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Effects of Supplemen.al Glutamin. an. Lysin. on.Growth Performan.e of Broiler Chicken.

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Open.Journ.l of An.mal Scien.es 2024年第2期14卷 101-122页

作者： Ali F. Alsogair n.if M. Alhawiti samuel n. n.hashon n.tion.l Cen.er for Wildlife Riyadh KSA Californ.a An.mal Health an. Food Safety Laboratory University of California Davis Davis USA Departmen. of Agricultural an. En.iron.en.al Scien.es College of Agriculture Tennessee State University Nashville Tennessee USA

The optimum levels of Lysin. an. Glutamin. n.eded for growth performan.e an. main.en.n.e of the chicken.broilers were evaluated in.a ran.omized 3 × 4 factorial arran.emen. of dietary treatmen.s. The battery cages measured 99 × 66 × 25 cm that can.be sufficien. for 5 birds. Day old Chicken.broilers totalin. 180 were assign.d to dietary treatmen.s comprisin. of 3 con.en.ration. of Lysin. (0.85, 1.14, an. 1.42) each in.combin.tion.with 4 con.en.ration. of Glutamin. (0, 1, 2, an. 3). Each dietary treatmen. was replicated 3 times an. each replication.had 5 birds. The birds were given.feed an. water ad libitum with a 23-hour light regimen.for a period of 4 weeks. Then. the experimen.al birds were evaluated for body weight gain. feed con.umption. an. feed con.ersion.in.order to determin. their optimum requiremen. for dietary Lysin. an. Glutamin.. Based on.the fin.in.s of this study, the highest performan.e was observed in.birds fed the diet supplemen.ed with 1.42 lysin. an. 1% glutamin., but the highest improvemen. in.feed con.ersion.was observed in.diet con.ain.1.14 an. 1.42 with 1% an. 3% glutamin., respectively. Birds fed 1.42 lysin. an. 1% glutamin. had the highest total body weight gain.an. feed con.umption. The lysin. requiremen.s in.the diet for Chicken.are between.1.14 an. 1.42 with glutamin. level of 1%.

关键词： Broiler Chicken. Lysin. Glutamin. Amin. Acid Dietary Protein Essen.ials AAs n.n.Essen.ial Amin. Acids

Ethical decision.makin. in.older drivers durin. critical drivin. situation.: An.on.in. experimen.

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Journal of Intelligent and Connected Vehicles

Journ.l of In.elligen. an. Con.ected Vehicles 2024年第1期7卷 30-37页

作者： Aman.eep Sin.h Sarah Yahoodik Yovela Murzello samuel Petkac Yusuke Yaman. Siby samuel Departmen. of Systems Design.En.in.erin. University of WaterlooWaterloo N2L 3G1Canada Departmen. of Psychology Old Dominion UniversityNorfolk 23529USA

The presen. study examin.d the impact of agin. on.ethical decision.makin. in.simulated critical drivin. scen.rios.204 participan.s from n.rth America,grouped in.o two age groups(18–30 years an. 65 years an. above),were asked to decide whether their simulated automated vehicle should stay in.or chan.e from the curren. lan. in.scen.rios mimickin. the Trolley *** participan. viewed a video clip ren.ered by the drivin. simulator at Old Domin.on.Un.versity an. pressed the space-bar if they decided to in.erven. in.the con.rol of the simulated automated vehicle in.an.on.in. *** hierarchical models were used to an.lyze participan.s’respon.es,respon.e time,an. acceptability of utilitarian.ethical *** results showed sign.fican. pedestrian.placemen.,age,an. time-to-collision.TTC)effects on.participan.s’ethical *** pedestrian. were in.the right lan.,participan.s were more likely to switch lan.s,in.icatin. a utilitarian.approach prioritizin. pedestrian.*** participan.s were more likely to switch lan.s in.gen.ral compared to older *** results imply that older drivers can.main.ain.their ability to respon. to ethically fraught scen.rios with their ten.en.y to switch lan.s more frequen.ly than.youn.er coun.erparts,even.when.the tasks in.eractin. with an.automated drivin. *** curren. fin.in.s may in.orm the developmen. of decision.algorithms for in.elligen. an. con.ected vehicles by con.iderin. poten.ial ethical dilemmas faced by human.drivers across differen. age groups.

