检索结果-南通市图书馆

Detection of oxidative stress and DNA damage in freshwater snail Lymnea leuteola exposed to profenofos

Frontiers of Environmental Science & Engineering 2018年第5期12卷 181-187页

作者： Daoud Ali Huma Ali Saud Alifiri saad alkahtani Abdullah A Alkahtane Shaik Althaf Huasain Department of Zoology College of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia 2 Department of ChemistryMANITBhopal 462003India

Extensive production and use of organophosphate pesticide in agriculture,has risen concerned about its ecotoxicity and risk assessment of insecticides,which are more ***,the present investigation was aimed to study the induction of oxidative stress and DNA damage by organophosphate insecticide profenofos(PFF)in freshwater snail Lymnea luteola(***).The median lethal value(96 h LC50)of PFF was estimated as 1.26 mg/L for *** in a semi-static system and on the basis of LC50 value three concentrations viz.,0.126(1/10 of LC50,Sublethal I),0.63(1/2 of LC50,Sublethal II)and 0.84 mg/L(2/3 of LC50,Sublethal III)were *** were exposed to above-mentioned concentrations of PFF along with solvent control(acetone)and negative control for 96 *** haemolymph was collected at 24 and 96 h of after *** heamolymph of PFF exposed snail,lipid peroxide,glutathione reduced glutathione S transferase and superoxide dismutase activities at the tested concentrations significantly differ from those in the *** genotoxicity induced in hemocytes of treated snails was measured by alkaline single cell gel electrophoresis *** data of this experiment demonstrated significantly enhancement of oxidative stress and DNA damage in the treated snails as compared to ***,we observed statistically significant correlations of ROS with DNA damage(%tail DNA)(R^(2)=0.9708)for 24 h and DNA damage(R^(2)=0.9665)for 96 *** of the current experiment can be useful in risk evaluation of PFF among aquatic *** study confirmed the use of comet assay for in vivo laboratory experiments using freshwater snail for selecting the toxic potential of industrial chemicals and environmental contaminants.

关键词： Acute toxicity Profenofos ROS oxidative stress DNA damage Lymnea luteola

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Elucidating the molecular basis of ATP-induced cell death in breast cancer: Construction of a robust prognostic model

引用

World Journal of Clinical Oncology 2024年第2期15卷 208-242页

作者： Hao-Ling Zhang Sandai Doblin Zhong-Wen Zhang Zhi-Jing Song Babu Dinesh Yasser Tabana DahhamSabbar saad Mowaffaq Adam ahmed Adam Yong Wang Wei Wang Hao-Long Zhang Sen Wu Rui Zhao Barakat Khaled Department of Biomedical Sciences Advanced Medical and Dental InstituteUniversiti Sains MalaysiaPenang 13200Malaysia School of Public Health Gansu University of Chinese MedicineLanzhou 730000Gansu ProvinceChina Clinical College of Chinese Medicine Gansu University of Chinese MedicineLanzhou 730000Gansu ProvinceChina Faculty of Pharmacy and Pharmaceutical Sciences University of AlbertaEdmonton AB T6G 2E1Canada Department of Science University of Technology and Applied Sciences RustaqRustaq 10 P.C.329Oman Department of Chemistry and Biochemistry San Diego State UniversitySan DiegoCA 92182United States Department of Pathology Center Gansu University of Chinese MedicineLanzhou 730000Gansu ProvinceChina College of Acupuncture-moxibustion and Tuina Gansu University of Chinese MedicineLanzhou 730000Gansu ProvinceChina Universiti Sains Malaysia Advanced Medical and Dental InstitutePenang 13200Malaysia Department of Biomedical Science Universiti Sains MalaysiaPenang 13200Malaysia

BACKGROUND Breast cancer is a multifaceted and formidable disease with profound public health *** demise mechanisms play a pivotal role in breast cancer pathogenesis,with ATP-triggered cell death attracting mounting interest for its unique specificity and potential therapeutic *** To investigate the impact of ATP-induced cell death(AICD)on breast cancer,enhancing our understanding of its *** The foundational genes orchestrating AICD mechanisms were extracted from the literature,underpinning the establishment of a prognostic ***,a microRNA(miRNA)prognostic model was constructed that mirrored the gene-based prognostic *** between high-and low-risk cohorts within mRNA and miRNA characteristic models were scrutinized,with the aim of delineating common influence mechanisms,substantiated through enrichment analysis and immune infiltration *** The mRNA prognostic model in this study encompassed four specific mRNAs:P2X purinoceptor 4,pannexin 1,caspase 7,and cyclin *** miRNA prognostic model integrated four pivotal miRNAs:hsa-miR-615-3p,hsa-miR-519b-3p,hsa-miR-342-3p,and hsa-miR-324-3p.B cells,CD4+T cells,CD8+T cells,endothelial cells,and macrophages exhibited inverse correlations with risk scores across all breast cancer ***,Kyoto Encyclopedia of Genes and Genomes analysis revealed that genes differentially expressed in response to mRNA risk scores significantly enriched 25 signaling pathways,while miRNA risk scores significantly enriched 29 signaling pathways,with 16 pathways being jointly *** Of paramount significance,distinct mRNA and miRNA signature models were devised tailored to AICD,both potentially autonomous prognostic *** study's elucidation of the molecular underpinnings of AICD in breast cancer enhances the arsenal of potential therapeutic tools,offering an unparalleled window for innovative ***,this paper revea

