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IMPROVING SOLVER PERFORMANCE THROUGH REDUNDANCY

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Journal of Systems Science and Systems Engineering 2016年第3期25卷 303-325页

作者： Eduardo Lalla-ruiz Stefan Voβ Department of Computer Engineering and Systems University of La Laguna Spain Institute of Information Systems (IWI) University of Hamburg Germany Eseuela de Ingenierla Industrial Pontificia Universidad Catolica de Valparaiso (PUCV) Chile

It is well known that hierarchies of mathematical programming formulatlons with different numbers of variables and constraints have a considerable impact regarding the quality of solutions obtained once these formulations are fed to a commercial solver. In addition, even if dimensions are kept the same, changes in formulations may largely influence solvability and quality of results. This becomes evident especially if redundant constraints are used. We propose a related framework for information collection based on these constraints. We exemplify by means of a well-known combinatorial optimization problem from the knapsack problem family, i.e., the multidimensional multiple-choice knapsack problem （MMKP）. This incorporates a relationship of the MMKP to some generalized set partitioning problems. Moreover, we investigate an application in maritime shipping and logistics by means of the dynamic berth allocation problem （DBAP）, where optimal solutions are reached from the root node within the solver.

关键词： Erraticism redundant constraints multidimensional multiple-choice knapsack problem,dynamic berth allocation problem

Spectrum of esophageal motility disorders in patients with liver cirrhosis

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World Journal of Hepatology 2020年第12期12卷 1158-1167页

作者： Mohamed Khalaf Donald castell Puja Sukhwani Elias Department of Gastroenterology and Hepatology Medical University of South CarolinaCharlestonSC 29401United States Department of Internal Medicine Medical University of South CarolinaCharlestonSC 29425United States

Disorders of esophageal motility have been described in patients with cirrhosis in a small number of *** this review,we aim to provide an overview of the available evidence on esophageal motility disorders in cirrhosis and their clinical *** review delves into the following concepts:(1)Gastroesophageal reflux disease is common in liver cirrhosis due to many mechanisms;however,when symptomatic it is usually nocturnal and has an atypical presentation;(2)Endoscopic band ligation is better than sclerotherapy in terms of its effect on esophageal motility and seems to correct dysmotilities resulting from the mechanical effect of esophageal varices;(3)Chronic alcoholism has no major effects on esophageal motility activity other than lower esophageal sphincter hypertension among those with alcoholic autonomic neuropathy;(4)An association between primary biliary cholangitis and scleroderma can be present and esophageal hypomotility is not uncommon in this scenario;and(5)Cyclosporin-based immunosuppression in liver transplant patients can have a neurotoxic effect on the esophageal myenteric plexus leading to reversible achalasia-like manifestations.

关键词： Esophagus Motility Cirrhosis Dysmotility Gastroesophageal reflux disease Manometry

Cellular Auxin Homeostasis： Gatekeeping Is Housekeeping

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Molecular Plant 2012年第4期5卷 772-786页

作者： Michel ruiz Rosquete Department of Applied Genetics and Cell Biology University of Applied Life Sciences and Natural Resources (BOKU) 1190 Vienna Austria Department of Plant Systems Biology VIB and Department of Plant Biotechnology and Bioinformatics Ghent University 9052 Gent Belgium

The phytohormone auxin is essential for plant development and contributes to nearly every aspect of the plant life cycle. The spatio-temporal distribution of auxin depends on a complex interplay between auxin metabolism and cell-to-cell auxin transport. Auxin metabolism and transport are both crucial for plant development; however, it largely remains to be seen how these processes are integrated to ensure defined cellular auxin levels or even gradients within tissues or organs. In this review, we provide a glance at very diverse topics of auxin biology, such as biosynthesis, conjugation, oxidation, and transport of auxin. This broad, but certainly superficial, overview highlights the mutual importance of auxin metabolism and transport. Moreover, it allows pinpointing how auxin metabolism and transport get integrated to jointly regulate cellular auxin homeostasis. Even though these processes have been so far only separately studied, we assume that the phytohormonal crosstalk integrates and coordinates auxin metabolism and transport. Besides the integrative power of the global hormone signaling, we additionally introduce the hypothetical concept considering auxin transport components as gatekeepers for auxin responses.

