光学材料和外观设计对前囊混浊和撕囊收缩的影响

作     者：Sacu S. Menapace R. Findl O. 杨秀梅(译) 

作者机构：不详 Department of Ophthalmology Medical University of Vienna Waehringer Guertel 18-20 A-1090 Vienna Austria 

出 版 物：《世界核心医学期刊文摘（眼科学分册）》 (Digest of the World Core Medical Journals:Ophthalmology)

年 卷 期：2006年第2卷第6期

页      面：7-8页

学科分类：1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100212[医学-眼科学] 10[医学] 

主　　题：撕囊面积 外观设计 光学材料 混浊程度 收缩量 前囊 丙烯酸树脂 IOLs 临床试验研究 奥地利维也纳 

摘      要：PURPOSE: To examine the influence of optic material (silicone and hydrophobic acrylic) and haptic design (one-piece and three-piece open loop) of sharp optic edge intraocular lenses (IOL) on anterior capsule opacification (ACO) and capsulorrhexis contraction. DESIGN: Randomized,controlled,double-blind clinical trial with intraindividual comparison. METHODS: This study was performed at the Department of Ophthalmology,Medical University of Vienna,Austria,and comprised 210 eyes of 105 patients with bilateral age-related cataract. In group 1 (n=53 patients),a three-piece acrylic IOL was compared with a three-piece silicone IOL. In group 2 (n=52 patients),the three-piece acrylic IOL was compared with the one-piece acrylic IOL. One year after the operation,standardized digital slit-lamp images of ACO were taken; 1 week and 1 year after the operation,digital retroillumination images were taken to assess capsulorrhexis size. The intensity of ACO was graded objectively (score,0% to 100% ),and the capsulorrhexis area (square millimeters) was determined objectively. RESULTS: One year after surgery,the mean ACO score was 21% for the acrylic and 20% for the silicone IOL (P =.4) in group 1 and 18% for both the three-piece and one-piece acrylic IOLs (P=.87) in group 2. Concerning the amount of capsulorrhexis contraction,there was no significant difference between the IOL types that were evaluated in this study (after Bonferroni-Holm correction,P .05). CONCLUSION: In the hydrophobic sharp optic edge IOLs that were examined,neither the optic material nor the haptic design had an influence on the amount of ACO or capsulorrhexis contraction.