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Hybrid 2D–3D optical devices for integrated optics by direct laser writing

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Light(Science & Applications) 2014年第1期3卷 173-181页

作者： Martin Schumann Tiemo Buckmann Nico Gruhler Martin wegener Wolfram Pernice Institute of Applied Physics and DFG-Center for Functional Nanostructures(CFN) Karlsruhe Institute of Technology(KIT)76131 KarlsruheGermany Institute of Nanotechnology(INT) 76344 Eggenstein-LeopoldshafenGermany

Integrated optical chips have already been established for application in optical *** also offer interesting future perspectives for integrated quantum optics on a *** present,however,they are mostly fabricated using essentially planar fabrication approaches like electron-beam lithography or UV optical *** further design options would arise if one had complete fabrication freedom in regard to the third dimension normal to the chip without having to give up the virtues and the know-how of existing planar fabrication *** a step in this direction,we here use three-dimensional dip-in direct-laser-writing optical lithography to fabricate three-dimensional polymeric functional devices on pre-fabricated planar optical chips containing Si3N4 waveguides as well as grating couplers made by standard electron-beam *** first example is a polymeric dielectric rectangular-shaped waveguide which is connected to Si3N4 waveguides and that is adiabatically twisted along its axis to achieve geometrical rotation of linear polarization on the *** rotator’s broadband performance at around 1550 nm wavelength is verified by polarization-dependent grating *** polarization rotation on the optical chip cannot easily be achieved by other *** second example is a whispering-gallery-mode optical resonator connected to Si_(3)N_(4) waveguides on the chip via polymeric *** mechanically connecting the latter to the disk,we can control the coupling to the resonator and,at the same time,guarantee mechanical stability of the three-dimensional architecture on the chip.

关键词： direct laser writing integrated optics nanophotonic circuits polarization conversion

Monitoring of central corneal thickness after phacoemulsification—comparison of statical and rotating Scheimpflug pachymetry,and spectral-domain OCT

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International Journal of Ophthalmology(English edition) 2022年第8期15卷 1266-1272页

作者： Daniel M.Handzel Carsten H.Meyer Alfred wegener Augenaerzte im Altstadt-Carree Fulda 36037Germany University Eye Hospital Philipps-UniversitätMarburg 35032Germany University Eye Hospital Rheinische Friedrich-WilhelmsUniveritätBonn 53124Germany

AIM:To explore the possibility of deploying three contactless devices(static and rotating Scheimpflug technology,spectral domain optical coherence tomography)for measuring central corneal thickness(CCT)in preoperative and postoperative examinations of cataract ***:Totally 72 patients who had undergone surgery without complications were *** CCT was measured prior to the operation,as well as on the first,5th-7th and 28th day following the operation using the Nidek NT 530-P,Sirius?,and Topcon OCT-2000 ***:A significant postoperative increase and subsequent decrease in CCT was identified with all three *** correlations were highly significant and thus reflect a very good degree of comparability at all times with the exception of the rotating Scheimpflug *** postoperative results from the latter differed significantly from the other *** correlations were Sirius/Topcon(P=0.010)and Sirius/Nidek(Prence could be identified in the comparison between Topcon and Nidek(P=0.056).CONCLUSION:All three devices are suitable for postoperative monitoring of *** measurement results are only comparable to a limited extent and not interchangeable in the course of treating a single *** is due to the different imaging technology used in the devices and the resulting modalities for conducting the measurements.

关键词： cataract surgery pachymetry corneal thickness Scheimpflug imaging optical coherence tomography

The Psb32 Protein Aids in repairing Photodamaged Photosystem II in the Cyanobacterium Synechocystis 6803

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Molecular Plant 2011年第6期4卷 1052-1061页

作者： Kimberly M. wegener Stefan Bennewitz ralf Oelmuller Himadri B. Pakrasi Department of Biology Washington University St Louis MO 63130 USA Present address： Division of Biological Sciences University of Missouri Columbia MO 65211 USA Institute of Plant Physiology Friedrich-Schiller-University Jena Dornburger Str. 159 D-07743 Jena Germany

