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Journal of Clinical and Translational Hepatology 2018年第4期6卷 362-371页

作者： Daniel Bodek Pavan Patel Sushil Ahlawat evan Orosz Thayer Nasereddin Nikolaos Pyrsopoulos Rutgers New Jersey Medical School University HospitalNewarkNJUSA

Background and Aims:Hepatic encephalopathy is a liver disease complication with significant mortality and *** aim of this study was to evaluate the relative performance of facilities based on their teaching status and transplant capability by correlating their connections to mortality,cost,and length of stay from 2007 to ***:The Nationwide Inpatient Sample database was utilized to collect information on(USA)American patients admitted with a primary diagnosis of hepatic encephalopathy from *** were placed into one of four categories using their teaching and transplant *** regression analysis,mortality,length of stay and cost adjusted rate ratios were ***:The study revealed that teaching transplant centers had a mortality risk ratio of 0.783(95%confidence interval(CI):0.750-0.819,p<0.001).Blacks had the highest mortality risk ratio,of 1.273(95%CI:1.217-1.331,p<0.001).Furthermore,teaching transplant hospitals had a cost rate ratio of 1.226(95%CI:1.214-1.238,p<0.001)and a length of stay rate ratio of 1.104(95%CI:1.093-1.115,p<0.001).Conclusions:It appears that admission to transplant facilities for hepatic encephalopathy is associated with reduced mortality but increased costs and longer stay independent of ***,factors impacting black mortality should also be examined more closely.

关键词： Disparities Mortality Cost Length of stay Hepatic encephalopathy

Piperine,an active ingredient of black pepper attenuates acetaminophen-induced hepatotoxicity in mice

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Asian Pacific Journal of Tropical Medicine 2010年第12期3卷 971-976页

作者： evan Prince Sabina Annie Deborah Harris Souriyan Deborah Jackline Mahaboob Khan Rasool School of Biological Sciences and Technology VIT University Vellore - 632 014Tamil NaduIndia

Objective:To explore the hepatoprotective and antioxidant effects of piperine against acetaminophen-induced hepatotoxicity in ***:In mice,hepatotoxicity was induced by a single dose of acetaminophen(900 mg/kg b.w.i.p.).Piperine(25 mg/kg b.w.i.p.) and standard drug silymarin(25 mg/kg b.w.i.p.) were given to mice,30 min after the single injection of *** 4 h,the mice were *** of liver marker enzymes [(aspartate transaminase(AST),alanine transaminase(ALT),and alkaline phosphatase(ALP)]and inflammatory mediator tumour necrosis factor-alpha(TNF-α) were estimated in serum,while lipid peroxidation and antioxidant status(superoxide dismutase,catalase,glutathione peroxidase, glutathione reductase,glutathione-s-transferase and glutathione) were determined in liver homogenate of control and experimental ***:Acetaminophen induction(900 mg/kg b.w.i.p.) significantly increased the levels of liver marker enzymes,TNF-α,and lipid peroxidation,and caused the depletion of antioxidant *** and silymarin treatment to acetaminophen challenged mice resulted in decreased liver marker enzymes activity,TNF-αand lipid peroxidation levels with increase in antioxidant ***:The results clearly demonstrate that piperine shows promising hepatoprotective effect as comparable to standard drug silymarin.

关键词： Pipeline Hepatoprotective Antioxidant enzymes Lipid peroxidation TNF-α

Development of a multivariate empirical model for predicting weak rock mass modulus

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International Journal of Mining Science and Technology 2015年第4期25卷 545-552页

作者： Kallu Raj R. Keffeler evan R. Watters Robert J. Agharazi Alireza Department of Mining Engineering University of Nevada RESPEC Consulting and Services University of Nevada Itasca Houston Inc.

Estimating weak rock mass modulus has historically proven difficult although this mechanical property is an important input to many types of geotechnical analyses. An empirical database of weak rock mass modulus with associated detailed geotechnical parameters was assembled from plate loading tests per- formed at underground mines in Nevada, the Bakhtiary Dam project, and Portugues Dam project. The database was used to assess the accuracy of published single-variate models and to develop a multivari- ate model for predicting in-situ weak rock mass modulus when limited geoteehnical data are available. Only two of the published models were adequate for predicting modulus of weak rock masses over lim- ited ranges of alteration intensities, and none of the models provided good estimates of modulus over a range of geotechnical properties. In light of this shortcoming, a multivariate model was developed from the weak rock mass modulus dataset, and the new model is exponential in form and has the following independent variables：（1） average block size or joint spacing, （2） field estimated rock strength, （3） dis- continuity roughness, and （4） discontinuity infilling hardness. The multivariate model provided better estimates of modulus for both hard-blocky rock masses and intensely-altered rock masses.