关键词： auxin conjugation auxin homeostasis auxin metabolism auxin transport.

Relationship between surface area and crystal size of pure and doped cerium oxides

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Journal of Rare Earths 2010年第5期28卷 647-653页

作者： C. Bueno-Ferrer S. Parres-Esclapez D. Lozano-castelló A. Bueno-López Analytical Chemistry Nutrition & Food Sciences Department Inorganic Chemistry Department University of Alicante Ap. 99 E-03080 Alicante Spain

Pure and Zr, La or Pr-doped cerium oxides were characterised by transmission electron microscopy (TEM), N2 adsorption-desorption at –196 oC and X-ray diffraction (XRD). For crystal sizes calculation, the Scherrer and Williamson-Hall equations were compared, and the relationship between surface area and crystal size was critically discussed. It was demonstrated that the Williamson-Hall equation must be used instead of the Scherrer equation to calculate crystal sizes, since the latter equation underestimated ...

关键词： ceria XRD N2 adsorption crystal size surface area rare earths

Ecophysiology of egg rejection in hosts of avian brood parasites:new insights and perspectives

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Current Zoology 2021年第6期67卷 631-638页

作者： Francisco ruiz-RAYA Centro de Investigación Marina Universidade de VigoGEAVigo 36310Spain

Egg rejection is the most effective and widespread defense used by host species to counteract the extreme fitness costs frequently imposed by obligate avian brood ***,the proximate mechanisms underlying between-and within-individual variation in host responses remain poorly *** evidence suggests that egg rejection is dependent on individual physiological states,and draws attention to the role of hormones as mediators of flexible antiparasitic *** this perspective article,I outline recent advances in our understanding of the proximate factors that mediate egg rejection.I also point out some areas where knowledge remains still lacking,especially those related to the development and maintenance of effective cognitive functions,the potential role of oxidative stress,immunological state,and developmental stressors.I propose new hypotheses that stimulate future research on behavioral host responses toward brood parasitism.

关键词： cognitive performance condition-dependence corticosterone flexible responses prolactin

Analyzing the genomic and transcriptomic architecture of milk traits in Murciano-Granadina goats

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Journal of Animal Science and Biotechnology 2020年第3期11卷 649-666页

作者： Dailu Guan Vincenzo Landi María Gracia Luigi-Sierra Juan Vicente Delgado Xavier Such Anna castelló Betlem Cabrera Emilio Mármol-Sánchez Javier Fernández-Alvarez JoséLuis ruiz de la Torre Casañas Amparo Martínez Jordi Jordana Marcel Amills Centre for Research in Agricultural Genomics(CRAG) CSIC-IRTA-UAB-UBUniversitat Autònoma de Barcelona08193 BellaterraSpain Departamento de Genética Universidad de Córdoba14071 CórdobaSpain Departament de Ciència Animal i dels Aliments Facultat de VeterinàriaUniversitat Autònoma de Barcelona08193 BellaterraSpain Asociación Nacional de Criadores de Caprino de Raza Murciano-Granadina(CAPRIGRAN) 18340 GranadaSpain Servei de Granges i Camps Experimentals Universitat Autònoma de Barcelona08193 BellaterraSpain