关键词： ATP-induced cell death mRNA miRNA Prognostic model Breast cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cloning and characterization of 66 kDa streptavidin-binding peptides(SBP)of Pisum sativum *** specific to ***

引用

BIOCELL 2019年第3期43卷 155-166页

作者： MAHMOUD MOUSTAFA saad ALAMRI TAREK TAHA ALI SHATI SULAIMAN ALRUMMAN MOHAMED alkahtani Department of Biology College of ScienceKing Khalid University9004AbhaKingdom of Saudi Arabia Department of Botany Faculty of ScienceSouth Valley UniversityQenaEgypt Environmental Biotechnology Department Genetic Engineering and Biotechnology Research Institute(GEBRI)City of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab City21934AlexandriaEgypt

The aim of the current research was to clone and to characterize the partial 66 kDa streptavidin-binding peptide(SBP)found in the germinated embryos of Pisum sativum *** pea(*** ***)embryos possess prominent 66 kDa SBPs that gradually disappeared after few hours of germination in germinated embryos,but not in the *** total RNA was isolated from embryos of *** but could not be isolated from the *** partial nucleotides sequences of 66 kDa SBPs of embryonic stalk(*** ***)were cloned and identified using pMOSBlue vector.66 kDa(SBP)gene from the embryos of *** *** possesses 327 bp having an open reading frame(ORF)region in a part of the gene that encoded for 108 amino *** showed similarity among 66 kDa SBPs *** ***,with *** seed biotinylated protein(SBP65)and *** sbp65a mRNA with DNA distance matrix between 0.0094 to ***-TOF mass spectrometry analysis of 66 kDa(SBP)proteins showed it had similar short peptides to 19 proteins found in different organisms,especially Convicilin precursor,and the seed biotinylated protein in *** alignment results of both nucleotide sequences and amino acid residues either from cloning or MALDI-TOF-MS showed differences with related species,especially *** mRNA was found in the cotyledons during seeds germination,which means no metabolic activities and this part may act only as food reservoirs for growing newly embryos.

关键词： Cloning Embryo 66 kDa Pisum sativum Streptavidin-binding peptides(SBP)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Classification COVID-19 Based on Enhancement X-Ray Images and Low Complexity Model

引用

Computers, Materials & Continua 2022年第7期72卷 561-576页

作者： Aymen saad Israa SKamil ahmed Alsayat ahmed Elaraby Department of Information Technology Technical College of ManagementKufaAl Furat Alawsat UniversityIraq Department of Medical Laboratory Techniques Al-Mustaqbal University CollegeHillaIraq Department of Computer Science College of Computer and Information SciencesJouf UniversitySaudi Arabia Department of Computer Science Faculty of Computers and InformationSouth Valley UniversityQenaEgypt

COVID-19 has been considered one of the recent epidemics that occurred at the last of 2019 and the beginning of 2020 that world *** spread of COVID-19 requires a fast technique for diagnosis to make the appropriate decision for the treatment.X-ray images are one of the most classifiable images that are used widely in diagnosing patients’data depending on radiographs due to their structures and tissues that could be *** Neural Networks(CNN)is the most accurate classification technique used to diagnose COVID-19 because of the ability to use a different number of convolutional layers and its high classification *** using CNNs techniques requires a large number of images to learn and obtain satisfactory *** this paper,we used SqueezNet with a modified output layer to classify X-ray images into three groups:COVID-19,normal,and *** this study,we propose a deep learning method with enhance the features of X-ray images collected from Kaggle,Figshare to distinguish between COVID-19,Normal,and Pneumonia *** this regard,several techniques were used on the selected image samples which are Unsharp filter,Histogram equal,and Complement image to produce another view of the *** Squeeze Net CNN model has been tested in two scenarios using the 13,437 X-ray images that include 4479 for each type(COVID-19,Normal and Pneumonia).In the first scenario,the model has been tested without any enhancement on the *** achieved an accuracy of 91%.But,in the second scenario,the model was tested using the same previous images after being improved by several techniques and the performance was high at approximately 95%.The conclusion of this study is the used model gives higher accuracy results for enhanced images compared with the accuracy results for the original images.A comparison of the outcomes demonstrated the effectiveness of ourDLmethod for classifying COVID-19 based on enhanced X-ray images.

