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The climate impact of high seas shipping

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National Science Review 2023年第3期10卷 102-116页

作者： Yuze li peng jia Shangrong jiang Haijiang li Haibo Kuang Yongmiao Hong Shouyang wang Xueting Zhao Dabo guan Questrom School of Business Boston University Collaborative Innovation Center for Transport Studies Dalian Maritime University School of Maritime Economics and Management Dalian Maritime University School of Economics and Management University of Chinese Academy of Sciences Academy of Mathematics and Systems Science Chinese Academy of Sciences Center for Forecasting Science Chinese Academy of Sciences School of Entrepreneurship and Management Shanghai Tech University Department of Earth System Science Tsinghua University School of International Development University of East Anglia

Strict carbon emission regulations are set with respect to countries’ territorial seas or shipping activities in exclusive economic zones to meet their climate change commitment under the Paris ***,no shipping policies on carbon mitigation are proposed for the world’s high seas regions,which results in carbon intensive shipping *** this paper,we propose a Geographic-based Emission Estimation Model(GEEM) to estimate shipping GHG emission patterns on high seas *** results indicate that annual emissions of carbon dioxide equivalent(CO2-e) in shipping on the high seas reached 211.60 million metric tonnes in 2019,accounting for about one-third of all shipping emissions globally and exceeding annual GHG emissions of countries such as *** average emission from shipping activities on the high seas is growing at approximately 7.26% per year,which far surpasses the growth rate of global shipping emission at 2.23%.We propose implementation of policies on each high seas region with respect to the main emission driver identified from our *** policy evaluation results show that carbon mitigation policies could reduce emissons by 25.46 and 54.36 million tonnes CO2-e in the primary intervention stage and overall intervention stage,respectively,with 12.09% and 25.81% reduction rates in comparison to the2019 annual GHG emissions in high seas shipping.

关键词： high seas international shipping GHG emission policy evaluation emission drivers

Effects of early oral feeding after radical total gastrectomy in gastric cancer patients

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World Journal of Gastroenterology 2020年第36期26卷 5508-5519页

作者： Yi-Xun Lu Yan-Jun wang Tian-Yu Xie shuo li Di Wu Xiong-guang li Qi-ying Song li-peng wang Da guan Xin-Xin wang Department of General Surgery Chinese PLA General HospitalBeijing 100853China Department of Surgical Intensive Care Unit Children’s Hospital Affiliated to Zhengzhou UniversityChildren’s Hospital of Henan ProvenceZhengzhou 450018Henan ProvinceChina

BACKGROUND Gastric cancer(GC)is a heavy burden in *** support for GC patients is closely related to postoperative ***,the role of early oral feeding after laparoscopic radical total gastrectomy in GC patients is unclear and high-quality research evidence is *** To prospectively explore the safety,feasibility and short-term clinical outcomes of early oral feeding after laparoscopic radical total gastrectomy for GC *** This study was a prospective cohort study conducted between January 2018 and December 2019 based in a high-volume tertiary hospital in China.A total of 206 patients who underwent laparoscopic radical total gastrectomy for GC were *** which,105 patients were given early oral feeding(EOF group)after surgery,and the other 101 patients were given the traditional feeding strategy(control group)after *** clinical data were recorded and *** primary endpoints were gastrointestinal function recovery time and postoperative complications,and the secondary endpoints were postoperative nutritional status,length of hospital stay and expenses,*** Compared with the control group,patients in the EOF group had a significantly shorter postoperative first exhaust time(2.48±1.17 d vs 3.37±1.42 d,P=0.001)and first defecation time(3.83±2.41 d vs 5.32±2.70 d,P=0.004).In addition,the EOF group had a significant shorter postoperative hospitalization duration(5.85±1.53 d vs 7.71±1.56 d,Plization expenses(16.60±5.10 K¥vs 21.00±7.50 K¥,P=0.014).On the 5th day after surgery,serum prealbumin level(214.52±22.47 mg/L vs 204.17±20.62 mg/L,P=0.018),serum gastrin level(246.30±57.10 ng/L vs 223.60±55.70 ng/L,P=0.001)and serum motilin level(424.60±68.30 ng/L vs 409.30±61.70 ng/L,P=0.002)were higher in the EOF ***,there was no significant difference in the incidence of total postoperative complications between the two groups(P=0.507).CONCLUSION Early

关键词： Gastric cancer Laparoscopic surgery Early oral feeding

Role of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer

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World Journal of Gastrointestinal Oncology 2020年第7期12卷 782-790页

