WJ-MSCs will become one of the most probable stem cells for future regenerative medicine along with a balanced view on their strengths and ***,the most updated literature related to both preclinical and clinical usage of WJ-MSCs for their potential application in the regeneration of tissues and organs will also be compiled.