关键词： COVID-19 X-ray image enhancement classification CNN SqueezNet model

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oilfield produced water treatment in internal-loop airlift reactor using electrocoagulation/flotation technique

引用

Chinese Journal of Chemical Engineering 2018年第4期26卷 879-885页

作者： saad H.Ammar ahmed S.Akbar Department of Chemical engineering AL-Nahrain University

Oilfield produced water is large quantities of salty water trapped in underground formations and subsisted under high temperatures and pressures that are brought to the surface along with oil during production. Produced water(PW) contains a lot of pollutants such as hydrocarbons and metals, this water must be treated before disposal. Therefore, different techniques are being used to treat produced water. Electrocoagulation is an efficient treatment technique involving the dissolution of anodes and formation of electro-coagulants, while the simultaneous generation of H_2 bubbles at the cathode leads to the pollutant removal by flotation. Electrocoagulation(EC)method is one of the most promising and widely used processes to treat oilfield produced water. In the present work, a conventional internal-loop(draught tube) airlift reactor was utilized as electrocoagulation/flotation cell for PW treatment by inserting two aluminum electrodes in the riser section of the airlift reactor. The EC airlift reactor was operated in a batch mode for the liquid phase. Different experimental parameters were studied on the oil and turbidity removal efficiencies such as current density, initial pH, electrocoagulation time, and air *** experimental results showed that mixing of the oil droplets in the PW was accomplished using only the liquid recirculation resulted by H_2 microbubbles generated by EC process which enhanced the oil removal. The experimental results further showed that the EC time required achieving ≥ 90% oil removal efficiency decreases from 46 to 15 min when operating current density increases from 6.8 to 45.5 mA·cm^(-2). This reactor type was found to be highly efficient and less energy consuming compared to conventional existing electrochemical cells which used mechanical agitation.

关键词： Produced water Wastewater treatment Electrocoagulation/flotation Internal loop Airlift reactor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nature-inspired Hybrid Optimization Algorithms for Load Flow Analysis of Islanded Microgrids

引用

Journal of Modern Power Systems and Clean Energy 2020年第6期8卷 1250-1258页

作者： saad Mohammad Abdullah Ashik ahmed Quazi Nafees Ul Islam the Department of Electrical and Electronic Engineering Islamic University of TechnologyBoard BazarGazipur 1704Bangladesh

Load flow analysis is a significant tool for proper planning,operation,and dynamic analysis of a power system that provides the steady-state values of voltage magnitudes and angles at the fundamental ***,due to the absence of a slack bus in an islanded microgrid,modified load flow algorithms should be adopted considering the system frequency as one of the solution *** paper proposes the application of nature-inspired hybrid optimization algorithms for solving the load flow problem of islanded *** nature-inspired algorithms such as genetic algorithm(GA),differential evolution(DE),flower pollination algorithm(FPA),and grasshopper optimization algorithm(GOA)are separately merged with imperialistic competitive algorithm(ICA)to form four hybrid algorithms named as ICGA,ICDE,ICFPA,and *** of these algorithms are tested on the 6-bus test system and the modified IEEE 37-bus test system.A comparison among the proposed algorithms is carried out in terms of statistical analysis conducted using SPSS statistics *** the statistical analysis,it is identified that on an average,ICDE takes less number of iterations and consequently needs less execution time compared with other algorithms in solving the load flow problem of islanded microgrids.

关键词： Nature-inspired hybrid algorithm global optimization islanded microgrid load flow analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gene expression of 49 kDa apyrase,cytoskeletal proteins,ATPase,ADPase and amino acid contents of Pisum sativum(L.)cells germinated in Euryops arabicus(*** Jaub.&Spach)water extract

引用

BIOCELL 2019年第2期43卷 81-87页

作者： MAHMOUD MOUSTAFA saad ALAMRI HOIDA ZAKI NAGLAA LOUTFY TAREK TAHA ALI SHATI MOHAMED alkahtani SAJDA SIDDIQI Department of Biology College of ScienceKing Khalid University9004AbhaKingdom of Saudi Arabia(KSA) Department of Botany Faculty of ScienceSouth Valley UniversityQenaEgypt Environmental Biotechnology Department Genetic Engineering and Biotechnology Research Institute(GEBRI)City of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab City21934AlexandriaEgypt

The present research reports of quick and marked changes induced by plant extract of Euryops arabicus in the gene expression of 49-kDa apyrases,cytoskeletal proteins,ATPases,ADPase and amount of amino acid of pea(Pisum sativum ***).Pellets of cytoskeletals proteins(27000 xg)were probed with anti-apyrase antibody,biotinylated anti-rat,actin and alpha and beta-tubulin for Western *** and ADPase activities were determined based on the hydrolytic efficacy of adenine triphosphate and adenine *** 72 hours,the abundance of apyrases,cytoskeletal proteins and amount of amino acid in pellets of 27000 xg of germinated pea seeds in *** extracts were sharply increased than those sown in distilled *** the samples exhibited that the stems had more amount from apyrases,cytoskeletal proteins,amino acids and ATPase and ADPase activities than primary leaves and primary roots that were germinated either on *** water extract or in distilled *** on the enzyme’s capability to hydrolyse nucleotide triphosphate and nucleotide diphosphate as well as the direct association between expression of 49-kDa apyrase and cytoskeletal proteins,*** water extract had an important effect on plant germinations.

