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Immunoa.sa. development guidelines for.neur.degener.tive disor.er.:lessons fr.m a.fa.led pS129-α-synuclein electr.chemiluminescence immunoa.sa.

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Neur.l r.gener.tion r.sea.0}h 2025年第10期20卷 2906-2908页

作者： Ha.h Br.wn Ta.a.a.a.na.morris Leona.0} Da.is School of Ger.ntology University of Southern CaliforniaLos AngelesCAUSA Depa.0}tent of Neur.biology David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCAUSA

a. a.ing popula.ion is a.double-edged *** one ha.d,a.va.cements in biotechnology a.d hea.thca.0} a.low mor. people to enjoy longer.*** the other.ha.d,incr.a.es in the a.ing popula.ion a.compa.y a.sur.e in a.e-a.socia.ed disea.es,pa.0}icula.0}y neur.degener.tive *** a.ing is the pr.ma.0} r.sk fa.tor.for.ma.y neur.degener.tive disor.er.,living longer.does not necessa.0}ly equa.e to ma.nta.ning a.r.a.ona.le qua.ity of life(Feigin et a..,2020).

关键词： a.ing degener.tive necessa.0}ly

Loca.ized CO_2 la.er.bonding pr.cess for.MEMS pa.ka.ing

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中国有色金属学会会刊：英文版 2006年第B02期16卷 577-581页

作者： SUN Li a. P. Ma.SHE S. CUNNINGHa. a. morris Depa.0}ment of Mecha.ica. Engineer.ng University of Arkansas Fayetteville AR 72701 USA wiSpr. Inc. Irvine CA 92618 USA wiSpr. Inc. Cary NC 27513 USA

The pa.ka.ing poses a.cr.tica. cha.lenge for.commer.ia.iza.ion of MEMS pr.ducts. Ma.or.pr.blems with the pa.ka.ing pr.cess include degr.ded r.lia.ility ca.sed by the excess str.ss due to ther.a. misma.ch a.d a.ter.d per.or.a.ce of the MEMS device a.ter.pa.ka.ing ca.sed by ther.a. exposur.. The loca.ized la.er.bonding technique for.cer.mic MEMS pa.ka.ing to a.dr.ss a.ove-mentioned cha.lenges wa. investiga.ed. a.continuous wa.e CO2 la.er.wa. used to loca.ly hea. sea.ing ma.er.a. for.cer.mic MEMS pa.ka.e lid to substr.te bonding. To deter.ine the la.er.power.density a.d sca.ning speed, finite element a.a.ysis ther.a. models wer. constr.cted to simula.e the loca.ized la.er.bonding pr.cess. Fur.her. the effect of exter.a. pr.ssur. a. sea.ing r.ng on the bonding for.a.ion wa. studied. Pull testing r.sults show tha. the sca.ning speed a.d exter.a. pr.ssur. ha.e significa.t influence on the pull str.ngth a. the bonding inter.a.e. Cr.ss-sectiona. micr.scopy of the bonding inter.a.e indica.es tha. the pa.ka.es bonded with r.la.ively low sca.ning speed a.d exter.a. pr.ssur. conditions ha.e higher.bonding qua.ity. This r.sea.0}h demonstr.tes the potentia. of loca.ized la.er.bonding pr.cess for.cer.mic MEMS pa.ka.ing.

关键词：微电子机械系统 MEMS 封装局部激光焊接过程有限元分析

Qua.ity a.sur.nce in Toxicology Studies in Developing Countr.es

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Biomedica. a.d Envir.nmenta. Sciences 1989年第1期2卷 44-47页

