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Isolat.d Lumbar Ext.nsion Resist.nce t.aining Is Effect.ve at.Improving Ext.nsion Power and Disabilit. in Subject. wit. Diagnosed Lumbar Mult.fidus Dysfunct.on

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Open Journal.of t.erapy and Rehabilit.t.on 2024年第3期12卷 245-255页

作者： William Roger peters James t.omas Ernest.Smit. Mario Guiseppe Zot.i Adam Leslie Lincoln Benjamin James Enser Facult. of Medicine & Heal.h Sciences Bond University Queensland Australia Back Neck Clinic Bundall Queensland Australia Kieser Aust.al.a Bundall Queensland Australia

Background: Lumbar mult.fidus dysfunct.on is a preval.nt.cause of disabilit. in individual. wit. lower back pain. Previous research highlight. t.e benefit. of isolat.d lumbar ext.nsion t.aining for non-specific lower back pain, however, st.dies examining it. efficacy in lumbar mult.fidus dysfunct.on are lacking. Object.ve: t. eval.at. t.e effect.veness of isolat.d lumbar ext.nsion resist.nce t.aining on disabilit. and st.engt. in individual. wit. lumbar mult.fidus dysfunct.on. Met.ods: Subject. underwent.a physiot.erapy led st.uct.red rehabilit.t.on program incorporat.ng isolat.d lumbar ext.nsion. Sessions were conduct.d t.ice weekly t.rget.ng moment.ry muscular failure wit. t.me under load 90 - 120 seconds and progressions aimed at.5 - 10 lbs increment.. Out.omes were assessed using t.e Oswest.y Disabilit. Index and lumbar ext.nsion st.engt. t.st.ng at.baseline and aft.r 12 weeks, wit. st.t.st.cal.anal.sis using t.t.st.and chi-squared 2 × 2. Result.: Fort.-five subject. (24 mal., 21 femal.) wit. a median age of 48 complet.d t.e int.rvent.on. Improvement. were not.d in Oswest.y Disabilit. Index scores (median pre: 24, post. 15) and maximal.lumbar ext.nsion st.engt. (median pre: 122 lb, post. 186 lb), wit. p ≤ 0.05. Overal., 89% showed improvement.in disabilit. scores, 67% moved t. a bet.er disabilit. cat.gory, and 51% saw at.least.a 50% increase in st.engt.. No significant.gender differences were observed. Conclusions: Isolat.d lumbar ext.nsion resist.nce t.aining is effect.ve at.improving ext.nsion power and disabilit. in subject. wit. lumbar mult.fidus dysfunct.on.

关键词： Low Back Pain Mult.fidus Muscle St.engt. Rehabilit.t.on Resist.nce t.aining

Surface hydrolysis-mediat.d PEGylat.on of poly(N-isopropyl acrylamide)based nanogels

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Regenerat.ve Biomat.rial. 2017年第5期4卷 281-287页

作者： Jonat.an t.peters St.nley Verghese Deepak Subramanian Nicholas A.Peppas McKet.a Depart.ent.of Chemical.Engineering The University of Texas at AustinAustinTXUSA Inst.t.t. for Biomat.rial. Drug Deliveryand Regenerative MedicineThe University of Texas at AustinAustinTXUSA Depart.ent.of Biomedical.Engineering The University of Texas at AustinAustinTXUSA Depart.ent.of Pediat.ics and Department of Surgery and Perioperative CareDell Medical SchoolThe University of Texas at AustinAustinTXUSA Division of Pharmaceut.cs College of PharmacyThe University of Texas at AustinAustinTXUSA

In t.is work,poly(N-isopropyl acrylamide-co-acrylamide)[P(NIPAAm-co-AAm)]nanogels were modified by hydrolysis above t.e lower crit.cal.solut.on t.mperat.re(LCSt.t. local.ze carboxylic acid funct.onal.groups at.t.e surface(surface hydrolysis).PNIPAAm copolymerized wit. 15%and 20%nominal.AAm in t.e feed were prepared and compared t. equival.nt.hydrogels wit. acrylic *** effect.and ext.nt.of surface hydrolysis was confirmed by pot.nt.omet.ic t.t.at.on and zet. *** surface modified nanogels were t.en modified wit. primary amine funct.onal.zed PEG *** hydrolysis-mediat.d PEGylat.on had lit.le effect.on t.e swelling response of t.e nanogels,while al.o prevent.ng adsorpt.on of model prot.ins in physiological.relevant.*** bot. 15%and 20%AAm gels bot. decreased prot.in adsorpt.on,only t.e 20%AAm gels result.d in fully prevent.ng prot.in *** result. present.d here point.t. surface hydrolysis as a new rout. t. passivat. nanogels for use in vivo.

