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Portugal's first major forensic case and the genesis of forensic toxicology:10 years of research to reconstruct the event

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Forensic Sciences Research 2019年第1期4卷 69-81页

作者： ricardo Jorge Dinis-Oliveira Department of Sciences IINFACTS–Institute of Research and Advanced Training in Health Sciences and TechnologiesUniversity Institute of Health Sciences(IUCS)CESPUCRLGandraPortugal UCIBIO-REQUIMTE Laboratory of ToxicologyDepartment of Biological SciencesFaculty of PharmacyUniversity of PortoPortoPortugal Department of Public Health and Forensic Sciences and Medical EducationFaculty of MedicineUniversity of PortoPortoPortugal

The"Crime of Flores Street"is one of the most famous cases of poisoning to divide public opinion in Portugal in the late 19th century, and it also demonstrated the weaknesses of the Portuguese medicolegal system and attested to the importance of toxicological analysis. Vicente Urbino de Freitas was a prominent doctor, graduating from the Faculty of Medicine of the University of Coimbra in 1875. He later became Professor of Physiology at the Porto Medical-Surgical School and author of a number of books on leprosy. In 1877, he married Maria das Dores Basto Sampaio Freitas, and this was followed by the death of a number of her close relatives in suspicious circumstances, notably her brother José António Sampaio Junior and nephew Mário Guilherme Augusto de Sampaio. This review aims to retell the story of Portugal's first significant medicolegal case as well as the accompanying judicial drama that gave birth to Forensic Toxicology in Portugal and prompted the medicolegal organization that exists today. This research was carried out over a 10-year period and repre-sents undeniable historical value given the rarity of the facts compiled. At the heart of this forensic case was the use of toxicological analyses in court for which the Chemist Antònio Joaquim Ferreira da Silva played a key role. This toxicological report revealed high concen-trations of morphine, delphinine and narceine in viscera and in Mario's urine. The Mario's cause of death was attributed to poisoning by opium alkaloids. Despite the strong judicial evidence, doubts still remains as to whether Vicente Urbino de Freitas was a"monster"or a victim of circumstances and a hapless martyr.

关键词： Forensic sciences forensic toxicology Vicente Urbino de Freitas António Joaquim Ferreira da Silva Medical-Surgical School Mário Guilherme Augusto de Sampaio

Modeling considerations in seismic assessment of RC bridges using state-of-practice structural analysis software tools

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Frontiers of Structural and Civil Engineering 2018年第1期12卷 109-124页

作者： ricardo MONTEIRO Miguel ARAUJO Raimundo DELGADO Mario o MARQUES School of Advanced Studies IUSS Pavia Italy Department of Civil Engineering Faculty of Engineering University of Porto Portugal

The increasing awareness of the general society toward the seismic safety of structures has led to more restrictive performance requirements hence, many times, to the need of using new and more accurate methods of analysis of structures. Among these, nonlinear static procedures are becoming, evermore, the preferred choice of the majority of design codes, as an alternative to complete nonlinear time-history analysis for seismic design and assessment of structures. The many available software tools should therefore be evaluated and well understood, in order to be easily and soundly employed by the practitioners. The study presented herein intends to contribute to this need by providing further insight with respect to the use of commonly employed structural analysis software tools in nonlinear analysis of bridge structures. A comparison between different nonlinear modeling assumptions is presented, together with the comparison with real experimental results. Furthermore, alternative adaptive pushover procedures are proposed and applied to a case study bridge, based on a generic plastic hinge model. The adopted structural analysis program proved to be accurate, yielding reliable estimates, both in terms of local plastic hinge behavior and global structural behavior.

关键词： nonlinear analysis pushover RC bridges structural modelling software

Expansion Planning for Renewable Integration in Power System of Regions with Very High Solar Irradiation

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Journal of Modern Power Systems and Clean Energy 2021年第3期9卷 485-494页

作者： Musfer Alraddadi Antonio J.Conejo ricardo M.Lima the Department of Electrical and Computer Engineering The Ohio State UniversityColumbusOH 43210USA the Department of Integrated Systems Engineering and the Department of Electrical and Computer Engineering The Ohio State UniversityColumbusOH 43210USA King Abdullah University of Science and Technology Thuwal 23955-6900Kingdom of Saudi Arabia

In this paper,we address the long-term generation and transmission expansion planning for power systems of regions with very high solar *** target the power systems that currently rely mainly on thermal generators and that aim to adopt high shares of renewable *** propose a stochastic programming model with expansion alternatives including transmission lines,solar power plants(photovoltaic and concentrated solar),wind farms,energy storage,and flexible combined cycle gas *** model represents the longterm uncertainty to characterize the demand growth,and the short-term uncertainty to characterize daily solar,wind,and demand *** use the Saudi Arabian power system to illustrate the functioning of the proposed model for several cases with different renewable integration *** results show that a strong dependence on solar power for high shares of renewable sources requires high generation capacity and storage to meet the night demand.