作者： Tian-Yu Xie Di Wu shuo li Zhao-Yan Qiu Qi-ying Song Da guan li-peng wang Xiong-guang li Feng Duan Xin-Xin wang School of Medicine Nankai UniversityTianjin 300071China Department of General Surgery Chinese PLA General HospitalBeijing 100853China

BACKGROUND Gastric cancer is the second most common malignant tumor in China,ranking third among all malignant tumor mortality *** intraperitoneal chemotherapy(HIPEC)has been shown to increase significantly the effectiveness of intraperitoneal chemotherapeutic drugs,prolong the action time of these drugs on intraperitoneal tumor cells,and enhance their diffusion in tumor *** may be one of the best choices for the eradication of residual cancer cells in the abdominal *** The aim of this study was to study the role of preventive HIPEC after radical *** A prospective analysis was performed with patients with c T4 N0-3 M0 gastric cancer to compare the effects of postoperative prophylactic HIPEC plus intravenous chemotherapy with those of routine adjuvant ***’medical records were analyzed,and differences in the peritoneal recurrence rate,diseasefree survival time,and total survival time between groups were *** The first site of tumor recurrence was the peritoneum in 11 cases in the conventional adjuvant chemotherapy group and in 2 cases in the HIPEC group(P=0.020).The 1-year and 3-year disease-free survival rates were 91.9%and 60.4%,respectively,in the conventional adjuvant chemotherapy group and 92.1%and 63.0%,respectively,in the HIPEC *** 1-year and 3-year overall survival rates were 95.2%and 66.3%,respectively,in the conventional adjuvant chemotherapy group and 96.1%and 68.6%,respectively,in the HIPEC *** significant difference in postoperative or chemotherapy complications was observed between *** In patients with c T4 N0-3 M0 gastric cancer,prophylactic HIPEC after radical tumor surgery is beneficial to reduce peritoneal tumor recurrence and prolong survival.

关键词： Hyperthermic intraperitoneal chemotherapy Gastric cancer Prognosis Locally advanced Overall survival Disease-free survival

Microstructural evolution and mechanical properties of in situ nano Ta_(4)HfC_(5) reinforced SiBCN composite ceramics

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Journal of Advanced Ceramics 2020年第6期9卷 739-748页

作者： Bingzhu wang Daxin li Zhihua YANG Dechang jia Jingyi guan Hao peng Delong CAI Peigang HE Xiaoming DUAN Yu ZHOU Tao ZHANG Chenguang GAO Institute for Advanced Ceramics School of Materials Science and EngineeringHarbin Institute of TechnologyHarbin 150001China Key Laboratory of Advanced Structural-Functional Integration Materials&Green Manufacturing Technology Harbin Institute of TechnologyHarbin 150001China State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001China Beijing Institute of Control Engineering Beijing 100080China

The in situ nano Ta_(4)HfC_(5) reinforced SiBCN-Ta_(4)HfC_(5) composite ceramics were prepared by a combination of two-step mechanical alloying and reactive hot-pressing *** microstructural evolution and mechanical properties of the resulting SiBCN-Ta_(4)HfC_(5) were *** the first-step milling of 30 h,the raw materials of TaC and HfC underwent crushing,cold sintering,and short-range interdiffusion to finally obtain the high pure nano Ta_(4)HfC_(5).A hybrid structure of amorphous SiBCN and nano Ta_(4)HfC_(5) was obtained by adopting a second-step *** reactive hot-pressing sintering,amorphous SiBCN has crystallized to 3C-SiC,6H-SiC,and turbostratic BN(C)phases and Ta_(4)HfC_(5) retained the form of the *** the in situ generations of 2.5 wt% Ta_(4)HfC_(5),Ta_(4)HfC_(5) is preferentially distributed within the turbostratic BN(C);however,as Ta_(4)HfC_(5) content further raised to 10 wt%,it mainly distributed in the grain-boundary of BN(C) and *** introduction of Ta_(4)HfC_(5) nanocrystals can effectively improve the flexural strength and fracture toughness of SiBCN ceramics,reaching to 344.1 MPa and 4.52 MPa·m^(1/2),*** work has solved the problems of uneven distribution of ultra-high temperature phases in the ceramic matrix,which is beneficial to the real applications of SiBCN ceramics.

