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Singly and Doubly Charged Projectile Fragments in Nucleus-Emulsion Collisions at Dubna Energy in the Framework of the Multi-Source Model

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Chinese Physics Letters 2011年第8期28卷 54-57页

作者： WANG Er-Qin LIU Fu-Hu Magda ARahim SFakhraddin sun jian-xin Institute of Theoretical Physics Shanxi UniversityTaiyuan 030006 Department of Physics Faculty of ScienceSana'a UniversityRepublic of Yemen School of Engineering Shanxi Datong UniversityDatong 037003

The multiplicity distributions of projectile fragments emitted in interactions of different nuclei with emulsion are studied by using a multi-source *** calculated results show that the projectile fragments can be described by the model and each source contributes an exponential *** the weighted sum of the folding result of many exponential distributions,a multi-component Erlang distribution is used to describe the experimental *** relationship between the height(or width)of the distribution and the mass of the incident projectile,as well as the dependence of projectile fragments on target groups,are investigated too.

关键词： exponential distribution Collisions

Pseudorapidity Distributions of Charged Particles and Contributions of Leading Nucleons in Cu-Cu Collisions at High Energies

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Chinese Physics Letters 2010年第3期27卷 108-111页

作者：孙建新刘福虎王二琴 Institute of Theoretical Physics Shanxi University Taiyuan 030006 School of Engineering Shanxi Datong University Datong 037003

The pseudorapidity distributions of charged particles produced in Cu-Cu collisions over an energy range from 22.4 GeV to 200 GeV are investigated by using a multi-source ideal gas model which contains systematically the contributions of leading nucleons. It is shown that the calculated results are in agreement with the experimental data and the model is successful in the description of the pseudorapidity distribution of charged particles. The contributions of leading nucleons increase with the increasing impact parameter. The cylinder length （the longitudinal shift of the interacting system） in rapidity space increases with the increasing energy and does not depend on centrality at a given energy.

关键词： Nuclear physics

Protective effect of paeoniflorin on H_(2)O_(2) induced Schwann cells injury based on network pharmacology and experimental validation

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Chinese Journal of Natural Medicines 2021年第2期19卷 90-99页

作者： ZHANG Di YANG Bing CHANG Shi-Quan MA Sheng-Suo sun jian-xin YI Lin LI xing SHI Hui-Mei JING Bei ZHENG Ya-Chun ZHANG Chun-Lan CHEN Feng-Guo ZHAO Guo-Ping College of Traditional Chinese Medicine Jinan UniversityGuangzhou 510630China LiWan Hospital of Traditional Chinese Medicine Guangzhou 510665China

This study was to investigate the protective effect of paeoniflorin(PF)on hydrogen peroxide-induced ***,“SMILES”of PF was searched in Pubchem and further was used for reverse molecular docking in Swiss Target Prediction database to obtain potential ***-related molecules were obtained from GeenCards database,and the predicted targets of PF for injury treatment were selected by Wayne *** mechanism analysis,the protein-protein interactions were constructed by String,and the KEGG analysis was conducted in ***,cell viability and cytotoxicity assay were established by CCK8 ***,the experimental cells were allocated to control,model(200μmol·L^(−1) H_(2)O_(2)),SB20358010μmol·L^(−1)(200μmol·L^(−1) H_(2)O_(2)+SB20358010μmol·L^(−1)),PF 50μmol·L^(−1)(200μmol·L^(−1) H_(2)O_(2)+PF 50μmol·L^(−1)),and PF 100μmol·L^(−1)(200μmol·L^(−1) H_(2)O_(2)+PF 100μmol·L^(−1))*** measured the intracellular ROS,Hoechst 33258 staining,cell apoptosis,the levels of Bcl-xl,Bcl-2,Caspase-3,Cleaved-caspase3,Cleaved-caspase7,TRPA1,TRPV1,and the phosphorylation expression of *** are 96 potential targets that may be associated with PF for injury ***,we chose the“Inflammatory mediator regulation of TRP channels”pathway for the experimental verification from the first 10 KEGG *** experimental verification,H_(2)O_(2) decreased the cell viability moderately(P<0.05),and 100μmol·L^(−1) PF increased the cell viability significantly(P<0.05).Depending on the difference of intracellular ROS fluorescence intensity,PF inhibited H_(2)O_(2)-induced reactive oxygen species production in Schwann *** Hoechst 33258 staining,PF reversed the condensed chromatin and apoptotic nuclei following H_(2)O_(2) ***,Flow cytometry results showed that PF could substantially inhibit H_(2)O_(2) induced apoptosis(P<0.05).Pretreatment with PF obviously reduced the levels of Caspase3,Cleaved-caspase3,Cleaved-caspase7,TRPA1,TRPV1,and the pho

