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全过程人民民主制度的逻辑结构、显著优势和健全路径

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马克思主义研究 2024年第3期 73-85,156页

作者：任鹏东北大学马克思主义学院辽宁沈阳110169

全过程人民民主制度是由根本制度、基本制度、重要制度、具体制度构成的制度体系,呈现出全面、广泛、有机衔接的结构关系,具有话语表征、实践形塑、价值规引等重要功能。从制度生成、制度体系、制度特性和制度效能等方面来看,全过程人... 详细信息

全过程人民民主制度是由根本制度、基本制度、重要制度、具体制度构成的制度体系,呈现出全面、广泛、有机衔接的结构关系,具有话语表征、实践形塑、价值规引等重要功能。从制度生成、制度体系、制度特性和制度效能等方面来看,全过程人民民主制度具有显著优势,破除了对西式民主制度优越论的迷思。新征程上,我们要坚定制度自信、推进制度健全,进一步提升全过程人民民主制度的适应性、增强全过程人民民主制度的可操作性、促进全过程人民民主制度的发展性,不断提高全过程人民民主制度化、规范化、程序化水平。

关键词：全过程人民民主制度中国共产党领导制度人民当家作主

宫腔镜下钬激光治疗子宫黏膜下肌瘤的效果及对性激素、性生活质量的影响

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解放军医药杂志 2021年第2期33卷 70-74页

作者：任秀朋崔微微定州市人民医院妇产科河北定州073000

目的探讨宫腔镜下钬激光治疗子宫黏膜下肌瘤的效果及对性激素、性生活质量的影响。方法选取我院妇科2018年1月—2019年5月收治的子宫黏膜下肌瘤88例,按照治疗方法的不同分为观察组51例和对照组37例,观察组给予宫腔镜下钬激光治疗,对照... 详细信息

目的探讨宫腔镜下钬激光治疗子宫黏膜下肌瘤的效果及对性激素、性生活质量的影响。方法选取我院妇科2018年1月—2019年5月收治的子宫黏膜下肌瘤88例,按照治疗方法的不同分为观察组51例和对照组37例,观察组给予宫腔镜下钬激光治疗,对照组给予宫腔镜电切术治疗。比较2组手术时间、术中出血量、术后疼痛程度、术后并发症及术后住院时间、月经恢复正常时间。比较2组术前、术后3个月血清促卵泡生长激素(FSH)、黄体生成素(LH)、雌二醇(E 2)水平,比较2组术前、术后6个月性生活质量评分。结果与对照组比较,观察组手术时间、术后住院时间及月经恢复正常时间显著缩短,术中出血量显著减少,术后视觉模拟疼痛评分显著降低(P0.05)。与术前比较,2组术后6个月各项性功能评分均显著升高,且观察组高于对照组(P<0.05,P<0.01)。结论宫腔镜下钬激光治疗子宫黏膜下肌瘤除具有手术时间短、术中出血量少、疼痛轻、术后恢复快、安全性高的优势外,对患者性激素水平及性生活质量的影响较小。

关键词：肌瘤,子宫钬激光手术宫腔镜电切术手术后并发症卵泡刺激素促黄体激素雌二醇

Anisotropy measurements and characterization of the Qingshankou shale

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Applied Geophysics 2024年第3期21卷 468-478,617页

作者： Li Qing-feng Yan Xue-hong Yan Wei-lin ren Li Wang peng Han Jian-qiang Xia Xue Chen Hao Daqing Oilfield Exploration Division Daqing163000HeilongjiangChina Daqing Branch Company of CNPC Logging Daqing163000HeilongjiangChina Exploration and Development Research Institute of Daqing Oilfield Co. Ltd.Daqing163712China State Key Laboratory of Acoustics Institute of AcousticsChinese Academy of SciencesBeijing100190China

Qingshankou shale(Gulong area,China)exhibits strong acoustic anisotropy characteristics,posing significant challenges to its exploration and *** this study,the five full elastic constants and multipole response law of the Qingshankou shale were studied using experimental *** show that the anisotropy parametersϵandγin the study region are greater than 0.4,whereas the anisotropy parameterδis smaller,generally *** simulations show that the longitudinal and transverse wave velocities of these strong anisotropic rocks vary significantly with inclination angle,and significant differences in group velocity and phase velocity are also *** logging measures the group velocity in dipped boreholes;this differs from the phase velocity to some *** the dip angle increases,the longitudinal and SH wave velocities increase accordingly,while the qSV-wave velocity initially increases and then decreases,reaching its maximum value at a dip of approximately 40°.These results provide an effective guide for the correction and modeling of acoustic logging time differences in the region.