关键词： Generation and transmission expansion planning uncertainty solar power wind power

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A Novel Iterative Velocity Control Algorithm and Its FPGA Implementation Based on Trigonometric Function

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Chinese Journal of Electronics 2019年第2期28卷 237-245页

作者： WEN Quangang LIANG Yanchun Adriano Tavares ricardo Teixeira WU Chunguo Key Laboratory of Symbol Computation and Knowledge Engineering of Ministry of Education College of Computer Science and Technology Jilin University Zhuhai Laboratory of Key Laboratory of Symbol Computation and Knowledge Engineering of Ministry of Education Zhuhai College of Jilin University Department of Industrial Electronics University of Minho Campus de Azurm

The servo motor’s flexible acceleration/deceleration(acc/dec) control is an emerging research topic in the automation field. A velocity control algorithm based on trigonometric function is proposed in this *** required parameters, it transforms trigonometric calculations into elementary mathematical operations and calculates the velocity controlling values iteratively, which could avoid trigonometric calculation and reduce the computation time. Experimental results show that the proposed algorithm is suitable for implementation on field programmable gate arrays and achieves a flexible controlling, enhancing both the equipment’s stability and reliability. It is promising to significantly improve the high-speed computerized numerical control equipment’s controlling accuracy, without a huge hardware resource consumption.

关键词： Acceleration Velocity control Algorithm design and analysis Field programmable gate arrays Servomotors

A simple and fast method to calculate the coil currents and the external poloidal flux and magnetic field for fixed boundary equilibria

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Plasma Science and Technology 2024年第11期26卷 65-70页

作者： ricardo FARENGO Pablo L GARCÍA-MARTÍNEZ Hugo E FERRARI Centro Atómico Bariloche Comisión Nacional de Energía AtómicaBariloche 8400Argentina Instituto Balseiro Universidad Nacional de CuyoBariloche 8400Argentina CONICET CCT-Patagonia Norte Bariloche 8400Argentina

A simple and fast method to calculate the coil currents and the external poloidal flux and magnetic field consistent with a given internal magnetohydrodynamic(MHD) equilibrium and coil geometry is presented. The constrained optimization technique employed allows to fix the exact position of the X-points. The external poloidal flux and field are calculated using Green's functions expressed in terms of elliptic integrals that are calculated using a fast and accurate *** calculation can be limited to the region between the plasma and the device wall. An example for a double null configuration is presented.

关键词： MHD equilibrium Green's functions tokamak

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An Explicit Formula for Two-Dimensional Singly-Periodic Regularized Stokeslets Flow Bounded by a Plane Wall

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Communications in Computational Physics 2018年第1期23卷 142-167页

作者： Forest O.Mannan ricardo Cortez Department of Mathematics Tulane UniversityNew OrleansLouisiana 70118-5665USA

We derive a closed form expression for the regularized Stokeslet in two space dimensions with periodic boundary conditions in the x-direction and a solid plane wall at y=*** accommodate the no-slip condition on the wall,a system of images for the regularized Stokeslets was *** periodicity is enforced by writing all elements of the image system in terms of a Green’s function whose periodic extension is *** the formulation is derived in the context of regularized Stokeslets,the expression for the traditional(singular)Stokeslet is easily found by taking the limit as the regularization parameter approaches *** new formulation is validated by comparing results of two test problems:the Taylor infinite waving sheet and the motion of a cylinder moving near a *** an example of an application,we use our formulation to compute the motion and flow generated by cilia using a model that does not prescribe the motion so that the beat period and synchronization of neighboring cilia are a result of the forces developed along the cilia.