关键词： ethical decision.makin. age-differen.es utilitarian.sm moral dilemmas driver behavior simulated drivin. bayesian.hierarchical model

An.electropen.trography waveform library for the probin. an. in.estion.behaviors of Culex tarsalis on.human.han.s

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In.ect Scien.e 2024年第4期31卷 1165-1186页

作者： An.stasia M.W.Cooper samuel B.Jameson.Victoria Picken. Cameron.Osborn. Elain. A.Backus Kristopher Silver Dan. n.Mitzel Departmen. of En.omology Kansas State UniversityManhattanKansasUSA Departmen. of Tropical Medicin. Tulane University School of Public Health and Tropical MedicineNew OrleansLos AngelesUSA USDA Agricultural Research Service San Joaquin Valley Agricultural Sciences CenterParlierCaliforniaUSA n.tion.l Bio an. Agro-Defen.e Facility USDA Agricultural Research ServiceManhattanKansasUSA

Culex tarsalis Coquillett(Diptera:Culicidae)mosquitoes are capable of vectorin. n.merous pathogen. affectin. public an. an.mal ***,the probin. behaviors of mosquitoes are poorly un.erstood because they occur in.opaque ***(EPG)has the poten.ial to elucidate these behaviors by recordin. the electrical sign.ls gen.rated durin. *** used an.AC–DC EPG with variable in.ut resistors(Ri levels)to con.truct a waveform library for *** feedin. on.human.*** even.s associated with mosquito probin. were used to characterize waveforms at four Ri levels an. with two electrical curren. *** optimal settin.s for EPG recordin.s of *** probin. on.human.han.s was an.Ri level of 10^(7)Ohms usin. an.applied sign.l of 150 millivolts altern.tin. *** for *** in.luded those previously observed an. associated with probin. behaviors in.Aedes aegypti L.(Diptera:Culicidae):waveform families J(surface salivation.,K(stylet pen.tration.through the skin.,L(types 1 an. 2,search for a blood vessel/in.estion.site),M(types 1 an. 2,in.estion.,n.type 1,an.un.n.wn.behavior which may be a restin. an. digestion.phase),an. W(withdrawal).However,we also observed variation. in.the waveforms n.t described in.***,which we n.med types L3,M3,M4,an. *** in.estigation.en.an.es our un.erstan.in. of mosquito probin. *** also provides a n.w tool for the automated calculation.of peak *** work will facilitate future pathogen.acquisition.an. tran.mission.studies an. help iden.ify n.w pest an. disease man.gemen. targets.

关键词： AC-DC blood feeders electrical pen.tration.graph EPG human.han.s mosquitoes waveform library

Hepatic an.ioten.in.con.ertin. en.yme 2 expression.in.metabolic dysfun.tion.associated steatotic liver disease an. in.patien.s with fatal COVID-19

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World Journ.l of Gastroen.erology 2024年第31期30卷 3705-3716页

作者： An.us K Jacobs Steven.D Morley Kay samuel Katie Morgan.Lyn.sey Boswell Timothy J Ken.all David A Dorward Jon.than.A Fallowfield Peter C Hayes John.n.Plevris Hepatology Laboratory University of EdinburghEdinburgh EH164SBUnited Kingdom Scottish n.tion.l Blood Tran.fusion.Service Jack Copland CentreEdinburgh EH144BEUnited Kingdom In.titute for Regen.ration.an. Repair University of EdinburghEdinburgh EH164UUUnited Kingdom Edin.urgh Pathology University of EdinburghEdinburgh EH164SBUnited Kingdom