关键词： Transverse isotropy anisotropy parameter sonic logging group velocity phase velocity

Tuberous sclerosis complex combined with primary lymphedema:A case report

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World Journal of Clinical Cases 2024年第15期12卷 2642-2648页

作者： Xing-peng Li Xiao-Li Sun Xin Liu Zhe Wen Li-Hua Jiang Yan Fu Yun-Long Yue ren-Gui Wang Department of Radiology Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijing 100038China Department of Lymph Surgery Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijing 100038China Department of Nuclear Medicine Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijing 100038China Department of MRI Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijing 100038China

BACKGROUND Tuberous sclerosis complex(TSC)and primary lymphedema(PLE)are both rare diseases,and it is even rarer for both to occur in the same *** this work,we have provided a detailed description of a patient's clinical presentation,imaging findings,and *** a retrospective analysis was conducted on 14 published relevant case *** SUMMARY A 16-year-old male came to our hospital for treatment due to right lower limb *** swelling is already present from *** patient’s memory had been progressively *** had occurred 1 year prior at an unknown *** patient was diagnosed with TSC combined with PLE through multimodal imaging examination:Computed tomography,magnetic resonance imaging,and *** patient underwent *** swelling of the patient's right lower limb significantly improved after *** did not *** taking antiepileptic drugs and *** TSC with PLE is a rare and systemic *** can detect lesions of this disease,which are important for diagnosis and treatment.

关键词： Tuberous sclerosis complex Lymphedema Sirolimus Multimodal imaging examination Case report

Identification of novel mammalian viruses in tree shrews(Tupaia belangeri chinensis)

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Zoological Research 2024年第2期45卷 429-438页

作者： Hong Zhou ren-Rong Tian xiu-Rong Wang Jin-Xuan Yang Yun-Xiao Wang Ming-Liang Zhao Xu-Dong Zhang Yu-Hua Ma Long-Bao Lv Edward CHolmes Yong-Tang Zheng Wei-Feng Shi School of Clinical and Basic Medical Sciences Shandong First Medical University&Shandong Academy of Medical SciencesJi’nanShandong 250117China Key Laboratory of Emerging Infectious Diseases in Universities of Shandong Shandong First Medical University and Shandong Academy of Medical SciencesTaianShandong 271000China Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesCenter for Biosafety Mega-ScienceKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China School of Public Health Shandong First Medical University&Shandong Academy of Medical SciencesJi’nanShandong 250117China National Resource Center for Non-Human Primates Kunming Primate Research CenterKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650107China Sydney Institute for Infectious Diseases School of Medical SciencesThe University of SydneySydneyNew South Wales 2006Australia Department of Infectious Diseases Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Shanghai Institute of Virology Shanghai Jiao Tong University School of MedicineShanghai 200025China

The Chinese tree shrew(Tupaia belangeri chinensis),a member of the mammalian order Scandentia,exhibits considerable similarities with primates,including humans,in aspects of its nervous,immune,and metabolic *** similarities have established the tree shrew as a promising experimental model for biomedical research on cancer,infectious diseases,metabolic disorders,and mental health ***,we used metatranscriptomic sequencing to analyze plasma,as well as oral and anal swab samples,from 105 healthy asymptomatic tree shrews to identify the presence of potential zoonotic *** total,eight mammalian viruses with complete genomes were identified,belonging to six viral families,including Flaviviridae,Hepeviridae,Parvovirinae,Picornaviridae,Sedoreoviridae,and ***,the presence of rotavirus was recorded in tree shrews for the first *** viruses-hepacivirus 1,parvovirus,and picornavirus-exhibited low genetic similarity(94%)to known viral *** analyses also revealed that the rotavirus and mammalian orthoreovirus identified in this study may be novel *** findings provide insights into the diverse viral spectrum present in captive Chinese tree shrews,highlighting the necessity for further research into their potential for crossspecies transmission.