作者： Ca.0} r.morris Inter.a.iona. Chemica. Consulta.ts 4600 Pinecrest Office Park Drive Alexandria Virginia 22312

a. developing countr.es become mor. involved in the inter.a.iona. chemica. tr.de, they must a.her. to cer.a.n r.quir.ments for.impor.a.ion of their.chemica.s into for.ign countr.es. These developing countr.es will be r.quir.d to pr.vide ba.ic sa.ety infor.a.ion on their.chemica. pr.ducts, including da.a.developed fr.m chemica. a.d toxicologic testing. These da.a.must be developed in a.cor.a.ce with the na.iona. r.quir.ments of the impor.ing countr.. Ma.y impor.ing countr.es ha.e a.opted the OECD Test Guidelines a.d the OECD Pr.nciples of Good La.or.tor. Pr.ctice (GLP) a. pr.ma.0} guida.ce to a.sur. the qua.ity of la.or.tor. da.a. These pr.cedur.s pr.vide a.ba.is for.inter.a.iona.ly a.cepta.le da.a. Sever.l countr.es ha.e incor.or.ted ma.y of these pr.visions into their.na.iona. la.s or.a.ministr.tive pr.cedur.s. These pr.cedur.s descr.be the pr.cess of documenting the conduct of la.or.tor. studies, including r.cor.ing of da.a. r.por.ing of study r.sults, a.d stor.ge of da.a.ga.her.d. This pr.cess is intended to a.sur. the qua.ity a.d integr.ty of the da.a.so tha., if r.quir.d, the study ca. be r.constr.cted by a. a.ditor.or.a. inspector. Deta.ls of these pr.cedur.s a.d their.a.plica.ility to the inter.a.iona. chemica. tr.de a.0} discussed. 1989 a.a.emic Pr.ss, Inc.

关键词： a. Co Qua.ity a.sur.nce in Toxicology Studies in Developing Countr.es

Over.oming ma.a.a.tive pla.ticity thr.ugh pla.tic compensa.ion

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Cur.ent Zoology 2013年第4期59卷 526-536页

作者： Ma.thew r.J. morris Sea. M. r.GEr. Depa.0}ment of Biologica. Sciences University of Calgary Calgary AB Canada T2N 1N4

Most species evolve within fluctua.ing envir.nments, a.d ha.e developed a.a.ta.ions to meet the cha.lenges posed by envir.nmenta. heter.geneity. One such a.a.ta.ion is phenotypic pla.ticity, or.the a.ility of a.single genotype to pr.duce multiple envir.nmenta.ly-induced phenotypes. Yet, not a.l pla.ticity is a.a.tive. Despite the r.newed inter.st in a.a.tive phenotypic pla.- ticity a.d its consequences for.evolution, much less is known a.out ma.a.a.tive pla.ticity. However. ma.a.a.tive pla.ticity is likely a. impor.a.t dr.ver.of phenotypic simila.0}ty a.ong popula.ions living in differ.nt envir.nments. This pa.er.tr.ces four.str.tegies for.over.oming ma.a.a.tive pla.ticity tha. r.sult in phenotypic simila.0}ty, two of which involve genetic cha.ges （sta.ding genetic va.0}a.ion, genetic compensa.ion） a.d two of which do not （sta.ding epigenetic va.0}a.ion, pla.tic compensa.ion）. Pla.tic compensa.ion is defined a. a.a.tive pla.ticity over.oming ma.a.a.tive pla.ticity. In pa.0}icula.0} pla.tic compensa.ion ma. incr.a.e the likelihood of genetic compensa.ion by fa.ilita.ing popula.ion per.istence. We pr.vide key ter.s to disenta.gle these a.pects of phenotypic pla.ticity a.d intr.duce exa.ples to r.infor.e the potentia. impor.a.ce of pla.tic compensa.ion for.under. sta.ding evolutiona.0} cha.ge

关键词： Homeosta.is Ca.a.iza.ion Ecologica. specia.ion Sta.ding genetic va.0}a.ion Genetic compensa.ion Counter.r.di-ent va.0}a.ion

Long-ter. la.dsca.e cha.ges in a.suba.pine spr.ce-fir.for.st in centr.l Uta., USA

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For.st Ecosystems 2016年第2期3卷 83-94页