关键词： In-situ modulus Weak rock mass Preliminary design Elastic deformation

Genetic variation and potential coinfection of Wolbachia among widespread Asian citrus psyllid (Diaphorina citri Kuwayama) populations

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Insect Science 2019年第4期26卷 671-682页

作者： Chia-Ching Chu Mark Hoffmann W. evan Braswell Kirsten S. Pelz-Stelinski Department of Entomology and Nematology University of Florida Gainesville Florida USA Citrus Research and Education Center University of Florida Lake Alfred Florida USA 3Department of Horticultural Sciences North Carolina State University Raleigh North Carolina USA Center for Plant Health Science and Technology USDA APHIS Edinburg Texas USA

Wolbachia can profoundly influence the survival, reproduction, and defenses of insect hosts. These interactions could potentially be harnessed for managing pests or insecttransmitted diseases. Diaphorina citri Kuwayama is a phloem-feeding pest capable of transmitting the putative causal agent of citrus greening, Candidatus Liberibacter asiaticus (CLas). Like many insects, D. citri is also infected with Wolbachia (wDi). Recent studies indicate that the relative abundance of wDi could be associated with the abundance of CLas, and that wDi may contribute to regulating expression of phage lytic cycle genes in CLas, suggesting the need for better understanding of wDi biology in general. This study investigated the genetic diversity of wDi among D. citri in populations spanning eleven countries and two U.S. territories. Six Wolbachia genes, wsp, ***, gatB, and hep A, were sequenced and compared across samples. Two prevalent wDi strains were identified across the samples, and screening of clone libraries revealed possible coinfection of wDi strains in specific populations. D. citri mitochondrial cytochrome oxidase subunit I gene (mtCOI) were more divergent between D. citri populations that were infected with different wDi strains or had different infection statuses (single infection vs. coinfection). While we could not eliminate the possibility that maternal transmission may contribute to such patterns, it is also possible that wDi may induce cytoplasmic incompatibility in their host. These fin dings should contribute to the understanding of wDi population ecology, which may facilitate manipulation of this endosymbiont for management of citrus greening disease worldwide.

关键词： bacteria genetic diversity Huanglongbing plant disease superinfection vertically transmitted endosymbionts

A Hunter-Gatherer Exercise Prescription to Optimize Health and Well-Being in the Modern World

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Journal of Science in Sport and Exercise 2021年第2期3卷 147-157页

作者： evan L.O’Keefe Carl J.Lavie Ochsner Clinical School The University of Queensland School of MedicineNew OrleansLAUSA Department of Cardiovascular Diseases John Ochsner Heart and Vascular Institute1514 Jefferson HighwayNew OrleansLA 70121-2483USA

There has been considerable innovation and advancement in the field of exercise and physical activity (PA).In regards to the battle against chronic non-communicable disease,however,we believe the model of PA that would prove most salu-tary is one closely mimicking that of our hunter-gatherer *** the purpose of longevity,the human body and our genetic makeup have been evolutionarily adapted to respond best to moderate amounts of high-intensity interval training,in conjunction with high amounts of low intensity ***,to optimize resiliency and cardiorespiratory fitness,a hunter-gatherer fitness regimen must include cross training targeted at flexibility,balance and *** not com-monly understood,the health benefits from exercise comprise a reverse *** endurance athletes residing on the furthest reaches of the PA spectrum appear to lose a substantial portion of the exercise-related longevity and cardiovascular benefits due to cardiac overuse ***,there is an emerging body of evidence suggesting leisure time exercise done with peers in a natural environment is significantly superior to that training done in *** idea of the "power of play" lends support to the ancestral model of PA whereby humans are evolutionary adapted to be highly social,outdoor creatures capable of a diverse range of PA at varying intensities.

关键词： Hunter-gatherer Cardiovascular disease Physical activity Exercise

Physical Properties of SiC Nanostructure for Optoelectronics Applications

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Journal of Renewable Materials 2021年第9期9卷 1519-1530页

作者： Mayyadah H.Mohsin Najwan H.Numan evan T.Salim Makram A.Fakhri Applied Science Department University of Technology-IraqBaghdad10066Iraq Laser and Optoelectronic Engineering Department University of Technology-IraqBaghdad10066Iraq

A SiC nanofilms have been deposited and investigated on quartz and silicon substrates using pulsed laser deposition technique with the 300 pulses of Nd:YAG laser at two different laser wavelengths of 1064 nm and 532 *** structural,morphological,and optical properties of the deposited nanostructure SiC were prepared and characterized as a function of the wavelengths of the used *** structural result shows four different pecks at(111),(200),(220),and(311)planes related to Nano *** transmission result presents that the optical energy gap value for the SiC nanostructure is depended on the wavelength of the used laser and it is found about the range(3.03 eV–3.23 eV).The investigations of the SEM and AFM show that the prepared SiC Nano-films having a grain size range(36.34–48.75)nm and roughness about 4.462 to 3.062 ***/Si hetero-junction devices show an enhanced performance at 532 nm.