关键词： Tree shrew(Tupaia belangeri chinensis) Meta-transcriptomic sequencing Mammalian viruses Genomic analysis

Intranasal boosting with RBD-HR protein vaccine elicits robust mucosal and systemic immune responses

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Genes & Diseases 2024年第4期11卷 327-339页

作者： Li Chen Wenyan ren Hong Lei Jiayu Wang Haiying Que Dandan Wan Aqu Alu Dandan peng Minyang Fu Weiqi Hong Yuhe Huang Xiangrong Song Guangwen Lu Xiawei Wei Laboratory of Aging Research and Cancer Drug Target State Key Laboratory of Biotherapy and Cancer CenterNational Clinical Research Center for GeriatricsWest China HospitalSichuan UniversityChengduSichuan 610041China

The emergence of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)variants has decreased the efficacy of SARs-CoV-2 vaccines in containing coronavirus disease 2019(CoVID-19)over time,and booster vaccination strategies are urgently necessitated to achieve sufficient *** immunization can improvemucosal immunity,offer-ing protection against the infection and sustaining the spread of *** this study,an intranasal booster of the RBD-HR vaccine after two doses of the mRNA vaccine significantly increased the levels of specific binding antibodies in serum,nasal lavage fluid,and bronchoal-veolar lavage fluid compared with only two doses of mRNA *** intranasal boosting with the RBD-HR vaccine,the levels of serum neutralizing antibodies against prototype and variant strains of SARS-Cov-2 pseudoviruses weremarkedly higher than those in mice receiving mRNA vaccine alone,and intranasal boosting with the RBD-HR vaccine also inhibited the bind-ing of RBD to hACE2 ***,the heterologous intranasal immunization regimen promoted extensive memory T cell responses and activated CD103+dendritic cells in the respiratory mucosa,and potently enhanced the formation of T follicular helper cells and germinal center B cells in vital immune organs,including mediastinal lymph nodes,inguinal lymph nodes,and ***,these data infer that heterologous intranasal boosting with the RBD-HR vaccine elicited broad protective immunity against SARS-CoV-2 both locallyandsystemically.

关键词： Heterologous immunization Intranasal immunization mRNA vaccine SARS-CoV-2 Subunitprotein vaccine

Flavonoids from mulberry leaves inhibit fat production and improve fatty acid distribution in adipose tissue in finishing pigs

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Animal Nutrition 2024年第1期16卷 147-157页

作者： Yingying Liu Yinglin peng Chen Chen Huibo ren Ji Zhu Yuan Deng Qingming Cui Xionggui Hu Jianhua He Huali Li Xinghui Zhu Yulong Yin Jun He Yi Xiao College of Animal Science and Technology Hunan Agricultural UniversityChangsha410128China Hunan Institute of Animal and Veterinary Science Changsha410131China Key Laboratory of Conservation and Genetic Analysis of Local Pig Breed Germplasm Resources Changsha410131China College of Information and Intelligence Hunan Agricultural UniversityChangsha410128China Institute of Subtropical Agriculture Chinese Academy of SciencesChangsha410125China

This study evaluated the effects of flavonoids from mulberry leaves(FML)on plasma biochemical indices,serum activities of lipid metabolism-related enzymes,fat morphology,fatty acid composition,and lipid metabolism in different adipose tissues of finishing *** used 120 Chinese hybrid barrows of Berkshire and Bama mini-pigs with an average initial body weight of 45.11±4.23 *** pigs were randomly assigned to five treatment groups and fed a control diet based on corn,soybean meal,and wheat bran or a control diet supplemented with 0.02%,0.04%,0.08%,or 0.16%*** experimental group had six replicates(pens),with four pigs per *** a 7-d adaptation period,the feeding trial was conducted for 58 *** and adipose tissue samples were collected from 30 pigs(one pig per pen)at the end of the *** results showed that FML supplementation significantly decreased the feed intake to body gain ratio,the plasma concentrations of total cholesterol and free fatty acids,and the serum activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase(linear or quadratic effects,Prent adipose *** findings suggest that FML improved growth performance,regulated lipid met

关键词： Finishing pig Mulberry leaf Flavonoid Lipid metabolism Fatty acid Lard

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Dipeptidyl peptidase-4 inhibitors and the risk of infection: A systematic review and meta-analysis of cardiovascular outcome trials