Photosystem II （PSII）, a membrane protein complex, catalyzes the photochemical oxidation of water to molecular oxygen. This enzyme complex consists of approximately 20 stoichiometric protein components. However, due to the highly energetic reactions it catalyzes as part of its normal activity, PSII is continuously damaged and repaired. With advances in protein detection technologies, an increasing number of sub-stoichiometric PSII proteins have been identified, many of which aid in the biogenesis and assembly of this protein complex. Psb32 （SII1390） has previously been identified as a protein associated with highly active purified PSII preparations from the cyanobacterium Synechocystis sp. PCC 6803. To investigate its function, the subcellular localization of Psb32 and the impact of deletion of the psb32 gene on PSII were analyzed. Here, we show that Psb32 is an integral membrane protein, primarily located in the thylakoid membranes. Al- though not required for cell viability, Psb32 protects cells from oxidative stress and additionally confers a selective fitness advantage in mixed culture experiments. Specifically, Psb32 protects PSII from photodamage and accelerates its repair. Thus, the data suggest that Psb32 plays an important role in minimizing the effect of photoinhibition on PSII.

关键词： Photosynthesis reactive oxygen species photoinhibition photodamage.

Differential treatment and early outcome in the interventional endoscopic management of pancreatic pseudocysts in 27 patients

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World Journal of Gastroenterology 2006年第26期12卷 4175-4178页

作者： Uwe Will Conrad wegener Kai-Ivo Graf Igor Wanzar Thomas Manger Frank Meyer Department of Gastroenterology Municipal Hospital D-07548 GeraGermany Department of Surgery Municipal Hospital D-07548 GeraGermany Department of Surgery University Hospital D-39120 MagdeburgGermany

AIM： Pancreatic pseudocysts （PPC） as a complication of pancreatitis are approached only in the case of abdominal pain, infection, bleeding, and compression onto the gastrointestinal tract or biliary tree. METHODS： From 02/01/2002 to 05/31/2004, all con- secutive patients with symptomatic PPC who underwent an interventional endoscopic approach were evaluated in this pilot case-series study： Group （Gr.） Ⅰ-Primary percutaneous （external）, ultrasound-guided drainage. Gr. Ⅱ- Primary EUS-guided cystogastrostomy. Gr. Ⅲ-EUS-guided cystogastrostomy including intracystic necrosectomy. rESULTS：（=＂follow up＂： n = 27）： Gr. Ⅰ （n = 9; 33.3%）： No complaints （n = 3）; change of an external into an internal drainage （n = 4）; complications：（a） bleeding （n = 1） followed by 3 d at ICU, discharge after 40 d; （b） septic shock （n = 1） followed by ICU and several laparotomies for programmed lavage and necrosectomy, death after 74 d. Gr. Ⅱ （n = 13; 48.1%）： No complaints （n = 11）; external drainage （n = 2）; complications/problems out of the 13 cases： 2nd separate pseudocyst （n = 1） with external drainage （since no communication with primary internal drainage）; infection of the residual cyst （n = 1）＋ following external drainage; spontaneous PPC perforation （n = 1）＋ following closure of the opening of the cystogastrostomy using clips and subsequently ICU for 2 d. Gr. Ⅲ （n = 5; 18.5%）： No complaints in all patients, in average two endoscopic procedures required （range, 2-6）. CONCLUSION： Interventional endoscopic management of pancreatic pseudocysts is a reasonable alternative treatment option with low invasiveness compared to surgery and an acceptable outcome with regard to the complication rate （11.1%） and mortality （3.7%）, as shown by these initial study results.

关键词： Pancreatic pseudocyst Pancreatitis Interventional endoscopic approach

Mechanization technology:The key to sugarcane production in China

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International Journal of Agricultural and Biological Engineering 2013年第1期6卷 1-27页

作者： Ou Yinggang Malcolm wegener Yang Dantong Liu Qingting Zheng Dingke Wang Meimei Liu Haochun College of Engineering South China Agricultural UniversityGuangzhou 510642China School of Agriculture and Food Sciences The University of QueenslandBrisbaneQLD4072Australia