关键词： Regularized Stokeslets singly-periodic flow method of images

Lagrangian Mesh Model with Regridding for Planar Poiseuille Flow

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Communications in Computational Physics 2017年第6期22卷 112-132页

作者： Jingxuan Zhuo ricardo Cortez Robert Dillon Department of Mathematics and Statistics Washington State UniversityUSA Department of Mathematics Tulane UniversityUSA

Many biological settings involve complex fluids that have non-Newtonian mechanical responses that arise from suspended *** contrast,Newtonian fluids are liquids or mixtures of a simple molecular structure that exhibit a linear relationship between the shear stress and the rate of *** modeling complex fluids,the extra stress from the non-Newtonian contribution must be included in the governing *** this study we compare Lagrangian mesh and Oldroyd-B formulations of fluidstructure interaction in an immersed boundary *** start-up phase of planar Poiseuille flow between two parallel plates is used as a test case for the fluid *** Newtonian and Oldroyd-B fluids there exist analytical solutions which are used in the comparison of simulation and theoretical *** Lagrangian mesh results are compared with Oldroyd-B using comparable parameters.A regridding algorithm is introduced for the Lagrangian mesh *** show that the Lagrangian mesh model simulations with regridding produce results in close agreement with the Oldfoyd-B model.

关键词： Lagrangian mesh model Oldroyd-B immersed boundary method viscoelastic fluid regridding methods

Effects of meal size and proximal-distal segmentation on gastric activity

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World Journal of Gastroenterology 2010年第46期16卷 5861-5868页

作者： Madileine F Américo Marjorie V Ietsugu Fernando G Romeiro Luciana A Corá ricardo B Oliveira José ricardo A Miranda Department of Physics and Biophysics IBBUNESP-Sao Paulo State University Institute of Biological Sciences and Health ICBSUFMT-University of Mato Grosso Department of Clinical Medicine FMBUNESP-Sao Paulo State University Department of Clinical Medicine FMRPUSP-University of So Paulo UNCISAL-Alagoas State University of Health Sciences

AIM:To evaluate the effects of meal size and three segmentations on intragastric distribution of the meal and gastric motility,by ***:Twelve healthy volunteers were randomly assessed,twice,by *** test meal consisted of 60 or 180 mL of yogurt labeled with 64 MBq 99m Tc-tin *** and posterior dynamic frames were simultaneously acquired for 18 min and all data were analyzed in *** proximal-distal segmentations using regions of interest were adopted for both ***:Intragastric distribution of the meal between the proximal and distal compartments was strongly influenced by the way in which the stomach was divided,showing greater proximal retention after the 180 *** important finding was that both dominant frequencies (1 and 3 cpm) were simultaneously recorded in the proximal and distal stomach;however,the power ratio of those dominant frequencies varied in agreement with the segmentation adopted and was independent of the meal ***:It was possible to simultaneously evaluate the static intragastric distribution and phasic contractility from the same recording using our scintigraphic approach.

关键词： Gastric motility Phasic contractions Proximal stomach Scintigraphy Meal size

Nutritional therapy for hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2021年第10期13卷 1440-1452页

作者： Astrid Ruiz-Margáin Berenice M Román-Calleja Paulina moreno-Guillén JoséA González-Regueiro DeyaniraKúsulas-Delint Alejandro Campos-Murguía Nayelli C Flores-García ricardo Ulises Macías-Rodríguez Liver Nutrition Clinic Department of GastroenterologyInstituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico City 14080Mexico Liver Fibrosis and Nutrition Lab MICTLÁN-Network(Mechanisms of Liver InjuryCell Death and Translational Nutrition in Liver Diseases-Research Network)Mexico City 14080Mexico Department of Gastroenterology Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico City 14080Mexico

Hepatocellular carcinoma(HCC)is the most frequent primary liver cancer and presents together with cirrhosis in most *** addition to commonly recognized risk factors for HCC development,such as hepatitis B virus/hepatitis C virus infection,age and alcohol/tobacco consumption,there are nutritional risk factors also related to HCC development including high intake of saturated fats derived from red meat,type of cooking(generation of heterocyclic amines)and contamination of foods with *** the contrary,protective nutritional factors include diets rich in fiber,fruits and vegetables,n-3 polyunsaturated fatty acids and *** the patient is being evaluated for staging and treatment of HCC,special attention should be paid to nutritional support,including proper nutritional assessment and therapy by a multidisciplinary *** must be considered that these patients usually develop HCC on top of long-lasting cirrhosis,and therefore they could present with severe *** complications should be properly addressed and considered for nutritional *** addition to traditional methods,functional testing,phase angle and computed tomography scan derived skeletal muscle index-L3 are among the most useful tools for nutritional *** therapy should be centered on providing enough energy and protein to manage the increased requirements of both cirrhosis and *** with branched-chain amino acids is also recommended as it improves response to treatment,nutritional status and survival,and finally physical exercise must be encouraged and adapted to individual needs.

关键词： Sarcopenia Liver Cancer Diet Branched-chain amino acids Nutrition