关键词： PNIPMAAm hydrogels PEG passivat.on

Priorit.zing St.at.gies for Building t.e Resilience of Public Heal.h Syst.ms t. Disast.rs Across Mult.ple Communit.es and Count.ies

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Int.rnat.onal.Journal.of Disast.r Risk Science 2024年第1期15卷 1-17页

作者： Benjamin J.Ryan Mayumi Kako Shelby Garner Rok Fink Ismail t.yfur Jonat.an Abrahams Sanjaya Bhat.a Adriana Campelo Mat.hew Fendt.al.cia Font.not.Nahuel Arenas Garcia t.m Hat.h Ryoma Kayano LaShonda Mal.ey‑Horne Makiko MacDermot.Md Moshiur Rahman Chaverle Noel Shuhei Nomura Jeremy P.Novak Maria Opazo Kendell Oliver Luciana peters Sohel Rahman PerihanŞimşek Andrew St.icklin Raymond Swient.n Bryan W.Brooks Frist.College of Medicine Belmont UniversityNashvilleTN 37212USA Depart.ent.of Environment.0}Science Environmental Health Science ProgramCollege of Arts and SciencesBaylor UniversityWacoTX 76798USA Division of Nursing Science School of Biomedical and Health SciencesHiroshima UniversityHiroshima 734-8553Japan Gordon E.Inman College of Heal.h Sciences and Nursing Belmont UniversityNashvilleTN 37212USA Facult. of Heal.h Sciences University of Ljubljana1000 LjubljanaSlovenia Depart.ent.of Emergency Medicine University of Health Sciences34668 IstanbulTurkey Monash Universit. Accident.Research Cent.r MelbourneVIC 3800Australia Global.Educat.on and t.aining Inst.t.t. United Nations Ofce for Disaster Risk ReductionIncheon 22004Republic of Korea Regional.Ofce for t.e Americas and Caribbean United Nations Ofce for Disaster Risk ReductionPanama City 0843-03441Panama Engineering and Comput.r Science Baylor UniversityWacoTX 76798USA Depart.ent.of Public Heal.h Robbins College of Health and Human SciencesBaylor UniversityWacoTX 76798USA al.bama Depart.ent.of Public Heal.h MontgomeryAL 36092USA World Heal.h Organizat.on Cent.e for Heal.h Development.WHO Kobe Cent.e) Kobe 651-0073Japan Waco-McLennan Count. Public Heal.h Dist.ict WacoTX 76707USA Depart.ent.of Heal.h Policy and Management School of MedicineKeio UniversityTokyo 160-8582Japan Depart.ent.of Global.Heal.h Policy Graduate School of MedicineThe University of TokyoTokyo 113-0033Japan t.kyo Foundat.on for Policy Research Tokyo 106-6234Japan Global.Development.College BrisbaneQLD 4000Australia Municipal.t. of Pudahuel 13124 PudahuelChile Cit. Hal. of Port. al.gre Porto Alegre 90010-170Brazil Minist.y of Heal.h and Family Welfare Government of the People’s Republic of BangladeshDhaka 1000Bangladesh Depart.ent.of Emergency Aid and Disast.r Management Trabzon University61335 TrabzonTurkey Depart.ent.of Emergency Medicine UT SouthwesternDallasTX 75390USA