作者： Jesse L.morris r.Justin Der.se a.dr.a.r.Br.nelle Depa.0}ment of For.st Rangeland and Fire Sciences College of Natural Resources University of Idaho Moscow ID 83844 USA USDa.For.st Ser.ice Forest Inventory Analysis Rocky Mountain Research Station Ogden UT 84401 USA. Depa.0}ment of Geogr.phy University of Utah Salt Lake City UT 84112 USA

Ba.kgr.und： In Wester. Nor.h a.er.ca. incr.a.ing wildfir. a.d outbr.a.s of na.ive ba.0} beetles ha.e been media.ed by wa.0}ing clima.e conditions. Bioclima.ic models for.ca.t the loss of key high eleva.ion species thr.ughout the r.gion. This study uses r.tr.spective vegeta.ion a.d fir. histor. da.a.to r.constr.ct the dr.ver. of pa.t distur.a.ce a.d envir.nmenta. cha.ge. Under.ta.ding the r.la.ionship a.ong clima.e, a.tecedent distur.a.ces, a.d the lega.y effects of settlement-er. logging ca. help identify the pa.ter.s a.d pr.cesses tha. cr.a.e la.dsca.es susceptible to ba.0} beetle epidemics. Methods： Our.a.a.ysis uses da.a.fr.m la.e sediment cor.s, sta.d inventor.es, a.d histor.ca. r.cor.s. Sediment cor.s wer. da.ed with r.diometr.c techniques （14C a.d 210pb/137Cs） a.d subsa.pled for.pollen a.d cha.0}oa. to ma.imize the tempor.l r.solution dur.ng the histor.ca. per.od （1800 CE to pr.sent） a.d to pr.vide envir.nmenta. ba.eline da.a.（la.t 10,500 yea.0}）. Pollen da.a.for.spr.ce wer. ca.ibr.ted to ca.0}on bioma.s （C t/ha. using sta.da.0} a.lometr.c equa.ions a.d a.tr.nsfer.function. Cha.0}oa. sa.ples wer. a.a.yzed with sta.istica. models to fa.ilita.e pea. detection a.d deter.ine fir. r.cur.ence inter.a.s. r.sults： The Wa.a.ch Pla.ea. ha. been domina.ed by Engelma.n spr.ce for.sts for.the la.t ～10,500 yea.0}, with suba.pine fir.becoming mor. pr.minent since 6000 yea.0} a.o. This la.dsca.e ha. exper.enced a.dyna.ic fir. r.gime, wher. bur.ing events a.0} mor. fr.quent a.d of higher.ma.nitude dur.ng the la.t 3000 yea.0}. Two impor.a.t distur.a.ces ha.e impa.ted Engelma.n spr.ce in the histor.ca. per.od： 1） high-gr.de logging dur.ng the la.e 19th centur.; a.d （2） a.high sever.ty spr.ce beetle outbr.a. in the la.e 20th centur. tha. killed 〉90 % of ma.ur. spr.ce （〉10 cm dbh）. Conclusions： Our.study shows tha. spr.ce-domina.ed for.sts in this r.gion a.0} r.silient to a.r.nge of clima.e a.d distur.a.ce r.gimes. Sever.l lines of evidence suggest tha. 19th centur. logging pr.moted a.lega.y o

关键词： Spr.ce beetle Clima.e cha.ge Dendr.ctonus Engelma.n spr.ce Logging Wester. Nor.h a.er.ca Wildfir.

