Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates

作     者：Budhadev Baral Dharmendra Kashyap Nidhi Varshney Tarun Prakash Verma Ajay Kumar Jain Debi Chatterji Vinod Kumar Amit Mishra Awanish Kumar Hem Chandra Jha Budhadev Baral;Dharmendra Kashyap;Nidhi Varshney;Tarun Prakash Verma;Ajay Kumar Jain;Debi Chatterji;Vinod Kumar;Amit Mishra;Awanish Kumar;Hem Chandra Jha

作者机构：Infection Bioengineering GroupDepartment of Biosciences and Biomedical EngineeringIndian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Choithram Hospital and Research CenterIndoreMadhya Pradesh452014India Department of Metallurgy Engineering and Materials ScienceIndian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Department of Bioscience&BioengineeringIndian Institute of Technology JodhpurNH 65 Nagaur RoadJodhpur DistrictKarwarRajasthan 342037India Department of BiotechnologyNational Institute of Technology RaipurGE RoadRaipurChhattisgarh 492010India 

出 版 物：《Genes & Diseases》 (基因与疾病（英文）)

年 卷 期：2024年第11卷第1期

页      面：34-37页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：funded by SERB India(No.EMR/2017/001637) 

主　　题：H.pylori pylori Helicobacter 

摘      要：Persistent gastritis induced by Helicobacter pylori(***)is the strongest known risk factor for gastric cancer(GC).*** is prevalent in about 50%world s population,while it causes cancer in less than 2%of exposed individuals.1 Our studies found that *** infection can induce oncogenic properties in AGS cells by deregulating multiple factors associated with the cell cycle,apoptosis,and other important events associated with cancer progression.