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Rapid ongoing decline of Baird’s tapir in Cusuco National Park, Honduras

Integrative Zoology 2012年第4期7卷 420-428页

作者： Niall P.mcCANN phil m.wheeler Tim COLES michael W.BRUFORD School of Biosciences Cardiff UniversityCardiffUK Centre for Environmental and marine Sciences University of HullScarboroughUK Operation Wallacea Wallace HouseOld BolingbrokeUK

During the International Tapir Symposium 16-21 Oct 2011,the conservation of Baird's tapir(Tapirus baindi)in Honduras received a boost with the signing of a memorandum of understanding between the minister Direc-tor of the Honduran Instute of Conservation and Forestry(CF)and the Tapir Specialist Group(TSG)Despite this agreement,accelerating levels of hunting and habitat loss contimue to pose a threat to Baird's tapir in *** ongoing study in Cusuco National Park in northwestern Honduras has been monitoring changes in population dynamics of Baird's tapir since 2006 through the collection of occupancy *** study has iden-tified an increase in hunting pressure,coinciding with a drastic decline in the encounter rate with Baird's tapir ***,we examine the significance of a range of demographic variables on Baird's tapir occupancy in Cu-suco National Park using the software PRESENCE,and simulate the effects of different management strategies on the fiuture dynamics of the population using the stochastic simulation software VORTEX The predictions of the theoretical population models are compared to observed changes in occupancy *** found that non-intervention resulted in the local extinction of Baird's tapir within a very short time fiame,but that various in-tervention models enabled the population to recover to near carrying *** and extinction prob-ability were shown to respond marlkedly to the increase in hunting pressure;and occupancy models supported the fiuture population predictions generated by *** study suggests that immediate intervention is re-quired to reduce hunting pressure to near historical levels to prevent the imminent 1ocal extinction of the species.

关键词： Baird's tapir Honduras population viability analysis PRESENCE VORTEX

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Biorenewable materials for water remediation: The central role of cellulose in achieving sustainability

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Journal of Bioresources and Bioproducts 2024年第3期9卷 253-282页

作者： Kirti mishra Samarjeet Singh Siwal Thandiwe Sithole Nirankar Singh phil Hart Vijay Kumar Thakur Department of Chemistry M.M.Engineering CollegeMaharishi Markandeshwar(Deemed to be University)Haryana 133207India Department of Chemical Engineering University of JohannesburgDoornfontein 2088South Africa Biorefining and Advanced materials Research Center Scotland’s Rural CollegeEdinburgh EH93JGUnited Kingdom Renewable and Sustainable Energy Research Centre Technology Innovation InstituteAbu Dhabi 9639United Arab Emirates School of Engineering University of Petroleum&Energy StudiesDehradun 248007India

As the population increases and manufacturing grows,greenhouse gas and other harmful emissions *** with chemicals such as dyes,pesticides,pharmaceuticals,oil,heavy metals or radionuclides,wastewater purification has become an urgent *** technologies exist that can remove these contaminants from wastewater sources,but they often demand high energy and/or high cost,and in some cases produce contaminant laden sludge that requires safe *** need for methods which are less capital intensive,less operationally costly and more environmentally friendly is ***-based materials have emerged as promising candidates for wastewater treatment due to their renewability,low cost,biodegradability,hydrophilicity,and antimicrobial *** this review article,we focussed on developing sustainable and biodegradable cellulose-based materials for wastewater *** article deals with cellulose-based materials’scope and their conversion into valuable products like hydrogel,aerogel,cellulose composites,and *** cellulose-based materials have no harmful environmental impact and are *** modified cellulose-based materials applying as membrane,adsorbent,sorbent,and beads to purify the wastewater were ***,the challenges and future prospects of cellulose-based materials for wastewater treatment were considered,emphasizing their potential to be sustainable and eco-friendly alternatives to traditional materials used in wastewater treatment.

