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Acta Mathematica Scientia 2013年第5期33卷 1275-1292页

作者： rogerio Luiz Quintino de OLIVEIRA JUNIOR Instituto de Matema'tica e Estat' stica Universidade do Estado do R.de Janeiro Rua S ao Francisco Xavier524 - Pavilha o Reitor Joa o Lyra Filho 6oandar bl.B 20559-900 Rio de Janeiro R.J. Brazil

In this paper, we study the large time behavior of solutions of the parabolic semilinear equation δtu-div（a（x）△↓u） = -｜u｜^αu in （0,∞） × R^N, where α 〉 0 is constant and a∈ Cb^1（R^N） is a symmetric periodic matrix satisfying some ellipticity *** an integrable initial data u0 and α ∈ （2/N, 3/N）, we prove that the large time behavior of solutions is given by the solution U（t, x） of the homogenized linear problem δtU-div（a^h△↓U）=0,U（0） = C, where a^h is the homogenized matrix of a（x）, C is a positive constant and δ is the Dirac measure at 0.

关键词： homogenization similinear parabolic equation integrable initial data matrix with periodic coefficient large time behavior

Saturated anisotropic hydraulic conductivity of a compacted lateritic soil

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Journal of Rock Mechanics and Geotechnical Engineering 2018年第5期10卷 986-991页

作者： Roberto Aguiar dos Santos Edmundo rogerio Esquivel Varzea Grande Institute of Engineering Federal University of Mato Grosso Cuiaba Mato Grosso Brazil Sao Carlos School of Engineering University of Sao Paulo Sao Carlos Sao Paulo Brazil

This study focuses on the saturated anisotropic hydraulic conductivity of a compacted lateritic clayey sandy soil. The effects of the molding water content and the confining stress on the anisotropic hydraulic conductivity are investigated. The hydraulic conductivity is measured with a flexible-wall permeameter. Samples are dynamically compacted into the three compaction states of a standard Proctor compaction curve： the dry branch, optimum water content and wet branch. Depending on the molding water content and confining stress, the hydraulic conductivity may increase or decrease. In addition, the results indicate that, when the samples are compacted to the optimum water content, lower hydraulic conductivity is obtained, except at a confining stress equal to 50 kPa. The increase of the confining stress decreases the hydraulic conductivity for each of the evaluated compaction states. In the wet branch, horizontal hy- draulic conductivity is about 8 times higher than the vertical value. The anisotropic hydraulic conduc- tivities of the dry and wet branches decrease when the confining stress increases, and the opposite is observed in the optimum water content state.

关键词： Hydraulic conductivity Anisotropic behavior Lateritic soil Tropical soil Compacted soil

Molecular characterization of an extensively drug-resistant Acinetobacter baumannii isolated from a corn culture soil

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Pedosphere 2021年第6期31卷 973-976页

作者： Joao Pedro Rueda furlan Eliana Guedes STEHLING Departamento de Analises Clinicas Toxicologicas e BromatologicasFaculdade de CienciasFarmaceuticas de Ribeirao PretoUniversidade de Sao Paulo(USP)Ribeirao Preto SP 14040-903(Brazil)

Dear Editor,Soil is the most biodiverse habitat on Earth and it has been estimated that one gram of soil can contain up to one billion bacterial cells(Fierer,2017).The microorganisms of soil produce a wide variety of ... 详细信息

关键词： soil corn culture

Genomic characterization of multidrug-resistant extraintestinal pathogenic Escherichia coli isolated from grain culture soils

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Pedosphere 2022年第3期32卷 495-502页

作者： João Pedro Rueda furlan Inara Fernanda Lage GALLO Eliana Guedes STEHLING Departamento de Análises Clínicas Toxicológicas e BromatológicasFaculdade de Ciências Farmacêuticas de Ribeirão PretoUniversidade de São PauloRibeirão PretoSão Paulo 14040-903(Brazil)

Multidrug-resistant(MDR)Escherichia coli,mainly extraintestinal pathogenic ***(ExPEC),has been widely reported in infections *** agricultural soils,manure is a hotspot for the dissemination of antimicrobial resistance genes(ARGs)and pathogenic bacteria;however,MDR bacteria have also been reported in soils with no history of manure *** addition,cross-resistance and co-resistance have been described as responsible for the metal-driven selection of bacteria resistant to ***,the aim of this study was to analyze three MDR *** isolates obtained from Brazilian grain culture soil samples with no history of manure use by whole-genome *** MDR *** isolates were recovered from soils from corn and coffee fields,and presented resistance toβ-lactams,quinolones,aminoglycosides,tetracyclines,sulphonamides,and dihydrofolate reductase *** analysis showed ARGs to several antimicrobials(i.e.,β-lactams,tetracyclines,aminoglycosides,sulphonamides,trimethoprim,phenicols,fosfomycin,and macrolides)as well as several metal resistance genes and antibacterial biocide resistance *** addition,known mutations in quinolone-resistance-determining regions of GyrA(Ser83Leu and Asp87Asn),ParE(Ser458Thr),and ParC(Ser80Ile)were also *** analysis showed the presence of virulence genes(lpfA,mcmA,gad,mchF,iroN,cma,and iss)associated with ***-resistant ExPEC isolates were assigned to phylogenetic group *** presence of MDR B1-ExPEC in soil samples shows the ability of these isolates to survive in *** study reports for the first time some sequence types(i.e.,ST345,ST448,and ST1146)of MDR *** in Brazilian ***,these findings contribute to the monitoring of antimicrobial resistance and surveillance studies based on whole-genome sequencing worldwide.

