检索结果-南通市图书馆

A SIMPLIFIED APPROACH TO EMBEDDING PROBLEMS IN NORMAL BORDISM FRAMEWORK

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Systems Science and Mathematical Sciences 1992年第2期5卷 180-192页

作者： LI Banghe LIU rong zhang ping (Institute of Systems Science,Academia Sinica,Beijing 100080,China)

The purpose of this paper is to simplify the computations of the nor-mal bordism groups Ωi（Wf,M×P∞;（?））and Ωi（Cf,（?）w;θf）which Salomonsenand Dax introduced respectively to study the existence and isotopy classificationof differential embeddings of manifolds in manifolds in the metastable *** space pair（Kf,M×P∞）is constructed to replace（Wf,M×P∞）.It isshown that（Kf,M×P∞）is homotopy equivalent to（Wf,M×P∞）and homotopy（n-1）-equivalent to（Cf,（?）W）.To demonstrate the efficacy of this simplification,the isotopy groups [Mn（?）RPn+k],if n（?）2k-4 and Mn is a closed（n-k+2）-connected manifold,and[Mn（?）L（p;q1…,qm）],if 3n（?）4m-2,Mn is a closed（2n-2m+1）-connected manifold and L is a （2m+1）-dimensional lens space,arespecifically computed.

关键词： Normal bordism group differential embedding isotopy

Three new diarylheptanoids and their antioxidant property

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2007年第10期18卷 1243-1246页

作者： Chang Xin Zhou Xiang Yi zhang Xiao Wu Dong Qiao Feng Tao Hui Dou rong ping zhang Ke Xin Huang Xiao Kun Li Chang Xiang Chen Su Zeng Yu Zhao College of Pharmaceutical Sciences Zhejiang University Hangzhou 310058 China College of Pharmacy Kunming College of Medicine Kunming 650031 China Pharmacy School of Wenzhou Medical College Wenzhou 325035 China Kunming Institute of Botany Chinese Academy of Sciences Kunming 650204 China

Three new diarylheptanoids, i.e., sodium（5S,2E）- 1,7-bis（4-hydroxyphenyl）- 1-hydroxy-2-hepten-5 -sulfonate （1）, sodium（5R,2E）-1,7-bis（4-hydroxyphenyl）-1-hydroxy-2-hepten-5-sulfonate （2） and 3,5-diacetoxy-1-（3-methoxy-4,5-dihydroxyphenyl）-7-（4-hydroxy-3-methoxyphenyl）heptane （3） were isolated from the rhizomes of Zingiber officinale. The structures of the new compounds were elucidated on the basis of spectroscopic methods. The antioxidant activities of 3 were assayed by in vitro models involving DPPH free radicals and superoxide anion radicals.

关键词： Diarylhcptanoid Zingiber officinale Antioxidant

Four new eremophilendiolides from Ligularia atroviolacea

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2007年第1期18卷 59-61页

作者： Shu Yun Shi Di Yao Wu Xun Gong Hua Peng rong ping zhang Chang Xin Zhou Xiao Jiang Hao Zhong Jian Jia Joachim Stockigt Yu Zhao Department of Traditional Chinese Medicine and Natural Drug Research College of Pharmaceutical Sciences Zhejiang University Hangzhou 310031 China College of Pharmacy Kunming College of Medicine Kunming China Kunming Institute of Botany Chinese Academy of Sciences Kunming 650204 China Lehrstuhl fiir Pharmazeutische Biologie lnstitut fur Pharmazie Johannes-Gutenberg Universitiit Mainz D-55099 Mainz Germany

From Ligularia atroviolacea, four new eremophilendiolides, 81$-hydroxy-eremophil-3,7 （11）-dien-12,8α（14,6α）-diolide （1）, 8β-methoxy-eremophil-3,7（11）-dien-12,8α（14,6α）-diolide （2）, 8α-hydroxy-eremophil-3,7（11）-dien-12,8lβ（14,6α）-diolide （3） and eremophil-3,7（11）,8-trien-12,8 （14,6α）-diolide （4）, as well as a known diolide （5） were isolated. Their structures were elucidated on the basis of 1D and 2D NMR as well as ESI-MS spectral data.