BACKGROUn. Metabolic dysfun.tion.associated steatotic liver disease(MASLD),characterised by hepatic lipid accumulation.causes in.lammation.an. oxidative stress accompan.ed by cell damage an. *** in.ury(LI)is also frequen.ly reported in.patien.s hospitalised with coron.virus disease 2019(COVID-19),while preexistin. MASLD in.reases the risk of LI an. the developmen. of COVID-19-associated *** of in.ury at the cellular level remain.un.lear,but it may be sign.fican. that severe acute respiratory syn.rome coron.virus 2(SARS-CoV-2)which causes COVID-19,uses an.ioten.in.con.ertin. expression.en.yme 2(ACE2),a key regulator of the‘an.i-in.lammatory’arm of the ren.n.an.ioten.in.system,for viral attachmen. an. host cell *** To determin. if hepatic ACE2 levels are altered durin. progression.of MASLD an. in.patien.s who died with severe *** ACE2 protein.levels an. localisation.an. histological fibrosis an. lipid droplet accumulation.as markers of MASLD were determin.d in.formalin.fixed liver tissue section. across the MASLD pathological spectrum(isolated hepatocellular steatosis,metabolic dysfun.tion.associated steatohepatitis(MASH)+/-fibrosis,en.-stage cirrhosis)an. in.post-mortem tissues from patien.s who had died with severe COVID-19,usin. ACE2 immun.histochemistry an. haematoxylin.an. eosin.an. picrosirius red stain.n. of total collagen.an. lipid droplet areas,followed by quan.ification.usin. machin. learn.n.-based image pixel *** ACE2 stain.n. is primarily in.racellular an. con.en.rated in.the cytoplasm of cen.rilobular hepatocytes an. apical membran.s of bile duct ***,ACE2 protein.levels are elevated in.n.n.fibrotic MASH compared to healthy con.rols but n.t in.the progression.to MASH with fibrosis an. in.***2 protein.levels an. histological fibrosis are n.t associated,but ACE2 an. liver lipid droplet con.en. are sign.fican.ly correlated across the MASLD *** A

关键词： Metabolic dysfun.tion.associated steatotic liver disease An.ioten.in.con.ertin. en.yme 2 Immun.histochemistry COVID-19 COVID-19-associated cholan.iopathy

Academic productivity correlates with in.ustry earn.n.s in.foot an. an.le fellowship programs in.the Un.ted States:A retrospective an.lysis

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World Journ.l of Orthopedics 2024年第2期15卷 129-138页

作者： Albert T An.stasio An.hon. n.Bauman. Kemplan. C Walley Kyle J Hitchman.Con.r O’n.ill Jon.than.Kaplan.samuel B Adams Departmen. of Orthopedic Surgery Duke University HospitalDurhamNC 27710United States College of Medicin. Northeast Ohio Medical UniversityRootstownOH 44272United States Departmen. of Orthopedic Surgery University of MichiganAnn ArborMI 48109United States School of Osteopathic Medicin. Campbell UniversityLillingtonNC 27546United States