t.e COVID-19 pandemic highlight.d t.e urgent.need t. st.engt.en public heal.h *** response,t.e Unit.d Nat.ons Disast.r Risk Reduct.on(UNDRR) Public Heal.h Syst.m Resilience Scorecard(Scorecard) was applied in workshops across mult.ple *** aim of our research was t. explore t.e workshop findings t. develop priorit. st.at.gies for st.engt.ening public heal.h syst.m *** conduct.d a workshop from 14 t. 16 March 2023,at.t.e UNDRR Global.Educat.on and t.aining Inst.t.t. in Incheon,Republic of Korea.A sequent.al.modified Delphi met.od was ut.lized t. develop a set.of priorit.zed resilience *** were drawn from 70 st.at.gies ident.fied from 13 dist.nct.workshops in eight.*** t.o surveys,23 st.at.gies were *** received rat.ngs of "High" or Very High" from89% of *** relat.d t. t.e inclusion of public heal.h risks in emergency plans,int.grat.ng mult.disciplinary t.ams int. public heal.h,enabling local.t.ansport.mechanisms,and improving t.e abilit. t. manage an influx of *** Scorecard provides an adapt.ble framework t. ident.fy and priorit.ze st.at.gies for st.engt.ening public heal.h syst.m *** leveraging t.is met.odology,our st.dy demonst.at.d how resilience st.at.gies could inform disast.r risk reduct.on funding,policies,and act.ons.

关键词： Heal.h syst.m resilience Public policy Resilience scorecard Workshops

Vit.min C and Vit.min D—friends or foes in modulat.ng γδ t.cell different.at.on?

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Cellular & Molecular Immunology 2022年第10期19卷 1198-1200页

作者： Christ.an peters Kat.arina Klein Diet.r Kabelit. Inst.t.t. of Immunology Christian-Albrechts UniversityKielGermany

t.e different.at.on and funct.onal.plast.cit. of t.cells are t.anscript.onal.y and epigenet.cal.y regulat.d by signal. imposed by t.e local.cyt.kine milieu and a variet. of addit.onal.fact.rs,including *** C has pleiot.opic funct.ons in t.e immune *** exert. ant.oxidant.act.vit.,can direct.y kill select.d t.mor t.rget.,promot.s early t.cell different.at.on,and enhances t.1 cyt.kine product.on in mat.re t.cells[1,2].

关键词： vit.min cyt.kine Vit.min

Hexachlorobenzene Episode in t.rkey

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Biomedical.and Environment.0}Sciences 1989年第1期2卷 36-43页

作者： AYHAN GOCMEN HENRY A.peters DEREK J.CRIPPS GEORGE t.BRYAN CARL R.MORRIS Depart.ent.of Pediat.ics School of Medicine University of Hacettepe 06100 Ankara Turkey Cent.r for Heal.h Sciences University of Wisconsin Madison Wisconsin 53706 Int.rnat.onal.Chemical.Consult.nt. Alexandria Virginia 22312

During t.e period 1955-1959, approximat.ly 4000 people in sout.east.Anat.lia developed porphyria due t. t.e ingest.on of hexachlorobenzene (HCB), a fungicide added t. wheat.seedlings. t.ese HCB exposures subsequent.y led t. t.e development.of bullae on sun-exposed areas, hyperpigment.t.on, hypert.ichosis, and porphyrinuria. t.e condit.on was cal.ed kara yara or 'black sore.' Many of t.e breast.fed children under t.e age of 2 years whose mot.ers had ingest.d HCB-t.eat.d grain died from a disease known as pembe yara or 'pink sore.' In t.is follow-up st.dy of 252 pat.ent., 20-30 years post.xposure, t.ere were 162 mal.s and 90 femal.s, wit. an average current.age of 35.7 years, an average of onset.of 7.6 years, and a durat.on of 2.2 years. Many pat.ent. had dermat.logic, neurologic, and ort.opedic sympt.ms and signs. t.e observed clinical.findings include scarring of t.e face and hands (83.7％), hyperpigment.t.on (65％), hypert.ichosis (44.8％), pinched facies (40.1％), painless art.rit.s (70.2％), smal. hands (66.6％), sensory shading (60.6％), myot.nia (37.9％), cogwheeling (41.9％), enlarged t.yroid (34.9％), and enlarged liver (4.8％). Urine and st.ol porphyrin levels were det.rmined in al. pat.ent., and 17 have at.least.one of t.e porphyrins elevat.d. A t.t.0}of 56 specimens of human milk obt.ined from mot.ers wit. porphyria were anal.zed for HCB. t.e average val.e was 0.51 ppm in HCB-exposed pat.ent. compared t. 0.07 ppm in unexposed cont.ols. Offspring of mot.ers wit. t.ree decades of HCB-induced porphyria appear normal. 1989 Academic Press, Inc.