Sugarcane is an important cash crop in southern China now planted on about 1.5 million ha in the main production areas in Guangxi,Zhuang Autonomous region and Yunnan,Guangdong,and Hainan *** the cost of labor in China is increasing rapidly and the price of local sugar is uncompetitive with the product from mechanized international producers,China needs to change its sugarcane production methods from manual work to mechanization in order to catch up with international trends in this global *** a lot of effort in China have gone into sugarcane mechanization since the 1960s,the overall level of mechanization in sugarcane production is still only approximately 30%,which is about 20%lower than that achieved in the other main field *** all of the sugarcane grown in China is still harvested by *** order to summarize past experience and promote the mechanization of sugarcane production in China,this paper reviews the whole process of developing mechanization since 1960s and describes the current state of sugarcane mechanization in *** research currently being undertaken and the main obstacles to be overcome in developing a mechanized sugarcane production system,are *** design and testing of sugarcane harvesting machinery and its key components has been a significant research area by some Chinese universities,research institutes,and manufacturing companies in these past *** paper reviews that research and outlines the main achievements which have been made in this *** harvesting systems for sugarcane,and the appropriate harvesting patterns suitable for different growing conditions applying in China,have also been *** paper concludes with some comments on the future directions for progress in China’s mechanization of sugarcane production and some policy suggestions to facilitate the industry's transition.

关键词： mechanization technology sugarcane production sugarcane harvester sugarcane machinery development pattern

A shoe-box-sized 3D laser nanoprinter based on two-step absorption

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Light(Advanced Manufacturing) 2024年第2期5卷 115-122页

作者： Tobias Messer Michael Hippe Jingya(Lilyn)Gao Martin wegener Institute of Applied Physics(APH) Karlsruhe Institute of Technology(KIT)76128 KarlsruheGermany Institute of Nanotechnology(INT) Karlsruhe Institute of Technology(KIT)76128 KarlsruheGermany

State-of-the-art commercially available 3D laser micro-and nanoprinters using polymeric photoresists based on two-or multi-photon absorption rely on high-power pico-or femtosecond lasers,leading to fairly large and expensive ***,we have introduced photoresists based on two-step absorption instead of two-photon absorption,allowing for the use of small and inexpensive continuous-wave 405 nm wavelength GaN semiconductor laser diodes with light-output powers below 1 ***,using the identical photoresist system and similar laser diodes,we report on the design,construction,and characterization of a 3D laser nanoprinter that fits into a shoe *** shoe box contains all optical components,namely the mounted laser,the collimation-and beam-shaping optics,a miniature MEMS xy-scanner,a tube lens,the focusing microscope objective lens(NA=1.4,100×magnification),a piezo slip-stick z-stage,the sample holder,a camera monitoring system,LED sample illumination,as well as the miniaturized control electronics employing a *** present a gallery of example 3D structures printed with this *** achieve about 100 nm lateral spatial resolution and focus scan speeds of about 1 mm/***,our shoe-box-sized system can be made orders of magnitude less expensive than today’s commercial systems.

关键词： Two-step absorption Direct laser writing 3D laser nanoprinters Micro-electro-mechanical-systems scanner 3D nanostructures

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数据挖掘推动客户数据驱动车辆的开发进程

同济大学学报（自然科学版） 2021年第S1期49卷 1-10页

作者： wegener Jan VAN PUTTEN Sebastiaan NEUBECK Jens WAGNEr Andreas 斯图加特大学汽车工程学院德国斯图加特70049 奥迪股份公司德国英戈尔施塔特85049 斯图加特汽车工程与车辆发动机研究所德国斯图加特70049

对于汽车等面向消费者的行业,数据驱动的产品开发是一项关键的系统工程。数据驱动方法的前提是数据本身,由于现代车辆的联网能力不断提高,使得汽车制造商能够以内部总线信号的形式记录并储存客户数据。由于这些数据并不用于外部,只用于... 详细信息

对于汽车等面向消费者的行业,数据驱动的产品开发是一项关键的系统工程。数据驱动方法的前提是数据本身,由于现代车辆的联网能力不断提高,使得汽车制造商能够以内部总线信号的形式记录并储存客户数据。由于这些数据并不用于外部,只用于内部通信以保证车辆的安全性和功能性,这给这些数据的应用带来了一定的困难,因此汽车行业的主要问题在于如何利用数据挖掘技术从这些数据中提取客户需求及相关信息。为此,对上述数据应用问题进行了文献调研,并在此基础上开展数据挖掘的模拟研究,以确定现有数据挖掘过程在需求获取领域的适用性;进而提出一种扩展程序,使得数据挖掘技术能够应用于相关客户数据之中,从而加快车辆开发的进程。

关键词：车辆开发数据驱动数据挖掘跨行业数据挖掘标准流程数据驱动需求获取