Four new eremophilendiolides from Ligularia atroviolacea

作     者：Shu Yun Shi Di Yao Wu Xun Gong Hua Peng Rong Ping Zhang Chang Xin Zhou Xiao Jiang Hao Zhong Jian Jia Joachim Stockigt Yu Zhao 

作者机构：Department of Traditional Chinese Medicine and Natural Drug Research College of Pharmaceutical Sciences Zhejiang University Hangzhou 310031 China College of Pharmacy Kunming College of Medicine Kunming China Kunming Institute of Botany Chinese Academy of Sciences Kunming 650204 China Lehrstuhl fiir Pharmazeutische Biologie lnstitut fur Pharmazie Johannes-Gutenberg Universitiit Mainz D-55099 Mainz Germany 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2007年第18卷第1期

页      面：59-61页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 0703[理学-化学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：CSC3067 Zhejiang University,ZJU 

主　　题：Phytochemical examination Sesquiterpene Eremophilendiolide Ligularia atroviolacea 

摘      要：From Ligularia atroviolacea, four new eremophilendiolides, 81$-hydroxy-eremophil-3,7 （11）-dien-12,8α（14,6α）-diolide （1）, 8β-methoxy-eremophil-3,7（11）-dien-12,8α（14,6α）-diolide （2）, 8α-hydroxy-eremophil-3,7（11）-dien-12,8lβ（14,6α）-diolide （3） and eremophil-3,7（11）,8-trien-12,8 （14,6α）-diolide （4）, as well as a known diolide （5） were isolated. Their structures were elucidated on the basis of 1D and 2D NMR as well as ESI-MS spectral data.