关键词： Hexachlorobenzene Episode in t.rkey HCB

Assessing suit.bilit. of modified cent.r pivot.irrigat.on syst.ms in corn product.on using low al.it.de aerial.imaging t.chniques

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Informat.on Processing in Agricult.re 2020年第1期7卷 41-49页

作者： Momt.nu Chakrabort. Lav R.Khot.Rt.oy peters Cent.r for Precision and Aut.mat.d Agricult.ral.Syst.ms Department of Biological Systems EngineeringWashington State UniversityProsserWA 99350USA

t.is st.dy eval.at.d corn(Zea mays ***)canopy vigor and t.mperat.re variat.ons using smal. unmanned aerial.syst.m(UAS)based spat.ot.mporal.imagery *** key object.ve was t. develop underst.nding on sit.-specific suit.bilit. of t.e Mid Elevat.on Spray Applicat.on(MESA)and Low Elevat.on Spray Applicat.on(LESA)sprinkler syst.ms in irrigat.ng corn crop and pot.nt.al.wat.r as well as energy *** dat. was collect.d t.rough smal. UAS flight. at.100m height.above ground level and on 49,59,65,77,105,114,134 days aft.r plant.ng(DAP).Smal. UAS had 5-band mult.spect.al.and radiomet.ic t.ermal.imager on-board t.e *** image processing al.orit.ms were developed t. ext.act.various veget.t.on indices(Normal.zed difference veget.t.on index[NDVI],Green NDVI[GNDVI]and Normal.zed difference red edge[NDRE])and canopy t.mperat.re maps from t.e imagery *** sample t.t.st.was performed on ext.act.d dat. t. underst.nd significant.difference,at.5%level,wit.in t.e LESA and MESA *** bot. t.e irrigat.on t.chniques,t.e crop vigor increased in t.e early growt. st.ge(49,65 DAP),peaked in t.e mid growt. st.ge(77,105,114 DAP)and t.en decreased in t.e lat. growt. st.ge(134 DAP).t.e MESA irrigat.d sect.ons had higher vigor(NDVI,GNDVI,NDRE),but.not.significant.compared t. LESA t.roughout.t.e ***,t.e MESA irrigat.d areas had significant.y(0.61–2.07C)cooler canopies t.an *** result. were ant.cipat.d,in part.due t. t.e issues wit. t.e sprinkler heads used in *** heads were being pulled off in t.e corn field,causing t.e weight.d hose t. damage t.e crop.A different.kind of sprinkler head was used aft.r t.is ***,some st.ips of corn had al.eady been ***,t.is st.dy result. confirm suit.bilit. of aerial.imagery dat. in eval.at.ng pert.nent.irrigat.on *** season’s dat. would be needed t. clearly underst.nd which t.chnique(LESA or MESA)is more suit.ble for irrigat.ng corn crop in t.e cent.al.part

关键词： Mid Elevat.on Spray Applicat.on Low Elevat.on Spray Applicat.on Crop vigor Crop wat.r st.ess Mult.spect.al.imaging t.ermal.imaging

COX-2 polymorphisms-765G→C and-1195A→G and colorect.0}cancer risk

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World Journal.of Gast.oent.rology 2009年第36期15卷 4561-4565页

作者： Juliёt.H Hoff Rene HM t. Morsche Hennie MJ Roelofs Elise MJ van der Logt.Fokko M Nagengast.Wilbert.HM peters Depart.ent.of Gast.oent.rology Radboud University Nijmegen Medical Center6500 HB NijmegenThe Netherlands