关键词： Phytochemical examination Sesquiterpene Eremophilendiolide Ligularia atroviolacea

Two new compounds from Zingiber officinale

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2007年第10期18卷 1247-1249页

作者： Yu Zhao Qiao Feng Tao rong ping zhang Chang Xin Zhou Hui Dou Shu Yun Shi Ye Cheng Xiao Lian Li Sun Su Zeng Ke Xin Huang Xiao Dong zhang Xiao Kun Li Department of Traditional Chinese Medicine and Natural Drug Research College of Pharmaceutical Sciences Zhejiang University Hangzhou 310058 China College of Pharmacy Kunming College of Medicine Kunming 650031 China Pharmacy School of Wenzhou Medical College Wenzhou 325035 China

A new cyclic diarylheptanoid, 1,5-epoxy-3-hydroxy-1-（3-methoxy-4,5-dihydroxyphenyl）-7-（4-hydroxyphenyl）-heptane （1）, as well as a new monoterpene, 10-O-β-n-glucopyranosyl-hydroxy cineole （2） were isolated from the rhizomes of Zingiber officinale. The structures of compounds 1 and 2 were established based on their spectral data. In addition, the antioxidant activities of these compounds were also measured.

关键词： Diarylheptanoid Monoterpene Zingiber officinale Antioxidant

Purification function of the natural wetland in the Liaohe Delta

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 1999年第2期11卷 109-115页

作者： Li Xiu Zhen, Qu Xiang rong, Wang Lian ping, zhang Hai rong, Xiao Du ning Institute of Applied Ecology, Chinese Academy of Sciences, B.O. Box 417, Shengyang 110015, China

The estuary wetland is the last barrier for inland pollutants flowing into the sea. The possibility to use the natural wetland, mainly reed marsh and Suaeda heteroptera community as land treatment system to polluted river water was studied. Experimental results indicated that the reed march has a high retention rate to pollutants like COD, N, P and oil. The canal system has high a purification rate to these elements as well. There is also a big potential to use the Suaeda community as a treatment system to exchange water from prawn and crab breeding ponds along the coast. As the pollution problem of coastal seawater has become more and more serious in Eastern China, and Liaohe is among the most seriously polluted 7 rivers in China, this study will greatly contribute to the strategy makers to take suitable reactions.

关键词： purification function wetland reed marsh canal Suaeda community.

A tree shrew model for steroid-associated osteonecrosis

在线全文

学校读者我要写书评

暂无评论

Zoological Research 2020年第5期41卷 564-568页

作者： Qi Chen Zhao-Xia Ma Li-Bin Xia Zhen-Ni Ye Bao-Ling Liu Tie-Kun Ma Peng-Fei Bao Xing-Fei Wu Cong-Tao Yu Dai-ping Ma Yuan-Yuan Han Wen-Guang Wang De-Xuan Kuang Jie-Jie Dai rong-ping zhang Min Hu Hong Shi Wen-Lin Wang Yan-Jiao Li Yunnan Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunmingYunnan 650500China Yunnan Key Laboratory for Basic Research on Bone and Joint Diseases&Yunnan Stem Cell Translational Research Center Kunming UniversityKunmingYunnan 650214China Department Obstetrics Second Affiliated Hospital of Kunming Medical UniversityKunmingYunnan 650101China Department of Nuclear Medicine First Affiliated Hospital of Kunming Medical UniversityKunmingYunnan 650031China Center of Tree Shrew Germplasm Resources Institute of Medical BiologyChinese Academy of Medical Sciences and Peking Union Medical CollegeKunmingYunnan 650118China School of Chinese Materia Medica Yunnan University of Chinese MedicineKunmingYunnan 650500China Kunming Medical University KunmingYunnan 650500China

DEAR EDITOR,Osteonecrosis is a common human disease in *** is difficult to treat,and half of patients may need artificial joint replacement,resulting in a considerable economic burden and a reduction in quality of *** are one of the major causes of osteonecrosis and high doses of corticosteroids are considered the most dangerous factor.

关键词： doses osteonecrosis artificial

岷江百合与兰州百合鳞茎中多酚组分及其生物活性

在线全文

学校读者我要写书评

暂无评论

食品工业科技 2018年第10期39卷 22-27,34页

作者：靳磊张瑞军雅蓉张萍宁夏大学农学院宁夏银川750021

为研究百合的抗氧化和抑菌活性,以野生岷江百合和兰州百合为材料,采用比色法、高效液相色谱法(HPLC)和比浊法对其鳞茎中总多酚、黄酮、黄烷醇、单体酚组分及含量、抗氧化能力和抑菌活性进行分析。结果表明:两种百合鳞茎中均富含多酚但... 详细信息