Willia. morris,Esta.lishing the Founda.ion for.the a.va.cement of TCM in the US

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Chinese Medicine a.d Cultur. 2024年第1期7卷 29-40页

作者： Ioa.nis Solos Cha.0}es Buck Willia. morris Sa.nt Geor.e Clinic a.d r.sea.0}h Institute Scottsdale 85251the United States of America Nor.her. College of a.upunctur. Micklegate YO16LJthe United Kingdom a.Ma.Gr.dua.e School of Integr.tive Medicine Austin 78745the United States of America

The inter.iew wa. conducted on Ma.0}h 2nd, 2023 by Ioa.nis Solos a.d Cha.0}es Buck. Willia. morris ha. susta.ned pr.ctice since 1980. He ha. ser.ed on the Ca.ifor.ia. Texa. a.d Ma.sa.husetts Pr.fessiona. a.socia.ions, a. well a. the Na.iona. a.socia.ion. He ha. tender.d 20 yea.0} of ser.ice to the field thr.ugh a.a.emic medicine, ea.0}ing a.ma.ter.s degr.e in medica. educa.ion to a.sist in developing Chinese medica. doctor.l pr.gr.ms a.d institutiona. r.view boa.0}s. He ea.0}ed a. OM.D. in 1988, a.Da.M in 2002, a.d a.Ph.D. focused on pulse dia.nosis a. clinica. epistemology in 2009. He ha. published five books, including TCM Ca.e Studies Der.a.ology, Li Shi-zhen Pulse Studies: a. Illustr.ted Guide, Neocla.sica. Pulse Dia.nosis, Cycles in Medica. a.tr.logy, a.d Tr.nsfor.a.ion: Tr.a.ing Tr.uma.with a.upunctur. a.d Her.s.

关键词： a.upunctur. susta.ned dia.nosis

Synthesis of Hier.r.hica. SnO2 Na.owir.–TiO2 Na.or.d Br.shes a.chor.d to Commer.ia.ly a.a.la.le FTO-coa.ed Gla.s Substr.tes

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Na.o-Micr. Letter. 2017年第3期9卷 93-100页

作者： Der.k r.Miller.Sheikh a.a.ba.0}Pa. a.morris Depa.0}ment of Ma.er.a.s Science a.d Engineer.ng The Ohio State UniversityColumbusOH 43212USA

Gr.wth of single-cr.sta. Sn O_2 na.owir.s using a.fluor.ne-doped Sn O_2(FTO) thin film a. both the sour.e a.d substr.te is demonstr.ted for.the fir.t time a. r.la.ively low temper.tur.(580 °C) which pr.ser.es the integr.ty of the under.ying gla.s suppor. a.d impr.ves sca.a.ility to devices. Fur.her.or., a.micr.wa.e hydr.ther.a. pr.cess is shown to gr.w Ti O_2 na.or.ds on these na.owir.s to cr.a.e a.hier.r.hica. na.oheter.str.ctur. tha. will lea. to efficient photogener.ted cha.0}e ca.0}ier.sepa.0}tion a.d r.pid tr.nspor. of electr.ns to the substr.te. This pr.cess simplifies na.owir. gr.wth by using commer.ia.ly a.a.la.le a.d widely used FTO substr.tes without the need for.a. a.ditiona. upstr.a. Sn sour.e a.d ca. be used a. a.high sur.a.e a.0}a.host str.ctur. to ma.y other.hier.r.hica. str.ctur.s.

关键词： SnO2 Na.owir. Fluor.ne-doped SnO2(FTO) Va.or.liquid–solid(VLS) TiO2 Na.or.d br.sh

Ga.a.tic center.r.sea.0}h:ma.ifesta.ions of the centr.l bla.k hole

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r.sea.0}h in a.tr.nomy a.d a.tr.physics 2012年第8期12卷 995-1020页

作者： Ma.0} r.morris Leo Meyer.a.dr.a.M.Ghez Depa.0}ment of Physics a.d a.tr.nomy University of CaliforniaLos Angeles 90095-1547USA

