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The study on the levels of sIL-2R and TNF-αin the aqueous of Rhesus M onkeyseyesim planted w ith F-heparin surface m odified iols

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Chinese Journal of Biomedical Engineering(English Edition) 1999年第2期8卷 17-20页

作者： WANGGui-qin GUHan-qing YUANJia-qin International Intraocular Implant Training Centre Tianjin Medical UniversityTianjin 300070China

Objective: To study the levels of sIL 2R and TNF α in the aqueous of Rhesus Monkeys eyes and the biocompatibility implanted with F heparin modified intraocular lens(iols).Methods: Twelve monkeys were classified into 3 groups which were normal,control and experimental *** iols and modified PMMA iols were implanted into monkeys*** from anterior chamber was aspirated at 15,30,60,90,180 and 360 *** level of sIL 2R was measured by ELISA and TNF α by ***: The level of sIL 2R in aqueous increased at 15 day,reached the highest level at 30 day and returned to normal at 90 *** 15,30 days the level of sIL 2R in aqueous in control group was higher than that in experimental *** content of TNF α in aqueous was the highest at 15 day and returned at 60 *** 15 day the content of TNF α in control group was higher and decreased slower than that in experimental ***: F heparin modified iols with better biocompatibility induced lower foreign body reaction and inflammatory reaction than that of polymethylmethacrylate (PMMA) iols.

关键词： F heparin surface modification iols sIL 2R TNF α biocompatibility

Piggyback iols植入联合小梁切除术治疗小眼球并发闭角型青光眼一例

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眼科研究 2005年第6期23卷 606-606页

作者：盛耀华叶向彧上海第二医科大学附属新华医院眼科 200092

小眼球并发闭角型青光眼主要是由于相对大的晶状体使晶状体-虹膜膈前移,产生瞳孔阻滞并进一步导致房角狭窄及粘连所致.我们采用piggyback iols植入联合小梁切除术治疗了1例小眼球并发闭角型青光眼患者,效果满意,报告如下。

关键词：闭角型青光眼 Piggyback 小梁切除术 iols 小眼球并发治疗联合植入 piggyback

有晶状体眼前房型人工晶状体植入术矫正屈光不正的研究进展

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微创医学 2007年第3期2卷 219-222页

作者：陈迎迎谭少健广西医科大学第一附属医院眼科南宁市530021

矫正屈光不正的手术方法主要有角膜屈光手术和有晶状体眼人工晶状体(phakic Intraocular Lenses,PIOL)植入,其中PIOL又包括了前房型PIOL(anterior chamber phakic,ACPiols)和后房型PIOL,与后房型手术相比,ACP-iols植入术有其自身的优势... 详细信息

矫正屈光不正的手术方法主要有角膜屈光手术和有晶状体眼人工晶状体(phakic Intraocular Lenses,PIOL)植入,其中PIOL又包括了前房型PIOL(anterior chamber phakic,ACPiols)和后房型PIOL,与后房型手术相比,ACP-iols植入术有其自身的优势和特点,本文对此作一综述.

关键词：前房型人工晶状体植入术矫正屈光不正有晶状体眼角膜屈光手术 phakic 手术方法 iols 后房型

扁平部玻璃体切除联合经巩膜缝线固定后房型人工晶状体移植的长期效果

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世界核心医学期刊文摘（眼科学分册） 2006年第5期2卷 12-13页

作者： Vote B.J. Tranos P. Bunce C. L. Da Cruz 王静波 Department of Vitreoretinal Surgery Moorfields Eye Hospital London EC1V 2PD United Kingdom Dr.

PURPOSE: To investigate the long-term visual outcome and the complication rate following transscleral suture fixation of posterior chamber intraocular lenses (sutured PC-iols). DESIGN: A retrospective case-series descriptive ***: Records of patients who underwent combined pars plana vitrectomy and sutured PC-iols at Moorfields Eye Hospital and who had at least 12 months of follow-up were examined for recorded complications. RESULTS: Sixty-one eyes of 48 patients (33 males and 15 females) were identified and included in the analysis, with mean follow-up of 6 years. The mean final best-corrected visual acuity remained at preoperative levels (P=.211) and was largely determined by the underlying ocular pathology before sutured PC-IOL. Overall 30 of 61 (49%) eyes, two or more procedures were performed to reverse a significant peri-or postoperative complication. Breakage of polypropylene sutures was the main indication accounting for 17 of 30 (57%) of those reoperations. Subgroup analysis showed that younger patients were more likely to suffer the above complication (P=.009). The multivariate analysis also showed that longer follow-up was significantly associated with suture breakage (P=.014), with the mean time to breakage approximately 4 years after surgery. CONCLUSIONS: Long-term follow-up of patients undergoing sutured PC-iols appears to be associated with a high rate of postoperative complications and significant need for further surgery,which should be discussed during their informed consent process.

