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Detection of oxidative stress and DNA damage in freshwater snail Lymnea leuteola exposed to profenofos

Frontiers of Environmental Science & Engineering 2018年第5期12卷 181-187页

作者： Daoud Ali Huma Ali Saud Alifiri saad Alkahtani Abdullah A Alkahtane Shaik Althaf Huasain Department of Zoology College of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia 2 Department of ChemistryMANITBhopal 462003India

Extensive production and use of organophosphate pesticide in agriculture,has risen concerned about its ecotoxicity and risk assessment of insecticides,which are more ***,the present investigation was aimed to study the induction of oxidative stress and DNA damage by organophosphate insecticide profenofos(PFF)in freshwater snail Lymnea luteola(***).The median lethal value(96 h LC50)of PFF was estimated as 1.26 mg/L for *** in a semi-static system and on the basis of LC50 value three concentrations viz.,0.126(1/10 of LC50,Sublethal I),0.63(1/2 of LC50,Sublethal II)and 0.84 mg/L(2/3 of LC50,Sublethal III)were *** were exposed to above-mentioned concentrations of PFF along with solvent control(acetone)and negative control for 96 *** haemolymph was collected at 24 and 96 h of after *** heamolymph of PFF exposed snail,lipid peroxide,glutathione reduced glutathione S transferase and superoxide dismutase activities at the tested concentrations significantly differ from those in the *** genotoxicity induced in hemocytes of treated snails was measured by alkaline single cell gel electrophoresis *** data of this experiment demonstrated significantly enhancement of oxidative stress and DNA damage in the treated snails as compared to ***,we observed statistically significant correlations of ROS with DNA damage(%tail DNA)(R^(2)=0.9708)for 24 h and DNA damage(R^(2)=0.9665)for 96 *** of the current experiment can be useful in risk evaluation of PFF among aquatic *** study confirmed the use of comet assay for in vivo laboratory experiments using freshwater snail for selecting the toxic potential of industrial chemicals and environmental contaminants.

关键词： Acute toxicity Profenofos ROS oxidative stress DNA damage Lymnea luteola

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Control of animal brucellosis: the Malaysian experience

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Asian Pacific Journal of Tropical Medicine 2016年第12期9卷 1111-1115页

作者： M.Zamri-saad M.I.Kamarudin Research Centre for Ruminant Diseases Faculty of Veterinary MedicineUniversiti Putra Malaysia Department of Veterinary Services Malaysia Ministry of Agriculture and Agro-based Industry

Brucellosis is a zoonotic disease characterized by reproductive failure in animals and undulent fever in humans. In cattle, it is caused by Brucella abortus while in goats by Brucella melitensis, the main cause of brucellosis in humans. Brucellosis in livestock has been associated with importation of animals from breeder herd of unknown disease status. The prevalence of bovine brucellosis Brucella abortus in 2014 ranged between 1%-2% in Thailand and Indonesia, and 4%-5% in Malaysia and Myanmar. Prevalence of goat brucellosis Brucella melitensis is approximately 1% in Malaysia and Thailand. ‘Test-and-slaughter' is the general policy against brucellosis adopted by most ASEAN countries to eradicate the disease. Under this program, the Rose Bengal Plate Test(RBPT) is used as the screening test to identify infected farm/herd while the Complement Fixation Test(CFT) is the confirmatory test. The test-and-slaughter eradication strategy that was implemented since 1979 had managed to keep the prevalence rate to less than 5%, from 3.3% in 1979, 0.23% in 1988, 1% in 1998 and 5% in 2016. The test-and-slaughter program seemed effective in reducing the prevalence of brucellosis but was unable to eradicate the disease due to several factors, which include failure to locate and identify the remaining affected animals and to control their movement, importation of breeder animals from non-brucellosis free countries and lack of participation by the farmers following unrealiable test results. To support the eradication policy, research activities since 1980 s have suggested combinations of serological tests to improve diagnosis while surveillance should be focused on hotspots areas. The prevalence can be further reduced by strictly sourcing breeder animals from brucella-free areas or countries.