关键词： Cellulose Wastewater treatment Hydrogel Nanocrystal Cellulose membrane

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Data Traffic Reduction with Compressed Sensing in an AIoT System

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Computers, materials & Continua 2022年第1期70卷 1769-1780页

作者： Hye-min Kwon Seng-phil Hong mingoo Kang Jeongwook Seo Hanshin University Osan-si18101Korea Hancom with Inc. Seongnam-si13493Korea

To provide Artificial Intelligence(AI)services such as object detection,Internet of Things(IoT)sensor devices should be able to send a large amount of data such as images and ***,this inevitably causes IoT networks to be severely *** this paper,therefore,we propose a novel onem2m-compliant Artificial Intelligence of Things(AIoT)system for reducing overall data traffic and offering object *** consists of some IoT sensor devices with random sampling functions controlled by a compressed sensing(CS)rate,an IoT edge gateway with CS recovery and domain transform functions related to compressed sensing,and a YOLOv5 deep learning function for object detection,and an IoT *** analyzing the effects of compressed sensing on data traffic reduction in terms of data rate per IoT sensor device,we showed that the proposed AIoT system can reduce the overall data traffic by changing compressed sensing rates of random sampling functions in IoT sensor *** addition,we analyzed the effects of the compressed sensing on YOLOv5 object detection in terms of performance metrics such as recall,precision,mAP50,and mAP,and found that recall slightly decreases but precision remains almost constant even though the compressed sensing rate decreases and that mAP50 and mAP are gradually degraded according to the decreased compressed sensing ***,if proper compressed sensing rates are chosen,the proposed AIoT system will reduce the overall data traffic without significant performance degradation of YOLOv5.

关键词： 5G Internet of Things data traffic compressed sensing YOLOv5

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Comparative Transcriptomic Profiling of Vitis vinifera Under High Light Using a Custom-made Array and the Affymetrix GeneChip

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molecular Plant 2011年第6期4卷 1038-1051页

作者： Luisa C. Carvalho Belmiro J. Vilela phil m. mullineaux Sara Amancio CBAA Instituto Superior de Agronomia Universidade Tecnica de Lisboa Tapada da Ajuda 1349-017 Lisboa Portugal DDSB John Innes Centre Colney Norwich NR4 7UH UK Department of Biological Sciences University of Essex Colchester CO4 3SQ UK

Understanding abiotic stress responses is one of the most important issues in plant research nowadays. Abiotic stress, including excess light, can promote the onset of oxidative stress through the accumulation of reactive oxygen species. Oxidative stress also arises when in vitro propagated plants are exposed to high light upon transfer to ex vitro. To determine whether the underlying pathways activated at the transfer of in vitro grapevine to ex vitro conditions reflect the processes occurring upon light stress, we used Vitis vinifera Affymetrix GeneChip （VvGA） and a custom array of genes responsive to light stress （LSCA） detected by real-time reverse transcriptase PCR （qRT-PCR）. When gene-expression profiles were compared, ＇protein metabolism and modification＇, ＇signaling＇, and ＇anti-oxidative＂ genes were more represented in LSCA, while, in VvGA, ＇cell wall metabolism＇ and ＇secondary metabolism＇ were the categories in which gene expression varied more significantly. The above functional categories confirm previous studies involving other types of abiotic stresses, enhancing the common attributes of abiotic stress defense pathways. The LSCA analysis of our experimental system detected strong response of heat shock genes, particularly the protein rescuing mechanism involving the cooperation of two ATP-dependent chaperone systems, Hsp100 and Hsp70, which showed an unusually late response during the recovery period, of extreme relevance to remove non-functional, potentially harmful polypeptides arising from misfolding, denaturation, or aggregation brought about by stress. The success of LSCA also proves the feasibility of a custommade qRT-PCR approach, particularly for species for which no GeneChip is available and for researchers dealing with a specific and focused problem.

关键词： Quantitative real-time PCR Vitis vinifera GeneChip light stress Heat Shock Proteins oxidative and photooxidative stress.