关键词：巩膜缝线固定晶状体移植玻璃体切除后房型扁平部长期效果人工联合并发症发生率 iols

波阵面矫正人工晶状体偏位对高阶象差眼的影响

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美国医学会眼科杂志（中文版） 2006年第3期18卷 176-180页

作者： Li Wang Douglas D. Koch 陈旭（译）朱志忠（校） Department of Ophthalmology Baylor College of Medicine Houston Tex

目的：评估非球面人工晶状体（iols）偏位和波阵面（波前）矫正人工晶状体对高阶象差（HOAs）（3至6阶）眼的理论性作用。方法：伴有4阶球面象差的非球面人工晶状体仅（-0．287μm 6mm瞳孔）。一个有相同幅度高阶象差的波阵面矫正人工... 详细信息

目的：评估非球面人工晶状体（iols）偏位和波阵面（波前）矫正人工晶状体对高阶象差（HOAs）（3至6阶）眼的理论性作用。方法：伴有4阶球面象差的非球面人工晶状体仅（-0．287μm 6mm瞳孔）。一个有相同幅度高阶象差的波阵面矫正人工晶状体和人工晶状体侧移1mm偏离中心形成的角膜高阶象差。结合角膜和偏位人工晶状体HOAs的计算。测出瞳孔3-6mm时的残余HOAs。基于残余HOAs。定出三个标准的光学质量：Marechal标准。衍射光学系统象差小于λ/14；P10,本研究中角膜HOAs小于第十个百分率；减小的HOA,残留眼部HOAs小于相应的角膜HOAs。结果：在94例年龄40—80岁患者的154只眼中。模拟植入非球面iols和波阵面矫正iols,非球面IOL居中和瞳孔6mm眼。未遇见Marechal标准眼。而P10和减小的HOA眼。分别为46％和93％。植入波阵面矫正IOL,对瞳孔6mm眼而言。50％眼处于减小的HOA标准,中心定位需要0．47mm；90％眼中心定位。Marechal标准需要0．04mm。P10需要0．36mm,减小的HOA标准,需要0．48mm。结论：为达到最佳波阵面矫正人工晶状体的视觉效果。出色的中央定位是需要的。临床联系：用现代外科技术。植入非球面iols和波阵面矫正iols在瞳孔6mm时。将能减低总的眼部象差低于角膜象差分别达45％和86％。

关键词：人工晶状体波阵面象差矫正 iols 中心定位非球面 P10

光学材料和外观设计对前囊混浊和撕囊收缩的影响

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世界核心医学期刊文摘（眼科学分册） 2006年第6期2卷 7-8页

作者： Sacu S. Menapace R. Findl O. 杨秀梅(译) 不详 Department of Ophthalmology Medical University of Vienna Waehringer Guertel 18-20 A-1090 Vienna Austria

PURPOSE: To examine the influence of optic material (silicone and hydrophobic acrylic) and haptic design (one-piece and three-piece open loop) of sharp optic edge intraocular lenses (IOL) on anterior capsule opacification (ACO) and capsulorrhexis contraction. DESIGN: Randomized,controlled,double-blind clinical trial with intraindividual comparison. METHODS: This study was performed at the Department of Ophthalmology,Medical University of Vienna,Austria,and comprised 210 eyes of 105 patients with bilateral age-related cataract. In group 1 (n=53 patients),a three-piece acrylic IOL was compared with a three-piece silicone IOL. In group 2 (n=52 patients),the three-piece acrylic IOL was compared with the one-piece acrylic IOL. One year after the operation,standardized digital slit-lamp images of ACO were taken; 1 week and 1 year after the operation,digital retroillumination images were taken to assess capsulorrhexis size. The intensity of ACO was graded objectively (score,0% to 100% ),and the capsulorrhexis area (square millimeters) was determined objectively. RESULTS: One year after surgery,the mean ACO score was 21% for the acrylic and 20% for the silicone IOL (P =.4) in group 1 and 18% for both the three-piece and one-piece acrylic iols (P=.87) in group 2. Concerning the amount of capsulorrhexis contraction,there was no significant difference between the IOL types that were evaluated in this study (after Bonferroni-Holm correction,P > .05). CONCLUSION: In the hydrophobic sharp optic edge iols that were examined,neither the optic material nor the haptic design had an influence on the amount of ACO or capsulorrhexis contraction.

关键词：撕囊面积外观设计光学材料混浊程度收缩量前囊丙烯酸树脂 iols 临床试验研究奥地利维也纳

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散光矫正手术及最新进展

眼视光学杂志 2001年第1期3卷 59-61页

作者：王雁赵堪兴天津市眼科医院天津300020

目的 :在最近的十年中 ,像近视眼手术一样 ,散光治疗的发展速度很快。本文就散光性角膜切开术的 (AstigmaticKeratotomyAK)现代作用及近年出现的准分子激光表面角膜散光术 (PhotoastigmaticRefractiveKera tectomy,PARK)、准分子激光原... 详细信息

目的 :在最近的十年中 ,像近视眼手术一样 ,散光治疗的发展速度很快。本文就散光性角膜切开术的 (AstigmaticKeratotomyAK)现代作用及近年出现的准分子激光表面角膜散光术 (PhotoastigmaticRefractiveKera tectomy,PARK)、准分子激光原位角膜磨镶术 (LaserinSituKeratomileusisLASIK)、激光角膜热成形术 (Laserthermokeratoplasty ,LTK)等手术予以综述。并涉及更新的手术方法如眼内晶状体植入 (iols)等。而个体化切削和波前引导等新技术的引用会使散光手术达到理想视觉效果。

关键词：散光对比研究综述文献矫正手术 AK PARK LASIK LTK iols