关键词： antimicrobial resistance gene metal resistance gene molecular typing whole-genome sequencing

Tapir health and conservation medicine

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Integrative Zoology 2012年第4期7卷 331-345页

作者： Paulo rogerio MANGINI Emilia Patrícia MEDICI Renata Carolina FERNANDES-SANTOS Lowland Tapir Conservation Initiative IPÊ-Institute for Ecological ResearchNazaréPaulistaSão PauloBrazil Brazilian Institute for Conservation Medicine-TRÍADE RecifePernambucoBrazil IUCN/SSC Tapir Specialist Group(TSG) GlandSwitzerland IUCN/SSC Wildlife Health Specialist Group(WHSG) New YorkNYUSA IUCN/SSC Peccary Specialist Group(PSG) GlandSwitzerland Escola Superior de Conservação Ambiental e Sustentabilidade(ESCAS/IPÊ) NazaréPaulistaSão PauloBrazil IUCN/SSC Conservation Breeding Specialist Group(CBSG) Brazil NetworkCampo GrandeBrazil

Tapirs have unique nutritional needs,as well as anatomical,physiological,behavioral and ecological adapta-tions that must be considered when managing their health,both in the wild and in *** about how tapirs live in their natural habitats can provide crucial knowledge to prevent many of the health problems found in captivity such as infectious and parasitic diseases,reproductive issues and nutritional and behavior-al ***,proper management in captivity can significantly contribute to in situ conservation *** medicine is a science created to address the global health crisis that jeopardizes biodiver-sity causing imbalances among ecosystem,human,animal and vegetal *** this context,common threats to tapir health and conservation,such as isolated and small populations surrounded by human activity,chemical pollution,domestic animals and their pathogenic agents,need to be better *** manuscript provides information about the health of tapirs both in captivity and in the wild and aims to encourage tapir conservation-ists worldwide to gather information about pathogen and disease dynamics and manifestation,as well as impli-cations for tapir conservation.

关键词： captive management conservation medicine tapirs wildlife health

Insights into the Effect of a Natural Arsenate Dose on Growth,Nodulation and Redox Metabolism of Soybean Plants

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Pedosphere 2019年第4期29卷 527-533页

作者： Eliana BIANUCCI Ana furlan Luis E.HERNáNDEZ Stella CASTRO Instituto de Investigaciones Agrobiotecnológicas INIAB CONICET-UNRC Facultad de Ciencias ExactasFísico-Químicas y Naturales Universidad Nacional de Río Cuarto Laboratorio de Fisiología Vegetal Departamento de BiologíaUniversidad Autónoma de Madrid

Dear Editor, Arsenic (As) is a harmful metalloid that occurs in soil and water;its concentration varies considerably among geographic regions, with groundwater being the principal source of human contamination (Smedley and Kinniburgh, 2002). Besides the direct contamination effect of drinking water that contains high As concentration, human poisoning may also occur after ingestion of contaminated food.

关键词： Natural Arsenate Soybean Plants Redox Metabolism

Risk factors, surgical complications and graft survival in liver transplant recipients with early allograft dysfunction

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Hepatobiliary & Pancreatic Diseases International 2019年第5期18卷 423-429页

作者： Douglas Bastos-Neves Paolo rogerio de Oliveira Salvalaggio Marcio Dias de Almeida Digestive and Hepatobiliary Surgery Hospital Sao Vicente de PauloRio de JaneiroBrazil Liver Transplant Unit Hospital Israelita Albert EinsteinSao PauloBrazil

Background: Early allograft dysfunction (EAD) is a severe complication after liver transplantation. The associated risk factors and complications have re-gained recent interest. This study investigated risk factors, survival and complications associated with EAD in a large liver transplant center in Latin America. Methods: Retrospective, unicenter, cohort, based on data from adult patients undergoing first deceaseddonor liver transplant from January 2009 to December 2013. EAD was defined by one or more of the following:(i) bilirubin ≥10 mg/dL on postoperative day 7;(ii) international normalized ratio ≥1.6 on postoperative day 7, and (iii) alanine aminotransferase or aspartate aminotransferase > 2000 IU/L within the first seven days after transplant. Results: A total of 602 patients were included;of these 34.2% developed EAD. Donor risk factors were male ( P = 0.007), age between 50 and 59 years ( P = 0.034), overweight ( P = 0.028) or grade I obesity ( P = 0.012), sodium > 157 mmol/L ( P = 0.002) and grade IV ischemia/reperfusion injury ( P = 0.002). Cold ischemia time ≥10 h ( P = 0.008) and warm ischemia time ≥40 min ( P = 0.013) were the surgical factors. Male ( P 157 mmol/L and grade Ⅳ ischemia/reperfusion injury. Cold ischemia time ≥10 h and warm ischemia time ≥40 min were the surgical risk factors. Male was the only recipient protective factor. Patients with EAD had higher reoperations and graft loss rates.