关键词： Ta_(4)HfC_(5) SiBCN microstructure evolution mechanical properties

Perioperative complication incidence and risk factors for retroperitoneal neuroblastoma in children:analysis of 571 patients

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World Journal of Pediatrics 2024年第3期20卷 250-258页

作者： Min He jia-Bin Cai Xuan Wu yin-Bing Tang Jin-Yan wang Jun-Qin Mao Ji-Jun Chen li-Feng Zhang Zhong-Hai guan Jie-Ni Xiong Wan-Xin peng Jin-Hu wang Ting Tao Pediatric Cancer Research Center National Clinical Research Center for Child HealthHangzhouChina Department of Surgical Oncology Children's HospitalZhejiang University School of MedicineHangzhouChina Cancer Center Zhejiang UniversityNo.3333 Binsheng RodeHangzhouChina

Background Surgery plays an important role in the treatment of *** complications may impact the course of neuroblastoma *** date,comprehensive analyses of complications and risk factors have been *** Patients with retroperitoneal neuroblastoma undergoing tumor resection were retrospectively analyzed between 2014 and *** data collected included clinical characteristics,operative details,operative complications and postopera-tive *** factors for perioperative complications of retroperitoneal neuroblastoma were *** A total of 571 patients were enrolled in this *** complications were observed in 255(44.7%)*** leakage(28.4%),diarrhea(13.5%),and injury(vascular,nerve and organ;7.5%)were the most frequent *** were three operation-related deaths(0.53%):massive hemorrhage(n=1),biliary tract perforation(n=1)and intestinal necrosis(n=1).The presence of image-defined risk factors(IDRFs)[odds ratio(OR)=2.09,Plications,the associated mortality rate was quite ***-perative complications of retroperitoneal neuroblastoma were associated with IDRFs,INRGSS,retroperitoneal lymph node metastasis and vascular *** with high-risk factors should receive more serious attention during surgery but should not discourage the determination to pursue total resection of neuroblastoma.

关键词： Complication Neuroblastoma Risk factors Surgery

Corrosion resistance of bioinspired DNA-induced Ca-P coating on biodegradable magnesium alloy

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Journal of Magnesium and Alloys 2019年第1期7卷 144-154页

作者： Ping liu jia-Min wang Xiao-Tong Yu Xiao-Bo Chen shuo-Qi li Dong-Chu Chen Shao-Kang guan Rong-Chang Zeng Lan-Yue Cui College of Materials Science and Engineering Shandong University of Science and TechnologyQingdao 266590China School of Engineering RMIT UniversityCarlton 3053Australia School of Materials Science and Energy Engineering Foshan UniversityFoshan 528000China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450002China

Bioinspired coatings with decreased corrosion rate and enhanced bond strength are at the core of future clinic applications on degradable magnesium(Mg)-based *** hybrid of organic and inorganic compounds offers a strategy to fabricate biodegradable,biocompatible and compact coatings on biomedical Mg ***,a comparison with and without DNA addition was made on the corrosion resistance and adhesion strength of Ca-P coatings fabricated on AZ31 alloy via hydrothermal *** morphology,chemical composition,and crystallographic structure of the coatings were investigated by means of SEM,EDS and FTIR as well as XRD before and after corrosion *** resistance was evaluated via potentiodynamic polarization curves,electrochemical impedance spectroscopy(EIS)and hydrogen evolution tests in Hank’s *** show that the coatings are mainly characterized by tricalcium phosphate(TCP),dicalcium phosphate anhydrous(DCPA)and calcium-deficient hydroxyapatite(CDHA).The presence of DNA leads to the formation of Ca-P coating with improved corrosion resistance and adhesion ***,the formation mechanism for DNA-induced Ca-P coating is *** DNA-induced Ca-P coating exhibits a promising future for controlling the corrosion rate of biodegradable Mg alloys.©2019 Published by Elsevier *** behalf of Chongqing University.

