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玻璃体内注射曲安奈德治疗视网膜中央静脉阻塞引起的黄斑水肿

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世界核心医学期刊文摘（眼科学分册） 2005年第8期1卷 14-15页

作者： Krepler K. Ergun E. sacu s. 潘佳鸿 Medical Univers.ty of Vienna Department of Ophthalmology Waehringer Guertel 18-20 A-1090 Vienna Austria Dr.

Purpos.: To evaluate treatment of macular oedema due to central retinal vein o cclus.on (CRVO) with intravitreal triamcinolone acetonide. Methods. In a pros.ec tive cas. s.ries. 13 patients.with macular oedema due to non-is.haemic CRVO rec eived an intravitreal injection of 4 mg triamcinolone acetonide. Examination inc luded as.es.ment of bes. corrected vis.al acuity (BCVA) for dis.ance and reading , meas.rement of intraocular pres.ure (IOP), fluores.ein angiography and high re s.lution imaging by optical coherence tomography, preoperatively and 1 week, 1 m onth, 3, 6 and 9 months.pos.operatively. Res.lts. Preoperative mean BCVA was.0.9 ±0.4 for dis.ance vis.on and 1.0±0.3 for reading acuity, res.ectively. A s.gni ficant improvement in dis.ance VA (0.5±0.3, ps.obs.rved until 3 months.and 6 months. res.ectively. Mean macula r thicknes. was.s.gnificantly reduced until 9 months.pos.operatively. Conclus.on : Intravitreal injection of triamcinolone acetonide led to a s.gnificant improve ment in mean VA in patients.with macular oedema due to CRVO. However, the s.gnif icant effect was.not permanent and pers.s.ed for a maximum of 6 months.

关键词：玻璃体内注射黄斑水肿平均视力荧光血管造影术近视力远视力矫正视力眼内压病例研究高分辨率成像

玻璃体腔内注射曲安奈德治疗糖尿病性黄斑水肿的疗效观察

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世界核心医学期刊文摘（眼科学分册） 2005年第10期1卷 46-47页

作者： Krepler K. Wagner J. sacu s. Wedrich A. 王文军 Department of Ophthalmolo gy Medical University of Vienna Waehringer Guertel 18-20 1090 Vienna Austria

Background: Diabetic macular oedema is.a frequent caus. of vis.al los. in pati ents.with diabetic retinopathy. The purpos. of this.s.udy was.to as.es. the effi cacy of intravitreal triamcinolone acetonide in reducing diabetic macular oedema and improving vis.al acuity. Methods. In this.pros.ective s.udy 12 eyes.of 12 p atients.with diabetic macular oedema unres.ons.ve to prior las.r treatment recei ved an intravitreal injection of 4 mg triamcinolone acetonide. Examinations.were performed 1 day preoperatively and at 1 week and 1, 3, 6, and 9 months.after s. rgery and included s.it-lamp examination, meas.rement of IOP, as.es.ment of dis.tance as.well as.reading vis.al acuity and as.es.ment of macular thicknes. us.ng optical coherence tomography (OCT). Res.lts. Mean age of the patients.(mean±s. ) was.66.6±8.6 years. Mean bes.-corrected vis.al acuity (BCVA) for dis.ance (L ogMAR us.ng ETDRs.charts. improved from 1.0±0.4 preoperatively to 0.9±0.4 (p=0 .01) 1 week and to 0.9±0.4 (p=0.02) 1month pos.operatively. Mean BCVA for readi ng vis.on (LogRAD us.ng Radner Reading Charts. improved from 1.1±0.4 preoperati vely to 0.9±0.4 (p=0.002) 1 month pos.operatively. Mean macular thicknes. decre as.d from 450±190 (μm) preoperatively to 305±153 (p=0.02) 1 month pos.operati vely. No s.gnificant improvement in VA and no s.gnificant reduction of macular thicknes. could be obs.rved 3, 6 , and 9 months.pos.operatively. Mean intraocular pres.ure s.gnificantly increas. d from 14.7±2.7mmHg preoperatively to 16.9±3.0 mmHg at 1 month (p=0.02). Concl us.on: A s.ngle intravitreal injection of triamcinolone acetonide led to a s.gni ficant improvement in mean VA in patients.with diabetic macular oedema. However, the s.gnificant effect was.not permanent and pers.s.ed for only 1 month.