BACKGROUn. The study in.estigates the con.ection.between.academic productivity an. in.ustry earn.n.s in.foot an. an.le orthopedic surgery *** metrics like the H-in.ex an. Open.Paymen.s Database(OPD)data,it addresses a gap in.un.erstan.in. the relation.hip between.scholarly achievemen.s an. fin.n.ial outcomes,providin. a basis for further exploration.in.this specialized medical *** To elucidate the tren.s between.academic productivity an. in.ustry earn.n.s across foot an. an.le orthopedic surgery fellowship programs in.the Un.ted *** This study is a retrospective an.lysis of the relation.hip between.academic productivity an. in.ustry earn.n.s of foot an. an.le orthopedic surgery fellowships at an.in.ividual faculty an. fellowship *** productivity was defin.d via H-in.ex an. recorded from the Scopus *** earn.n.s were recorded from the *** Forty-eight foot an. an.le orthopedic surgery fellowships(100%of fellowships)in.the Un.ted States with a combin.d total of 165 physician.(95.9%of physician.)were *** in.ividual physician.n.165)total life-time earn.n.s reported on.the OPD website was Un.ted States Dollar(USD)451430.30±1851084.89(ran.e:USD 25.16-21269249.85;median.USD 27839.80).Mean.physician.n.165)H-in.ex as reported on.Scopus is 14.24±12.39(ran.e:0-63;median.11).There was a sign.fican. but weak correlation.between.in.ividual physician.H-in.ex an. in.ividual physician.total life-time earn.n.s(Pn.s rho=0.334)an. a sign.fican. an. moderate positive correlation.between.combin.d fellowship H-in.ex an. total life-time earn.n.s per fellowship(P=0.004,Spearman.s rho=0.409).COn.LUSIOn.There is a sign.fican. an. positive correlation.between.academic productivity an. in.ustry earn.n.s at foot an. an.le orthopedic surgery fellowships in.the Un.ted *** observation.is true on.an.in.ividual physician.level as well as on.a fellowship level.

关键词： Sun.hin. act Foot an. an.le Orthopedic surgery Orthopedic fellowship In.ustry earn.n.s

Frequen.y of the C677T Polymorphism of MTHFR, G20210A of Prothrombin.an. R506Q of Factor V Leiden.in.Type 2 Diabetics in.Abidjan

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Open.Journ.l of Gen.tics 2024年第1期14卷 13-25页

作者： n.Guessan.Blao Rebecca Yapo Vin.en. Yayo-ayé Mireille Adjambri Eusèbe Kon.-Kon. Fatoumata Sawadogo Dun. Hematology an. Gen.ral Biology Un.t Faculty of Pharmaceutical and Biological Sciences Department of Biological Sciences Felix Houphouet-Boigny University Abidjan Ivory Coast Laboratory of Biology an. Medical Research National Institute of Public Health (INSP) Abidjan Ivory Coast Molecular Biology Un.t Center for Diagnosis and Research on AIDS and Other Infectious Diseases (CeDReS) Treichville University Hospital (CHU) Abidjan Ivory Coast

In.Africa, the prevalen.e of diabetes is escalatin. an. remain. a con.ern.due to the n.merous complication. it causes. Vascular damage associated with diabetes leads to a prothrombotic state observed in.diabetic in.ividuals. Diabetes is a complex an. multifactorial disease in.olvin. gen.tic compon.n.s. With the aim of preven.in. complication. an. con.ributin. to an.efficien. man.gemen. of diabetes, we in.estigated gen.s likely to lead to a risk of thrombosis, in.particular the C677T of MTHFR, G20210A of prothrombin. an. R506Q of factor V Leiden.in.type 2 diabetics in.Abidjan.receivin. ambulatory care. A descriptive cross-section.l study was carried out on.con.en.in. type 2 diabetic patien.s. Mutation.detection.was carried out usin. the PCR-RFLP method employin. restriction.en.ymes. Hemostasis tests (fibrin.gen. D-dimers, fibrin.mon.mers, an. von.Willebran. factor) were performed usin. citrate tubes on.the Stage? Star Max automated system. Plasmin.gen.activator in.ibitor was assayed by ELISA method, an. biochemical parameters were determin.d usin. the COBAS C311. The study population.con.isted of 45 diabetic patien.s, 51.1% of whom presen.ed vascular complication., main.y n.uropathy. Disturban.es in.hemostasis parameters were observed, with 15.5% of patien.s showin. an.in.rease in.fibrin.mon.mers. Mutation.an.lysis revealed an.absen.e of factor V mutation.(factor V Leiden. an. of G20210A mutation.of the prothrombin.gen.. However, 15.6% of subjects had a heterozygous C677T mutation.of MTHFR, with 57% of them bein. an.mic. The exploration.of biological an. gen.tic factors associated with thrombotic risk is of sign.fican. in.erest in.the optimal man.gemen. of African.type 2 diabetics.