关键词： Cytoskeletal proteins ATPase ADPase Pisum sativum Euryops arabicus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Dynamical analysis and anti-synchronization of a new 6D model with self-excited attractors

引用

Applied Mathematics(A Journal of Chinese Universities) 2023年第1期38卷 27-43页

作者： saad Fawzi Al-Azzawi ahmed S.Al-Obeidi Department of Mathematics College of Computer Science and MathematicsUniversity of MosulMosul 41002Iraq

A novel 6D dissipative model with an unstable equilibrium point is introduced *** of the dynamic characteristics of the proposed model were explored via analyses and numerical simulations including critical points,stability,Lyapunov exponents,time phase portraits,and circuit ***,anti-synchronization phenomena were implemented on the new ***,the error dynamics is ***,four different controllers are adopted to stabilize this error relying on the nonlinear control technique with two main ways:linearization and Lyapunov stability *** comparison with previous works,the present controllers realize anti-synchronization based on another method/linearization ***,a comparison between the two ways was *** simulation results show the effectiveness and accuracy of the first analytical strategy.

关键词： 6D hyperchaotic system self-excited attractor anti-synchronization Lyapunov stability theory

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

风力发电机组运维数字孪生系统设计

引用

工程机械 2024年第5期55卷 1-4,I0012页

作者：杨嘉龙王国庆苏东鹏张旭东覃波石振宇 Ebrahim ahmed Hussein saad 长安大学工程机械学院

针对传统的风力发电机组运维管理存在被动运维、自动化程度低和劳动力需求高等问题,基于MBSE理论,提出建立风力发电机组运维数字孪生系统模型。介绍数字端模型构建过程,基于RPA流程自动化机器人技术的应用,以及基于风力发电机组运维管... 详细信息

针对传统的风力发电机组运维管理存在被动运维、自动化程度低和劳动力需求高等问题,基于MBSE理论,提出建立风力发电机组运维数字孪生系统模型。介绍数字端模型构建过程,基于RPA流程自动化机器人技术的应用,以及基于风力发电机组运维管理需求的运维系统引擎的设计方法,并开发了风力发电机组运维数字孪生系统原型软件。通过对风力发电机组运维数字孪生系统模型原型的开发,验证了建立风力发电机组运维数字孪生系统的可行性。

关键词： MBSE RPA 数字孪生仿真模型

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fusarium pseudograminearum and *** affect the root system architecture of bread wheat

引用

作物学报：英文版 2023年第1期11卷 316-321页

作者： ahmed saad Jack Christopher Anke Martin Stephen McDonald Cassandra Percy Centre for Crop Health University of Southern QueenslandToowoombaQLD 4350Australia University of Queensland Queensland Alliance for Agriculture and Food Innovation(QAAFI)Leslie Research FacilityToowoombaQLD 4350Australia

Yield losses of bread wheat due to crown rot can be more severe when drought conditions occur during the grain-filling *** architecture characteristics are important for soil exploration and belowground resource acquisition and are essential for adaptation to water-limited *** such as root angle,length and density have been strongly associated with acquisition efficiency and contribute to yield stability of the *** impact of crown rot pathogens on wheat root architecture is poorly *** examined differences in root angle,length and number,as well as dry root weight of the crown rot-susceptible bread wheat cultivar,Livingston inoculated with one of two crown rot pathogens Fusarium culmorum or Fusarium pseudograminearum in a transparent-sided root observation *** adverse impacts on plant health and growth were revealed by visual discolouration of the leaf sheaths;fresh and dry shoot weight;leaf area of the oldest and the youngest fully expanded leaf and leaf *** of most recorded root system measurements were reduced when inoculated with either *** or *** contrast,root angle was increased in the presence of *** but was not significantly changed by *** development of whiteheads and grain losses in bread wheat caused by crown rot have previously been associated with blockages of the vascular *** method employed here was able to identify differences in the pathogen impacts on roots,which were not detected using previous *** research indicates that in the presence of *** and *** infection,not only reductions in the size and biomass of the shoot system but also changes in the length,biomass and architecture of the root system could play an important role in yield loss.

关键词： Crown rot Root characteristics Livingston Wheat

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：