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Current Medical Science 2019年第6期39卷 890-898页

作者： Min ZHANG Chao WANG Hua-lin CAI Jing WEN ping-fei fang Department of Pharmacy the Second Xiangya HospitalCentral South UniversityChangsha 410011China Institute of Clinical Pharmacy Central South UniversityChangsha 410011China

Licorice,one of the most widely used medicinal herbs in East Asia,has effects such as anti-inflammation,antioxidant,and *** study aimed to evaluate the protective effect of licorice on brucine-induced *** Dawley rats were administered with brucine intraperitoneally for 7 consecutive days with or without treatment with *** content of blood urea nitrogen and creatinine in serum,the activities of superoxide dismutase and content of glutathione,malonaldehyde in kidney tissue were ***-eosin staining was employed to observe the histopathological changes of *** expression and phosphorylation levels of protein were evaluated by Western blotting and immunohistochemical *** results illustrated that treatment with licorice extracts(LE)significantly protected against the brucineinduced nephrotoxicity by reducing the content of blood urea nitrogen and serum creatinine,attenuating pathologic *** unbalance of oxidative stress was repaired by LE via increasing the level of glutathione,promoting the activities of superoxide dismutase and decreasing the content of *** addition,LE overturned the influence of brucine on apoptosis-related protein and signal transducer and activator of transcription-3(STAT3)*** together,these data demonstrate that licorice may attenuate brucine-induced nephrotoxicity via inactivation of oxidative stress and mitochondrial-mediated apoptosis *** importantly,the renoprotective effects may be mediated,at least partly,by preventing the activation of STAT3 protein.

关键词： licorice brucine nephrotoxicity apoptosis STAT3

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纳米碳酸钙驱铅研究

中国现代医学杂志 2015年第13期25卷 5-7页

作者：刘雨涛潘一峰黄彦凝方平飞肖平中南大学湘雅医院湖南长沙410008 中南大学湘雅二医院湖南长沙410011

目的比较不同粒径的碳酸钙的除铅效果。方法配制模拟小肠上端液,观测体外不同粒径碳酸钙的除铅效果;建立铅中毒动物模型,观测体内不同粒径碳酸钙的除铅效果;原子吸收光谱仪测定Pb2+浓度。结果不同粒径的碳酸钙在模拟肠液中均能降低铅离... 详细信息

目的比较不同粒径的碳酸钙的除铅效果。方法配制模拟小肠上端液,观测体外不同粒径碳酸钙的除铅效果;建立铅中毒动物模型,观测体内不同粒径碳酸钙的除铅效果;原子吸收光谱仪测定Pb2+浓度。结果不同粒径的碳酸钙在模拟肠液中均能降低铅离子浓度,并且除铅效果随着粒径减小而增强,小粒径的纳米碳酸钙A在6 h时,几乎全部去除铅离子。动物实验表明,纳米碳酸钙的除铅效果与常用口服驱铅药物二巯基丁二酸相同,优于微米碳酸钙。结论纳米碳酸钙具有成为新型无毒副作用驱铅药剂的潜力。

关键词：纳米碳酸钙体内、外驱铅

控制方向未知的受限多智能体系统的预设时间模糊控制

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工程科学学报 2025年第1期47卷 121-129页

作者：李菲周超范利蓉王芳燕山大学理学院秦皇岛066004 河北农业大学海洋学院秦皇岛066003

综合考虑受控制方向未知、输入受限和状态时延影响的有领导者多智能体系统的编队控制问题,设计基于模糊逻辑系统的预设时间一致性控制策略.为了保证编队输出误差在预设时间内满足预定的约束范围要求,引入预设时间性能函数,构造Lyapunov-... 详细信息

综合考虑受控制方向未知、输入受限和状态时延影响的有领导者多智能体系统的编队控制问题,设计基于模糊逻辑系统的预设时间一致性控制策略.为了保证编队输出误差在预设时间内满足预定的约束范围要求,引入预设时间性能函数,构造Lyapunov-Krasovskii(L-K)泛函解决状态时延问题,将外界干扰和L-K泛函的导数中的部分项定义为未知非线性函数,并利用模糊逻辑系统对其进行估计,利用Nussbaum函数和均值定理分别处理控制方向未知和输入受限问题,基于以上设计,提出预设时间模糊控制策略,并通过Lyapunov稳定性理论,分析闭环系统的有界稳定性,数值对比仿真和两级化学反应器应用仿真说明控制方法的有效性.