关键词： Pulsed Laser deposition nanostructure 4H-SiC PLD heterostructure nanofilms

Trauma systems in Canada:striving for quality across an expansive landmass

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Emergency and Critical Care Medicine 2023年第3期3卷 89-93页

作者： Natasha G.Caminsky evan G.Wong Division of General and Trauma Surgery McGill UniversityMontrealQuebecCanada

Although Canada has a universal health care program that provides free in-hospital services to all citizens,its vast landmass and nonstandardized prehospital and posthospital systems make delivering quality trauma care challenging,particularly to resource-limited rural *** article summarizes the strengths of the prehospital system,facility-based care,trauma network,trauma registry,rehabilitation,and governance/financing/quality assurance components of Canada’s trauma *** directions,including the use of telemedicine,standardization of practices,and resource optimization,are also ***’s trauma system is well developed,yet geography impedes equitable *** standardization and resource optimization are needed.

关键词： Trauma referral Trauma registry Trauma systems Universal health care

Effect of pumping chamber on performance of non-overload centrifugal pump

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Journal of Central South University 2015年第8期22卷 2989-2997页

作者：谷云庆牟介刚代东顺郑水华吴登昊蒋兰芳施瀚昱 WANG evan College of Mechanical and Engineering Zhejiang University of Technology Engineering Research Center of Process Equipment and Its Re-manufacturing of Ministry of Education(Zhejiang University of Technology) Zhijiang College Zhejiang University of Technology Institut National Polytechnique of Grenoble Joseph Fourier University

In order to specify the characteristics of un-overloaded centrifugal pumps, the IH100-65-200 pump was chosen as the model pump. Different calculation models for centrifugal pumps were established under different pumping chamber sectional parameters. In the numerical simulation of the centrifugal pumps flow field, the shaft power, head, efficiency, and the changes of the internal flow field under different sectional areas and sectional shapes were studied with the RNG k-ε turbulence model, and the influence of the pumping chamber section characteristics of the non-overloaded centrifugal pumps were analyzed. The results show that sectional areas have a significant impact on the non-overload characteristics of centrifugal pumps. The shaft power and head of centrifugal pump are increasing with a lager sectional area, by which the gradient of head curves decreases. The efficiency is improved under a large flow rate condition, but the head and the efficiency are reduced at a small flow rate. It is also observed that the sectional shapes have less influence on the shaft power, the hydraulic performance and flow field characteristics of a centrifugal pump.

关键词： centrifugal pumps sectional area sectional shape non-overload characteristics numerical simulation

A plant-based diet and heart failure： case report and literature review

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Journal of Geriatric Cardiology 2017年第5期14卷 375-378页

作者： evan Y Choi Kathleen Allen Michael McDonnough Daniele Massera Robert J Ostfeld Department of Medicine Montefiore Medical Center Bronx NY USA Department of Nutrition & Food Studies New York University NY NY USA Department of Nutrition New York-Presbyterian Hospital NY NY USA Division of Cardiology Montefiore Medical Center Bronx NY USA

Heart failure is associated with high rates of morbidityand mortality, and is a burden to the healthcare *** is a growing appreciation for the role diet may play inthe development and treatment of heart failure.

关键词： Heart failure Lifestyle Plant-based diet Vegetarian

-lormone levels following surgical and medical castration： defining optimal androgen suppression

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Asian Journal of Andrology 2018年第4期20卷 405-406页

作者： Michael T Schweizer Michael L Hancock Robert H Getzenberg evan Y Yu Division of Oncology Department of Medicine University of Washington Seattle WA 98116 USA Clinical Research Division Fred Hutchinson Cancer Research Center Seattle WA 98116 USA Veru Healthcare Miami FL 33137 USA

Dear Editor, In the 1940s, Charles Huggins discovered that surgical castration produced remarkable palliative benefits for men with advanced prostate cancer, an effect we now understand to be mediated through deprivi... 详细信息

关键词： FREE TESTOSTERONE DEPRIVATION THERAPY PROSTATE-CANCER ADRENAL-GLANDS MEN