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Tooth loss and alveolar remodeling in Sinosaurus triassicus (Dinosauria: Theropoda) from the Lower Jurassic strata of the Lufeng Basin, China

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Chinese Science Bulletin 2013年第16期58卷 1931-1935页

作者： XING LiDa BELL phil R ROTHSCHILD Bruce m RAN Hao ZHANG JianPing DONG Zhiming ZHANG Wei CURRIE philip J Department of Biological Sciences University of Alberta School of the Earth Sciences and Resources China University of Geosciences Pipestone Creek Dinosaur Initiative Division of Vertebrate Paleontology Natural History Museum and Biodiversity Research Institute University of Kansas Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Guangxi Normal University) Ministry of Education Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences Department of Computer Engineering Chengdu Electromechanical College

Pathological or traumatic loss of teeth often results in the resorption and remodeling of the affected alveoli in mammals. However, instances of alveolar remodeling in reptiles are rare. A remodeled alveolus in the maxilla of the Chinese theropod Sinosaurus (Lower Jurassic Lower Lufeng Formation) is the first confirmed example of such dental pathology in a dinosaur. Given the known relationship between feeding behavior and tooth damage in theropods (teeth with spalled enamel, tooth crowns embedded in bone) and the absence of dentary, maxillary, and premaxillary osteomyelitis, traumatic loss of a tooth is most likely the cause of alveolar remodeling. Based on the extent of remodeling, the injury and subsequent tooth loss were non-fatal in this individual.

关键词：下侏罗统兽脚类牙齿肺泡中国恐龙禄丰盆地地层

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An AIoT monitoring System for multi-Object Tracking and Alerting

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Computers, materials & Continua 2021年第4期67卷 337-348页

作者： Wonseok Jung Se-Han Kim Seng-phil Hong Jeongwook Seo Korea Electronics Technology Institute Seongnam13509Korea Electronics and Telecommunications Research Institute Daejeon34129Korea Hancom With Inc. Seongnam13493Korea Hanshin University Osan-si18101Korea

Pig farmers want to have an effective solution for automatically detecting and tracking multiple pigs and alerting their conditions in order to recognize disease risk factors *** this paper,therefore,we propose a novel monitoring system using an Artificial Intelligence of Things(AIoT)technique combining artificial intelligence and Internet of Things(IoT).The proposed system consists of AIoT edge devices and a central monitoring ***,an AIoT edge device extracts video frame images from a CCTV camera installed in a pig pen by a frame extraction method,detects multiple pigs in the images by a faster region-based convolutional neural network(RCNN)model,and tracks them by an object center-point tracking algorithm(OCTA)based on bounding box regression outputs of the faster ***,it sends multi-pig tracking images to the central monitoring server,which alerts them to pig farmers through a social networking service(SNS)agent in cooperation with an onem2m-compliant IoT alerting *** results showed that the multi-pig tracking method achieved the multi-object tracking accuracy performance of about 77%.In addition,we verified alerting operation by confirming the images received in the SNS smartphone application.

关键词： Internet of Things multi-object tracking pig pen social network

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Genetic Analysis of ele mutants and Comparative mapping of ele1 Locus in the Control of Organ Internal Asymmetry in Garden Pea

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Journal of Integrative Plant Biology 2010年第6期52卷 528-535页

作者： Xin Li Li-Li Zhuang mike Ambrose m. phil. Catherine Rameau Xiao-He Hu Jun Yana Da Luo School of Life Science and Biotechnology Shanghai JiaoTong University Shanghai 200030 China Department of Crop Genetics John Innes Centre Colney Norwich NR4 7UH United Kingdom Station de Genetique et d'Amelioration des Plantes Institut J.P. Bourgin UR 254 INRA Versailles France National Key Laboratory of Plant molecular Genetics Institute of Plant Physiology and Ecology Shanghai Institutes for Biologica Sciences the Chinese Academy of Sciences Shanghai 200032 China

Previous study has shown that during zygomorphic development in garden pea （Pisum sativum L.）, the organ internal （IN） asymmetry of lateral and ventral petals was regulated by a genetic locus, SYmmETRIC PETAL 1 （SYP1）, while the dorsoventral （DV） asymmetry was determined by two CYC-like TCP genes or the PsCYC genes, KEELED WINGS （K） and LOBED STANDARD 1 （LST1）. In this study, two novel loci, ELEPHANT EAR-LIKE LEAF 1 （ELE1） and ELE2 were characterized. These mutants exhibit a similar defect of IN asymmetry as syp1 in lateral and ventral petals, but also display pleiotropic effects of enlarged organ size. Genetic analysis showed that ELE1 and ELE2 were involved in same genetic pathway and the enlarged size of petals but not compound leaves in e/e2 was suppressed by introducing k and Ist1, indicating that the enlargement of dorsal petal in e/e2 requires the activities of K and LST1. An experimental framework of comparative genomic mapping approach was set up to map and clone LjELE1 locus in Lotus japonicus. Cloning the ELE1 gene will shed light on the underlying molecular mechanism during zygomorphic development and further provide the molecular basis for genetic improvement on legume crops.