关键词：多智能体系统状态时延输出误差约束输入受限控制方向未知

Mechanism analysis of non-sinusoidal oscillation of continuous casting mold synchronously driven by double servomotors

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Journal of Iron and Steel Research International 2017年第3期24卷 251-257页

作者： Chao Zhou Xing-zhong Zhang fang Wang ping-fei Liu Yi-ming fang National Engineering Research Center for Equipment and Technology of Cold Strip Rolling Yanshan University Qinhuangdao 066004 Hebei China Hebei Agricultural University Qinhuangdao 066003 Hebei China School of Science Yanshan University Qinhuangdao 066004 Hebei China

Due to the disadvantages of complexity,high maintenance and vast investment of the electro-hydraulic servo oscillator,a new mechanical device synchronously driven by double servomotors was proposed. The working principle of the non-sinusoidal oscillator was analyzed and the model of the oscillator was validated via simulation ***,taking advantage of resonance technology,the hinging force and moment were calculated. The results showed that the hinging force and driving moment reduced,which was useful in reducing the impact of the hinge and prolonging the service life of the bearing. Besides,the best initial spring pressure was 0. 9 times the mold gravity,which improved the oscillation system stability and reduced the load fluctuation and servomotor driving power.

关键词： Continuous casting Mold Non-sinusoidal oscillation Resonance technology Oscillation mechanism

Structure and properties of indium-doped ZnO films prepared by RF magnetron sputtering under different pressures

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Rare Metals 2022年第9期41卷 3239-3243页

作者： Li-ping Peng A-Ling He Liang fang Xiao-fei Yang Research Center of Laser Fusion Chinese Academy of Engineering PhysicsMianyang621900China Department of Applied Physics Chongqing UniversityChongqing400030China Science and Technology Information Center Chinese Academy of Engineering PhysicsMianyang621900China

High conductive and transparent In-doped ZnO thin films were deposited on glass substrates by radio-frequency(RF)magnetron sputtering at 250℃.Argon gas was used as the sputtering gas,and its pressure varies from 0.1 to 4.0 *** influences of deposition pressure on the structural,electrical and optical properties of the films were investigated by means of X-ray diffraction(XRD),scanning electron microscope(SEM)and Hall and transmittance *** optical constant of the films was estimated from transmittance data using a nonlinear programming *** is found that the deposition pressure affects the properties of the films *** film deposited at 2.0 Pa shows the optimal crystal quality with a high transmittance of 85%in the visible range and a low resistivity of 2.4×10^(−3)Ω·cm and can thus be used as a transparent electrode.

关键词： ZnO thin films Transparent conductive oxide Optical constant Magnetron sputtering

New Families of Exact Excitations to （2＋1）-Dimensional Toda Lattice System via an Extended Projective Approach

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Communications in Theoretical Physics 2006年第5期45卷 864-868页

作者： fang Jian-ping fei Jin-Xi ZHENG Chun-Long College of Physics and Mathematics Lishui University Lishui 323000 China Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072China

In this paper, the extended projective approach, which was recently presented and successfully used in some continuous nonlinear physical systems, is generalized to nonlinear partial differential-difference systems （DDEs）, As a concrete example, new families of exact solutions to the （2＋1）-dimensional Toda lattice system are obtained by the extended projective approach.

关键词： extended projective approach DDEs Toda lattice exact solution

Impacts of the north migration of China＇s rice production on its ecosystem service value during the last three decades (1980-2014)

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Journal of Integrative Agriculture 2017年第1期16卷 76-84页

作者： fang Fu-ping FENG Jin-fei LI Feng-bo PENG Shao-bing Huazhong Agricultural University Wuhan 430070 P.R. China China National Rice Research Institute Hangzhou 310006 P.R. China

The ecosystem services value （ESV） of rice system has received increasing attention in agricultural policy decision. Over the last three decades, China＇s rice production presented an obviously trend that moving towards north locations. However, the impacts of this migration on the ESV of rice production have not been well documented. In this paper, we analyzed the change of the ESV of rice production in China under ＂north migration＂ and ＂no migration＂ scenarios during 1980-2014 based on long-term historical data. The results showed that both the positive and negative ESVs of rice production were lower under ＂north migration＂ than under ＂no migration＂ scenarios. The total ESV during 1980-2014 was reduced by 15.8%. ＂North migration＂ significantly reduced the area-scaled ESV since the early 1990s; while its impact on yield-scaled ESV was not significant. The effects of＂north migration＂ on ESV showed great spatial variation. The greatest reduction in total and area-scaled ESV was observed in south locations. While the yield-scaled ESVs of most south locations were enhanced under ＂north migration＂ scenario. These results indicated that ＂north migration＂ has generated adverse effects on the ESV of rice production. An adjustment in the spatial distribution is essential to protecting the non-production benefits of rice ecosystem.