关键词： DNA Corrosion resistance Biodegradability Magnesium alloys Coatings

Clinical characteristics and outcome of autoimmune pancreatitis based on serum immunoglobulin G4 level:A single-center,retrospective cohort study

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World Journal of Gastroenterology 2023年第35期29卷 5125-5137页

作者： guan-Zhou Zhou jia-Qi Zeng Lei wang Miao liu Ke Meng Zi-Kai wang Xiu-li Zhang li-Hua peng Bin Yan Fei Pan Department of Gastroenterology and Hepatology The First Medical CenterChinese PLA General HospitalBeijing 100853China School of Medicine Nankai UniversityTianjin 300071China Chinese PLA Medical School Beijing 100853China Department of Rheumatology The First Medical CenterChinese PLA General HospitalBeijing 100853China Department of Statistics and Epidemiology Graduate SchoolChinese PLA General HospitalBeijing 100853China

BACKGROUND Autoimmune pancreatitis(AIP)has been linked with elevated immunoglobulin(Ig)G4 *** characteristics and outcomes of AIP based on serum markers have not been fully *** To compare clinical features,treatment efficacy,and outcome of AIP based on serum IgG4 levels and analyze predictors of *** A total of 213 patients with AIP were consecutively reviewed in our hospital from 2006 to *** to the serum IgG4 level,all patients were divided into two groups,the abnormal group(n=148)with a high level of IgG4[>2×upper limit of normal(ULN)]and the normal group(n=65).The t-test or Mann-Whitney U test was used to compare continuous *** parameters were compared by theχ^(2) test or Fisher’s exact ***-Meier curves Zhou GZ et *** characteristics and outcome of AIP WJG https://*** 5126 September 21,2023 Volume 29 Issue 35 and log-rank tests were established to assess the cumulative relapse *** and multivariate analyses were used to investigate potential risk factors of AIP *** Compared with the normal group,the abnormal group had a higher average male age(60.3±10.4 vs 56.5±12.9 years,P=0.047);higher level of serum total protein(72.5±7.9 g/L vs 67.2±7.5 g/L,P2×ULN),hazard ratio(HR):3.583;95%confidence interval(CI):1.218–10.545;P=0.020]and IgA(>1×ULN;HR:5.908;95%CI:1.199–29.120;P=0.029)and age>55 years(HR:2.383;95%CI:1.056–5.378;P=0.036)were independent risk factors of *** AIP patient

关键词： Autoimmune pancreatitis Immunoglobulin G4 Clinical characteristics Outcome Relapse Cohort study

Design of S-band photoinjector with high bunch charge and low emittance based on multi-objective genetic algorithm

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Nuclear Science and Techniques 2023年第3期34卷 93-105页

作者： Ze-Yi Dai Yuan-Cun Nie Zi Hui Lan-Xin liu Zi-shuo liu jian-Hua Zhong jia-Bao guan Ji-Ke wang Yuan Chen Ye Zou Hao-Hu li jian-Hua He The Institute for Advanced Studies Wuhan UniversityWuhan 430072China

High-brightness electron beams are required to drive liNAC-based free-electron lasers(FELs)and storage-ring-based synchrotron radiation light *** bunch charge and RMS bunch length at the exit of the liNAC play a crucial role in the peak current;the minimum transverse emittance is mainly determined by the injector of the ***,a photoin-jector with a high bunch charge and low emittance that can simultaneously provide high-quality beams for 4th generation synchrotron radiation sources and FELs is *** design of a 1.6-cell S-band 2998-MHz RF gun and beam dynamics optimization of a relevant beamline are presented in this *** dynamics simulations were performed by combining ASTRA and the multi-objective genetic algorithm NSGA *** effects of the laser pulse shape,half-cell length of the RF gun,and RF parameters on the output beam quality were analyzed and *** normalized transverse emittance was optimized to be as low as 0.65 and 0.92 mm·mrad when the bunch charge was as high as 1 and 2 nC,***,the beam stability properties of the photoinjector,considering misalignment and RF jitter,were simulated and analyzed.

关键词： Electron linear accelerator Photoinjector Beam dynamics Multi-objective genetic algorithm

Beneficial effects exerted by hydroxychloroquine in treating COVID-19 patients via protecting multiple organs

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Science China(life Sciences) 2021年第2期64卷 330-333页

作者： Bo Yu Chenze li peng Chen jia li Hualiang jiang Dao-Wen wang Division of Cardiology Department of Internal Medicine and Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological DisordersTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Shanghai Institute for Advanced Immunochemical Studies and School of life Science and Technology Shanghai Tech UniversityShanghai 201210China

Dear *** coronavirus disease 2019(COVID-19)pandemic caused by widespread infection with the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)(Chen et al.,2020;guan et al.,2020)has led to a global health *** than 3.5 million infections and 246,838 deaths have occurred as of May 4,2020(Saqrane and El Mhammedi,2020),with a rapid upward *** CO VID-19 patients suffer from complicated systemic injuries such as cardiac(Chen et al.,2020)and hepatic(Huang et al.,2020)damages.

关键词： al. organs patients