关键词： Viverridae Genetics Organizations Corolla Loci

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multi-national observational study to assess quality of life and treatment preferences in patients with Crohn’s perianal fistulas

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World Journal of Gastrointestinal Surgery 2023年第11期15卷 2537-2552页

作者： Chitra Karki Amod Athavale Vijay Abilash Gary Hantsbarger Parnia Geransar Kate Lee Slobodan milicevic marko Perovic Leanne Raven magdalena Sajak-Szczerba Abigail Silber Annabelle Yoon phil Tozer Global Evidence and Outcomes-Gastroenterology Takeda Pharmaceuticals United StatesIncCambridgeMA 02139United States Trinity Partners LLCWalthamMA 02451-7528United States Observational Research Takeda Pharmaceuticals United StatesIncCambridgeMA 02139United States medical Affairs Takeda Pharmaceuticals International Co.Opfikon 8152ZurichSwitzerland Research and Patient Programs Crohn’s and Colitis Canada600-60 St.Clair Avenue EastToronto M4T 1N5OntarioCanada Treasurer European Federation of Crohn’s&Ulcerative Colitis AssociationsBrussels B 1000Belgium Crohn’s and Colitis Australia Camberwell SouthVIC 3124Australia European Federation of Crohn’s&Ulcerative Colitis Associations Brussels B 1000Belgium Japan medical Office Takeda Pharmaceutical Company LimitedTokyo 103-8668Japan Department of Colorectal Surgery St Mark’s Hospital and Academic InstituteLondon HA13UJUnited Kingdom

BACKGROUND Patients with Crohn’s disease(CD)are at risk of developing complications such as perianal *** with Crohn’s perianal fistulas(CPF)are affected by fecal incontinence(FI),bleeding,pain,swelling,and purulent perianal discharge,and mETHODS This cross-sectional observational study was conducted in patients with CD aged 21-90 years via a web-enabled questionnaire in seven countries(April-August 2021).Patients were recruited into three cohorts:Cohort 1 included patients without perianal fistulas;cohort 2 included patients with perianal fistulas without fistula-related surgery;and cohort 3 included patients with perianal fistulas and fistula-related *** patient-reported outcome measures were used to assess quality of *** of treatment preferences were measured using a discrete choice experiment(DCE).RESULTS In total,929 patients were recruited(cohort 1,n=620;cohort 2,n=174;cohort 3,n=135).Short Inflammatory Bowel Disease Questionnaire scores were worse for patients with CPF(cohorts 2 and 3)than for those with CD without CPF(cohort 1):mean score 3.8 and 3.7 vs 4.1,respectively,(Pmilarly,mean Revised FI and FI Quality of Life scores were worse for patients with CPF than for those with CD without *** of Life with Anal Fistula scores were similar in patients with CPF with or without CPF-related surgery(cohorts 2 and 3):mean score 41 and 42,*** the DCE,postoperative discomfort and fistula healing rate were the most important treatment attributes influencing treatment choice:mean relative importance 35.7 and 24.7,*** The burden of illness in CD is significantly higher for patients with CPF and patients rate lower postoperative discomfort and higher healing rates as the most desirable treatment attributes.

关键词： Burden of illness Crohn’s disease Discrete choice experiment Perianal fistulas Patient-reported outcomes Treatment preferences

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Does Haptoglobin Phenotype Impact Infection mortality?