关键词： Type 2 Diabetes C677T of MTHFR G20210A Factor V Leiden Thrombosis

Volcan.c Risk Perception.an. Copin. Strategies from Moun.s Cameroon.an. n.iragon.o Eruption., Cen.ral Africa: A Comparative An.lysis

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Journ.l of Geoscien.e an. En.iron.en. Protection 2024年第6期12卷 161-189页

作者： Mabel n. Wan.im In.ocen. Bradriyo Ason. F. Zisuh Louis M. Balgawa Mero Yan.ah Katcho Karume n.e-Fon.Peter Bih Amban.n.hin. L. Wayih Emman.el V. Yen.hu samuel n. ay.nghe Un.t of Disaster Risk Man.gemen. Department of Environmental Science University of Buea Buea Cameroon Observatoire Volcan.logique de Goma (OVG) Goma Democratic Republic of the Congo In.titute of Geological an. Min.n. Research (IRGM) Yaounde Cameroon Faculty of Health Scien.es University of Buea Buea Cameroon Faculty of Social an. Man.gemen. Scien.es University of Buea Buea Cameroon

Approximately 2,000,000 people are exposed to volcan.c risks in.commun.ties situated at the flan.s of Moun.s Cameroon.(MC) an. n.iragon.o (Mn. volcan.es in.Cen.ral Africa. This study therefore sought to in.estigate risk perception.from four previous eruption. of MC, n.mely the 1959, 1982, 1999, an. 2000 eruption.;an. two previous eruption. of Mn. 1977 an. 2002. The study was in.tiated with co-design.workshops held with major stakeholders in.the cities of Buea an. Goma at the flan.s of MC an. Mn. respectively, in.2017, to develop the research objectives for the study. A n.n.ran.om question.aire survey was later con.ucted within.14 an. 15 commun.ties in.Buea an. Goma respectively, on.the effects, perceived risks, an. copin. strategies for the chosen.eruption.. Three age groups (18 - 30, 31 - 45 an. >45 years) an. gen.er (male an. female) were con.idered. The population.at the flan.s of both volcan.es cited scien.ific an. in.igen.us factors to be respon.ible for eruption. from these volcan.es. At MC an. Mn. ≥45% of the sampled participan.s (with a higher female population. perceived that the sampled eruption. posed a very high risk to the population. In.terms of the effects, the age group of 18 - 30 was the least kn.wledgeable. In.terms of direct effect on.person., over 90% of participan.s at MC an. Mn.attested that they were overcome by fear/pan.c. On.measures to cope with an. likely eruption. the followin. order was established at the flan.s of both volcan.es: sen.itization.of population. use of religious (prayers) an. of tradition.l/in.igen.us strategies. In.terms of future copin. strategies, while the males at MC main.ain.d sen.itization.as the favourite option. 62% of the males at Mn.opted for tradition.l/in.igen.us strategies. The female population.at both MC an. Mn.showed a higher preferen.e for religious strategies like prayers.

关键词： Risk Perception Moun. Cameroon Moun. n.iragon.o In.igen.us Buea Goma

The fun.tion.of dopin. n.trogen.on.removin. fluoride with decomposin. La-MOF-n._2:Den.ity fun.tion.l theory calculation.an. experimen.s

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Journ.l of En.iron.en.al Scien.es 2024年第1期135卷 118-129页

作者： Hon.guo Zhan. Kuilin.an.Jia Yan.Qian.Li Yufan. Guo Lei Huan. samuel Raj Babu Arulman. Jian.Luo School of En.iron.en.al Scien.e an. En.in.erin. Guangzhou UniversityGuangzhou 510006China Guan.zhou Un.versity-Lin.opin. Un.versity Research Cen.er on.Urban.Sustain.ble Developmen. Guangzhou UniversityGuangzhou 510006China School of Civil an. En.iron.en.al En.in.erin. Georgia Institute of TechnologyAtlantaGA 30332USA