关键词： Graft survival Liver transplantation Primary graft dysfunction Donor evaluation

Modern surgical strategies for perianal Crohn's disease

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World Journal of Gastroenterology 2020年第42期26卷 6572-6581页

作者： Gilmara Pandolfo Zabot Ornella Cassol rogerio Saad-Hossne Willem Bemelman Department of Coloproctology Hospital Moinhos de VentoPorto Alegre 90035-902RSBrazil Department of Surgery Hospital de Clínicas de Passo FundoPasso Fundo 99010-260RSBrazil Department of Internal Medicine São Paulo State University(Unesp)Medical SchoolBotucatu 18618687São PauloBrazil Department of Surgery Amsterdam University Medical CenterUniversity of AmsterdamAmsterdam 19268Netherlands

One of the most challenging phenotypes of Crohn’s disease is perianal fistulizing disease(PFCD).It occurs in up to 50%of the patients who also have symptoms in other parts of the gastrointestinal tract,and in 5%of the cases it occurs as the first *** is associated with severe symptoms,such as pain,fecal incontinence,and a significant reduction in quality of *** presence of perianal disease in conjunction with Crohn’s disease portends a significantly worse disease *** patients require close monitoring to identify those at risk of worsening disease,suboptimal biological drug levels,and signs of developing *** last 2 decades have seen significant advancements in the management of *** recently,newer biologics,cell-based therapies,and novel surgical techniques have been introduced in the hope of improved ***,in refractory cases,many patients face the decision of having a stoma made and/or a proctectomy *** this review,we describe modern surgical management and the most recent advances in the management of complex PFCD,which will likely impact clinical practice.

关键词： Crohn’s disease Inflammatory bowel disease Surgical treatment Perianal fistulas Anorectal fistula

Epidemiology of inflammatory bowel diseases in the state of Rio Grande do Sul,Brazil

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World Journal of Gastroenterology 2022年第30期28卷 4174-4181页

作者： Ornella Sari Cassol Gilmara Pandolfo Zabot rogerio Saad-Hossne Alexandre Padoin Department of Coloproctology IMED Medical SchoolPasso Fundo 99010260RSBrazil Graduate Program in Medicine and Health Sciences Pontifícia Universidade Católica do Rio Grande do Sul(PUCRS)Porto Alegre 90610001RSBrazil Department of Coloproctology Coloprocto Canoas ClinicCanoas 92310205RSBrazil Department of Coloproctology Hospital Moinhos de Vento(HMV)Porto Alegre 90035000RSBrazil Department of Surgery and Orthopaedics Universidade Estadual Paulista(UNESP)Botucatu 18618687SPBrazil

BACKGROUND This is the first study on the epidemiology of inflammatory bowel diseases(IBDs)in Rio Grande do Sul(RS),the southernmost state of Brazil with the country’s fifth largest ***’s disease(CD)and ulcerative colitis(UC)are collectively termed *** have high incidence and prevalence rates in highincome countries,although in recent years there has been a change in the classic geographical distribution of IBDs,with growing rates in traditionally lowincidence *** To estimate the incidence and prevalence of IBDs in the RS state,Brazil,between 2014 and *** This is a cross-sectional descriptive observational *** with IBD who had initiated treatment and met the inclusion criteria of the RS state free drug distribution program were *** were obtained from registration or renewal records of the RS state specialty *** male,female,and total populations were estimated according to mid-year data from the Brazilian Institute of Geography and Statistics,which served as a reference for calculating the incidence and prevalence rates of IBDs during the study *** were described using mean,standard deviation,and *** We included 1082 patients with IBD,of whom 57.5%were female and 42.5% were *** with CD accounted for 72.45% of the sample,and those with UC accounted for 27.54%.IBD prevalence during the study period was 9.51 per 100000 population,of which 6.89 corresponded to people with CD and 2.62,to people with *** rates per 100000 population/year were 2.54 in 2014,2.61 in 2015,1.91 in 2016,0.80 in 2017,0.83 in 2018,and 0.96 in *** mean IBD incidence rate per 100000 population was 1.61,of which 1.17 corresponded to CD and 0.44,to *** mean age was 41 years,and patients were mostly aged 30-40 *** by region was higher in the state capital metropolitan area:12.69 per 100000 *** Our results demonstrated an IBD prevalence of 9.51% and incidence of

关键词： Inflammatory bowel diseases Crohn’s disease Ulcerative colitis Epidemiology Incidence Prevalence