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World Journal of Diabetes 2024年第5期15卷 1011-1020页

作者： Na Yang Li-Yun He peng Liu Zi-Yi Li Yu-Cheng Yang Fan Ping Ling-Ling Xu Wei Li Hua-Bing Zhang Yu-xiu Li Department of Endocrinology Key Laboratory of Endocrinology of National Health CommissionPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Endocrinology The First Affiliated Hospitaland College of Clinical Medicine of Henan University of Science and TechnologyLuoyang 471000Henan ProvinceChina

BACKGROUND Since adverse events during treatment affect adherence and subsequent glycemic control,understanding the safety profile of oral anti-diabetic drugs is imperative for type 2 diabetes mellitus(T2DM)*** To evaluate the risk of infection in patients with T2DM treated with dipeptidyl-peptidase 4(DPP-4)*** Electronic databases were *** selection criteria included randomized controlled trials focused on cardiovascular *** these studies,the effects of DPP-4 inhibitors were directly compared to those of either other active anti-diabetic treatments or *** trials involving 53616 patients were deemed *** calculated aggregate relative risks employing both random-effects and fixed-effects approaches,contingent upon the *** The application of DPP-4 inhibitors showed no significant link to the overall infection risk[0.98(0.95,1.02)]or the risk of serious infections[0.96(0.85,1.08)],additionally,no significant associations were found with opportunistic infections[0.69(0.46,1.04)],site-specific infections[respiratory infection 0.99(0.96,1.03),urinary tract infections 1.02(0.95,1.10),abdominal and gastrointestinal infections 1.02(0.83,1.25),skin structure and soft tissue infections 0.81(0.60,1.09),bone infections 0.96(0.68,1.36),and bloodstream infections 0.97(0.80,1.18)].CONCLUSION This meta-analysis of data from cardiovascular outcome trials revealed no heightened infection risk in patients undergoing DPP-4 inhibitor therapy compared to control cohorts.

关键词： T2DM drugs treatment

In-situ physical/chemical cross-linked hydrogel electrolyte achieving ultra-stable zinc anode-electrolyte interface towards dendrite-free zinc ion battery

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Journal of Energy Chemistry 2024年第10期97卷 342-351页

作者： Chen-Yang Li Jiang-Lin Wang Dong-Ting Zhang Min-peng Li Hao Chen Wei-Hai Yi Xin-Ying ren Bao Liu Xue-Feng Lu Mao-Cheng Liu State Key Laboratory of Advanced Processing and Recycling of Non-ferrous Metals Lanzhou University of Technology School of Materials Science and Engineering Lanzhou University of Technology Chaowei Power Group Co. LTD School of Vehicle Engineering Jiangsu University

Hydrogen evolution reaction（HER）,zinc corrosion,and dendrites growth on zinc metal anode are the major issues limiting the practical applications of zinc-ion ***,an in-situ physical/chemical cross-linked hydrogel electrolyte（carrageenan/polyacrylamide/ZnSO4,denoted as CPZ） has been developed to stabilize the zinc anode-electrolyte interface,which can eliminate side reactions and prevent dendrites *** in-situ CPZ hydrogel electrolyte improves the reversibility of zinc anode due to eliminating side reactions caused by active water ***,the electrostatic interaction between the SO4-groups in CPZ and Zn2+can encourage the preferential deposition of zinc atoms on（002） crystal plane,which achieve dendrite-free and homogeneous zinc *** in-situ hydrogel electrolyte offers a streamlined approach to battery manufacturing by allowing for direct integration into the ***,the Zn//Zn half battery with CPZ hydrogel electrolyte can enable an ultra-long cycle over 5500 h at a current density of 0.5 mA cm-2,and the Zn//Cu half battery reach an average coulombic efficiency of 99.37%.The Zn//V2O5-GO full battery with CPZ hydrogel electrolyte demonstrates94.5% of capacity retention after 2100 *** study is expected to open new thought for the development of commercial hydrogel electrolytes for low-cost and long-life zinc-ion batteries.

关键词： Dendrites growth Hydrogen evolution reaction and zinc corrosion In-suit CPZ hydrogel electrolyte Zinc anode-electrolyte interface Zn ion batteries