关键词： Brucellosis Animal Control

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PID Controller Tuning for a Multivariable Glass Furnace Process by Genetic Algorithm

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International Journal of Automation and computing 2016年第1期13卷 64-72页

作者： Kumaran Rajarathinam James Barry Gomm Ding-Li Yu Ahmed saad Abdelhadi Mechanical Engineering and Materials Research Centre Control Systems Group School of EngineeringLiverpool John Moores University

Standard genetic algorithms （SGAs） are investigated to optimise discrete-time proportional-integral-derivative （PID） con- troller parameters, by three tuning approaches, for a multivariable glass furnace process with loop interaction. Initially, standard genetic algorithms （SGAs） are used to identify control oriented models of the plant which are subsequently used for controller optimisa- tion. An individual tuning approach without loop interaction is considered first to categorise the genetic operators, cost functions and improve searching boundaries to attain the desired performance criteria. The second tuning approach considers controller parameters optimisation with loop interaction and individual cost functions. While, the third tuning approach utilises a modified cost function which includes the total effect of both controlled variables, glass temperature and excess oxygen. This modified cost function is shown to exhibit improved control robustness and disturbance rejection under loop interaction.

关键词： Genetic algorithms control optimisation decentralised control proportional-integral-derivative (PID) control modifiedcost function multivariable process loop interaction.

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Dietary effects of A zolla pinnata combined with exogenous digestive enzyme(Digestin^(TM)) on growth and nutrients utilization of freshwater prawn, Macrobrachium rosenbergii(de Man 1879)

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Journal of Oceanology and Limnology 2018年第4期36卷 1434-1441页

作者： GODA Ashraf saad Amal HANAFY Mohamed SHARAWY Zaki EL-HAROUN Ehab Aquaculture Division National Institute of Oceanography and Fisheries (NIOF) Institute of Oceanology Chinese Academy of Sciences Division of Aquaculture College of Agriculture Food Science and Sustainable Systems Kentucky State University

The present study was conducted to evaluate the effect of either individual or combined wheat bran(WB) replacement with Azolla pinnata supplemented with Digestin^(TM) in the diet of freshwater prawn, Macrobrachium rosenbergii Postlarvae(PL) on growth performance, nutrient utilization, chemical body composition and survival(%). Experimental diets were a wheat bran-soybean based diet with no Azolla and Digestin^(TM)(control, T_1), and diets containing 17% Azolla supplemented with Digestin^(TM) 0%(T_2), 1%(T_3), 2%(T_4) and 3%(T 5). Each experimental diet was allocated into three tanks(6 m^3/tank) fed for 12 wks. Each tank was subdivided into three equal pens by nets(2 m^3) and stoked with 84 PL/m^2. The experimental diets were readily consumed by prawns PLs where both high growth and good feed efficiency were achieved for all diets. The results showed that the diets containing A. pinnata supplemented with Digestin? at the level up to 3% have the higher growth and better nutrient utilization than the control diet. No differences were observed for moisture and protein content among the experimental diets. However, the highest protein content was observed on prawns fed on diets T_1 and T 5 respectively, while the lowest value was recorded for T_4 diet. The results also show that prawn PLs fed the diets contain A. pinnata and supplemented with Digestin^(TM) recorded the highest values of body lipid content compared to the control diet. Feed efficiency and economic conversion rate(ECR) values show that economic performance and the cost-effectiveness of the A. pinnata supplemented with up to 3% Digestin^(TM) recorded the highest net return, and therefore it is recommended for prawn, M. rosenbergii PL's. These results are clearly indicating that A. pinnata have a good potential for use in prawn diets at reasonable levels than other conventional diets.

关键词： Azolla meal enzymes growth performance economic analysis feed efficiency

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Microwave-assisted catalytic oxidative desulfurization of gasoil fuel using synthesized CuO-ZnO nanocomposites

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燃料化学学报 2019年第9期47卷 1075-1082页

作者： Mustafa H.Fadhil saad H.Ammar Marwa F.Abdul Jabbar Chemical Engineering Department Al-Nahrain University

Recently, organosulfur removal from liquid petroleum fuels is very significant aspect of environment protecting and fuel cell requests. Therefore, improved approaches to remove sulfur are still essential. In the present work, a simple catalytic oxidative desulfurization (CODS) system for Iraqi gasoil fraction has been successfully developed using CuO-ZnO nanocomposites as catalysts, and H 2O 2 as oxidant under microwave irradiation. The main reaction parameters influencing sulfur conversion including microwave power, irradiation time, catalyst dosage and H 2O 2 to gasoil volume ratio have been investigated. The CuO-ZnO nanocomposites was synthesized with different weight ratios and characterized by XRD, FE-SEM, AFM and BET surface area methods. The results reveal that, high sulfur conversion (93%) has been achieved under suitable conditions of microwave CODS as follows: microwave power of 540 W, irradiation time of 15 min, catalyst dosage of 8 g/L (0.4 g), and H 2O 2 ∶gasoil volume ratio of 0.3. The catalyst reusability shows that the synthesized catalyst can be reused five times without an important loss in its activity.