Fluoride is an.importan. pollutan. in.wastewater,an. adsorption.is an.effective way to remove *** n.trogen.plays an.importan. role in.adsorben. materials,computation.l models were developed to un.erstan. the chan.es in.work fun.tion.resultin. from n.trogen.***-n.C-800℃,was prepared by pyrolyzin. La-MOF-n._(2)to verify the in.luen.e on.the performan.e of removin. fluoride by *** an. electrochemical performan.e tests were performed to characterize La-n.C-800℃.Adsorption.kin.tics,adsorption.thermodyn.mics,in.tial con.en.ration.,pH,an. ion. competition.were in.estigated usin. La-n.C-800℃for fluoride *** addition.den.ity fun.tion.l theory was applied to evaluate the fun.tion.of *** n.trogen.atoms were added,the den.ity of states,partial den.ity of states,population.,an. differen. orbits of charge were calculated to discover deep *** stren.then.d the carbon.structure an. La_(2)O_(3)structure to remove *** addition.n.trogen.can.also act as an.adsorption.site in.the carbon.*** results provide design.ideas for improvin. the performan.e of adsorben. materials by dopin. elemen.s.

关键词： Capacitive deion.zation Fluoride La-MOFs Dopin. n.trogen

Immun. respon.e to in.ctivated bacterial vector carryin. the recombin.n. K39 an.igen.of Leishman.a in.an.um in.mice

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Asian.Pacific Journ.l of Tropical Biomedicin. 2024年第5期14卷 199-206页

作者： Lucelin. S.Araújo Brun. B.Silva Eduarda n.F.n.San.os Arn.ldo S.Bezerra samuel S.Frota Assis R.Mon.en.gro Eridan.O.P.T.Florean.Maurício Fvan.Tilburg Maria Izabel F.Guedes Laboratory of Biotechn.logy an. Molecular Biology Northeast Biotechnology NetworkState University of CearáFortalezaBrazil Faculty of Veterin.ry Medicin. State University of CearáFortalezaBrazil

Objective:To evaluate the immun.logical respon.e elicited by an.in.ctivated bacterial vector carryin. the K39 an.igen.of Leishman.a in.an.um,an. a purified ***:Mice were subjected to the followin. treatmen.s:(1)Purified recombin.n. K39(rK39)protein.at a 20μg dose with complete Freun.’s adjuvan.;(2)In.ctivated Escherichia coli(BL21 DE3)carryin. the K39 protein.at an.equivalen. total protein.con.en. of 200μg;(3)In.ctivated bacteria lackin. the K39 protein.(4)n.n.immun.zed con.rol *** mon.torin. was *** groups were challen.ed by in.raperiton.al in.ection.of 10^(7) Leishman.a in.an.um *** euthan.sia,the liver an. spleen.were collected to an.lyze the levels of Tn.,IFn.γ,IL-12,IL-4,an. ***:Mice immun.zed with purified rK39 or the in.ctivated bacterial vector carryin. the K39 an.igen.of Leishman.a in.an.um showed a lon.-lastin. immun. respon.e with high levels of polyclon.l an.ibodies specifically recogn.zin. the recombin.n. *** IgG1 subclass was the predomin.n. immun.globulin.however,the in.uction.of IgG2a an. the profile of cytokin.s produced were in.icative of the in.uction.of a mixed-type ***:The in.ctivated bacterial vector carryin. the K39 an.igen.as well as the purified an.igen.can.in.uce a lon.-lastin. immun. respon.e in.immun.zed mice,predomin.n.ly favourin. a Th2 profile respon.e.

关键词： Visceral leishman.asis K39 In.ctivated bacterial vector Vaccin. Immun. respon.e Th1 Th2 Leishman.a in.an.um