关键词： ecosystem service value north migration rice ecosystem spatial variation historical change

Transferring entangled states of photonic cat-state qubits in circuit QED

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Frontiers of physics 2020年第2期15卷 27-37页

作者： Tong Liu Zhen-fei Zheng Yu Zhang Yu-Liang fang Chui-ping Yang Quantum Information Research Center Shangrao Normal UniversityShangrao 334001China Key Laboratory of Quantum Information University of Science and Technology of ChinaHeifei 230026China School of Physics Nanjing UniversityNanjing 210093China

We propose a method for transferring quantum entangled states of two photonic cat-state qubits(cqubits)from two microwave cavities to the other two microwave *** proposal is realized by using four microwave cavities coupled to a superconducting flux *** of using four cavities with different frequencies,the inter-cavity crosstalk is significantly *** only one coupler qutrit is used,the circuit resource is *** entanglement transfer is completed with a singlestep operation only,thus this proposal is quite *** third energy level of the coupler qutrit is not populated during the state transfer,therefore decoherence from the higher energy level is greatly *** numerical simulations show that high-fidelity transfer of two-cqubit entangled states from two transmission line resonators to the other two transmission line resonators is feasible with current circuit QED *** proposal is universal and can be applied to accomplish the same task in a wide range of physical systems,such as four microwave or optical cavities,which are coupled to a natural or artificial three-level atom.

关键词： transferring quantum entangled states photonic cat-state microwave cavities

The Uniqueness of Knieper Measure on Non-compact Rank 1 Manifolds of Non-positive Curvature

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Acta Mathematica Sinica,English Series 2021年第8期37卷 1219-1228页

作者： fei LIU fang WANG College of Mathematics and Systems Science Shandong University of Science and TechnologyQingdao 266590P.R.China School of Mathematical Sciences Capital Normal UniversityBeijing 100048P.R.China

We study the Knieper measures of the geodesic flows on non-compact rank 1 manifolds of non-positive *** construct the Busemann density on the ideal boundary,and prove that if there is a Knieper measure on T^(1)M with finite total mass,then the Knieper measure is unique,up to a scalar *** result partially extends Paulin-Pollicott-Shapira’s work on the uniqueness of finite Gibbs measure of geodesic flows on negatively curved non-compact manifolds to non-compact manifolds of non-positive curvature.

关键词： Geodesic flows Patterson-Sullivan measure Knieper measure

A Surgery Protocol for Adult Zebrafish Spinal Cord Injury

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Journal of Genetics and Genomics 2012年第9期39卷 481-487页

作者： ping fang Jin-fei Lin Hong-Chao Pan Yan-Qin Shen Melitta Schachner Center for Neuroscience Shantou University Medical College 22 Xinling Road Shantou 515041 China

Adult zebrafish has a remarkable capability to recover from spinal cord injury,providing an excellent model for studying neuro-regeneration. Here we list equipment and reagents,and give a detailed protocol for complete transection of the adult zebrafish spinal cord. In this protocol,potential problems and their solutions are described so that the zebrafish spinal cord injury model can be more easily and reproducibly *** addition,two assessments are introduced to monitor the success of the surgery and functional recovery：one test to assess free swimming capability and the other test to assess extent of neuroregeneration by in vivo anterograde axonal *** the swimming behavior test,successful complete spinal cord transection is monitored by the inability of zebrafish to swim freely for 1 week after spinal cord injury,followed by the gradual reacquisition of full locomotor ability within 6 weeks after *** a morphometric correlate,anterograde axonal tracing allows the investigator to monitor the ability of regenerated axons to cross the lesion site and increasingly extend into the gray and white matter with time after injury,confirming functional *** zebrafish model provides a paradigm for recovery from spinal cord injury,enabling the identification of pathways and components of neuroregeneration.

关键词： Zebrafish Spinal cord injury Surgery Locomotor recovery Axonal regrowth