关键词： microwave oxidative desulfurization nanocomposites catalyst gasoil

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Impact of preterm birth and low birth weight on medical conditions, medication use and mortality among neonates: a prospective observational cohort study

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World Journal of Pediatrics 2019年第3期15卷 281-288页

作者： Krishna Undela Bashar Talal saad Mohammed Parthasarathi Gurumurthy Srinivasa Murthy Doreswamy Department of Pharmacy Practice JSS College of Pharmacy.JSS Academy of Higher Education and ResearchSS NagaraMysuru.Karnataka 570 015.India Department of Pediatrics JSS Medical College and Hospital.JSS Academy of Higher Education and ResearchMahatma Gandhi RoadMysuruKarnataka 570 004India

Background There is a paucity of studies conducted in India on neonatal outcomes of preterm birth and low birth ***,we aimed to assess the impact of preterm birth and low birth weight on medical conditions,medication use and mortality among *** A prospective observational cohort study was conducted at the neonatal intensive care unit (NICU) over a period of 9 *** of either sex,admitted to NICU and who received at least one medication were enrolled in the *** and demographic data,reason(s) for NICU admission,diagnoses,medications prescribed,medication-related problems,discharge status and the direct medical cost were documented and *** Four hundred and five neonates Were included in the study:60.5% were boys,32.7% were preterm and 44.2% were born *** sepsis (n =125,16.7%),unconjugated hyperbilirubinemia (n =83,11.1%) and respiratory distress syndrome (n =62,8.3%) were the most common medical conditions and were significantly more common among preterm and underweight *** half of the medications prescribed were anti-infectives for systemic use (n =1310,47.4%).The mean number of medications received by neonates increased from term to extremely preterm (5.2-15.0) and normal birth weight to extremely low birth weight (5.0-14.9).Mortality rate was significantly higher among extremely preterm (66.7%),and very preterm (15.2%) neonates compared to term (2.9%) *** median direct medical cost for NICU admission was INR 21,430 (USD 331).Conclusion Medical conditions,medications prescribed and mortality rate were significantly higher among preterm and underweight neonates admitted to NICU.

关键词： Low birth weight Medical conditions Medications Mortality Preterm birth

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Geotechnical forensic investigation of a slope failure on silty clay soil--A case study

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Frontiers of Structural and Civil Engineering 2020年第2期14卷 501-517页

作者： Mohammad Abubakar NAVEED Zulfiqar ALI Abdul QADIR Umar Naveed LATIF saad HAMID Umar SARWAR Military College of Engineering National University of Sciences and TechnologyRisalpur 24080Pakistan School of Civil Environmental and Mining EngineeringThe University of AdelaideAdelaibe 5096Australia

Qila Bala Hisar is one of the noteworthy places of Peshawar,Khyber *** fort was constructed on a flled ground during the 18th century and it was renovated several times by the occupants ever ***,due to an earthquake of magnitude 7.3,the upper part of the south-western wall of the fort *** collapse of the wall was attributed to the failure of the retained *** research was undertaken to characterize the slope material,study causal factors of failure and evaluate remedial *** investigation involved conventional field and laboratory testing and geophysical investigation using electrical resistivity technique to evaluate the nature of ***,X-ray Diffraction and Scanning Electron Microscopy was used to study the slope material at a molecular level to evaluate the existence of swelling *** analysis has shown that excessive seepage of water caused by the poor maintenance of runoff and sewage drains is the causal factor triggered by the seismic event.A remedial strategy involving soil nails,micro piles and improvement of the surface drainage is recommended.

关键词： forensic geotechnical investigation slope failure slope analysis finite element method numerical analysis seismic loading Qila Bala Hisar

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Analytical Comparison of Resource Search Algorithms in Non-DHT Mobile Peer-to-Peer Networks

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Computers, Materials & Continua 2021年第7期68卷 983-1001页

作者： Ajay Arunachalam Vinayakumar Ravi Moez Krichen Roobaea Alroobaea Jehad saad Alqurni Centre for Applied Autonomous Sensor Systems(AASS) Örebro UniversityÖrebroSweden Center for Articial Intelligence Prince Mohammad Bin Fahd UniversityKhobarSaudi Arabia Faculty of CSIT Al-Baha UniversitySaudi Arabia ReDCAD LaboratoryUniversity of SfaxTunisia Department of Computer Science College of Computers and Information TechnologyTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Department of Education Technologies College of EducationImam Abdulrahman Bin Faisal UniversitySaudi Arabia