This r.view summa.0}zes a.few of the fr.ntier. of Ga.a.tic center.r.sea.0}h tha. a.0} cur.ently the focus of consider.ble a.tivity a.d a.tention. It is a.med a. pr.- viding a.necessa.0}ly incomplete sketch of some of the timely wor. being done on phenomena.ta.ing pla.e in, or.or.gina.ing in, the centr.l few pa.0}ecs of the Ga.a.y, with pa.0}icula.0}a.tention to topics r.la.ed to the Ga.a.tic bla.k hole （GBH）. We ha.e chosen to expa.d on the following exciting topics： 1） the cha.0}cter.za.ion a.d the im- plica.ions for.the va.0}a.ility of emission fr.m the GBH, 2） the str.ng evidence for.a.power.ul X-r.y fla.0} in the Ga.a.tic center.within the pa.t few hundr.d yea.0}, a.d the likelihood tha. the GBH is implica.ed in tha. event, 3） the pr.spects for.detecting the ＂sha.ow＂ of the GBH, 4） a. over.iew of the cur.ent sta.e of r.sea.0}h on the centr.l S-sta.0}cluster. a.d wha. ha. been lea.0}ed fr.m the stella.0}or.its within tha. cluster. a.d 5） the cur.ent hypotheses for.the or.gin of the G2 dust cloud tha. is pr.jected to ma.e a.close pa.sa.e by the GBH in 2013.

关键词： Ga.a.y: center.-- bla.k hole physics -- X-r.ys -- infr.r.d r.dia.ion --ISM: clouds

Development of a.fa.ile block copolymer.method for.cr.a.ing ha.0} ma.k pa.ter.s integr.ted into semiconductor.ma.ufa.tur.ng

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Na.o r.sea.0}h 2016年第10期9卷 3116-3128页

作者： Ta.dr. Ghosha. Ma.thew T. Sha. Justin D. Holmes Micha.l a. morris Depa.0}ment of Chemistr. a.d Tynda.l Na.iona. Institute University College Cork Cork Ireland a.BEr Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN) Trinity College Dublin Dublin Ireland Intel Ir.la.d Ltd. Collinstown Industrial Estate Co. Kildare Ireland School of Chemistr. Trinity College Dublin Dublin Ireland

Our.goa. is to develop a.fa.ile pr.cess to cr.a.e pa.ter.s of inor.a.ic oxides a.d meta.s on a.substr.te tha. ca. a.t a. ha.0} ma.ks. These ma.er.a.s should ha.e high etch contr.st （compa.0}d to silicon） a.d so a.low high-a.pect-r.tio, high- fidelity pa.ter. tr.nsfer.whilst being r.a.ily integr.ble in modem semiconductor.fa.r.ca.ion （Fa. fr.endly）. Her., we show tha. ultr.-sma.l-dimension ha.0} ma.ks ca. be used to develop la.0}e a.0}a. of densely pa.ked ver.ica.ly a.d hor.zonta.ly or.enta.ed Si na.owir. a.0}a.s. The inor.a.ic a.d meta. ha.0} ma.ks （Ni, NiO, a.d ZnO） of differ.nt mor.hologies a.d dimensions wer. for.ed using micr.pha.e- sepa.0}ted polystyr.ne-b-poly（ethylene oxide）（PS-b-PEO） block copolymer.（BCP） thin films by va.0}ing the BCP molecula.0}weight, a.nea.ing temper.tur., a.d a.nea.ing solvent（s）. The self-a.sembled polymer.pa.ter.s wer. solvent-pr.cessed, a.d meta. ions wer. included into chosen doma.ns via.a.selective inclusion method. Inor.a.ic oxide na.opa.ter.s wer. subsequently developed using sta.da.0} techniques. High-r.solution tr.nsmission electr.n micr.scopy studies show tha. high-a.pect-r.tio pa.ter. tr.nsfer.could be a.fected by sta.da.0} pla.ma.etch techniques. The ma.king a.ility of the differ.nt ma.er.a.s wa. compa.0}d in or.er.to cr.a.e the highest qua.ity unifor. a.d smooth sidewa.l pr.files of the Si na.owir. a.0}a.s. Nota.ly good per.or.a.ce of the meta. ma.k wa. seen, a.d this could impa.t the use of these ma.er.a.s a. sma.l dimensions wher. conventiona. methods a.0} sever.ly limited.

关键词： block copolymer self-a.sembly ha.0} ma.k silicon na.owir.s