Background:In this study,we aimed to investigate the molecular basis of lactation as well as to identify the genetic factors that influence milk yield and composition in *** achieve these two goals,we have analyzed how the mRNA profile of the mammary gland changes in seven Murciano-Granadina goats at each of three different time points,i.e.78 d(T1,early lactation),216 d(T2,late lactation)and 285 d(T3,dry period)after ***,we have performed a genome-wide association study(GWAS)for seven dairy traits recorded in the 1st lactation of 822 Murciano-Granadina ***:The expression profiles of the mammary gland in the early(T1)and late(T2)lactation were quite similar(42 differentially expressed genes),while strong transcriptomic differences(more than one thousand differentially expressed genes)were observed between the lactating(T1/T2)and non-lactating(T3)mammary glands.A large number of differentially expressed genes were involved in pathways related with the biosynthesis of amino acids,cholesterol,triglycerides and steroids as well as with glycerophospholipid metabolism,adipocytokine signaling,lipid binding,regulation of ion transmembrane transport,calcium ion binding,metalloendopeptidase activity and complement and coagulation *** regard to the second goal of the study,the performance of the GWAS allowed us to detect 24 quantitative trait loci(QTLs),including three genome-wide significant associations:QTL1(chromosome 2,130.72-131.01 Mb)for lactose percentage,QTL6(chromosome 6,78.90-93.48 Mb)for protein percentage and QTL17(chromosome 17,11.20 Mb)for both protein and dry matter ***,QTL6 shows positional coincidence with the casein genes,which encode 80%of milk ***:The abrogation of lactation involves dramatic changes in the expression of genes participating in a broad array of physiological processes such as protein,lipid and carbohydrate metabolism,calcium homeostasis,cell death and tissue remo

关键词： Casein genes Dairy traits GWAS Lactation QTLs RNA-Seq

Quantitative Analysis of Crime Incidents in Chicago Using Data Analytics Techniques

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Computers, Materials & Continua 2019年第5期59卷 389-396页

作者： Daniel Rivera ruiz Alisha Sawant Courant Institute of Mathematical Sciences New York University251 Mercer StNew York 10012USA

In this paper we aim to identify certain social factors that influence,and thus can be used to predict,the occurrence of *** factors under consideration for this analytic are social demographics such as age,sex,poverty,etc.,train ridership,traffic density and the number of business licenses per community area in Chicago,IL.A factor will be considered pertinent if there is high correlation between it and the number of crimes of a particular type in that community area.

关键词： Analytics big data Chicago correlation crime

In vitro germination and shoot proliferation of the threatened species Cinchona officinalis L(Rubiaceae).

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Journal of Forestry Research 2016年第6期27卷 1229-1236页

作者： Rosa Armijos-Gonzalez Cesar Perez-ruiz Departamento de Ciencias Naturales Universidad Tecnica Particular de LojaCP 1101 608 LojaEcuador Departamento de Biotecnologia y Biologia Vegetal E.T.S.Ingenieros AgronomosUniversidad Politecnica de MadridCP 728040 MadridSpain

Cinchona officinalis （Rubiaceae） is an endemic species of the Loja Valley in southern Ecuador with medicinal uses. Because of over-exploitation in the nine- teenth century and more recent disturbances to its ecosystem, C. officinalis populations are threatened. Currently, natural regeneration of the populations is low, despite its high plant regeneration and seed formation capacity. In the present study, an efficient protocol for germination, shoot proliferation and plantlets regeneration was developed for this species. Phenolic content and germination rate of C. officinalis seeds were compared with a control species, C. pubescens. Nodal segments from seedlings of C. officinalis were cultured on Gamborg medium supplemented with different combinations of plant growth regulators. Because the phenol content is high in C. officinalis, the phenolic should be removed with hydrogen peroxide or water washes to stimulate germination. Shoots and callus developed from nodal segments within 45 days using most of the tested combinations of plant growth regulators. The best rates of shoot proliferation, callus formation and adventitious buds were obtained in medium supplemented with 5.0 mg L^-1 6-benzyl-aminopurine and 3.0 mg L^-1 indole- 3-butyfic acid.

关键词： Callus Cinchona officinalis Germination Phenols Rubiaceae Shoot