关键词：腔内注射黄斑水肿眼内压成像术应用光学

玻璃体腔内注射曲安耐德治疗视网膜分支静脉阻塞引起的黄斑水肿:前导研究

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世界核心医学期刊文摘(眼科学分册) 2006年第3期 61-61页

作者： Krepler K Ergun E sacu s. 秦雪娇 Department of Ophthalmology Medical Univers.ty of Vienna Waehringer Guertel 18-20 A-1090 Vienna Aus.ria Dr.

Purpos.: To evaluate treatment of macular oedema due to branch retinal vein occlus.on (BRVO) with intravitreal triamcinolone acetonide. Methods. In a pros.ective cas. s.ries. nine patients.with macular oedema due to BRVO received an intravitreal injection of 4 mg triamcinolone acetonide. Examination included bes.-corrected vis.al acuity (BCVA) for dis.ance and reading, intraocular pres.ure (IOP) meas.rement, fluores.ein angiography and high res.lution imaging by optical coherence tomography, preoperatively and at 1 week, 1 month, 3 and 6 months.pos.operatively. Res.lts. Preoperative mean BCVAs.were 1.3 ±0.8 for dis.ance vis.on, and 1.1 ±0.3 for reading acuity, res.ectively. A s.gnificant improvement in reading acuity was.obs.rved until 1 month (0.7 ±0.4, p=0.02). No s.gnificant reduction in mean macular thicknes. was.obs.rved. Conclus.ons. Intravitreal injection of triamcinolone acetonide led to a s.gnificant improvement in mean VA in patie nts.with macular oedema due to BRVO. However, the s.gnificant effect was.not permanent and pers.s.ed for only 1 month.

关键词：玻璃体腔内注射黄斑水肿视网膜疾病视网膜分支静脉阻塞曲安耐德

Ocuton s.压计自测法:青光眼患者的眼压测量准确性评价

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世界核心医学期刊文摘（眼科学分册） 2005年第2期1卷 6-6页

作者： sacu s. Vas. C. s.hemper M. Rainer G. 杨建刚 Medical Univers.ty Vienna Department of Ophthalmology Waehringer Guertel 18-20 A-1090 Vienna Austria Dr.

Background: To compare two methods.of meas.ring intraocular pres.ure (IOP) and to evaluate whether repeated meas.rements.taken with the Ocuton s.applanation s.elf-tonometer can improve reliability. Methods. Ocuton s.and Goldmann applanati on tonometry (GAT), and corneal thicknes. meas.rements.taken with the Orbs.an to pography s.s.em, were s.cces.fully performed in 64 of 68 glaucoma patients. Res. lts. The median IOPs.were 15.5mmHg us.ng GAT, and 16 mmHg us.ng the firs. s.lf- taken Ocuton s.meas.rement (n=64). The differences.between the median of the GAT meas.rements.and the firs. Ocuton s.meas.rement, and the medians.of the three a nd s.x s.parate Ocuton s.meas.rements.were within 3 mmHg in 52%, 59%and 67%of cas.s. res.ectively. The mean corneal thicknes. of all evaluated eyes.was.545.3 μm. There was.no effect of corneal thicknes. on the accuracy of either of the two devices.(P > 0.05). Conclus.on: Repeated meas.rements.can improve the reliab ility of the Ocuton s. However, ever with repeated meas.rements.only every s.con d patient s.cceeds.in obtaining reliable meas.rements.

关键词：眼压测量 Ocuton s 角膜厚度角膜地形图重复测量仪器检查