为研究百合的抗氧化和抑菌活性,以野生岷江百合和兰州百合为材料,采用比色法、高效液相色谱法(HPLC)和比浊法对其鳞茎中总多酚、黄酮、黄烷醇、单体酚组分及含量、抗氧化能力和抑菌活性进行分析。结果表明:两种百合鳞茎中均富含多酚但种间存在显著差异(p<0.05),岷江百合鳞茎中总多酚、黄酮和黄烷醇的含量分别是兰州百合含量的2.07、2.25、3.16倍;在两种百合鳞茎中检测出14种单体酚,其中原矢车菊素B2含量最高,在岷江百合和兰州百合中分别达到了37.60、20.60 mg·kg^(-1),除没食子酸外,岷江百合鳞茎中其他被检测出的单体酚含量是兰州百合的1.43~41.84倍;两种百合鳞茎多酚提取物均具有一定的抗氧化和抑菌活性,且岷江百合的抗氧化和抑菌活性均显著高于兰州百合(p<0.05),是兰州百合的1.40~14.40倍。野生岷江百合鳞茎多酚提取物具有抗氧化和抑菌双重作用,可作为天然抗氧化剂、抗菌药物应用于食品和医药业,具有良好的开发应用前景。

关键词：岷江百合多酚抗氧化能力抑菌活性

Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2955-2968页

作者： Wei zhang Yubao Lu Ruoqi Shen Yingjie Wu Chenrui Liu Xingxing Fang Liangming zhang Bin Liu Limin rong Department of Spine Surgery The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina National Medical Products Administration(NMPA)Key Laboratory for Quality Research and Evaluation of Cell Products GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Quality Control of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Engineering and Technology Research of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina

Microglia,the resident monocyte of the central nervous system,play a crucial role in the response to spinal cord ***,the precise mechanism remains *** investigate the molecular mechanisms by which microglia regulate the neuroinflammatory response to spinal cord injury,we performed single-cell RNA sequencing dataset analysis,focusing on changes in microglial *** found that the MG1 subpopulation emerged in the acute/subacute phase of spinal cord injury and expressed genes related to cell pyroptosis,sphingomyelin metabolism,and neuroinflammation at high ***,we established a mouse model of contusive injury and performed intrathecal injection of siRNA and molecular inhibitors to validate the role of ceramide synthase 5 in the neuroinflammatory responses and pyroptosis after spinal cord ***,we established a PC12-BV2 cell co-culture system and found that ceramide synthase 5 and pyroptosis-associated proteins were highly expressed to induce the apoptosis of neuron *** ceramide synthase 5 expression in a mouse model of spinal cord injury effectively reduced ***,ceramide synthase 5-induced pyroptosis was dependent on activation of the NLRP3 signaling *** ceramide synthase 5 expression in microglia in vivo reduced neuronal apoptosis and promoted recovery of neurological ***2g7 formed a“bridge”between sphingolipid metabolism and ceramide synthase 5-mediated cell death by inhibiting the NLRP3 signaling ***,these findings suggest that inhibiting ceramide synthase 5 expression in microglia after spinal cord injury effectively suppressed microglial pyroptosis mediated by NLRP3,thereby exerting neuroprotective effects.

关键词： ceramide synthase 5 gasdermin D microglia neuroinflammation NLRP3 nuclear factor kappa B Pla2g7 pyroptosis sphingomyelin metabolism spinal cord injury

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2025年第6期13卷 24-29页

作者： Wen-Jin Yuan Yi-Juan Zheng Bing-rong zhang Yi-Jie Lin You Li Yan-Yan Qiu Xue-ping Yu Department of Infection Disease Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian provinceFujian Medical University Affiliated First Quanzhou HospitalQuanzhou 362000Fujian ProvinceChina

BACKGROUND Hydroxyurea,an antimetabolite,is frequently prescribed for various hemato-logical disorders,and its common side effects include gastrointestinal problems,cutaneous or mucosal lesions and pyrexia/*** SUMMARY This study reports the case of a 67-year-old woman who developed recurrent abdominal pain after 10 years of continuous hydroxyurea therapy for primary *** revealed an ileocecal *** discontinuing hydroxyurea therapy for 6 months,follow-up colonoscopy showed a significant reduction in the *** We consider cecal ulcers as a rare complication of hydroxyurea therapy which typically resolves upon stopping the drug.

关键词： Hydroxyurea Ulcer Abdominal pain Thrombocythemia Colonoscopy Case report