关键词： Paeoniflorin Hydrogen peroxide H_(2)O_(2) p38MAPK Schwann cells Network pharmacology

Brain endothelial cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway in aging and neurodegeneration

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Neural Regeneration Research 2025年第7期20卷 2005-2007页

作者： Bryan sun Lulin Li jian Luo Palo Alto Veterans Institute for Research VA Palo Alto Health Care SystemPalo AltoCAUSA Polytrauma System of Care VA Palo Alto Health Care SystemPalo AltoCAUSA

The cyclic GMP-AMP synthase(cGAS)-stimulator of interferon genes(STING)signaling pathway has emerged as a key mediator of *** current studies primarily attribute its effects to neurons and glial cells,emerging research suggests that cGAS-STING signaling may play a critical role in cerebral vasculature,particularly in brain endothelial ***,studying the role 7of inflammation caused by the cGAS-STING pathway in brain endothelial cells could provide a more comprehensive understanding of neuroinflammatory disease and new avenues for therapeutic ***,we review the multifaceted role of global cGAS-STING signaling in various neurological and neuroinflammatory diseases and the potential contribution of cGAS-STING in brain endothelial cells.

关键词： stimulator interferon inflammation

CMIP5多模式集合对东北三省未来气候变化的预估研究

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地球物理学报 2016年第10期59卷 3580-3591页

作者：陶纯苇姜超孙建新北京林业大学林学院北京100083

应用CN05观测资料,以及参与国际耦合模式比较计划第5阶段(CMIP5)中的26个模式,评估了新一代全球气候模式对东北三省气候变化模拟能力并选出4个较优模式,发现经过筛选得出的较优模式集合平均模拟结果的可靠性得到进一步加强,尤其体现在... 详细信息

应用CN05观测资料,以及参与国际耦合模式比较计划第5阶段(CMIP5)中的26个模式,评估了新一代全球气候模式对东北三省气候变化模拟能力并选出4个较优模式,发现经过筛选得出的较优模式集合平均模拟结果的可靠性得到进一步加强,尤其体现在对气温的模拟上.在此基础上着重分析了多模式集合在不同典型浓度路径(RCPs)下对未来气候变化特征的预估.结果表明:21世纪的未来阶段,东北三省将处于显著增温的状态,且RCP8.5情景下的增温速率(0.53℃/10a)明显高于RCP4.5情景下的速率(0.22℃/10a);空间上,北部地区将成为增温幅度最大、增温速率最高的区域.未来降水将会相对增加,但波动较大,21世纪末期RCP4.5和RCP8.5情景下的降水增加幅度分别为11.24%和15.95%;空间上,辽宁省西部地区将成为降水增加最为显著的区域.根据水分盈亏量,21世纪未来阶段,RCP4.5情景下的东北三省绝大多数地区未来将相对变湿,尤其到了中后期;RCP8.5情景下则是中西部地区将相对变干,其余地区则会相对变湿.