One of the key challenges in ad-hoc networks is the resource discovery *** efciently&quickly the queried resource/object can be resolved in such a highly dynamic self-evolving network is the underlying question?Broadcasting is a basic technique in the Mobile Ad-hoc Networks(MANETs),and it refers to sending a packet from one node to every other node within the transmission *** is a type of broadcast where the received packet is retransmitted once by every *** naive ooding technique oods the network with query messages,while the random walk scheme operates by contacting subsets of each node’s neighbors at every step,thereby restricting the search *** earlier works have mainly focused on the simulation-based analysis of ooding technique,and its variants,in a wired network ***,there have been some empirical studies in peer-to-peer(P2P)networks,the analytical results are still lacking,especially in the context of mobile P2P *** this article,we mathematically model different widely used existing search techniques,and compare with the proposed improved random walk method,a simple lightweight approach suitable for the non-DHT *** provide analytical expressions to measure the performance of the different ooding-based search techniques,and our proposed *** analytically derive 3 relevant key performance measures,i.e.,the *** of steps needed to nd a resource,the probability of locating a resource,and the *** of messages generated during the entire search process.

关键词： Mathematical model MANET P2P networks P2P MANET unstructured search algorithms Peer-to-Peer ad-hoc ooding random walk resource discovery content discovery mobile peer-to-peer broadcast peer

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A System of Sylvester-type Quaternion Matrix Equations with Ten Variables

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Acta Mathematica Sinica,English Series 2022年第8期38卷 1399-1420页

作者： Meng Yan XIE Qing Wen WANG Zhuo Heng HE Mehany Mahmoud saad Department of Mathematics Shanghai UniversityShanghai 200444P.R.China

This paper studies a system of three Sylvester-type quaternion matrix equations with ten variables A_(i)X_(i)+Y_iB_(i)+C_(i)Z_(i)D_(i)+F_(i)Z_(i+1)G_(i)=E_(i),i=1,3^-.We derive some necessary and sufficient conditions for the existence of a solution to this system in terms of ranks and Moore–Penrose inverses of the matrices *** present the general solution to the system when the solvability conditions are *** applications of this system,we provide some solvability conditions and general solutions to some systems of quaternion matrix equations involvingφ-***,we give some numerical examples to illustrate our *** findings of this paper extend some known results in the literature.

关键词： Quaternion matrix equation φ-Hermitian solution general solution solvability

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Prediction of Vibration Characteristics in Beam Structure Using Sub-Scale Modeling with Experimental Validation

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Chinese Journal of Mechanical Engineering 2015年第5期28卷 928-934页

作者： ZAI Behzad Ahmed SAMI saad KHAN M Amir AHMAD Furqan PARK Myung Kyun Structure Design and Development Directorate Institute of Space Technology Department of Civil and Environmental Engineering KAIST Department of Mechanical Engineering Myongji University

Geometric or sub-scale modeling techniques are used for the evaluation of large and complex dynamic structures to ensure accurate reproduction of load path and thus leading to true dynamic characteristics of such structures. The sub-scale modeling technique is very effective in the prediction of vibration characteristics of original large structure when the experimental testing is not feasible due to the absence of a large testing facility. Previous researches were more focused on free and harmonic vibration case with little or no consideration for readily encountered random vibration. A sub-scale modeling technique is proposed for estimating the vibration characteristics of any large scale structure such as Launch vehicles, Mega structures, etc., under various vibration load cases by utilizing precise scaled-down model of that dynamic structure. In order to establish an analytical correlation between the original structure and its scaled models, different scale models of isotropic cantilever beam are selected and analyzed under various vibration conditions（ i.e. free, harmonic and random） using finite element package ANSYS. The developed correlations are also validated through experimental testing The prediction made from the vibratory response of the scaled-down beam through the established sets of correlation are found similar to the response measured from the testing of original beam structure. The established correlations are equally applicable in the prediction of dynamic characteristics of any complex structure through its scaled-down models. This paper presents modified sub-scale modeling technique that enables accurate prediction of vibration characteristics of large and complex structure under not only sinusoidal but also for random vibrations.

关键词： sub-scale modeling resonance frequency vibration characteristics scale factors power spectral density

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