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Advances in Biological Chemistry 2022年第5期12卷 143-150页

作者： Akissi Joelle Koffi Hugues Thierno Ahiboh philémond By Delphine Gabillard Roseline Affi Francisk Kouakou André Inwoley Département de Biochimie et Biologie moléculaire UFR SPB Université Félix Houphouet Boigny Ivory Coast

Introduction: The physiological status of a subject and the pathophysiology in some diseases might be under the influence of haptoglobin phenotype. The objective of this work was to determine the relationship between mortality from HIV/AIDS infection and haptoglobin phenotype in a black population in Côte d’Ivoire. methods: The study was conducted from a retrospective panel of 933 sera/plasma from the previous workup of the ANRS 12136 TEmPRANO trial at month 0 of patients in deferred-ART arms. For each subject, we determined the serum haptoglobin concentration, haptoglobin phenotype, and other variables from patient files from the TEmPRANO trial database. Statistical tests used were Chi-2, Fischer, and Kruskal-Wallis tests for non-gaussian distribution. We used the Kaplan-meier method for survival analysis. Results: The distributions of the haptoglobin phenotypes were 32.3% for Hp 1-1, 39.5% for Hp 2-1 and 27.2% for Hp 2-2. The blood haptoglobin concentration seemed to be associated with haptoglobin phenotypes (p-value > 5%). The survival rate at m30 and for an extended follow-up up to 6 years was independent of haptoglobin phenotype (p-value > 5%). Besides, the haptoglobin phenotypes do not appear to be associated with CD4+ T-cell count and with hemoglobin concentration. Conclusion: Haptoglobin phenotype seems to not impact the mortality of HIV/AIDS infection. However, given the antioxidant and immunomodulatory properties of some haptoglobin phenotypes, it would be relevant to seek out possible confounding factors indirectly associated with haptoglobin phenotypes and clinical or biological infection variables.

关键词： HIV/AIDS Infection Phenotype of Haptoglobin CD4+ Cell Counts Hemoglobin mortality

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In vivo and ex vivo confocal endomicroscopy of pancreatic cystic lesions: A prospective study

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World Journal of Gastroenterology 2017年第18期23卷 3338-3348页

作者： Somashekar G Krishna Rohan m modi Amrit K Kamboj Benjamin J Swanson phil A Hart mary E Dillhoff Andrei manilchuk Carl R Schmidt Darwin L Conwell Division of Gastroenterology Hepatology and NutritionThe Ohio State University Wexner Medical Center Department of Internal medicine The Ohio State University Wexner Medical Center College of medicine The Ohio State University Wexner Medical Center Department of Pathology The Ohio State University Wexner Medical Center Division of Surgical Oncology The Ohio State University Wexner Medical Center Deparment of General Surgery The Ohio State University Wexner Medical Center

AIm To investigate the reproducibility of the in vivo endoscopic ultrasound(EUS)-guided needle based confocal endomicroscopy(n CLE) image patterns in an ex vivo setting and compare these to surgical histopathology for characterizing pancreatic cystic lesions(PCLs). mETHODS In a prospective study evaluating EUS-nC LE for evaluation of PCLs, 10 subjects underwent an in vivo nC LE(AQFlex nC LE miniprobe; Cellvizio, maunaK ea, Paris, France) during EUS and ex vivo probe based CLE(pC LE) of the PCL(Gastroflex ultrahigh definition probe, Cellvizio) after surgical resection. Biopsies were obtained from ex vivo CLE-imaged areas for comparative histopathology. All subjects received intravenous fluorescein prior to EUS and pancreatic surgery for in vivo and ex vivo CLE imaging respectively. RESULTS A total of 10 subjects(mean age 53 ± 12 years; 5 female) with a mean PCL size of 34.8 ± 14.3 mm were enrolled. Surgical histopathology confirmed 2 intraductal papillary mucinous neoplasms(IPmNs), 3 mucinous cystic neoplasms(mCNs), 2 cystic neuroendocrine tumors(cystic-NETs), 1 serous cystadenoma(SCA), and 2 squamous lined PCLs. Characteristic in vivo nC LE image patterns included papillary projections for IPmNs, horizon-type epithelial bands for mCNs, nests and trabeculae of cells for cystic-NETs, and a "fern pattern" of vascularity for SCA. Identical image patterns were observed during ex vivo pC LE imaging of the surgically resected PCLs. Both in vivo and ex vivo CLE imaging findings correlated with surgical *** In vivo n CLE patterns are reproducible in ex vivo p CLE for all major neoplastic PCLs. These findings add further support the application of EUS-nC LE as an imaging biomarker in the diagnosis of PCLs.

关键词：共焦的激光 endomicroscopy 浆液的 cystadenoma 胰腺的 neuroendocrine 肿瘤 Intraductal 乳突的 mucinous 瘤胰腺的膀胱的瘤

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