关键词： CMIP5模式气候变化干旱预估中国东北三省

Inexact proximal gradient algorithm with random reshuffling for nonsmooth optimization

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Science China(Information Sciences) 2025年第1期68卷 219-237页

作者： Xia jianG Yanyan FANG Xianlin ZENG jian sun Jie CHEN National Key Lab of Autonomous Intelligent Unmanned Systems School of AutomationBeijing Institute of Technology Beijing Institute of Technology Chongqing Innovation Center School of Electronic and Information Engineering Tongji University

Proximal gradient algorithms are popularly implemented to achieve convex optimization with nonsmooth regularization. Obtaining the exact solution of the proximal operator for nonsmooth regularization is challenging because errors exist in the computation of the gradient; consequently, the design and application of inexact proximal gradient algorithms have attracted considerable attention from researchers. This paper proposes computationally efficient basic and inexact proximal gradient descent algorithms with random reshuffling. The proposed stochastic algorithms take randomly reshuffled data to perform successive gradient descents and implement only one proximal operator after all data pass through. We prove the convergence results of the proposed proximal gradient algorithms under the sampling-without-replacement reshuffling *** computational errors exist in gradients and proximal operations, the proposed inexact proximal gradient algorithms can converge to an optimal solution neighborhood. Finally, we apply the proposed algorithms to compressed sensing and compare their efficiency with some popular algorithms.

关键词： proximal operator random reshuffling inexact computation compressed sensing nonsmooth optimization

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席位分配公理的相容性与完备性

数学的实践与认识 2011年第4期41卷 78-84页

作者：孙建新浙江绍兴文理学院数学系浙江绍兴312000 浙江越秀外国语学院国际交流学院浙江绍兴312000

在原有的分配公理以外提出了若干新的公理,讨论了分配公理与数学模型之间的关系,然后给出极大相容公理组.

关键词：代表率分配率紧(宽)约束普适性无偏性极大相容公理组

微型法-珀腔阵列光谱探测器读出电路的模拟与设计

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传感技术学报 2008年第5期21卷 810-813页

作者：孙建新温志渝重庆大学光电技术及系统教育部重点实验室

针对微型法-珀腔阵列光谱探测器读出电路的单芯片集成化设计,在研究分析微型法-珀腔阵列光谱探测器的结构和工作原理的基础上,提出了基于2μm标准CMOS工艺的8位线阵微型法-珀腔阵列光谱探测器读出电路方案,研究了电路中各元器件的结构... 详细信息

针对微型法-珀腔阵列光谱探测器读出电路的单芯片集成化设计,在研究分析微型法-珀腔阵列光谱探测器的结构和工作原理的基础上,提出了基于2μm标准CMOS工艺的8位线阵微型法-珀腔阵列光谱探测器读出电路方案,研究了电路中各元器件的结构与结构参数,在ORCAD软件平台下完成了读出电路各单元电路与系统电路的设计、仿真与优化,利用TANNER软件完成了微型法-珀腔阵列光谱探测器读出电路的版图设计及版图验证。该电路工作电压为+5 V,总功耗为4.82μW,版图面积0.37 mm×0.22 mm。

关键词：光谱探测器读出电路 CMOS 版图法-珀腔

不完全信息动态博弈视角下的食品安全责任保险问题研究——基于参与主体之间的KMRW声誉博弈

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江西财经大学学报 2017年第2期 70-76页

作者：王康孙健周欣对外经济贸易大学保险学院北京100029

基于博弈论的视角,通过研究保险公司与食品企业之间的KMRW声誉博弈、保险公司尽职检查的博弈以及中介机构与食品企业串谋违规上报的博弈情况,分析食品安全责任保险运行过程中保险公司、中介机构与食品企业三者之间的博弈关系。结果表明... 详细信息

基于博弈论的视角,通过研究保险公司与食品企业之间的KMRW声誉博弈、保险公司尽职检查的博弈以及中介机构与食品企业串谋违规上报的博弈情况,分析食品安全责任保险运行过程中保险公司、中介机构与食品企业三者之间的博弈关系。结果表明:声誉缺失未能引起食品企业足够的重视且对维持声誉动力不足,进而导致食品的生产不能达到安全标准。保险公司应该建立声誉测量机制和奖惩机制,以达到对食品企业监督和约束的目的,同时能够使企业获得合理的利润。此外,保险公司还应建立中介机构的考核体系,降低中介机构的违规概率。

关键词：食品安全责任保险监管 KMRW声誉博弈