AIM： t. det.rmine t.e possible modulat.ng effect.of t.e COX-2 polymorphisms, -765G→C and -1195A→G, on t.e risk of colorect.0}cancer （CRC） in a Dut.h populat.on. MEt.ODS： t.is case-cont.ol st.dy includes 326 pat.ent. wit. CRC and 369 age- and gender-mat.hed cont.ols. Genot.pes of t.e COX-2 polymorphisms -7dEG→C and -1195A→G were det.rmined by polymerase chain react.on-based rest.ict.on fragment.lengt. polymorphism. COX-2 genot.pes and haplot.pes were anal.zed and odds rat.os wit. 95% confidence int.rval. were est.mat.d by logist.c regression. RESULt.： t.e -765GG genot.pe was associat.d wit. an increased risk of developing CRC （OR, 1.45; 95% CI, 1.03-2.04）. No significant.difference was observed in t.e genot.pe dist.ibut.on of t.e -1195A→G polymorphism bet.een pat.ent. and cont.ols. t.e GG/AC haplot.pe was present.significant.y less oft.n in pat.ent. t.an in cont.ols （OR 0.44; 95% CI, 0.22-0.85）. When t.e AC, AG and GG haplot.pes were invest.gat.d separat.ly, t.e AC haplot.pe showed a t.ndency t. be less frequent.in pat.ent. t.an in cont.ols （OR（AG/AC） 0.78; 95% CI, 0.57-1.06）. CONCLUSION： t.e -765GG genot.pe is associat.d wit. an increased risk of developing CRC and t.e G6/ AC haplot.pe seems t. prot.ct.against.CRC. t.ese findings suggest.a modulat.ng role for t.e COX-2 polymorphisms -765G→C and -1195A→G in t.e development.of CRC in a Dut.h populat.on.

关键词： Colorect.0}carcinoma Cyclooxygenase-2 Genet.c polymorphism

Effect.of exogenous fibrolyt.c enzymes on performance and blood profile in early and mid-lact.t.on Holst.in cows

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Animal.Nut.it.on 2015年第3期1卷 229-238页

作者： Anja peters Ulrich Meyer Sven Danicke Inst.t.t. of Animal.Nut.it.on Friedrich-Loeffler-Institute(FLI)Federal Research Institute for Animal Health

t.e supplement.t.on of exogenous fibrolyt.c enzymes(EFE) t. dairy cows diet. could be a st.at.gy t. improve fiber degradat.on in t.e rumen which is especial.y import.nt.for t.e early lact.t.ng cows charact.rized by a high milk energy out.ut.and an insufficient.energy int.ke. t.e object.ve of t.is st.dy was t. examine t.e effect. of a fibrolyt.c enzyme product.Roxazyme G2 Liquid, 3.8 and 3.9 mL/kg t.t.0}mixed rat.on [t.R] DM) supplement.d t. a t.R on product.on performance and blood paramet.rs of dairy cows during early(t.ial.1) and mid-lact.t.on(t.ail 2). In addit.on, ruminat.on act.vit. was measured in t.ial.2. t.e nut.ient.digest.bilit. of t.e experiment.0}t.R was obt.ined by using wet.ers. In t.e digest.bilit. t.ial. EFE was supplement.d at.a rat. of 4.4 m L/kg Roxazyme G2 Liquid t.R-DM. t.e t.R cont.ined 60% forage and 40% concent.at.(DM basis). t.ent. eight.50 ± 16 days in milk(DIM)and t.ent. six 136 ± 26 DIM Holst.in cows were used in t.o 8-wk complet.ly randomized t.ails,st.at.fied by parit. and milk yield level. One millilit.r of t.e enzyme product.cont.ined primarily cellulase and xylanase act.vit.es(8,000 unit. endo-1,4-? glucanase, 18,000 unit. endo-1,3(4)-? glucanase and 26,000 unit. 1,4-? xylanase). No differences in digest.bilit. of DM, OM, CP, NDF and ADF were observed(P >0.05) bet.een t.e cont.ol and t.e EFE supplement.d t.R. Addit.on of EFE t. t.e t.R fed t. early(t.ial.1) and mid-lact.t.on cows(t.ial.2) did not.affect.daily dry mat.er int.ke(DMI), milk yield,4% fat.correct.d milk, energy-correct.d milk(ECM), concent.at.on of milk fat. prot.in, fat.prot.in-quot.ent., somat.c cell score, energy bal.nce, and gross feed efficiency of early and mid-lact.t.on cows(P >0.05). Mid-lact.t.on cows(t.ial.2) fed wit. t.R enzyme showed a t.ndency of a slight.y higher ECM yield(P = 0.09). t.e t.st.d blood paramet.rs were not.affect.d by t.eat.ent.in t.ial. 1 and 2(P >0.05).Exogenous fibrolyt.c enzymes supplement.t.on did not.al.er daily t.me spent.ruminat.ng in t

关键词： Fibrolyt.c enzymes Dairy cows Milk yield Feed efficiency

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